A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

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Our top choices for Defiance 4-star hotels

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,005 reviews)
"Great stay!"
United States
Matiah
The price is SAR 598
SAR 761 total
includes taxes & fees
19 Jul - 20 Jul
Ameristar Casino Resort and Spa

DoubleTree by Hilton St. Louis - Westport

DoubleTree by Hilton St. Louis - Westport
4.0 star property
Westport
8.0 out of 10, Very Good, (1,002 reviews)
"Very good hotel with excellent service."
United States
Yanetzy
The price is SAR 468
SAR 543 total
includes taxes & fees
28 Jun - 29 Jun
DoubleTree by Hilton St. Louis - Westport

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
Frontenac
8.8 out of 10, Excellent, (1,002 reviews)
"Always a nice time at the Frontenac!!!"
United States
Megan
The price is SAR 507
SAR 591 total
includes taxes & fees
5 Jul - 6 Jul
Hilton St. Louis Frontenac

DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
4.0 star property
Chesterfield
8.8 out of 10, Excellent, (1,001 reviews)
"The front desk staff were very friendly and accommodating!"
United States
Michelle
The price is SAR 539
SAR 625 total
includes taxes & fees
19 Jul - 20 Jul
DoubleTree by Hilton Hotel St. Louis - Chesterfield

The Inn at Elijah McLeans

The Inn at Elijah McLeans
4.0 star property
Washington
8.8 out of 10, Excellent, (150 reviews)
"Clean and right on the waterfront"
United States
Derek
The price is SAR 486
SAR 553 total
includes taxes & fees
28 Jun - 29 Jun
The Inn at Elijah McLeans

'the Ruebling House': Bright, Modern, & Renovated!

'the Ruebling House': Bright, Modern, & Renovated!
4.0 star property
Defiance
'the Ruebling House': Bright, Modern, & Renovated!

Landing Apartments - Eureka

Landing Apartments - Eureka
4.0 star property
Eureka
Landing Apartments - Eureka
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Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighboring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Top Defiance Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Defiance?
We can help you easily track down the perfect 4-star hotel for your vacation in Defiance. Use our filter tool to tailor your search by things like budget, conveniences and star rating and get access to awesome deals in a few clicks.

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What's the difference between 5-star and 4-star hotels in Defiance?
Offering an inviting guest experience and upscale décor, 4-star hotels are a fabulous option for your Defiance break. These kinds of accommodations generally feature loads of handy amenities that make it simple to kick back and relax — think large beds, bathrobes, gyms and restaurants. Or live the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. Concierge assistance, complimentary toiletries and fine dining are typically included at these deluxe retreats.
Does Defiance have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to search for your dream hotel in Defiance where everything is taken care of, from your accommodations to your meals, activities and entertainment. We can also help you find standard 4-star stays in and around this leading destination.