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Our top choices for Historic Main Street hotels

Country Inn & Suites by Radisson, St. Charles Historic District
Country Inn & Suites by Radisson, St. Charles Historic DistrictSt. Charles Historic District, 1 km from Historic Main Street
9.4 out of 10, Exceptional, (1,012 reviews)
The price is SAR 513
SAR 590 total
includes taxes & fees
3 May - 4 May

Drury Plaza Hotel St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles1.8 km from Historic Main Street
9.6 out of 10, Exceptional, (1,000 reviews)
The price is SAR 544
SAR 630 total
includes taxes & fees
24 May - 25 May

Hampton Inn & Suites St. Charles Old Town Area
Hampton Inn & Suites St. Charles Old Town Area1.5 km from Historic Main Street
9.0 out of 10, Wonderful, (682 reviews)
The price is SAR 507
SAR 606 total
includes taxes & fees
10 May - 11 May

Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa1.4 km from Historic Main Street
8.6 out of 10, Excellent, (1,000 reviews)
The price is SAR 597
SAR 760 total
includes taxes & fees
12 May - 13 May

Comfort Suites St Charles - St Louis
Comfort Suites St Charles - St Louis1.5 km from Historic Main Street
8.4 out of 10, Very Good, (1,004 reviews)
The price is SAR 351
SAR 403 total
includes taxes & fees
10 May - 11 May

Tru by Hilton St. Charles St. Louis, MO
Tru by Hilton St. Charles St. Louis, MO2.1 km from Historic Main Street
8.6 out of 10, Excellent, (819 reviews)
The price is SAR 458
SAR 531 total
includes taxes & fees
24 May - 25 May

Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis3 km from Historic Main Street
8.4 out of 10, Very Good, (2,191 reviews)
The price is SAR 413
SAR 536 total
includes taxes & fees
4 May - 5 May

Holiday Inn St. Louis Arpt West-Earth City by IHG
Holiday Inn St. Louis Arpt West-Earth City by IHG2.9 km from Historic Main Street
7.6 out of 10, Good, (1,002 reviews)
The price is SAR 330
SAR 380 total
includes taxes & fees
10 May - 11 May

Elimwood Hotel, a Ramada by Wyndham
Elimwood Hotel, a Ramada by Wyndham3.1 km from Historic Main Street
7.4 out of 10, Good, (1,001 reviews)
The price is SAR 392
SAR 454 total
includes taxes & fees
10 May - 11 May

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
Americas Best Value Inn & Suites St. Louis, St. Charles Inn1.6 km from Historic Main Street
5.6 out of 10, (1,004 reviews)
The price is SAR 287
SAR 333 total
includes taxes & fees
30 Apr - 1 May

Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Airport10.6 km from Historic Main Street
9.4 out of 10, Exceptional, (2,943 reviews)
The price is SAR 375
SAR 442 total
includes taxes & fees
3 May - 4 May

Residence Inn by Marriott St. Louis Chesterfield
Residence Inn by Marriott St. Louis Chesterfield15.1 km from Historic Main Street
9.6 out of 10, Exceptional, (214 reviews)
The price is SAR 709
SAR 829 total
includes taxes & fees
22 May - 23 May

Drury Inn & Suites St. Louis St. Peters
Drury Inn & Suites St. Louis St. Peters12 km from Historic Main Street
9.4 out of 10, Exceptional, (1,008 reviews)
The price is SAR 413
SAR 474 total
includes taxes & fees
3 May - 4 May

Sonesta Simply Suites St Louis Earth City
Sonesta Simply Suites St Louis Earth City3.3 km from Historic Main Street
8.8 out of 10, Excellent, (868 reviews)
The price is SAR 316
SAR 363 total
includes taxes & fees
30 Apr - 1 May

Drury Plaza Hotel St. Louis Chesterfield
Drury Plaza Hotel St. Louis Chesterfield15.8 km from Historic Main Street
9.6 out of 10, Exceptional, (1,149 reviews)
The price is SAR 510
SAR 592 total
includes taxes & fees
3 May - 4 May

Hyatt Place St. Louis/Chesterfield
Hyatt Place St. Louis/Chesterfield15.9 km from Historic Main Street
9.6 out of 10, Exceptional, (1,004 reviews)
The price is SAR 521
SAR 605 total
includes taxes & fees
10 May - 11 May

SpringHill Suites by Marriott St. Louis Airport/Earth City
SpringHill Suites by Marriott St. Louis Airport/Earth City4.2 km from Historic Main Street
8.8 out of 10, Excellent, (1,000 reviews)
The price is SAR 461
SAR 547 total
includes taxes & fees
10 May - 11 May

Wingate by Wyndham St. Louis Airport
Wingate by Wyndham St. Louis Airport10.7 km from Historic Main Street
9.2 out of 10, Wonderful, (1,592 reviews)
The price is SAR 449
SAR 529 total
includes taxes & fees
5 May - 6 May

Drury Inn & Suites St. Louis Airport
Drury Inn & Suites St. Louis Airport11.3 km from Historic Main Street
9.2 out of 10, Wonderful, (1,213 reviews)
The price is SAR 431
SAR 506 total
includes taxes & fees
3 May - 4 May

Courtyard by Marriott St. Louis St. Peters
Courtyard by Marriott St. Louis St. Peters8.6 km from Historic Main Street
9.0 out of 10, Wonderful, (712 reviews)
The price is SAR 424
SAR 506 total
includes taxes & fees
26 May - 27 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels close to Historic Main Street
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Country Inn & Suites by Radisson, St. Charles Historic District | 9.4 Exceptional 1,012 reviews | View | ||||||
![]() Drury Plaza Hotel St. Louis St. Charles | 9.6 Exceptional 1,000 reviews | View | ||||||
![]() Hampton Inn & Suites St. Charles Old Town Area | 9.0 Wonderful 682 reviews | View | ||||||
![]() Ameristar Casino Resort and Spa | 8.6 Excellent 1,000 reviews | View | ||||||
![]() Comfort Suites St Charles - St Louis | 8.4 Very Good 1,004 reviews | View |
Top Historic Main Street Hotel Reviews

Ameristar Casino Resort and Spa
8/10 Good
Hotels near other Historic Main Street attractions
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Other Hotels near Historic Main Street, St. Charles Historic District
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Explore more hotels
- Hearth & Harvest | Cozy Farmhouse-Inspired 2BDR
- Luxurious, spa-like retreat steps from Main St.
- The Bourbon & Brass | Speakeasy-Inspired 2BDR
- The St. Charles Guest House, lovely historic home, fun for families and groups
- Stylish 2BR Retreat | Concrete & Canopy
- The Oak & Aura Retreat
- Modern Boutique Stay w/ Plush King Bed- Hare Suite
- The Sterling Stay | Modern Elegant 2-Bedroom
- Rhythm Loft Above the Honky Tonk
- Calming, Chic Space w/ Natural Light- Owl Suite
- Intimate Suite – Perfect for Date Nights-Fox Suite
- Downtown Boutique Comfort w/ Style- Otter Suite








































































