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Find hotels in Santa Ana, Panama City from SAR 155

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23 Jul - 24 Jul
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24 Jul - 25 Jul
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25 Jul - 27 Jul
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1 Aug - 3 Aug

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Discover 1,467 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Radisson Hotel Panama Canal
2 outdoor pools, pool umbrellas, sun loungers

Radisson Hotel Panama Canal

4.5 star property
8.4 out of 10, Very Good, (1001)
"very friendly staff"
The price is SAR 300
SAR 330 total
includes taxes & fees
22 Aug - 23 Aug
Radisson Hotel Panama Canal
Riande Aeropuerto Hotel & Casino
Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas

Riande Aeropuerto Hotel & Casino

4.0 star property
8.4 out of 10, Very Good, (1886)
"The rooms were clean, the breakfast was delicious and having a bar and restaurant on the premises was bonus!"
The price is SAR 439
SAR 483 total
includes taxes & fees
24 Jul - 25 Jul
Riande Aeropuerto Hotel & Casino
Crowne Plaza Panama Airport by IHG
Outdoor pool, pool umbrellas, sun loungers

Crowne Plaza Panama Airport by IHG

4.0 star property
8.4 out of 10, Very Good, (2163)
"Great hotel"
The price is SAR 450
SAR 495 total
includes taxes & fees
9 Aug - 10 Aug
Crowne Plaza Panama Airport by IHG
Casco View Apartments
Luxury Apartment | Balcony

Casco View Apartments

3.0 star property
9.2 out of 10, Wonderful, (41)
"I liked the buildings quietness and modern style."
Casco View Apartments
Room-sofa Bed Stay Rooftop Pool & Gym, A
Room, Multiple Bedrooms, Accessible, Smoking | Pool | Outdoor pool

Room-sofa Bed Stay Rooftop Pool & Gym, A

2.0 star property
The price is SAR 529
SAR 582 total
includes taxes & fees
31 Jul - 1 Aug
Room-sofa Bed Stay Rooftop Pool & Gym, A
ART CASCO The Hotel
Front of property

ART CASCO The Hotel

2.0 star property
7.0 out of 10, Good, (4)
"Excelente atención "
ART CASCO The Hotel
Hostal La Cigarra
Bar (on property)

Hostal La Cigarra

2.5 star property
7.4 out of 10, Good, (47)
"Great budget place to stay. Friendly, clean, good location. Would be happy to stay again in future."
Hostal La Cigarra
w Charming 1BR in Santa Ana s Best Area
Apartment | 1 bedroom, Internet

w Charming 1BR in Santa Ana s Best Area

2.0 star property
w Charming 1BR in Santa Ana s Best Area
Hotel República
Balcony

Hotel República

2.0 star property
6.6 out of 10, (171)
"The wifi is strong enough to use for work. "
Hotel República
La Manzana by Wynwood House
Apartment (20) | 1 bedroom, iron/ironing board, free WiFi, bed sheets

La Manzana by Wynwood House

3.5 star property
6.8 out of 10, (11)
"Great hotel. Very close to Casco viejo"
The price is SAR 182
SAR 276 total
includes taxes & fees
24 Jul - 25 Jul
La Manzana by Wynwood House
Casa Quijano 06 By Wynwood House
Apartment | Terrace/patio

Casa Quijano 06 By Wynwood House

4.0 star property
9.4 out of 10, Exceptional, (3)
"The apartment itself was very nice, very spacious, clean, newer furniture. Just know it’s on the third floor and there is no elevator. I didn’t see a sign on the building so it was a bit tricky to figure out which door to go to after being dropped off by the Uber. Email communication from property with building entry code and picture of the property was helpful. There are two balconies but all you really see is the apartment immediately in front of you, and so just know people can see you if you...
The price is SAR 243
SAR 391 total
includes taxes & fees
24 Jul - 25 Jul
Casa Quijano 06 By Wynwood House
Hotel Riazor
Single Room | 1 bedroom, free WiFi, bed sheets

Hotel Riazor

3.0 star property
3.8 out of 10, (10)
"Rough neighborhood "
Hotel Riazor
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Suite, 1 Bedroom, Non Smoking, Golf View (Terrace) | 1 bedroom, premium bedding, minibar, in-room safe

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (590)
"The staff was very friendly. "
The price is SAR 766
SAR 843 total
includes taxes & fees
1 Aug - 2 Aug
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Arcadia Condo Suites
50-inch LED TV with satellite channels

Arcadia Condo Suites

2.5 star property
9.4 out of 10, Exceptional, (39)
"The view, The location, the convenience. "
The price is SAR 371
SAR 582 total
includes taxes & fees
24 Jul - 25 Jul
Arcadia Condo Suites
The Westin Panama
Outdoor pool, pool umbrellas, sun loungers

The Westin Panama

4.0 star property
8.8 out of 10, Excellent, (287)
"Restaurant was under construction and food nearby was t the best but the hotel itself and staff were fantastic. "
The price is SAR 642
SAR 706 total
includes taxes & fees
2 Aug - 3 Aug
The Westin Panama
Panama House Bed & Breakfast
Terrace/patio

Panama House Bed & Breakfast

2.5 star property
9.0 out of 10, Wonderful, (164)
"The accommodations offered great value for the money. We appreciated the ability to bring our golden retriever, and have a parking spot in front. The owner and her staff were very friendly and helpful. The back area of the property, featuring green parrots and a blue macaw, added ambience and fun to the experience."
The price is SAR 155
SAR 170 total
includes taxes & fees
23 Aug - 24 Aug
Panama House Bed & Breakfast
Waymore Hotel Spa & Casino
Outdoor pool

Waymore Hotel Spa & Casino

4.0 star property
9.2 out of 10, Wonderful, (359)
"Great hotel for the price."
The price is SAR 287
SAR 398 total
includes taxes & fees
2 Aug - 3 Aug
Waymore Hotel Spa & Casino
Courtyard by Marriott Panama Metromall
Breakfast, lunch, dinner served; international cuisine

Courtyard by Marriott Panama Metromall

4.0 star property
8.8 out of 10, Excellent, (1005)
"I really enjoyed my stay there. "
The price is SAR 469
SAR 516 total
includes taxes & fees
30 Jul - 31 Jul
Courtyard by Marriott Panama Metromall
W Panama
2 restaurants, local cuisine

W Panama

5.0 star property
8.8 out of 10, Excellent, (1006)
"Beautiful hotel, highly recommend "
The price is SAR 644
SAR 709 total
includes taxes & fees
22 Aug - 23 Aug
W Panama
The Beach House
View from room

The Beach House

3.0 star property
8.4 out of 10, Very Good, (390)
"This was a great stay! We enjoyed the view from our balcony, I mean, on one side Panama City and on the other side Amador and the Pacific. We even enjoyed watching raccoons play on the surf. The breakfast was ok. But Nextdoor was the great Ranchito Restaurant which served like the best sangria ever. I had a seafood soup which was very tasty. So I am definitely going back on my next stay."
The price is SAR 292
SAR 321 total
includes taxes & fees
31 Jul - 1 Aug
The Beach House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.
Casco Viejo map

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Bella Vista map

Bella Vista

1 out of top 10 points of interest in this area

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo map

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Francisco map

San Francisco

1 out of top 10 points of interest in this area

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Punta Paitilla map

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Top Santa Ana Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Best breakfast I have ever had at a hotel. Hands down. So many options. The hotel is very lovely, spacious and comfortable. Only thing that bothered me is you could hear people walking or running above you at night. Hotel is very busy and guests are loud sometimes if you’re a light sleeper like me. Great WiFi, double sinks, great ac. I will definitely be back !"
Terri 2-night trip
Posted 18 hours ago
Hotel Riu Plaza Panama

Frequently asked questions

What's it like in Santa Ana?

Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Cinta Costera and Avenida Balboa while you're in the neighborhood.

Where is the best hotel for a stay in Santa Ana?

Based on Expedia customer reviews, Hotel República is the highest ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi. Another top choice in the area is Hostal La Cigarra.

How many hotels can I expect to find in Santa Ana?

Expedia has 101 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.

Where can I learn more about changing or cancelling my trip to Santa Ana?

To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.

What is there to do in this Panama City neighborhood?

If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighborhood. Albrook Shopping Mall, Amador Theater, and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.