Find 4 Star Hotels in Defiance, MO from SAR 475

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Check availability on Defiance 4 Star Hotels

Compare Defiance 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Defiance 4-star hotels

Ameristar Casino Resort and Spa
6 restaurants, breakfast served

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very Good, (1002)
"Loved my stay here will be back "
The price is SAR 635
SAR 804 total
includes taxes & fees
24 Aug - 25 Aug
Ameristar Casino Resort and Spa
DoubleTree by Hilton St. Louis - Westport
Interior

DoubleTree by Hilton St. Louis - Westport

4.0 star property
8.2 out of 10, Very Good, (1008)
"Great stay"
The price is SAR 475
SAR 551 total
includes taxes & fees
28 Aug - 29 Aug
DoubleTree by Hilton St. Louis - Westport
Hilton St. Louis Frontenac
Lobby

Hilton St. Louis Frontenac

4.0 star property
8.8 out of 10, Excellent, (1007)
"On site restaurant, close a major highway, good quiet area, beds were cozy. "
The price is SAR 539
SAR 628 total
includes taxes & fees
7 Sep - 8 Sep
Hilton St. Louis Frontenac
DoubleTree by Hilton Hotel St. Louis - Chesterfield
Exterior

DoubleTree by Hilton Hotel St. Louis - Chesterfield

4.0 star property
8.6 out of 10, Excellent, (1001)
"Beautiful property, pleasant and responsive staff, delicious warm cookies! And convenient location near city hall and police department. "
The price is SAR 563
SAR 653 total
includes taxes & fees
29 Aug - 30 Aug
DoubleTree by Hilton Hotel St. Louis - Chesterfield
The Inn at Elijah McLeans
Balcony view

The Inn at Elijah McLeans

4.0 star property
9.0 out of 10, Wonderful, (124)
"Wasn’t terrible just smaller than expected and no breakfast offered. Wasn’t in the greatest area either seemingly. Will be staying at River sirens for similar price "
The price is SAR 491
SAR 559 total
includes taxes & fees
20 Aug - 21 Aug
The Inn at Elijah McLeans
Overlook Main St. in this 2 Bedroom Owners Suite!
Fridge, microwave, oven, stovetop

Overlook Main St. in this 2 Bedroom Owners Suite!

4.0 star property
9.4 out of 10, Exceptional, (32)
"Perfect place for a visit to St Charles! Hope to return and stay here again!"
Overlook Main St. in this 2 Bedroom Owners Suite!
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Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighboring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance

Top Defiance Hotel Reviews

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac

10/10 Excellent
"Great"
john 4-night trip
Posted 3 days ago
Hilton St. Louis Frontenac

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Defiance?
We can help you easily track down the perfect 4-star hotel for your vacation in Defiance. Use our filter tool to tailor your search by things like budget, conveniences and star rating and get access to awesome deals in a few clicks.

  • Search for the lowest price from SAR 475

What's the difference between 5-star and 4-star hotels in Defiance?
Offering an inviting guest experience and upscale décor, 4-star hotels are a fabulous option for your Defiance break. These kinds of accommodations generally feature loads of handy amenities that make it simple to kick back and relax — think large beds, bathrobes, gyms and restaurants. Or live the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. Concierge assistance, complimentary toiletries and fine dining are typically included at these deluxe retreats.
Does Defiance have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to search for your dream hotel in Defiance where everything is taken care of, from your accommodations to your meals, activities and entertainment. We can also help you find standard 4-star stays in and around this leading destination.