The Best Hotels Closest to Duke Regional Hospital in Raleigh for 2026

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Our top choices for Duke Regional Hospital hotels

A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.

A Hampton Inn hotel with a modern facade, multiple floors, and a parking lot.

A hotel room with a bed, a desk with a chair, a flat-screen TV, a microwave, and a mirror.

A large indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls, with large windows allowing natural light.

1. Hampton Inn & Suites Durham/North I-85

2.2 km from Duke Regional Hospital

Mohammed

SAR 459

SAR 521 total

includes taxes & fees

1 Nov - 2 Nov

A buffet setup with various food items in metal containers, a patterned wall, and a counter with utensils.

A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.

A hotel lobby with a sofa, chairs, a coffee table, a TV, and a patterned carpet.

2. Holiday Inn Express Durham by IHG

2.4 km from Duke Regional Hospital

Kimberly R

SAR 413

SAR 469 total

includes taxes & fees

8 Nov - 9 Nov

A Red Roof Inn lobby with a stone wall, wooden flooring, and a seating area with chairs and a small table.

A reception desk with a 'Free Wi-Fi All Rooms' sign, a cash register, and a credit card reader.

A motel with a red and white sign, multiple balconies, and a parking lot.

A hotel bathroom with a beige armchair, a towel rack, a mirror, and a sink.

3. Red Roof Inn Durham - Duke Univ Medical Center

2.3 km from Duke Regional Hospital

Richard

SAR 235

SAR 273 total

includes taxes & fees

1 Nov - 2 Nov

4. Super 8 by Wyndham Durham/University Area NC

2.4 km from Duke Regional Hospital

Jacqueline

SAR 246

SAR 278 total

includes taxes & fees

8 Nov - 9 Nov

A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.

A Hampton Inn & Suites hotel with a modern facade, multiple windows, and a parking lot.

A modern dining area with a long table, multiple chairs, and a sofa with red ottomans.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

5. Hampton Inn & Suites Durham University Medical Center

5 km from Duke Regional Hospital

LaGrant

SAR 510

SAR 579 total

includes taxes & fees

23 Nov - 24 Nov

A modern lobby with a central seating area, a TV screen, and a patterned wall.

A modern hotel room with a bed, bedside table, TV, and a small desk area.

A modern kitchen with a built-in refrigerator, a gray sofa, and a gray armchair.

An indoor swimming pool with clear water, surrounded by lounge chairs and potted plants.

6. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

18.2 km from Duke Regional Hospital

Maurice

SAR 443

SAR 502 total

includes taxes & fees

1 Nov - 2 Nov

A modern living room with a fireplace, comfortable seating, and a large window with curtains.

A courtyard with a pathway leading to a building with large windows and a yellow facade.

A swimming pool with lounge chairs and a view of a building with large windows.

A hotel reception area with a counter, coffee station, and a large window with curtains.

7. La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

North Garrett Road, 10.4 km from Duke Regional Hospital

Barbara

SAR 308

SAR 350 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with clear water, a no diving sign, and a seating area with chairs and tables.

A modern kitchen with built-in shelves, a glass backsplash, and a variety of kitchenware.

A modern hotel lobby with a sectional sofa, armchairs, and a coffee table.

A modern hotel lobby with a long dining table, multiple chairs, a sofa, and a bar area.

8. Hyatt House Raleigh / RDU / Brier Creek

17.8 km from Duke Regional Hospital

Shelby

SAR 413

SAR 468 total

includes taxes & fees

1 Nov - 2 Nov

A reception area with two wooden reception desks, a potted plant, and a computer on the wall.

A hotel room with a sofa, a small table, a desk, a chair, a TV, and a window with curtains.

A hotel room with two beds, a desk, a chair, a TV, and a bathroom.

9. Courtyard Raleigh-Durham Airport/Brier Creek

16.6 km from Duke Regional Hospital

Cristian

SAR 497

SAR 563 total

includes taxes & fees

31 Oct - 1 Nov

An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.

A modern living room with a fireplace, two sofas, a coffee table, and a TV mounted on the wall.

A multi-story hotel with a brick facade, large windows, and a well-lit entrance.

A modern restaurant with round tables and yellow chairs, a bar area, and a 'Hello Fall' sign.

10. Fairfield by Marriott Inn & Suites Durham

18.2 km from Duke Regional Hospital

Chip

SAR 445

SAR 506 total

includes taxes & fees

8 Nov - 9 Nov

A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.

A Hilton Garden Inn hotel with a modern design, featuring a large entrance and a parking area with a delivery van.

A business center with wooden paneling, multiple workstations, and framed artwork on the walls.

An indoor swimming pool with clear glass walls, a tiled floor, and a seating area with chairs and a table.

11. Hilton Garden Inn Durham/University Medical Center

9th Street District, 4 km from Duke Regional Hospital

Anne

SAR 469

SAR 532 total

includes taxes & fees

22 Nov - 23 Nov

A spacious lobby with high ceilings, a central fountain, and seating areas.

An outdoor patio area with wicker furniture, stone pillars, and string lights.

A spacious lobby with a curved seating area, large windows, and a modern chandelier.

A bar area with multiple liquor cabinets and hanging pendant lights.

12. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

18.2 km from Duke Regional Hospital

Darren C.

SAR 597

SAR 676 total

includes taxes & fees

8 Nov - 9 Nov

A modern hotel with a prominent entrance, multiple floors, and a balcony on the second floor.

An outdoor patio with a fire feature, seating, and a building with large windows.

A modern hotel room with a bed, a desk, a chair, a small seating area, and a kitchenette.

A modern hotel lobby with a reception desk, a beverage refrigerator, and a well-stocked snack bar.

13. SpringHill Suites by Marriott Durham City View

5.4 km from Duke Regional Hospital

Jeff

SAR 482

SAR 547 total

includes taxes & fees

1 Nov - 2 Nov

A hotel entrance with a stone facade, large wooden doors, and a view into the interior.

A dining area with a chandelier, tables, chairs, and a Christmas tree.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and potted plants.

A hotel with a stone lion statue, a covered entrance, and a landscaped garden.

14. Washington Duke Inn & Golf Club

6.6 km from Duke Regional Hospital

Lowell

SAR 901

SAR 1,022 total

includes taxes & fees

27 Oct - 28 Oct

A hotel room with a bed, a desk, a chair, a small table, a coffee machine, and a trash bin.

A swimming pool with lounge chairs and umbrellas, surrounded by a building with a clear sky.

A reception area with a wooden reception desk, blue seating, a flat-screen TV, and a stone accent wall.

A restaurant with a large ice dispenser, wooden paneling, and red cushioned booths.

15. Comfort Inn & Suites Durham near Duke University

Croasdaile Farm Master, 3.3 km from Duke Regional Hospital

Robert

SAR 340

SAR 386 total

includes taxes & fees

1 Nov - 2 Nov

A spacious indoor dining area with high ceilings, large windows, and modern furniture.

A hotel hallway with a bench, a reception desk, and a plant.

A hotel lobby with a reception desk, potted plants, a herringbone floor pattern, and a view of the dining area.

A spacious indoor area with wooden flooring, multiple seating arrangements, and large windows offering a view of the outdoors.

16. DoubleTree Suites by Hilton Raleigh - Durham

14.2 km from Duke Regional Hospital

Sierra

SAR 367

SAR 416 total

includes taxes & fees

22 Nov - 23 Nov

An outdoor seating area with sofas, chairs, and a fire pit, adjacent to a modern building with large windows.

A modern kitchen with a central island, bar stools, wooden cabinets, and pendant lighting.

A modern reception area with a marble counter, a wooden bench, and a unique chandelier.

A modern living room with a fireplace, seating area, and a pool table.

17. JB Duke Hotel

6.2 km from Duke Regional Hospital

samantha

SAR 732

SAR 831 total

includes taxes & fees

25 Nov - 26 Nov

An outdoor seating area with wicker furniture and a stone fire pit.

An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.

A modern hotel lobby with seating areas, large windows, and a dining section.

A conference room with a long table, chairs, and a modern chandelier.

18. Residence Inn Raleigh-Durham Airport/Brier Creek

16.6 km from Duke Regional Hospital

Janet

SAR 523

SAR 593 total

includes taxes & fees

31 Oct - 1 Nov

A bar area with wooden bar stools, pendant lighting, and a counter with a glass display. There are tables and chairs in the background, and the room has a wooden floor.

A covered porch with steps leading to a door, a brick wall, and a street lamp.

A bar area with wooden shelves, a chalkboard menu, and various bottles.

A hotel room with two beds, a sofa, a TV, and a bathroom visible through a door.

19. The Colonial Inn, an Ascend Collection Hotel

18.6 km from Duke Regional Hospital

Matt W

SAR 423

SAR 480 total

includes taxes & fees

1 Nov - 2 Nov

A modern hotel reception area with two wooden reception desks, a large digital display wall, and a seating area with chairs.

A hotel room with two beds, a desk, and a chair.

A modern restaurant with bar seating, a Starbucks sign, and a bar area with a counter and shelves.

20. Hilton Durham near Duke University

5.4 km from Duke Regional Hospital

Isaac

SAR 397

SAR 451 total

includes taxes & fees

23 Nov - 24 Nov

View all properties

Compare popular hotels close to Duke Regional Hospital

Property	Property class	Guest rating
Hampton Inn & Suites Durham/North I-85	9.0 Wonderful 1,002 reviews	View
Holiday Inn Express Durham by IHG	8.8 Excellent 1,000 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	6.8 1,003 reviews	View
Super 8 by Wyndham Durham/University Area NC	5.0 344 reviews	View
Hampton Inn & Suites Durham University Medical Center	9.6 Exceptional 589 reviews	View

Top Duke Regional Hospital Hotel Reviews

Red Roof Inn Durham - Duke Univ Medical Center

8/10 Good

"Convenient location for me,priced was cheap,i got a standard room,no fridge,or microwave, that's on me,should have read room description better,overall fair rating,not luxurious at all,neighborhood was iffy,just be alert of your surroundings,"

The Lodge at Duke Medical Center

8/10 Good

"Can’t beat the parking and convenience to Duke University Hospital. I stay often and will continue to do so. Unfortunately there is almost no sound proofing between the rooms. Expect to enjoy your neighbor’s conversation and TV. For this price range it is below par. Even the breakfast has good options and fair prices."

Courtyard Durham Near Duke University/Downtown

8/10 Good

"The staff was great. The young lady at the front desk was very nice. The carpet in the hallway looks old and stained. The shower on first glance looked clean but once inside you can see black mold around the fixtures and edge of tub. Sheets felt odd like they were pilled. All in all an okay stay. Very near to the interstate and within walking distance of two nice restaurants."

Cottage with Yard, Mins to Duke

10/10 Excellent

"This is such a sweet cottage, so many details and there are instructions for EVERYTHING! NO guessing how to operate anything, they thought of it all,highly recommend to anyone! You can tell how much they care about every detail. I have stayed in many rentals and I can tell you this is a great deal for what you pay...very comfy beds, great linnens and the outdoor deck and front porch are a great bonus,plus there is a fireplace, but bring some starter kindling.Location is close to everything. Again, great value,it is really a little happy place,filled with little treasures!"

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

10/10 Excellent

"Super cute and clean!"

Everything within 1 mile

10/10 Excellent

"This home is thoughtfully laid out and much more spacious than it looks in photos. Our kids enjoyed the snacks each night, and their grandma loved that the home is all one level with smooth floors and bright lighting. Location was perfect for attending events in Durham, Wake Forest and Raleigh. There's also a running path across the street."

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

10/10 Excellent

"!"

Not Your Average Stay” +Glow Room by 9th St, Duke, Alexa,Games & WiFi + NEW! 2bd

10/10 Excellent

"We loved it! Rooms were large and well decorated, everything was so cute! We played football in the yard and lots of other games. The neighborhood is really nice and safe too. Lots of kids and families. I would definitely stay again!"

Tiny Home a fantastic Location close to 9th Street!

10/10 Excellent

"Loved the space it was very cozy and cute"

Frequently asked questions

What's the area like around Duke Regional Hospital?

Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Duke Regional Hospital?

Courtyard Durham Near Duke University/Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 2.2 mi (3.5 km) from Duke Regional Hospital. Other good choices within a few miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.

How many hotels can I expect to find near Duke Regional Hospital?

Expedia has 10 hotels and other accommodations within a mile from Duke Regional Hospital.

If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?

Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.

Where can I learn more about changing or cancelling my trip in the area near Duke Regional Hospital?

To find more details about changing or cancelling your stay near Duke Regional Hospital, click here.

What can I see and do near Duke Regional Hospital?

You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Find hotels near Duke Regional Hospital, Raleigh from SAR 273

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Treat yourself

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Our top choices for Duke Regional Hospital hotels

1. Hampton Inn & Suites Durham/North I-85

2. Holiday Inn Express Durham by IHG

3. Red Roof Inn Durham - Duke Univ Medical Center

4. Super 8 by Wyndham Durham/University Area NC

5. Hampton Inn & Suites Durham University Medical Center

6. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

7. La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

8. Hyatt House Raleigh / RDU / Brier Creek

9. Courtyard Raleigh-Durham Airport/Brier Creek

10. Fairfield by Marriott Inn & Suites Durham

11. Hilton Garden Inn Durham/University Medical Center

12. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

13. SpringHill Suites by Marriott Durham City View

14. Washington Duke Inn & Golf Club

15. Comfort Inn & Suites Durham near Duke University

16. DoubleTree Suites by Hilton Raleigh - Durham

17. JB Duke Hotel

18. Residence Inn Raleigh-Durham Airport/Brier Creek

19. The Colonial Inn, an Ascend Collection Hotel

20. Hilton Durham near Duke University

Compare popular hotels close to Duke Regional Hospital

Top Duke Regional Hospital Hotel Reviews

Red Roof Inn Durham - Duke Univ Medical Center

The Lodge at Duke Medical Center

Courtyard Durham Near Duke University/Downtown

Cottage with Yard, Mins to Duke

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

Everything within 1 mile

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

Not Your Average Stay” +Glow Room by 9th St, Duke, Alexa,Games & WiFi + NEW! 2bd

Tiny Home a fantastic Location close to 9th Street!

Frequently asked questions