The illuminated Gateway Arch at night with a city skyline in the background.

Find 5 Star Hotels in Clayton, MO from SAR 541

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Clayton 5 Star Hotels

Our top choices for Clayton 5-star hotels

Terrace/patio

1. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,007 reviews)
"The absolute best place to stay in St Louis."
United States
Brandy
The price is SAR 1,408
SAR 1,647 total
includes taxes & fees
16 Sep - 17 Sep
Four Seasons Hotel St Louis
Meeting facility

2. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (586 reviews)
"Incredible stay! Loved the room, the staff were great, and the amenities were amazing! Definitely recommend staying here!"
United States
Kennedy
The price is SAR 2,062
SAR 2,407 total
includes taxes & fees
20 Sep - 21 Sep
The Ritz-Carlton, St. Louis
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Clayton.
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

9801 Natural Bridge Road St. Louis MO
The price is SAR 463 per night from Oct 2 to Oct 3
SAR 463
SAR 541 total
2 Oct - 3 Oct
includes taxes & fees
8.4/10 Very Good! (1,173 reviews)
Still don't see what you're looking for?
See all properties in Clayton.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Clayton Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Clayton?
Treat yourself to a luxurious stay at The Ritz-Carlton, St. Louis. This is among the leading 5-star hotels in Clayton based on Expedia guest reviews. From its plush guest rooms to its premium amenities and services, you can count on impeccable quality from the moment you arrive.
How much does it cost to stay in a 5-star hotel in Clayton?
The amount you pay for a 5-star hotel in Clayton can vary according to when you prefer to travel and how long you plan to stay, among other factors. Take advantage of our price per night filter and other search tools to score the best deal on an indulgent stay.

  • Search for the lowest price per night from SAR 541

What makes a hotel 5 stars in Clayton?
Exceptional guest service is at the heart of every 5-star hotel in Clayton. From the moment you enter the lobby, staff cater to your every whim, whether recommending activities and tours or providing a nightly turn-down service. Additionally, hotels must feature superior amenities to be entitled to a 5-star rating. These can include luxury baths, a wellness center, swimming pools, fine dining kitchens and knowledgeable concierge.