Find Luxury Hotels in St. Charles, MO
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on St. Charles Luxury Hotels
Top St. Charles Luxury Hotels

Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
8.4 out of 10, Very Good, (1009)
The price is SAR 698
SAR 878 total
includes taxes & fees
17 Jul - 18 Jul

Country Inn & Suites by Radisson, St. Charles Historic District
Country Inn & Suites by Radisson, St. Charles Historic District
9.4 out of 10, Exceptional, (1008)
The price is SAR 427
SAR 491 total
includes taxes & fees
20 Jul - 21 Jul

Relax Inn Saint Charles
Relax Inn Saint Charles
6.4 out of 10, (929)
The price is SAR 236
SAR 272 total
includes taxes & fees
15 Jul - 16 Jul

Baymont by Wyndham St. Charles
Baymont by Wyndham St. Charles
8.0 out of 10, Very Good, (1004)

Embassy Suites by Hilton St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles
8.8 out of 10, Excellent, (1101)
The price is SAR 570
SAR 656 total
includes taxes & fees
27 Jul - 28 Jul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of St. Charles hotels
Recent reviews of St. Charles hotels

Clayton Plaza Hotel & Extended Stay
5/5 Excellent
"Great hotel, I loved the room had no carpet, a beautiful clean floor. Excellent breakfast."
A verified traveler from Smyrna stayed at Clayton Plaza Hotel & Extended Stay
Posted 1 day ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Top neighborhoods for Luxury Hotels
Find More Hotels near St. Charles
More Hotel Options in St. Charles
- Adventure Hotels in St. Charles
- Business Hotels in St. Charles
- Casinos in St. Charles
- Cheap Hotels in St. Charles
- Family Hotels in St. Charles
- Golf Hotels in St. Charles
- Historic Hotels in St. Charles
- Hotel Wedding Venues in St. Charles
- Hotel with a Concierge in St. Charles
- Hotels with Bars in St. Charles
- Hotels with Free Parking in St. Charles
- Hotels with Hot Tubs in St. Charles
- Hotels with WiFi in St. Charles
- Hotels with a Pool in St. Charles
- Hotels with an Indoor Pool in St. Charles
- Hotels with smoking rooms in St. Charles
- Pet-friendly Hotels in St. Charles
- Resorts & Hotels with Spas in St. Charles
- Romantic Hotels in St. Charles
- Shopping Hotels in St. Charles
- Winery Hotels in St. Charles
Hotels near popular St. Louis Attractions
- Hotels near Ameristar Casino St. Charles
- Hotels near Historic Main Street
- Hotels near St Charles Convention Center
- Hotels near Lindenwood University
- Hotels near Family Arena
- Hotels near Fast Lane Classic Cars
- Hotels near Katy Trail
- Hotels near Lewis & Clark Boathouse and Nature Center
- Hotels near Missouri Bluffs Golf Course
- Hotels near First Missouri State Capitol Historic Site
St. Charles Hotels by Star Rating
Explore more hotels
- Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
- Hollywood Casino & Hotel St. Louis
- 21C Museum Hotel St Louis
- Best Western St. Louis-Kirkwood Route 66
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Days Inn and Suites by Wyndham St. Louis/Westport Plaza
- Hilton St. Louis at the Ballpark
- Renaissance St. Louis Airport Hotel
- AC Hotel St. Louis Clayton
- Wingate by Wyndham St. Louis/Fenton Route 66
- Casino Queen Hotel
- Forest Park Hotel by MDR
- Pear Tree Inn St. Louis Airport
- Drury Inn & Suites St. Louis Union Station
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- DoubleTree by Hilton St. Louis Airport
- Comfort Inn & Suites
- Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
- River City Casino & Hotel
- The Royal Sonesta Chase Park Plaza St. Louis