Photo by Isa
Find all hotels by Independent in Santa Ana from SAR 101
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check prices for these dates
Tonight
Tomorrow
This weekend
Next weekend
Compare rooms and suites by Independent in Santa Ana with rates, reviews, and availability. Most hotels are fully refundable.

Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
9.4 out of 10, Exceptional, (2032)
The price is SAR 413
SAR 454 total
includes taxes & fees
9 Jun - 10 Jun

Principe Hotel and Suites
Principe Hotel and Suites
8.8 out of 10, Excellent, (1335)
The price is SAR 219
SAR 241 total
includes taxes & fees
3 Jun - 4 Jun

Hotel Ojos del Rio
Hotel Ojos del Rio
8.2 out of 10, Very Good, (788)
The price is SAR 173
SAR 192 total
includes taxes & fees
10 Jun - 11 Jun

Las Americas Golden Tower Panama
Las Americas Golden Tower Panama
8.8 out of 10, Excellent, (1006)
The price is SAR 508
SAR 559 total
includes taxes & fees
1 Jun - 2 Jun

Studio Coliving
Studio Coliving
8.0 out of 10, Very Good, (362)
The price is SAR 144
SAR 160 total
includes taxes & fees
2 Jun - 3 Jun

Megapolis Hotel Panamá
Megapolis Hotel Panamá
8.4 out of 10, Very Good, (902)
The price is SAR 476
SAR 524 total
includes taxes & fees
29 Jun - 30 Jun

Decapolis Hotel Panama City
Decapolis Hotel Panama City
8.6 out of 10, Excellent, (1192)
The price is SAR 354
SAR 389 total
includes taxes & fees
11 Jun - 12 Jun

The Executive Hotel
The Executive Hotel
9.2 out of 10, Wonderful, (1000)
The price is SAR 376
SAR 414 total
includes taxes & fees
7 Jun - 8 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Recent reviews of Santa Ana hotels
Recent reviews of Santa Ana hotels

Ramada Plaza By Wyndham Panama Punta Pacífica
5/5 Excellent
"This hotel provided an absolutely wonderful experience. Excellent location, pristine rooms, friendly, welcoming & accommodating staff who went above and beyond, reasonable rate, vegetarian friendly breakfast. Zero complaints. Will definitely stay again and recommend to others!"
A verified traveler stayed at Ramada Plaza By Wyndham Panama Punta Pacífica
Posted 6 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in Santa Ana Neighborhoods
Hotels near popular Panama City Attractions
More Hotel Options in Santa Ana
More Accommodation Types in Santa Ana
Explore more hotels
- Ramada Plaza By Wyndham Panama Punta Pacífica
- Waldorf Astoria Panama
- Novotel Panama City
- Principe Hotel and Suites
- TRYP by Wyndham Panamá Centro
- Central Hotel Panama Casco Viejo
- Las Americas Golden Tower Panama
- Hospedium Princess Hotel Panama
- Riande Aeropuerto Hotel & Casino
- Hotel Ojos del Rio
- Marriott Panama Hotel
- Sheraton Grand Panama
- Decapolis Hotel Panama City
- Studio Coliving
- W Panama
- The Executive Hotel
- Waymore Hotel Spa & Casino
- Sofitel Legend Casco Viejo, Panama City
- Bristol Panama, a Registry Collection Hotel
- Holiday Inn Panama Distrito Financiero by IHG