The Best Hotels Closest to Duke Regional Hospital in Raleigh for 2026

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Our top choices for Duke Regional Hospital hotels

A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.

A large indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls, with large windows allowing natural light.

A Hampton Inn hotel with a modern facade, multiple floors, and a parking lot.

A narrow hallway with shelves stocked with snacks and beverages, leading to a room with a desk and chair.

1. Hampton Inn & Suites Durham/North I-85

2.2 km from Duke Regional Hospital

Shwetha

SAR 459

SAR 521 total

includes taxes & fees

8 Nov - 9 Nov

A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.

A Holiday Inn Express hotel with a modern design, featuring a prominent sign, multiple windows, and a well-lit entrance.

A swimming pool with a metal railing, surrounded by a building with multiple windows and a sign indicating no lifeguard on duty.

A hotel lobby with a seating area, a reception desk, and artwork on the walls.

2. Holiday Inn Express Durham by IHG

2.4 km from Duke Regional Hospital

Kimberly R

SAR 387

SAR 439 total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with a television on a wooden cabinet, a desk with a chair, and a lamp.

A Red Roof Cafe with a stone wall, a coffee machine, and two white chairs.

A spacious hallway with wooden flooring, white walls, and multiple windows with blinds. There are two white chairs and a small table with a basket.

A hotel room with a bed, bedside tables, a nightstand, a mirror, and a bathroom with a sink and mirror.

3. Red Roof Inn Durham - Duke Univ Medical Center

2.3 km from Duke Regional Hospital

Luis

SAR 235

SAR 273 total

includes taxes & fees

15 Nov - 16 Nov

An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.

A modern restaurant with round tables and yellow chairs, a bar area, and a 'Hello Fall' sign.

A modern living room with a fireplace, two sofas, a coffee table, and a TV mounted on the wall.

A hotel room with two beds, a desk, a chair, a sofa, and a TV.

4. Fairfield by Marriott Inn & Suites Durham

18.2 km from Duke Regional Hospital

Chip

SAR 445

SAR 506 total

includes taxes & fees

25 Oct - 26 Oct

A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.

A modern hotel lobby with a reception desk, seating area, and a cityscape mural on the wall.

A Hampton Inn & Suites hotel with a modern facade, multiple windows, and a parking lot.

A modern dining area with a long table, multiple chairs, and a sofa with red ottomans.

5. Hampton Inn & Suites Durham University Medical Center

5 km from Duke Regional Hospital

Nicole

SAR 475

SAR 540 total

includes taxes & fees

25 Oct - 26 Oct

A modern lobby with a central seating area, a TV screen, and a patterned wall.

A reception area with a counter, a welcome sign, a digital screen, and a hallway leading to a dining area.

A modern hotel room with a bed, bedside table, TV, and a small desk area.

A modern kitchen with a built-in refrigerator, a gray sofa, and a gray armchair.

6. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

18.2 km from Duke Regional Hospital

Maurice

SAR 443

SAR 502 total

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with clear water, a no diving sign, and a seating area with chairs and tables.

A modern hotel lobby with a long dining table, multiple chairs, a sofa, and a bar area.

A modern hotel lobby with a sectional sofa, armchairs, and a coffee table.

A modern kitchen with built-in shelves, a glass backsplash, and a variety of kitchenware.

7. Hyatt House Raleigh / RDU / Brier Creek

17.8 km from Duke Regional Hospital

Shelby

SAR 413

SAR 468 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a sofa, a small table, a desk, a chair, a TV, and a window with curtains.

A hotel room with two beds, a desk, a chair, a TV, and a bathroom.

An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.

8. Courtyard Raleigh-Durham Airport/Brier Creek

16.6 km from Duke Regional Hospital

Sharon

SAR 501

SAR 568 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with high ceilings, a central fountain, and seating areas.

A spacious lobby with a curved seating area, large windows, and a modern chandelier.

An outdoor patio area with wicker furniture, stone pillars, and string lights.

A modern bedroom with a large bed, a fireplace, a walk-in closet, and a bathroom with a round mirror and vanity.

9. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

18.2 km from Duke Regional Hospital

Darren C.

SAR 597

SAR 676 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with wicker furniture and a stone fire pit.

A conference room with a long table, chairs, and a modern chandelier.

A hotel lobby with a sofa, chairs, a table, and a large window offering a view of the building.

A modern hotel lobby with seating areas, large windows, and a dining section.

10. Residence Inn Raleigh-Durham Airport/Brier Creek

16.6 km from Duke Regional Hospital

Janet

SAR 523

SAR 593 total

includes taxes & fees

1 Nov - 2 Nov

11. Home2 Suites by Hilton Durham University Medical Center

5 km from Duke Regional Hospital

katey

SAR 539

SAR 612 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with sofas, chairs, and a fire pit, adjacent to a modern building with large windows.

A modern reception area with a marble counter, a wooden bench, and a unique chandelier.

A modern living room with a fireplace, seating area, and a pool table.

A modern bar area with a long counter, multiple bar stools, and a large screen displaying a sports event.

12. JB Duke Hotel

6.2 km from Duke Regional Hospital

samantha

SAR 747

SAR 848 total

includes taxes & fees

11 Nov - 12 Nov

An outdoor seating area with tables and chairs, umbrellas, and potted plants.

A hotel room with a large bed, two bedside tables, and two wall-mounted lamps.

A tented outdoor dining area with round tables set for a meal, each with white chairs and yellow tablecloths.

An outdoor patio with a table set for a meal, surrounded by chairs and a red umbrella.

13. DoubleTree Suites by Hilton Raleigh - Durham

14.2 km from Duke Regional Hospital

Sierra

SAR 386

SAR 438 total

includes taxes & fees

5 Nov - 6 Nov

A modern living room with a pool table, a sofa, and a dining area.

A bar area with multiple shelves of bottles, glasses, and a bar counter.

A modern restaurant with long communal tables, hanging pendant lights, and geometric patterned walls.

14. The Westin Raleigh-Durham Airport

18.2 km from Duke Regional Hospital

Dina

SAR 807

SAR 914 total

includes taxes & fees

15 Nov - 16 Nov

A long, narrow hallway with dark walls and wooden flooring.

A modern reception area with a reception desk, a seating area with chairs and a table, and a bookshelf with books.

A compact kitchenette with a refrigerator, microwave, and a flat-screen TV on a dark cabinet.

15. University Inn Durham next to Duke University Medical Center

4.5 km from Duke Regional Hospital

Nicole

SAR 403

SAR 457 total

includes taxes & fees

30 Oct - 31 Oct

A hotel entrance with a stone facade, large wooden doors, and a view into the interior.

A hotel with a stone lion statue, a covered entrance, and a landscaped garden.

A dining area with a chandelier, tables, chairs, and a Christmas tree.

A person performing a yoga pose outdoors with trees and a golf course in the background.

16. Washington Duke Inn & Golf Club

6.6 km from Duke Regional Hospital

Lowell

SAR 901

SAR 1,022 total

includes taxes & fees

8 Nov - 9 Nov

A swimming pool with lounge chairs and a wooden fence.

A hotel room with a bed, a sofa, a desk with a chair, a television, and a painting on the wall.

A spacious lobby with a reception desk, seating area, and artwork on the walls.

A multi-story hotel with a modern design, featuring a prominent entrance with a glass canopy and an American flag.

17. Hyatt Place Durham Southpoint

16.1 km from Duke Regional Hospital

Jessica

SAR 507

SAR 575 total

includes taxes & fees

22 Oct - 23 Oct

A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.

A bar area with a granite countertop, wooden chairs, and a large television screen.

A business center with wooden paneling, multiple workstations, and framed artwork on the walls.

A Hilton Garden Inn hotel with a modern design, featuring a large entrance and a parking area with a delivery van.

18. Hilton Garden Inn Durham/University Medical Center

9th Street District, 4 km from Duke Regional Hospital

Michael

SAR 491

SAR 558 total

includes taxes & fees

9 Nov - 10 Nov

A brick pathway flanked by neatly trimmed hedges leading to a building with a red facade and a grey roof.

A spacious lobby with a long corridor, comfortable seating areas, and large windows providing natural light.

A modern living room with two sofas facing a glass coffee table, a large window with curtains, and a brick wall.

A restaurant with brick walls, wooden tables, and blue chairs.

19. Rizzo Center, a Destination by Hyatt Hotel

17 km from Duke Regional Hospital

Dale

SAR 672

SAR 763 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a nightstand with a lamp, and a window with a view of trees.

An outdoor seating area with tables and chairs, a paved walkway, and a fence.

A shelf stocked with various snack items, including boxed cereals and candy.

A coffee station with two coffee machines and a variety of coffee pods and cups.

20. Holiday Inn Express & Suites Raleigh Airport - Brier Creek by IHG

16.9 km from Duke Regional Hospital

Nathaniel

SAR 360

SAR 426 total

includes taxes & fees

16 Nov - 17 Nov

View all properties

Compare popular hotels close to Duke Regional Hospital

Property	Property class	Guest rating
Hampton Inn & Suites Durham/North I-85	9.0 Wonderful 1,000 reviews	View
Holiday Inn Express Durham by IHG	8.8 Excellent 1,000 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	6.8 1,000 reviews	View
Fairfield by Marriott Inn & Suites Durham	9.6 Exceptional 60 reviews	View
Hampton Inn & Suites Durham University Medical Center	9.6 Exceptional 575 reviews	View

Top Duke Regional Hospital Hotel Reviews

Comfort Inn & Suites Durham near Duke University

10/10 Excellent

"Breakfast was great!!!"

Hilton Durham near Duke University

10/10 Excellent

"Good location and has all ameneties for a comfortable stay"

Hampton Inn & Suites Durham/North I-85

10/10 Excellent

"Very clean room, and friendly staff"

Everything within 1 mile

10/10 Excellent

"This home is thoughtfully laid out and much more spacious than it looks in photos. Our kids enjoyed the snacks each night, and their grandma loved that the home is all one level with smooth floors and bright lighting. Location was perfect for attending events in Durham, Wake Forest and Raleigh. There's also a running path across the street."

The Lodge at Duke Medical Center

8/10 Good

"Very convenient to the medical center and university. The staff was very helpful. Good value. Very safe."

Unscripted Durham, Part of JDV by Hyatt

8/10 Good

"The place was awesome! I'm not going into details....I came home with some bed bug bites......🤔"

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

10/10 Excellent

"The house was absolutely immaculate and Kristin could not have nicer or more helpful. The location was just 25 minutes from RDU, 12 minutes from downtown Durham and about a half an hour from Chapel Hill. Comfortable living room for my small group, large screen TV with all the streaming channels and a very cool coffee grinder/maker for regular or espresso coffee. Highly recommend. John L"

Cottage with Yard, Mins to Duke

10/10 Excellent

"This was a cheerful home with comfortable beds and many thoughtful extras. We enjoyed our time here."

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

10/10 Excellent

"!"

Frequently asked questions

What's the area like around Duke Regional Hospital?

Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Duke Regional Hospital?

Courtyard Durham Near Duke University/Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 2.2 mi (3.5 km) from Duke Regional Hospital. Other good choices within a few miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.

How many hotels can I expect to find near Duke Regional Hospital?

Expedia has 10 hotels and other accommodations within a mile from Duke Regional Hospital.

If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?

Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.

Where can I learn more about changing or cancelling my trip in the area near Duke Regional Hospital?

To find more details about changing or cancelling your stay near Duke Regional Hospital, click here.

What can I see and do near Duke Regional Hospital?

You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Find hotels near Duke Regional Hospital, Raleigh from SAR 273

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Our top choices for Duke Regional Hospital hotels

1. Hampton Inn & Suites Durham/North I-85

2. Holiday Inn Express Durham by IHG

3. Red Roof Inn Durham - Duke Univ Medical Center

4. Fairfield by Marriott Inn & Suites Durham

5. Hampton Inn & Suites Durham University Medical Center

6. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

7. Hyatt House Raleigh / RDU / Brier Creek

8. Courtyard Raleigh-Durham Airport/Brier Creek

9. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

10. Residence Inn Raleigh-Durham Airport/Brier Creek

11. Home2 Suites by Hilton Durham University Medical Center

12. JB Duke Hotel

13. DoubleTree Suites by Hilton Raleigh - Durham

14. The Westin Raleigh-Durham Airport

15. University Inn Durham next to Duke University Medical Center

16. Washington Duke Inn & Golf Club

17. Hyatt Place Durham Southpoint

18. Hilton Garden Inn Durham/University Medical Center

19. Rizzo Center, a Destination by Hyatt Hotel

20. Holiday Inn Express & Suites Raleigh Airport - Brier Creek by IHG

Compare popular hotels close to Duke Regional Hospital

Top Duke Regional Hospital Hotel Reviews

Comfort Inn & Suites Durham near Duke University

Hilton Durham near Duke University

Hampton Inn & Suites Durham/North I-85

Everything within 1 mile

The Lodge at Duke Medical Center

Unscripted Durham, Part of JDV by Hyatt

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

Cottage with Yard, Mins to Duke

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

Frequently asked questions