Find 5 Star Hotels in Otay Mesa, CA from SAR176

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Compare Otay Mesa 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Front of property - evening/night
Pendry San Diego
5.0 star property
9.4 out of 10, Exceptional, (1001)
"Full service hotel, and fantastic location. Accommodating staff, great timing options right in the hotel, as well as ample dining in the gaslamp district."
The price is SAR 1,100
SAR 1,393 total
includes taxes & fees
7 Jum. II - 8 Jum. II
Pendry San Diego
Exterior
THE US GRANT, a Luxury Collection Hotel, San Diego
5.0 star property
9.0 out of 10, Wonderful, (1002)
"Overall fine property"
The price is SAR 985
SAR 1,096 total
includes taxes & fees
16 Jum. II - 17 Jum. II
THE US GRANT, a Luxury Collection Hotel, San Diego

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Otay Mesa.
Wyndham San Diego Bayside

Wyndham San Diego Bayside

1355 N Harbor Drive, San Diego, CA
The price is SAR176 per night from May 30 to May 31
SAR176
per night
May 30 - May 31
8/10 Very Good! (5,887 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Otay Mesa?
The amount you pay for a 5-star hotel in Otay Mesa can vary depending on when you decide to travel and how long you plan to be away, among a number of factors. Take advantage of our price per night filter and other search tools to score the best deal on a luxurious getaway.

  • Search for the lowest price per night from SAR176

What makes a hotel 5 stars in Otay Mesa?
From high-end dining venues and 24-hour fitness centers to pools and superior bedding, the 5-star experience in Otay Mesa is all about relaxation and luxury. But it requires more than just top-notch amenities to earn a 5-star rating. Hotels must also deliver superb guest-focused services like in-room massage treatments, on-site dry cleaning and laundry and 24-hour room service.
Are there any 5-star all-inclusive resorts in Otay Mesa?
Find a luxury retreat that includes your room, meals, activities and entertainment in Otay Mesa with Expedia’s filter tool. Search for resorts with a 5-star rating and select the “All inclusive” filter. Double-check what’s included in the upfront price. That way, you’re ready to take advantage of the many perks on offer from the moment you arrive.
Are there any 5-star vacation rentals in Otay Mesa?
Although there aren’t any 5-star vacation rentals in Otay Mesa on our site, we have a range of escapes that promise a fantastic getaway. Find one that suits your style by checking out our vacation rentals in Otay Mesa.