Find Luxury Hotels in Otay Mesa, CA

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    one key icon
    Treat yourself
    Save instantly and earn perks with One Key
    Learn about One Key
    today icon
    Change your mind
    Book hotels with free cancellation

Pick from 1 Otay Mesa Luxury Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Exterior
Quality Suites San Diego Otay Mesa
2.5 star property
7.2 out of 10, Good, (1000)
"Muy buena opción si llegas tarde. "
The price is SAR 334
SAR 370 total
includes taxes & fees
4 Jum. II - 5 Jum. II
Quality Suites San Diego Otay Mesa
Don't see what you're looking for?
See all available properties in Otay Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Otay Mesa?
Use Expedia to arrange your flight to Tijuana Intl. Airport (TIJ) airport or San Diego Intl. Airport (SAN) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a vacation, so we make it easy to get what you want to make your stay special. If you want a posh hotel that has fine dining, a spa, or several swimming pools, Expedia can help you find the best luxury hotel experience that Otay Mesa has to offer. During your visit, you might want to enjoy the restaurants which Otay Mesa is known for.
What's the best time to vacation in Otay Mesa?
The hottest months are usually August and September with an average temperature of 71°F,
  • Coldest months: February, January, December, and March
  • Driest months: June, July, September, and August
  • Rainiest months: December, February, January, and March
What's there to see and do in Otay Mesa?
Enjoy Otay Mesa and visit San Diego Zoo, San Ysidro Border Crossing, and Petco Park. If you have a bit of extra time while you’re in the area, you might want to check out Balboa Park and USS Midway Museum.

Recent reviews of Otay Mesa hotels
Expedia verified reviews

Kings Inn San Diego

Kings Inn San Diego

5/5 Excellent
"Great"
A verified traveler stayed at Kings Inn San Diego
Posted 13 hours ago
Kings Inn San Diego