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Our top choices for Defiance hotels

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
8.0 out of 10, Very Good, (1,211 reviews)
"Everything was great for overnight stay. "
United States
Regina
The price is SAR 335
SAR 387 total
includes taxes & fees
19 Apr - 20 Apr
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Baymont by Wyndham Warrenton

Baymont by Wyndham Warrenton
2.5 star property
Warrenton
7.6 out of 10, Good, (1,002 reviews)
"The front desk stuff were nice and welcoming. The room was clean and the breakfast was great. "
United States
Dan
The price is SAR 277
SAR 317 total
includes taxes & fees
19 Apr - 20 Apr
Baymont by Wyndham Warrenton

Quality Inn Foristell

Quality Inn Foristell
2.5 star property
Foristell
8.2 out of 10, Very Good, (967 reviews)
"Staff was great, breakfast good and the room was clean and comfortable!!!"
United States
Chris
The price is SAR 328
SAR 371 total
includes taxes & fees
28 Apr - 29 Apr
Quality Inn Foristell

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
Fenton
7.8 out of 10, Good, (1,189 reviews)
"Great location, comfy and clean rooms "
United States
Nestor
The price is SAR 319
SAR 368 total
includes taxes & fees
19 Apr - 20 Apr
Wingate by Wyndham St. Louis/Fenton Route 66

Super 8 by Wyndham Warrenton

Super 8 by Wyndham Warrenton
2.0 star property
Warrenton
7.4 out of 10, Good, (640 reviews)
"The parking was easy, the room was verry clean."
United States
Gary
The price is SAR 198
SAR 226 total
includes taxes & fees
23 Apr - 24 Apr
Super 8 by Wyndham Warrenton

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1,001 reviews)
"This was one of our best stays ever nice hot breakfast. Clean room nice staff will stay again "
United States
Lavania
The price is SAR 308
SAR 363 total
includes taxes & fees
19 Apr - 20 Apr
Sleep Inn & Suites O'Fallon MO - Technology Drive

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
St. Peters
9.4 out of 10, Exceptional, (1,000 reviews)
"Great stay! Very clean and staff was very nice. Definitely will be staying there on my return visit to the area!"
United States
Roxanne
The price is SAR 413
SAR 474 total
includes taxes & fees
10 May - 11 May
Drury Inn & Suites St. Louis St. Peters

WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
St. Peters
8.8 out of 10, Excellent, (83 reviews)
"Nice hotel with good staff."
United States
Michael
The price is SAR 324
SAR 384 total
includes taxes & fees
22 Apr - 23 Apr
WoodSpring Suites St Peters-OFallon

Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
O'Fallon
8.6 out of 10, Excellent, (908 reviews)
"It was a wonderful stay for my girls and her birthday. She had a blast and the room was Lovely 😍🌹"
United States
Amanda
The price is SAR 379
SAR 447 total
includes taxes & fees
19 Apr - 20 Apr
Holiday Inn Express St. Louis West - O'Fallon by IHG

Hampton Inn St. Louis Wentzville

Hampton Inn St. Louis Wentzville
2.5 star property
Wentzville
9.0 out of 10, Wonderful, (692 reviews)
"Very pet friendly. "
United States
Sara
The price is SAR 477
SAR 546 total
includes taxes & fees
27 Apr - 28 Apr
Hampton Inn St. Louis Wentzville

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very Good, (1,000 reviews)
"The breakfast was good. They had two different waffle choices every day. "
United States
Josephine
The price is SAR 351
SAR 404 total
includes taxes & fees
3 May - 4 May
Comfort Suites St Charles - St Louis

Fairfield Inn & Suites Wentzville

Fairfield Inn & Suites Wentzville
3.0 star property
Wentzville
9.0 out of 10, Wonderful, (670 reviews)
"Property was nice, easy check-in, nice breakfast, room was clean."
United States
Doris
The price is SAR 480
SAR 549 total
includes taxes & fees
27 Apr - 28 Apr
Fairfield Inn & Suites Wentzville

Quality Inn Near Six Flags St. Louis

Quality Inn Near Six Flags St. Louis
2.5 star property
Pacific
8.4 out of 10, Very Good, (370 reviews)
"Breakfast menu is extremely limited. Breakfast does not have bread/ butter."
United States
Arinjay
The price is SAR 409
SAR 468 total
includes taxes & fees
3 May - 4 May
Quality Inn Near Six Flags St. Louis

Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
2.5 star property
Washington
9.2 out of 10, Wonderful, (673 reviews)
"Great stay and accommodations. The pool was very nice. "
United States
Shane
The price is SAR 484
SAR 551 total
includes taxes & fees
19 Apr - 20 Apr
Best Western Plus Washington Hotel

Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
St. Charles
8.0 out of 10, Very Good, (1,000 reviews)
"Hotel was clean. Located in a good area, would stay here again. "
United States
Christy
The price is SAR 348
SAR 399 total
includes taxes & fees
22 Apr - 23 Apr
Super 8 by Wyndham St Charles

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very Good, (1,001 reviews)
"Everything was great as always at this location as i have stayed here many times"
United States
Gregory
The price is SAR 428
SAR 491 total
includes taxes & fees
17 May - 18 May
Hampton Inn St. Charles St. Peters

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
Valley Park
9.6 out of 10, Exceptional, (1,016 reviews)
"Very clean place with great food and friendly staff. "
Canada
Kara
The price is SAR 416
SAR 487 total
includes taxes & fees
10 May - 11 May
Drury Inn & Suites Southwest St. Louis

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
St. Charles
9.6 out of 10, Exceptional, (1,001 reviews)
"Clean rooms, friendly staff, great breakfast and kickback dinner."
United States
Amy
The price is SAR 495
SAR 574 total
includes taxes & fees
3 May - 4 May
Drury Plaza Hotel St. Louis St. Charles

Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
Wentzville
9.4 out of 10, Exceptional, (895 reviews)
"Great location, clean, modern, killer shower and good bed! I would definitely recommend!"
United States
John
The price is SAR 506
SAR 604 total
includes taxes & fees
19 Apr - 20 Apr
Holiday Inn Express & Suites Wentzville St Louis West by IHG

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1,626 reviews)
"Staff was wonderful, location is great for our needs, and it was a quiet stay-which we loved. "
United States
Jessica
The price is SAR 331
SAR 385 total
includes taxes & fees
4 May - 5 May
The Wildwood Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighboring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Top Defiance Hotel Reviews

More cheap stays in Defiance

Find out more about Defiance

Top reasons to visit Defiance

  • Outdoor Adventures: Defiance offers scenic hiking trails and beautiful recreational areas perfect for nature lovers and outdoor enthusiasts.
  • Charming Downtown: Stroll through downtown Defiance to enjoy local entertainment, friendly faces, and leisurely walks.
  • Romantic Getaways: The area's picturesque landscape and tranquil parks make it ideal for couples seeking a romantic escape.
  • Family Fun: Enjoy various attractions, including urban parks and amusement parks, perfect for family-friendly outings.
  • Diverse Accommodations: Defiance features a range of lodging options, including pet-friendly and LGBTQIA-welcoming places to stay.

Find great hotels near Defiance

Explore a variety of lodging options in Defiance, Missouri, where you'll find everything from comfortable hotels to inviting apartments. This charming destination caters to business travelers and vacationers alike, offering pet-friendly accommodations and an LGBTQIA-welcoming atmosphere. Whether you're searching for top hotels or simply seeking a cozy place to stay, Defiance has something for everyone to enjoy during your visit.

  • Sonesta ES Suites St. Louis - Chesterfield: This 3-star hotel is an ideal choice for pet lovers seeking a comfortable getaway. Located 19.3km from Defiance, Sonesta ES Suites St. Louis offers a welcoming environment for both travelers and their furry companions. The hotel features pet-friendly amenities, including food and water bowls, ensuring a hassle-free experience for you and your dog. With spacious suites that provide all the comforts of home, this hotel is perfect for those who prioritize both relaxation and convenience during their stay.
  • The Wildwood Hotel: Embrace the great outdoors with The Wildwood Hotel, a 3.5-star establishment located 14.5km from Defiance. This nature-themed hotel is perfect for business travelers and ski enthusiasts alike, offering easy access to nearby ski lifts and shuttles. Guests can enjoy beautifully designed rooms that reflect the surrounding natural beauty, making it a serene retreat. The hotel also provides facilities tailored for business needs, ensuring that you can balance work with leisure seamlessly.
  • Hyatt Place St. Louis/Chesterfield: Situated 19.3km from Defiance, the 3-star Hyatt Place St. Louis/Chesterfield caters to families and business travelers alike. This hotel is pet-friendly, allowing you to bring your dog along for the adventure. With amenities specifically designed for children and a welcoming atmosphere, families can enjoy a stress-free stay. The hotel offers modern rooms with ample space, as well as a variety of services to ensure your stay is both comfortable and productive.

Where to stay near Defiance

Defiance, Missouri, offers a delightful blend of outdoor adventure and charming historical vibes perfect for a romantic getaway or family-friendly fun. Stroll through downtown Defiance, where you can enjoy leisurely walks, local entertainment, and friendly faces. Take a relaxing break at nearby parks or explore the beautiful countryside, making the most of your vacation in this inviting community. Whether you seek adventure or tranquility, Defiance has something special in store for every traveler.

  • Chesterfield: Located 19.3km from Defiance, Chesterfield is a vibrant city known for its family-friendly atmosphere and entertainment options. Visitors flock here primarily in April and during the summer months, drawn to its lively theater scene, exciting arcade adventure zone, and music concerts. Notable attractions include a theme park and a sports facility stadium, making it an ideal destination for those seeking a mix of thrilling activities and communal experiences.
  • Saint Albans: Just 6.4km from Defiance, Saint Albans offers a charming escape with a focus on outdoor adventures and family fun. This city sees peak visitor numbers in the spring and summer months, making it a popular choice for those looking to enjoy an amusement park, arcade adventure zone, and recreational areas. Local highlights include a spacious urban park and a picturesque lake, perfect for outdoor enthusiasts and families seeking memorable experiences together.
  • Augusta: Situated 11.3km away from Defiance, Augusta is a delightful city that attracts visitors with its romantic ambiance and outdoor recreation. The peak travel months are May, July, and September, when tourists take advantage of the scenic hiking trails and recreational areas. Augusta is also home to a vibrant event conference venue and a beautiful lake, providing plenty of opportunities for relaxation and exploration in a picturesque setting.

Things to do in and around Defiance

Defiance, Missouri, is a charming destination perfect for outdoor enthusiasts and couples seeking a romantic getaway. Enjoy scenic hiking trails and access to beautiful recreational areas that promise a memorable stay. Whether you’re exploring the lush landscape or simply relaxing in nature, Defiance offers a range of outdoor activities that will make your vacation truly special.

Shopping

In Defiance, you can shop at St. Louis Premium Outlets, just 11.3km away, offering a mix of entertainment and family-friendly vibes. If you're up for a drive, visit Taubman Prestige Outlets, located 16.1km away, for more shopping options.

Recreation

Explore Broemmelsiek Park for serene nature walks and peaceful picnic spots that promote relaxation. Enjoy live music and vibrant entertainment at The Factory, only 16.1km away. For golf enthusiasts, the Missouri Bluffs Golf Course, 11.3km from Defiance, offers a beautiful outdoor setting for a rewarding game.

Adventure

At Hidden Valley Ski Resort, 14.5km from Defiance, experience thrilling skiing and snowboarding in a vibrant winter atmosphere. Hurricane Harbor, located 16.1km away, offers exciting water rides and family-friendly adventures. For a scenic hike, explore Matson Hill Park Trailhead right in Defiance, surrounded by beautiful outdoor views.

Nightlife

Experience the vibrant nightlife in Defiance with a visit to Chesterfield Sports Fusion, an exciting arcade adventure zone just 14.5km away. For a touch of romance and culture, check out the New Jewish Theatre, 32.2km from Defiance. Don't miss the exhilarating Sky Zone Indoor Trampoline Park, located 16.1km away.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Defiance

For budget-conscious travelers visiting Defiance, Missouri, plan your trip between December and February for lower accommodation rates, with Mondays being the cheapest days to stay. Utilize Expedia to compare hotel options, and consider package deals that combine flights and activities for added savings. Look for minute deals and beverage discounts to stretch your budget further. Additionally, explore free local activities and attractions to enhance your experience without breaking the bank.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Defiance are December to February, where the prices are slightly lower. This is in comparison to May to July, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Defiance is Monday. The most expensive day to stay in Defiance is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia's search tool to customize your options based on your budget, desired location, and preferred hotel type. To find the best prices and deals, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel reservations in Defiance with your flights and activities through an Expedia package deal.

Find the best attractions in and around Defiance

Defiance, Missouri, is an excellent destination for outdoor, romantic, and entertainment-themed vacations. Visitors can enjoy a variety of attractions, including urban parks, state parks, and amusement parks. The area's points of interest cater to travelers seeking outdoor adventures, family fun, and a vibrant city experience, making it a perfect spot for a memorable getaway.

  • Six Flags St. Louis: Experience thrilling rides and family-friendly attractions at this exciting amusement park located 16.1km from Defiance. With its adventurous atmosphere and outdoor fun, Six Flags St. Louis is perfect for those seeking a day of excitement and entertainment.
  • August A. Busch Memorial Conservation Area: Nestled within Defiance, this beautiful reserve offers a serene escape into nature. Enjoy family-friendly excursions and connect with friendly locals as you explore hiking trails, wildlife, and scenic views that showcase the area's natural beauty.
  • Historic Daniel Boone Home and Heritage Center: Delve into the rich culture and history of Missouri at this historic house in Defiance. Discover the life of frontiersman Daniel Boone through engaging exhibits and guided tours that highlight the significance of this landmark.

Best time to go to Defiance

The best time to visit Defiance can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Defiance falls in July, when visitor numbers are moderately high and weather is mostly sunny with light rain. The coolest average temperature in Defiance falls in January, visitor numbers are moderately low and weather is mostly cloudy with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January31.6°F (-0.2°C)Light RainMostly CloudyModerately LowSlightly Low
February34.7°F (1.5°C)Light RainMostly SunnyAverageSlightly Low
March46.4°F (8.0°C)Light RainMostly SunnyAverageAverage
April55.9°F (13.3°C)Light RainMostly SunnyModerately HighAverage
May66.2°F (19.0°C)Light RainMostly SunnyAverageSlightly High
June75.9°F (24.4°C)Light RainMostly SunnyAverageSlightly High
July79.0°F (26.1°C)Light RainMostly SunnyModerately HighSlightly High
August77.2°F (25.1°C)Light RainMostly SunnyAverageAverage
September70.9°F (21.6°C)Light RainMostly SunnyModerately HighAverage
October58.5°F (14.7°C)Light RainMostly SunnyAverageAverage
November46.2°F (7.9°C)Light RainMostly SunnyModerately LowAverage
December37.6°F (3.1°C)Light RainMostly SunnyModerately LowSlightly Low

The nearest major airports for your trip to Defiance

Traveling to Defiance, Missouri, is convenient with nearby airports offering various accommodation options. St. Louis Lambert International Airport (STL) is situated 37.0km from Defiance, with excellent hotels such as The Ritz-Carlton, St. Louis, and Ameristar Casino Resort and Spa, both about 11.3km away. Another option is Spirit of St. Louis Airport (SUS), located 11.3km from Defiance, providing access to hotels like DoubleTree by Hilton Hotel St. Louis - Chesterfield, just 6.4km away. Both airports ensure easy transportation for visitors, making your stay in Defiance enjoyable and hassle-free.

Frequently asked questions

What's the best place to stay in Defiance?
Hollywood Casino & Hotel St. Louis, located 18.1 mi (29.2 km) from the heart of Defiance, is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham and The Wildwood Hotel. See all available top hotels, or vacation rentals in Defiance.
What's the top vacation rental in Defiance?
St. Charles 1860's Gem - Sleeps 6!: Visitors like this Defiance vacation home rental. It is located on a river and has a garden, a selection of books, and air-conditioning to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
Where can I learn more about changing or cancelling my trip to Defiance?
For more information about changing or cancelling your trip to Defiance, head over to our customer service page.
Where is the best hotel to stay with easy access to August A. Busch Memorial Conservation Area?
Sleep Inn & Suites O'Fallon MO - Technology Drive is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 2.6 mi (4.3 km) from August A. Busch Memorial Conservation Area. Other good options within a few miles include Hilton Garden Inn St. Louis/O'Fallon MO and Holiday Inn Express St. Louis West - O'Fallon, an IHG Hotel.
What about the best place to stay near Chandler Hill Vineyards?
One of the top choices for your stay is The Wildwood Hotel, located 10 mi (16.1 km) from Chandler Hill Vineyards, and this 3.5-star hotel offers free breakfast and an indoor pool.
What are some accommodations with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Offers an indoor pool, an outdoor pool, and buffet. The Wildwood Hotel and Ameristar Casino Resort and Spa are two additional hotels that offer an onsite pool. View all hotels with pools in Defiance.
What's the best place to stay near Lambert-St. Louis International Airport (STL)?
Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.
What's it like to stay in Defiance?
Visitors can enjoy all that Defiance has to offer including the wineries and parks. Top sights in the area include St. Louis Union Station, Enterprise Center, and Busch Stadium. In Defiance, there are 19 hotels and other accommodations to choose from. Find out more about Defiance.
What is there to see in Defiance?
Natural beauty is on display at Matson Hill Park Trailhead, August A. Busch Memorial Conservation Area, and Missouri River. A couple of additional sights to add to your agenda are Chandler Hill Vineyards and Sugar Creek Winery. Check out what more to see and do in Expedia's Defiance guide.
What's the seasonal weather like in Defiance?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.