Find Luxury Hotels in Clayton, MO

    Plan, book, stay with confidence
  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
  • one key icon
    Treat yourself
    Save instantly and earn perks with One Key
    Learn about One Key
  • today icon
    Change your mind
    Book hotels with free cancellation

Pick from 4 Clayton Luxury Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Room
The Ritz-Carlton, St. Louis
5.0 star property
9.2 out of 10, Wonderful, (506)
"Staff, very warming and helpful rooms, clean bright and well maintained"
The price is SAR 1,872
SAR 2,180 total
includes taxes & fees
27 Jum. I - 28 Jum. I
The Ritz-Carlton, St. Louis
Exterior
Clayton Plaza Hotel & Extended Stay
3.5 star property
8.8 out of 10, Excellent, (2871)
"We have stayed at this hotel several times this past year since our son attended WashU. If you are looking for something close to campus, and a good value, this is a great hotel. It is no frills & a little “tired,” but is clean and the staff is amazing. Since we just want a place to sleep, this works great for us!"
The price is SAR 428
SAR 484 total
includes taxes & fees
2 Jum. II - 3 Jum. II
Clayton Plaza Hotel & Extended Stay
Room
Le Méridien St. Louis Clayton
4.0 star property
8.8 out of 10, Excellent, (463)
"The pool wasn’t open! The baseboard was quite dirty in bathroom of 1109…staff was phenomenal!"
The price is SAR 705
SAR 808 total
includes taxes & fees
23 Jum. I - 24 Jum. I
Le Méridien St. Louis Clayton
Property entrance
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
8.4 out of 10, Very Good, (542)
"Cute little inn in with great options within walking distance. "
The price is SAR 495
SAR 567 total
includes taxes & fees
9 Jum. II - 10 Jum. II
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Don't see what you're looking for?
See all available properties in Clayton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Are you looking for a luxury hotel for your stay in Clayton?
Expedia can help you arrange a flight to St. Louis Lambert Intl. Airport (STL) airport or St. Louis, MO (SUS-Spirit of St. Louis) airport, and then you can select from various places to stay that will deliver the luxury you’d like to find. Amenities are important when you plan a trip, so we make it easy to find what you need to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Clayton has to offer. While you’re visiting, you might want to think about enjoying the museums and sporting events, which Clayton is known for.
What's the best time to vacation in Clayton?
The hottest months are usually July and August with an average temperature of 76°F,
  • Coldest months: January, February, December, and March
  • Driest months: January, February, December, and November
  • Rainiest months: April, May, June, and August
What's there to see and do in Clayton?
Experience Clayton with a stop at Chapel of St. Timothy And St. Titus, Concordia Seminary, St. Louis Zoo, and St. Louis Union Station. If you have extra time while you’re in the area, you might want to see Busch Stadium and Gateway Arch.
How can I get around Clayton?
It’s easier to get around town comfortably when you know your options. Head to Clayton Station for metro transit.

Recent reviews of Clayton hotels
Expedia verified reviews

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

5/5 Excellent
"this was great hotel and has shuttle for easy access to airport and also close to car rental returns "
A verified traveler stayed at Renaissance St. Louis Airport Hotel
Posted 5 hours ago
Renaissance St. Louis Airport Hotel