Find 2 Star Hotels in Defiance, MO from SAR 236
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Defiance 2 Star Hotels
Compare Defiance 2 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Best Western Plus St. Louis West-Westport
Best Western Plus St. Louis West-Westport
8.0 out of 10, Very Good, (1002)
The price is SAR 368
SAR 426 total
includes taxes & fees
14 Jul - 15 Jul

Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
4.6 out of 10, (1002)
The price is SAR 249
SAR 288 total
includes taxes & fees
20 Jul - 21 Jul

Relax Inn Saint Charles
Relax Inn Saint Charles
6.4 out of 10, (904)
The price is SAR 236
SAR 272 total
includes taxes & fees
29 Jun - 30 Jun

Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. Peters
8.0 out of 10, Very Good, (1002)
The price is SAR 387
SAR 445 total
includes taxes & fees
6 Jul - 7 Jul

Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology Drive
8.8 out of 10, Excellent, (1002)
The price is SAR 368
SAR 434 total
includes taxes & fees
6 Jul - 7 Jul

Motel 6 Maryland Heights, MO
Motel 6 Maryland Heights, MO
6.0 out of 10, (1001)
The price is SAR 244
SAR 283 total
includes taxes & fees
6 Jul - 7 Jul

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
9.2 out of 10, Wonderful, (892)
The price is SAR 443
SAR 515 total
includes taxes & fees
27 Jul - 28 Jul

Country Inn & Suites by Radisson, St. Peters, MO
Country Inn & Suites by Radisson, St. Peters, MO
8.2 out of 10, Very Good, (1005)
The price is SAR 390
SAR 448 total
includes taxes & fees
30 Jun - 1 Jul
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 3-star hotels
Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Defiance.

Hollywood Casino & Hotel St. Louis
777 Casino Center Drive, Maryland Heights, MO
8.2/10 Very Good! (1,945 reviews)
Still don't see what you're looking for?
See all properties in Defiance.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Defiance
Trip time! Discover the wineries, parks, and history in Defiance.

Explore a world of travel with Expedia
Explore a world of travel with Expedia
Defiance Hotels by Star Rating
Stay near popular Defiance attractions
- Hotels near Chandler Hill Vineyards
- Hotels near August A. Busch Memorial Conservation Area
- Hotels near Historic Daniel Boone Home and Heritage Center
- Hotels near Sugar Creek Winery
- Hotels near Yellow Farmhouse Winery
- Hotels near Broemmelsiek Park
- Hotels near Six Flags St. Louis
- Hotels near Hollywood Casino Amphitheatre
- Hotels near Mississippi River
- Hotels near Westport Plaza
- Hotels near Ameristar Casino St. Charles
- Hotels near Hollywood Casino
- Hotels near St Charles Convention Center
- Hotels near Magic House - St. Louis Children's Museum
- Hotels near Purina Farms
- Hotels near Lindenwood University
- Hotels near Route 66 State Park
- Hotels near Missouri River
- Hotels near Historic Main Street
- Hotels near Family Arena
More Accommodation Types in
- Vacation Homes in Defiance
- Chalets in Defiance
- Apartments in Defiance
- Condo Rentals in Defiance
- Cottages in Defiance
- Cabin Rentals in Defiance
- B&B in Defiance
- Motels in Defiance
- Aparthotels in Defiance
- Villas in Defiance
- Lodges in Defiance
- Guest Houses in Defiance
- Hostels in Defiance
- Inns in Defiance
Explore more hotels
- Elimwood Hotel, A Ramada by Wyndham
- Courtyard by Marriott St Louis Creve Coeur
- Holiday Inn St. Louis West Six Flags by IHG
- Courtyard by Marriott St Louis Westport Plaza
- Crowne Plaza St. Louis Airport by IHG
- Country Inn & Suites by Radisson, St. Peters, MO
- Drury Plaza Hotel St. Louis Chesterfield
- Comfort Inn St. Louis - Westport Event Center
- Hyatt Place St. Louis/Chesterfield
- Relax Inn Saint Charles
- Best Western Plus The Charles Hotel
- Comfort Suites St Charles - St Louis
- Motel 6 Maryland Heights, MO
- Drury Plaza Hotel St. Louis St. Charles
- Sleep Inn & Suites O'Fallon MO - Technology Drive
- Hilton St. Louis Frontenac
- Hampton Inn St. Charles St. Peters
- Country Inn & Suites by Radisson, St. Charles Historic District
- Drury Inn & Suites St. Louis St. Peters
- Comfort Inn & Suites St. Louis - O'Fallon