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Find hotels in Santa Ana, Panama City from SAR 92

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Discover 1,575 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Casco View Apartments

3.5 star property
Santa Ana
9.2 out of 10, Wonderful, (50)
"Great stay, would recommend."
United States
Brooke
Casco View Apartments

Hotel República

2.0 star property
Santa Ana
6.6 out of 10, (180)
"Fantastic customer service"
United States
OLGA
Hotel República

Hostal La Cigarra

2.0 star property
Santa Ana
7.6 out of 10, Good, (54)
"Helpful staff, secure, close to sights"
Australia
Suzanne
The price is SAR 83
SAR 92 total
includes taxes & fees
23 Nov - 24 Nov
Hostal La Cigarra

ART CASCO The Hotel

2.0 star property
Santa Ana
5.8 out of 10, (10)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
ART CASCO The Hotel

La Manzana by Wynwood House

3.0 star property
Santa Ana
7.2 out of 10, Good, (15)
"Great hotel. Very close to Casco viejo"
United States
LUCILA
The price is SAR 181
SAR 274 total
includes taxes & fees
24 Nov - 25 Nov
La Manzana by Wynwood House

Room-sofa Bed Stay Rooftop Pool & Gym, A

2.0 star property
Santa Ana
2.0 out of 10, (1)
"You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money"
United States
Cristian Camilo Betancur
The price is SAR 544
SAR 599 total
includes taxes & fees
21 Nov - 22 Nov
Room-sofa Bed Stay Rooftop Pool & Gym, A

Casa Quijano 06 By Wynwood House

4.0 star property
Santa Ana
9.0 out of 10, Wonderful, (4)
"Easy to find, seamless check-in "
Canada
Matthew
The price is SAR 310
SAR 464 total
includes taxes & fees
15 Dec - 16 Dec
Casa Quijano 06 By Wynwood House

Crowne Plaza Panama Airport by IHG

4.0 star property
21.1 km from Santa Ana
8.4 out of 10, Very Good, (2274)
"Spacious room, clean, good breakfast "
United States
Juan
The price is SAR 413
SAR 454 total
includes taxes & fees
26 Nov - 27 Nov
Crowne Plaza Panama Airport by IHG

Central Hotel Panama Casco Viejo

4.0 star property
San Felipe, 0.9 km from Santa Ana
9.0 out of 10, Wonderful, (1002)
"Hotel was beautiful, staff was very helpful and accommodating. We had the pool two separate days to ourselves. Breakfadt was very good. Staff was very helpful getting us drivers wherever we wanted to go in the city."
United States
MICHELE
Central Hotel Panama Casco Viejo

Hotel Coral Suites

3.5 star property
El Cangrejo, 3.7 km from Santa Ana
9.0 out of 10, Wonderful, (1002)
"Great place for the price. "
United States
Ryan
The price is SAR 260
SAR 286 total
includes taxes & fees
21 Nov - 22 Nov
Hotel Coral Suites

La Concordia Boutique Hotel

4.0 star property
San Felipe, 0.5 km from Santa Ana
9.6 out of 10, Exceptional, (192)
"The staff was very friendly and supportive. The room was spectacular! It was beautifully decorated and very clean. It was just a delight to stay in this lovely hotel!"
United States
Madelaine
La Concordia Boutique Hotel

Waldorf Astoria Panama

5.0 star property
Bella Vista, 2.9 km from Santa Ana
9.0 out of 10, Wonderful, (1003)
"Very beautiful room was spotless, and staff was very good with customer service"
United States
Anthony
The price is SAR 643
SAR 707 total
includes taxes & fees
1 Dec - 2 Dec
Waldorf Astoria Panama

Principe Hotel and Suites

3.0 star property
El Cangrejo, 3.9 km from Santa Ana
9.0 out of 10, Wonderful, (1555)
"Clean from affordable pleasant staff was very nice stay "
United States
Iris
The price is SAR 191
SAR 210 total
includes taxes & fees
23 Nov - 24 Nov
Principe Hotel and Suites

Megapolis Hotel Panamá

4.5 star property
Punta Paitilla, 3.5 km from Santa Ana
8.4 out of 10, Very Good, (1214)
"Great stay "
United States
Mark
Megapolis Hotel Panamá

Hotel Riu Plaza Panama

5.0 star property
Campo Alegre, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (4543)
"Great place to stay "
United States
yohosy
The price is SAR 445
SAR 489 total
includes taxes & fees
23 Nov - 24 Nov
Hotel Riu Plaza Panama

Hospedium Princess Hotel Panama

3.5 star property
Obarrio, 3.6 km from Santa Ana
7.6 out of 10, Good, (676)
"The breakfast was great, I love the pool."
United States
Estefani
The price is SAR 208
SAR 229 total
includes taxes & fees
21 Nov - 22 Nov
Hospedium Princess Hotel Panama

TRYP by Wyndham Panamá Centro

3.5 star property
El Cangrejo, 3.5 km from Santa Ana
9.2 out of 10, Wonderful, (1009)
"Staff was helpful, room was clean and I enjoyed my stay. "
United States
Lystra
The price is SAR 289
SAR 318 total
includes taxes & fees
15 Dec - 16 Dec
TRYP by Wyndham Panamá Centro

Plaza Paitilla Inn Hotel

3.5 star property
Punta Paitilla, 3.4 km from Santa Ana
9.4 out of 10, Exceptional, (2135)
"Very nice hotel, all amenities met our needs. "
Canada
gordon
The price is SAR 385
SAR 423 total
includes taxes & fees
3 Dec - 4 Dec
Plaza Paitilla Inn Hotel

Novotel Panama City

4.0 star property
El Cangrejo, 4.3 km from Santa Ana
9.2 out of 10, Wonderful, (1006)
"Room very clean, nice staffs and good location "
United States
Hayden
The price is SAR 341
SAR 375 total
includes taxes & fees
9 Dec - 10 Dec
Novotel Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
Juan Diaz, 12.7 km from Santa Ana
9.6 out of 10, Exceptional, (629)
"Beautiful property. Excellent lunch, fish tacos were amazing. "
United States
Marc
The price is SAR 813
SAR 894 total
includes taxes & fees
22 Nov - 23 Nov
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santa Ana with a pool

Top guest rated hotels in Santa Ana

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

If you're spending some time in San Felipe, Interoceanic Canal Museum and National Theater are top sights worth seeing.

Top Santa Ana Hotel Reviews

Find out more about Santa Ana

Top reasons to visit Santa Ana

  • Cultural Attractions: Visit historical sites like the Church of Santa Ana and Plaza Santa Ana, rich in local culture and history.
  • Shopping Opportunities: Explore popular shopping malls and centers, perfect for shopping enthusiasts.
  • Vibrant Nightlife: Experience the local nightlife with engaging activities like bar crawls.
  • Outdoor Adventures: Enjoy outdoor activities in scenic areas, ideal for families and travelers alike.
  • Diverse Accommodations: Choose from a variety of hotels and apartments tailored to different traveler needs.

Find great hotels near Santa Ana

Discover the perfect blend of comfort and style in Santa Ana, Panama City, with a variety of hotel accommodations tailored to meet diverse traveler needs. Whether you're seeking a pet-friendly stay or a business travel experience, you'll find a range of options, including hotels and apartments. Explore popular choices like Hotel El Panama and enjoy the vibrant atmosphere of this charming neighborhood.

  • Central Hotel Panama Casco Viejo: Experience the charm of Panama City at Central Hotel Panama Casco Viejo, a 4-star hotel that blends urban sophistication with a relaxing spa escape. Located only 805m from Santa Ana, this hotel caters to travelers seeking a rejuvenating getaway. Unwind at the full-service spa offering a range of treatments, including facials, manicures, and body scrubs. The property’s city center location makes it an ideal base for exploring local attractions while enjoying the comfort of spacious accommodations and excellent pool service.
  • American Trade Hotel: Discover romance and family-friendly amenities at the 4.5-star American Trade Hotel, situated just 644m from Santa Ana. This elegant hotel is perfect for couples and families alike, featuring a variety of children’s services and romantic packages. Guests can enjoy meals with stunning garden views at the on-site restaurant, as well as special amenities like in-room massages and outdoor pool loungers. The property’s inviting atmosphere makes it a great choice for creating cherished memories with loved ones in a luxurious setting.
  • Sofitel Legend Casco Viejo, Panama City: Immerse yourself in luxury at the 5-star Sofitel Legend Casco Viejo, Panama City, located 1.1km from Santa Ana. This eco-certified hotel is designed for discerning travelers who appreciate sustainability without sacrificing comfort. With its high-end amenities and business-friendly services, guests can enjoy a seamless blend of work and relaxation. The elegant accommodations and commitment to eco-friendly practices make this hotel a top choice for those seeking an upscale, environmentally conscious stay in the heart of Panama City.

Where to stay near Santa Ana

Discover the vibrant atmosphere of Santa Ana, a charming neighborhood in Panama City, where you can enjoy a blend of family-friendly activities and business opportunities. Explore the rich culture of Panama, indulge in local cuisine, and experience the warm hospitality of the friendly locals. Nearby attractions offer a relaxing escape, while the city's luxury amenities ensure a comfortable stay. Santa Ana provides the perfect base for your Panamanian adventure.

  • Panama City: As the vibrant capital of Panama, Panama City is a bustling metropolis where modern skyscrapers meet historic districts. Located in close proximity to Santa Ana, this city offers an array of experiences for travelers. The number of visitors remains relatively steady year-round, with peaks in January, July, and September. Here, you can engage in family-friendly activities, explore city-themed attractions, or attend business ventures. Don't miss the shopping centers and malls, which are perfect for some retail therapy, while local landmarks like parks and beaches provide a serene escape amidst the urban hustle.
  • Casco Viejo: Just 644m from Santa Ana, Casco Viejo is a charming neighborhood rich in history and culture. Known for its well-preserved colonial architecture and vibrant streets, this area draws travelers year-round, especially in January and during the spring months of March and April. Visitors can enjoy family outings or engage in city-themed explorations. This neighborhood is packed with shopping areas and resorts, and features captivating landmarks such as parks and beaches, making it an ideal spot for relaxation and leisure.
  • San Felipe: Also located 644m from Santa Ana, San Felipe is a lively neighborhood that showcases a blend of historical significance and modern flair. It attracts visitors consistently, with peak times in February to March and December. San Felipe is perfect for families seeking fun, business travelers looking for convenience, or anyone interested in city experiences. The area is surrounded by shopping venues and resorts, while local attractions include beautiful parks, beaches, and historic sites, providing a delightful mix of activities for every visitor.

Things to do near Santa Ana

Santa Ana in Panama City is perfect for family and business vacations, offering a variety of activities. Visitors can explore popular shopping malls and centers, making it an ideal spot for shopping enthusiasts. Additionally, engaging activities in Panama City, like a fun bar crawl, provide a taste of the local nightlife. Whether you're looking to shop or enjoy vibrant entertainment, Santa Ana has something for everyone.

Shopping

For a delightful shopping experience in Santa Ana, visit the Albrook Shopping Mall, just 1.6km away, offering a vibrant mix of business and entertainment. Nearby, Avenida Central, 483m away, features family-friendly shops, while Uruguay Street, 3.2km away, is perfect for local finds.

Recreation

Experience the energetic atmosphere at Maracana Stadium, located 1.3km from Santa Ana, where you can watch thrilling sports events. For a more extensive experience, check out Estadio Rommel Fernandez and Estadio Nacional Rod Carew, both offering vibrant sports vibes just a short drive away.

Adventure

Embark on the Honeycreeper Ridge Trail, located 43.5km from Santa Ana, where you can hike through lush scenery and experience the thrill of nature. For an adrenaline rush, visit Gatun Eco Adventures, 48.3km away, to soar through the trees on an exciting zipline ropes course.

Nightlife

In Santa Ana, the National Theater offers captivating performances just 966m away, while the Anita Villalaz Theater, located 1.3km away, presents a rich cultural experience. The nearby Amador Theater, only 483m away, adds to the vibrant nightlife with its romantic and entertaining atmosphere.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Ana

To save money on your trip to Santa Ana, consider visiting between September and November, when accommodation prices are lower. Tuesdays are the most affordable days to stay, while Saturdays tend to be pricier. Utilize Expedia's search tool to filter options based on your budget and preferences, and don't forget to check for coupon deals. Combining your hotel, flights, and activities into a package deal can lead to additional savings. Lastly, explore the area on foot to minimize transportation costs and enjoy free activities.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Santa Ana are September to November, where the prices are slightly lower. This is in comparison to January and March to April, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Santa Ana is Tuesday. The most expensive day to stay around Santa Ana is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia's search tool to refine your preferences, such as your budget, preferred location, and the type of hotel you’re looking for. To find the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel stay in Santa Ana with your flights and activities through an Expedia package deal.

Find the best attractions near Santa Ana

Santa Ana, located in Panama City, offers a delightful mix of cultural and scenic experiences perfect for families and business travelers alike. Explore notable attractions such as the Panama Canal, the Church of Santa Ana, Plaza Santa Ana, San Sebastián, and Santa Ana Park. This vibrant area is steeped in history, making it an ideal destination for those seeking outdoor adventures and rich cultural experiences.

  • Metropolitan Cathedral of Panama: This stunning cathedral, located 805m from Santa Ana, captivates visitors with its rich cultural heritage and beautiful architecture. Marvel at its intricate designs and learn about Panama's religious history as you explore this iconic landmark.
  • Interoceanic Canal Museum: Situated 805m away, this museum offers an engaging look into the fascinating history of the Panama Canal. Discover interactive exhibits and artifacts that showcase the canal's impact on global trade and Panama's development.
  • Ancon Hill: Just 966m from Santa Ana, Ancon Hill provides breathtaking panoramic views of the city and surrounding landscape. Enjoy outdoor activities, hike its trails, and immerse yourself in the stunning natural scenery.

Best time to go to Santa Ana

The best time to visit Santa Ana is dependent on what kind of holiday you are seeking. April is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. November is its coolest month on average. At this time, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.8°F (26.0°C)No RainMostly SunnyAverageSlightly High
February79.2°F (26.2°C)No RainMostly SunnySlightly HighAverage
March79.7°F (26.5°C)No RainMostly SunnySlightly HighSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageSlightly High
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudySlightly LowAverage
July79.3°F (26.3°C)Frequent RainMostly CloudyAverageAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly LowSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudyAverageSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly HighAverage

The nearest major airports for your trip to Santa Ana

When visiting Santa Ana, Panama, you have access to several major airports. Panama City (PTY-Tocumen Intl.) is located 20.9km away, with notable hotels such as The Santa Maria, A Luxury Collection Hotel, 8.0km from the airport, and JW Marriott Panama, 16.1km away. Alternatively, Panama City (PAC-Marcos A. Gelabert Intl.) is only 3.2km from Santa Ana, with top hotels like Sofitel Legend Casco Viejo, 3.2km away, and Waldorf Astoria Panama, also 3.2km away. Lastly, Rio Hato (RIH-Scarlett Martinez Intl.) is 91.7km away, featuring hotels like The Buenaventura Golf & Beach Resort, 6.4km from the airport. Transportation services are available at each hotel for convenient airport access.

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Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Cinta Costera and Avenida Balboa while you're in the neighborhood.
Where is the best hotel for a stay in Santa Ana?
Based on Expedia customer reviews, Hotel República is the highest ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi. Another top choice in the area is Hostal La Cigarra.
How many hotels can I expect to find in Santa Ana?
Expedia has 96 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.
What is there to do in this Panama City neighborhood?
If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighborhood. Albrook Shopping Mall, Amador Theater, and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.