The illuminated Gateway Arch at night with a city skyline in the background.

Find 4 Star Hotels in Clayton, MO from SAR 424

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Check availability on Clayton 4 Star Hotels

Next weekend
6 Nov - 8 Nov
In two weeks
13 Nov - 15 Nov

Our top choices for Clayton 4-star hotels

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

1. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,389 reviews)
"Great location and great place to visit"
United States
Tracy
The price is SAR 469
SAR 554 total
includes taxes & fees
25 Nov - 26 Nov
Hyatt Regency St. Louis at The Arch
A bar area with high wooden ceilings, a large mural, and a variety of seating options including tables and bar stools.

2. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (2,138 reviews)
"Wonderful Stay!"
United States
A.R.
The price is SAR 539
SAR 649 total
includes taxes & fees
22 Nov - 23 Nov
21C Museum Hotel St Louis
A buffet with fruits, pastries, and beverages.

3. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very good, (1,191 reviews)
"Great Hotel."
United States
Joy
The price is SAR 417
SAR 488 total
includes taxes & fees
20 Nov - 21 Nov
Renaissance St. Louis Airport Hotel
A rooftop restaurant with round tables, chairs, and a view of the city.

4. Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (2,052 reviews)
"Great location."
United States
Jennifer
The price is SAR 568
SAR 675 total
includes taxes & fees
18 Nov - 19 Nov
Moonrise Hotel
A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

5. Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,360 reviews)
"Great place to stay."
United States
brandon
The price is SAR 522
SAR 620 total
includes taxes & fees
15 Nov - 16 Nov
Live by Loews - St.Louis
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

6. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,086 reviews)
"Great place"
United States
Samuel
The price is SAR 597
SAR 761 total
includes taxes & fees
16 Nov - 17 Nov
Ameristar Casino Resort and Spa
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

7. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.2 out of 10, Wonderful, (1,001 reviews)
"The hotel is beautiful, and we really enjoyed the restaurants--The Tenderloin Room was especially delicious!"
United States
Sara
The price is SAR 503
SAR 704 total
includes taxes & fees
22 Nov - 23 Nov
The Royal Sonesta Chase Park Plaza St. Louis
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.

8. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (799 reviews)
"Beautiful hotel in a convenient location."
United States
Marsha
The price is SAR 571
SAR 672 total
includes taxes & fees
8 Nov - 9 Nov
Le Méridien St. Louis Clayton
A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.

9. The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,004 reviews)
"Amazing property, staff was very friendly, great location!!"
United States
Stacy
The price is SAR 492
SAR 575 total
includes taxes & fees
15 Nov - 16 Nov
The Westin St. Louis
A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

10. Marriott St. Louis Airport

Marriott St. Louis Airport
4.0 star property
Edmundson
8.0 out of 10, Very good, (1,001 reviews)
"Good food an"
United States
Ravyn
The price is SAR 535
SAR 644 total
includes taxes & fees
13 Nov - 14 Nov
Marriott St. Louis Airport
A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

11. River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,832 reviews)
"Great accommodations - highly recommend"
United States
jodi
The price is SAR 327
SAR 439 total
includes taxes & fees
2 Dec - 3 Dec
River City Casino & Hotel
A multi-story hotel with a prominent 'Marriott' sign, featuring a classic architectural style with a red brick facade and large windows.

12. Marriott St. Louis Grand

Marriott St. Louis Grand
4.0 star property
Downtown St. Louis
8.4 out of 10, Very good, (1,001 reviews)
"Great location, clean, nice bar area, full service Starbucks, very helpful staff!"
United States
Leonor
The price is SAR 477
SAR 567 total
includes taxes & fees
22 Nov - 23 Nov
Marriott St. Louis Grand
A bar area with a central bar, multiple stools, and a chandelier.

13. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,401 reviews)
"Gorgeous historic hotel close to all main downtown sightseeings."
United States
Anastasia
The price is SAR 357
SAR 424 total
includes taxes & fees
23 Nov - 24 Nov
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

14. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,000 reviews)
"Really enjoyed the breakfast and happy hours!"
United States
Stacey Rochelle
The price is SAR 480
SAR 570 total
includes taxes & fees
22 Nov - 23 Nov
Drury Plaza Hotel St. Louis Brentwood
A cozy lounge area with leather sofas, a fireplace, and a bar counter.

15. The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.8 out of 10, Excellent, (1,002 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
The price is SAR 557
SAR 661 total
includes taxes & fees
22 Nov - 23 Nov
The Cheshire
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

16. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
9.0 out of 10, Wonderful, (1,365 reviews)
"Loved our stay!"
United States
Megan
The price is SAR 427
SAR 508 total
includes taxes & fees
23 Nov - 24 Nov
Embassy Suites by Hilton St. Louis Downtown
A rooftop terrace with outdoor seating, string lights, and a city skyline view.

17. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
Grand Center
8.8 out of 10, Excellent, (1,172 reviews)
"Always our top pick to stay when in town for travel. Great people, Great vibes and a Great distance from alot of downtown hot spots ☺️"
United States
Skylee
The price is SAR 388
SAR 457 total
includes taxes & fees
22 Nov - 23 Nov
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
A modern lounge area with a central fire feature, seating, and large windows offering a city view.

18. Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1,291 reviews)
"AMAZING STAY! AMAZING VIEWS FEOM ROOFTOP BAR!"
United States
Kella
The price is SAR 520
SAR 619 total
includes taxes & fees
22 Nov - 23 Nov
Hilton St. Louis at the Ballpark
A spacious lobby with high arched ceilings, ornate columns, and a central fountain.

19. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.8 out of 10, Excellent, (1,000 reviews)
"Front desk staff was very helpful in answering question about the property and surrounding area!"
United States
William
The price is SAR 582
SAR 692 total
includes taxes & fees
22 Nov - 23 Nov
St. Louis Union Station Hotel, Curio Collection by Hilton
A spacious lobby with modern seating arrangements, a large chandelier, and a view of the cityscape through large windows.

20. Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,159 reviews)
"Great staff and clean room along as well as th restaurant was clean too."
United States
Tabitha
The price is SAR 412
SAR 481 total
includes taxes & fees
15 Nov - 16 Nov
Hilton Pennywell St. Louis at the Arch
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Clayton.
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO
The price is SAR 1,407 per night from Nov 2 to Nov 3
SAR 1,407
SAR 1,646 total
2 Nov - 3 Nov
includes taxes & fees
9.4/10 Exceptional! (1,002 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Clayton Hotel Reviews

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

8/10 Good
"It was a lovely room, great location and I have no complaints. I would stay there again."
Margaretta 1-night trip
Posted 9 hours ago
Hyatt Regency St. Louis at The Arch
Live by Loews - St.Louis

Live by Loews - St.Louis

10/10 Excellent
"Hotel and room were very clean. Beds were very comfortable. On site bar was convenient."
Kacey 1-night trip
Posted 12 hours ago
Live by Loews - St.Louis

Frequently asked questions

What are the best 4-star hotels in Clayton?
Le Méridien St. Louis Clayton is a 4-star hotel in Clayton that ranks highly among Expedia guests. A swimming pool and a terrace are just a couple of its amenities. Travelers also recommend The Cheshire. From designer toiletries to a pillowtop mattress, it offers conveniences that cater to every aspect of your enjoyment and relaxation.
How much does it cost to stay in a 4-star hotel in Clayton?
With Expedia's search and sort filters, locking in a superb deal on a 4-star hotel in Clayton just got easier. Start by entering your chosen travel dates and length of your stay. Then sort the results by price and pick the option that best fits your style and budget.

  • Search for the lowest price from SAR 1,646

What's the difference between 5-star and 4-star hotels in Clayton?
If you choose to vacation at a 4-star hotel in Clayton, you'll usually find loads of conveniences to ensure you're comfortable, such as a restaurant, pool and gym. You can look forward to high-quality service and upscale surroundings. Go for a 5-star hotel and you'll get a few extra bells and whistles — think on-site spas, 24-hour front desk and opulent turndown services. You're likely to get extra amenities and premium services at a 5-star retreat, but both are awesome options for luxury guests.