The illuminated Gateway Arch at night with a city skyline in the background.

Find 4 Star Hotels in Clayton, MO from SAR 479

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Clayton 4 Star Hotels

Next weekend
2 Oct - 4 Oct
In two weeks
9 Oct - 11 Oct

Our top choices for Clayton 4-star hotels

Meeting facility

1. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very good, (1,188 reviews)
"Great stay"
United States
Anthony
The price is SAR 444
SAR 519 total
includes taxes & fees
15 Oct - 16 Oct
Renaissance St. Louis Airport Hotel
Lobby

2. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,314 reviews)
"Great Stay"
United States
Timothy
The price is SAR 503
SAR 594 total
includes taxes & fees
2 Oct - 3 Oct
Hyatt Regency St. Louis at The Arch
Exterior

3. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (2,120 reviews)
"Great place to stay!"
United States
Zane
The price is SAR 539
SAR 649 total
includes taxes & fees
18 Oct - 19 Oct
21C Museum Hotel St Louis
Gastropub

4. The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.8 out of 10, Excellent, (1,006 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
The price is SAR 557
SAR 662 total
includes taxes & fees
11 Oct - 12 Oct
The Cheshire
Breakfast, lunch and dinner served

5. Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,342 reviews)
"Great hotel"
United States
Frank
The price is SAR 597
SAR 710 total
includes taxes & fees
4 Oct - 5 Oct
Live by Loews - St.Louis
Premium bedding, down comforters, pillowtop beds, in-room safe

6. The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,010 reviews)
"Location was perfect for getting around."
United States
Joanne
The price is SAR 492
SAR 576 total
includes taxes & fees
18 Oct - 19 Oct
The Westin St. Louis
Seasonal outdoor pool

7. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.2 out of 10, Wonderful, (1,012 reviews)
"Loved the location and everything about this place. Will definitely stay again"
United States
Tosha
The price is SAR 559
SAR 770 total
includes taxes & fees
4 Oct - 5 Oct
The Royal Sonesta Chase Park Plaza St. Louis
5 restaurants; breakfast, lunch, dinner, and brunch served

8. River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,803 reviews)
"Would definitely stay here again!"
United States
Ashley
The price is SAR 365
SAR 479 total
includes taxes & fees
15 Oct - 16 Oct
River City Casino & Hotel
Terrace/patio

9. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
Grand Center
8.8 out of 10, Excellent, (1,162 reviews)
"Great comfortable hotel with easy access and parking. Good location. Would stay again."
Canada
Timothy
The price is SAR 443
SAR 523 total
includes taxes & fees
5 Oct - 6 Oct
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Outdoor pool, open 10:00 AM to 6:00 PM, cabanas (surcharge)

10. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,060 reviews)
"Always a great place to stay!"
United States
Melissa
The price is SAR 560
SAR 717 total
includes taxes & fees
12 Oct - 13 Oct
Ameristar Casino Resort and Spa
Exterior

11. Marriott St. Louis Grand

Marriott St. Louis Grand
4.0 star property
Downtown St. Louis
8.2 out of 10, Very good, (1,007 reviews)
"Great hotel"
United States
Andrew
The price is SAR 571
SAR 679 total
includes taxes & fees
3 Oct - 4 Oct
Marriott St. Louis Grand
Property amenity

12. Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (2,022 reviews)
"Great location, clean rooms, and friendly staff. We will definitely stay again."
United States
Nicole
The price is SAR 496
SAR 589 total
includes taxes & fees
11 Oct - 12 Oct
Moonrise Hotel
Lobby lounge

13. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,016 reviews)
"Excellent place to stay. Beautiful hotel, amazing friendly and attentive staff. Would highly recommend!!"
United States
Janell
The price is SAR 511
SAR 606 total
includes taxes & fees
4 Oct - 5 Oct
Drury Plaza Hotel St. Louis Brentwood
Exterior

14. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
9.0 out of 10, Wonderful, (1,353 reviews)
"Beautiful place to stay"
United States
Karen
The price is SAR 428
SAR 509 total
includes taxes & fees
11 Oct - 12 Oct
Embassy Suites by Hilton St. Louis Downtown
3 bars/lounges, rooftop bar

15. Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1,272 reviews)
"right next to the ballpark, fun upstairs club, great downstairs bar, lots of fun stuff right around ballpark village, would def stay again"
United States
Scott
The price is SAR 551
SAR 655 total
includes taxes & fees
3 Oct - 4 Oct
Hilton St. Louis at the Ballpark
Exterior

16. Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
Frontenac
8.8 out of 10, Excellent, (1,000 reviews)
"This is one of our favorite hotels to stay at and the staff is top notch!!"
United States
Michael and Julie
The price is SAR 551
SAR 642 total
includes taxes & fees
4 Oct - 5 Oct
Hilton St. Louis Frontenac
Outdoor pool, open 8:00 AM to 8:00 PM, pool umbrellas, sun loungers

17. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (781 reviews)
"Staff was outstanding. Location and room ideal."
United States
Steven
The price is SAR 571
SAR 673 total
includes taxes & fees
4 Oct - 5 Oct
Le Méridien St. Louis Clayton
Restaurant

18. Marriott St. Louis Airport

Marriott St. Louis Airport
4.0 star property
Edmundson
8.0 out of 10, Very good, (1,001 reviews)
"This place was pretty close to the airport so it was good for a layover. They had nice dining options right there in the hotel."
United States
Chris
The price is SAR 558
SAR 666 total
includes taxes & fees
2 Oct - 3 Oct
Marriott St. Louis Airport
Bar (on property)

19. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,376 reviews)
"Great place"
United States
Carol
The price is SAR 473
SAR 563 total
includes taxes & fees
25 Oct - 26 Oct
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Lobby

20. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.8 out of 10, Excellent, (1,011 reviews)
"Such a fun hotel. Fun for all age groups We will be back for sure"
United States
Mirjana
The price is SAR 723
SAR 860 total
includes taxes & fees
4 Oct - 5 Oct
St. Louis Union Station Hotel, Curio Collection by Hilton
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Clayton.
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO
The price is SAR 1,408 per night from Oct 4 to Oct 5
SAR 1,408
SAR 1,646 total
4 Oct - 5 Oct
includes taxes & fees
9.4/10 Exceptional! (1,002 reviews)
Still don't see what you're looking for?
See all properties in Clayton.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Clayton Hotel Reviews

Live by Loews - St.Louis

Live by Loews - St.Louis

10/10 Excellent
"Wonderful stay. Comfy bed. One of cleanest rooms I’ve ever stayed in. It is convenient to Busch Stadium, but just a heads up that if you stay there, any of the events may be cause for a bit of noise - but with the television on, it just sounded like any metropolitan area. Would not hesitate to stay again."
Lianne 1-night trip
Posted 1 hour ago
Live by Loews - St.Louis

Frequently asked questions

What are the best 4-star hotels in Clayton?
Le Méridien St. Louis Clayton is a 4-star hotel in Clayton that ranks highly among Expedia guests. A swimming pool and a terrace are just a couple of its amenities. Travelers also recommend The Cheshire. From designer toiletries to a pillowtop mattress, it offers conveniences that cater to every aspect of your enjoyment and relaxation.
How much does it cost to stay in a 4-star hotel in Clayton?
With Expedia's search and sort filters, locking in a superb deal on a 4-star hotel in Clayton just got easier. Start by entering your chosen travel dates and length of your stay. Then sort the results by price and pick the option that best fits your style and budget.

  • Search for the lowest price from SAR 1,646

What's the difference between 5-star and 4-star hotels in Clayton?
If you choose to vacation at a 4-star hotel in Clayton, you'll usually find loads of conveniences to ensure you're comfortable, such as a restaurant, pool and gym. You can look forward to high-quality service and upscale surroundings. Go for a 5-star hotel and you'll get a few extra bells and whistles — think on-site spas, 24-hour front desk and opulent turndown services. You're likely to get extra amenities and premium services at a 5-star retreat, but both are awesome options for luxury guests.