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Discover 1,270 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama
Front of property
Hotel Riu Plaza Panama
5.0 star property
9.0 out of 10, Wonderful, (2507)
"It was very clean and staff was friendly "
The price is SAR 431
SAR 474 total
includes taxes & fees
16 Jum. II - 17 Jum. II
Hotel Riu Plaza Panama
JW Marriott Panama
Pool
JW Marriott Panama
5.0 star property
8.8 out of 10, Excellent, (1004)
"Excellent"
The price is SAR 867
SAR 939 total
includes taxes & fees
21 Jum. II - 22 Jum. II
JW Marriott Panama
W Panama
Exterior
W Panama
5.0 star property
8.8 out of 10, Excellent, (996)
"Highly recommend! Stay at the W was wonderful "
The price is SAR 762
SAR 825 total
includes taxes & fees
15 Jum. II - 16 Jum. II
W Panama
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Marriott Panama Hotel
Pool
Marriott Panama Hotel
4.0 star property
9.0 out of 10, Wonderful, (1004)
"We really liked the property, the staff was nice, they were kind, offered help literally on every task, took our luggage to the room, the breakfast was to die for, the rooftop bar with the pool, happy hour and the view was spectacular. "
The price is SAR 539
SAR 593 total
includes taxes & fees
14 Jum. II - 15 Jum. II
Marriott Panama Hotel
Sofitel Legend Casco Viejo, Panama City
Exterior detail
Sofitel Legend Casco Viejo, Panama City
5.0 star property
9.8 out of 10, Exceptional, (227)
"Excellent"
The price is SAR 1,097
SAR 1,207 total
includes taxes & fees
6 Jum. II - 7 Jum. II
Sofitel Legend Casco Viejo, Panama City
Las Americas Golden Tower Panama
Room
Las Americas Golden Tower Panama
4.0 star property
8.8 out of 10, Excellent, (882)
"It was a good stay!"
The price is SAR 472
SAR 520 total
includes taxes & fees
4 Jum. II - 5 Jum. II
Las Americas Golden Tower Panama
Hospedium Princess Hotel Panama
Pool
Hospedium Princess Hotel Panama
3.5 star property
7.6 out of 10, Good, (271)
"Close to the Airport...Easy check in process. Communication from booking to arrival Cancellation no charge policy within the stipulated time frame "
The price is SAR 229
SAR 252 total
includes taxes & fees
9 Jum. II - 10 Jum. II
Hospedium Princess Hotel Panama
Ramada Plaza By Wyndham Panama Punta Pacífica
Exterior
Ramada Plaza By Wyndham Panama Punta Pacífica
4.0 star property
9.4 out of 10, Exceptional, (1006)
"Good friendly and kind Good restaurant "
The price is SAR 439
SAR 483 total
includes taxes & fees
16 Jum. II - 17 Jum. II
Ramada Plaza By Wyndham Panama Punta Pacífica
Euro Hotel
Outdoor pool
Euro Hotel
3.0 star property
7.6 out of 10, Good, (523)
"The hotel was well worth the money I paid. Restaurant was nice for breakfast. The hotel was clean and staff was friendly. "
The price is SAR 124
SAR 136 total
includes taxes & fees
17 Jum. II - 18 Jum. II
Euro Hotel
AC Hotel by Marriott Panama City
Pool
AC Hotel by Marriott Panama City
3.5 star property
9.0 out of 10, Wonderful, (423)
"Javier and the staff are great"
The price is SAR 357
SAR 387 total
includes taxes & fees
29 Jum. II - 30 Jum. II
AC Hotel by Marriott Panama City
Central Hotel Panama Casco Viejo
Rooftop pool
Central Hotel Panama Casco Viejo
4.0 star property
9.0 out of 10, Wonderful, (687)
"Although the staff at reception was a little not accommodating based on the amenities I had to get from my membership this was resolved. Overall very comfortable stay and will stay again. The taxi guys at the entrance were a bit to over bearing though. "
The price is SAR 835
SAR 919 total
includes taxes & fees
4 Jum. II - 5 Jum. II
Central Hotel Panama Casco Viejo
Summit Rainforest & Golf Resort
Outdoor pool
Summit Rainforest & Golf Resort
4.0 star property
8.4 out of 10, Very Good, (1002)
"The hotel is clean , food isn’t good,"
The price is SAR 254
SAR 280 total
includes taxes & fees
5 Jum. II - 6 Jum. II
Summit Rainforest & Golf Resort
Holiday Inn Panama Distrito Financiero, an IHG Hotel
Exterior
Holiday Inn Panama Distrito Financiero, an IHG Hotel
4.0 star property
8.8 out of 10, Excellent, (1001)
"All "
The price is SAR 304
SAR 375 total
includes taxes & fees
7 Jum. II - 8 Jum. II
Holiday Inn Panama Distrito Financiero, an IHG Hotel
Hotel Coral Suites
Sundeck
Hotel Coral Suites
3.5 star property
8.8 out of 10, Excellent, (963)
"staff was great"
The price is SAR 285
SAR 314 total
includes taxes & fees
4 Jum. II - 5 Jum. II
Hotel Coral Suites
Bristol Panama, a Registry Collection Hotel
Room
Bristol Panama, a Registry Collection Hotel
5.0 star property
9.2 out of 10, Wonderful, (1001)
"The best parts were cleanliness, and one of the best restaurants he 5th floor. The food was outstanding. "
The price is SAR 677
SAR 744 total
includes taxes & fees
6 Jum. II - 7 Jum. II
Bristol Panama, a Registry Collection Hotel
Residence Inn by Marriott Panama City
Exterior
Residence Inn by Marriott Panama City
4.0 star property
9.0 out of 10, Wonderful, (328)
"Excellent stay. Super clean. Quiet. The only subpar encounters were in the bar, where although the service was friendly it was VERY slow even when no other patrons were there."
The price is SAR 540
SAR 588 total
includes taxes & fees
21 Jum. II - 22 Jum. II
Residence Inn by Marriott Panama City
Torres de Alba Hotel & Suites
Exterior
Torres de Alba Hotel & Suites
3.5 star property
8.8 out of 10, Excellent, (366)
"The property manager, Carlos speaks English very well. He's very friendly and really wants the customers who stay there to enjoy their time there. All of the staff is very friendly and helpful. The hotel is very clean and the bed is very comfortable. We have stayed there several times before and will be staying there again when we return to Panamá. "
The price is SAR 353
SAR 388 total
includes taxes & fees
4 Jum. II - 5 Jum. II
Torres de Alba Hotel & Suites
Marriott Executive Apartments Panama City, Finisterre
Pool
Marriott Executive Apartments Panama City, Finisterre
4.0 star property
8.8 out of 10, Excellent, (512)
"To me the area seems safe and accessible considering being a wheelchair user and that the hotel and property is wheelchair accessible but a lift system should be added to the pool. The staff was nice. Don’t like that the Gym is a bit small not a good enough options to choose from with workouts also the breakfast buffet can have a few more options added. bathroom is a bit small for people in wheelchairs but the rooms are very spacious and was clean overall my stay was spent without any major...
The price is SAR 357
SAR 387 total
includes taxes & fees
22 Jum. II - 23 Jum. II
Marriott Executive Apartments Panama City, Finisterre
Hotel Ojos del Rio
Terrace/patio
Hotel Ojos del Rio
3.5 star property
8.2 out of 10, Very Good, (583)
"Verynice place "
The price is SAR 166
SAR 184 total
includes taxes & fees
14 Jum. II - 15 Jum. II
Hotel Ojos del Rio
Gamboa Rainforest Reserve
Aerial view
Gamboa Rainforest Reserve
3.5 star property
7.6 out of 10, Good, (543)
"Beautiful setting, amazing view!"
The price is SAR 357
SAR 401 total
includes taxes & fees
24 Jum. II - 25 Jum. II
Gamboa Rainforest Reserve
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Frequently asked questions

What's it like in Santa Ana?

Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Avenida Central and Cinta Costera while you're in the neighborhood.

How many hotels can I expect to find in Santa Ana?

Expedia has 88 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.

Where can I learn more about changing or cancelling my trip to Santa Ana?

To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.

What is there to do in this Panama City neighborhood?

If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighborhood. Albrook Shopping Mall, Amador Theater, and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.

Recent reviews of Santa Ana hotels

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5/5 Excellent
"It was very clean and staff was friendly "
A verified traveler stayed at Hotel Riu Plaza Panama
Posted 7 hours ago
Hotel Riu Plaza Panama