The Best Hotels Closest to Duke Regional Hospital in Raleigh for 2026

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Our top choices for Duke Regional Hospital hotels

A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.

A narrow hallway with shelves stocked with snacks and beverages, leading to a room with a desk and chair.

A Hampton Inn hotel with a modern facade, multiple floors, and a parking lot.

A hotel room with a bed, a desk with a chair, a flat-screen TV, a microwave, and a mirror.

1. Hampton Inn & Suites Durham/North I-85

2.2 km from Duke Regional Hospital

Darrel

SAR 460

SAR 522 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.

A Holiday Inn Express hotel with a modern design, featuring a prominent sign, multiple windows, and a well-lit entrance.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.

A gym with various exercise machines, a large mirror, and a television on the wall.

2. Holiday Inn Express Durham by IHG

2.4 km from Duke Regional Hospital

Kimberly R

SAR 387

SAR 439 total

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a television on a wooden cabinet, a desk with a chair, and a lamp.

A Red Roof Cafe with a stone wall, a coffee machine, and two white chairs.

A hotel room with a bed, bedside tables, a nightstand, a mirror, and a bathroom with a sink and mirror.

A spacious hallway with wooden flooring, white walls, and multiple windows with blinds. There are two white chairs and a small table with a basket.

3. Red Roof Inn Durham - Duke Univ Medical Center

2.3 km from Duke Regional Hospital

Luis

SAR 235

SAR 274 total

includes taxes & fees

12 Oct - 13 Oct

A modern living room with a fireplace, comfortable seating, and a large window with curtains.

A swimming pool with lounge chairs and a view of a building with large windows.

A courtyard with a pathway leading to a building with large windows and a yellow facade.

A hotel reception area with a counter, coffee station, and a large window with curtains.

4. La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

North Garrett Road, 10.4 km from Duke Regional Hospital

Yolanda

SAR 315

SAR 357 total

includes taxes & fees

11 Oct - 12 Oct

A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.

A Hampton Inn & Suites hotel with a modern facade, multiple windows, and a parking lot.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

A modern hotel lobby with a reception desk, seating area, and a cityscape mural on the wall.

5. Hampton Inn & Suites Durham University Medical Center

5 km from Duke Regional Hospital

Nicole

SAR 511

SAR 580 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor seating area with wicker chairs and a large umbrella, a fire feature, and a view of the interior through glass walls.

A hotel room with a large bed, a bedside table with a lamp, a TV mounted on the wall, and a window with curtains.

A large indoor swimming pool with a skylight ceiling, clear glass walls, and a tiled floor.

A kitchen with a microwave, coffee maker, and a dishwasher.

6. DoubleTree Suites by Hilton Raleigh - Durham

14.2 km from Duke Regional Hospital

Stephen

SAR 387

SAR 439 total

includes taxes & fees

5 Nov - 6 Nov

A hotel room with a bed, a desk, a chair, a small table, a coffee machine, and a trash bin.

A Comfort Inn & Suites hotel with a modern design, featuring a prominent entrance and a landscaped front yard.

A restaurant with a large ice dispenser, wooden paneling, and red cushioned booths.

A reception area with a wooden reception desk, blue seating, a flat-screen TV, and a stone accent wall.

7. Comfort Inn & Suites Durham near Duke University

Croasdaile Farm Master, 3.3 km from Duke Regional Hospital

BRIAN

SAR 316

SAR 359 total

includes taxes & fees

25 Oct - 26 Oct

A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.

A bar area with a granite countertop, wooden chairs, and a large television screen.

A Hilton Garden Inn hotel with a modern design, featuring a large entrance and a parking area with a delivery van.

A business center with wooden paneling, multiple workstations, and framed artwork on the walls.

8. Hilton Garden Inn Durham/University Medical Center

9th Street District, 4 km from Duke Regional Hospital

Hal

SAR 517

SAR 587 total

includes taxes & fees

2 Nov - 3 Nov

A modern hotel reception area with two wooden reception desks, a large digital display wall, and a seating area with chairs.

A modern restaurant with bar seating, a Starbucks sign, and a bar area with a counter and shelves.

A modern lobby with a fireplace, seating area, and wooden wall accents.

A hotel room with two beds, a desk, and a chair.

9. Hilton Durham near Duke University

5.4 km from Duke Regional Hospital

tigist

SAR 428

SAR 486 total

includes taxes & fees

18 Oct - 19 Oct

An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.

A reception area with two wooden reception desks, a potted plant, and a computer on the wall.

A hotel room with two beds, a desk, a chair, a TV, and a bathroom.

10. Courtyard Raleigh-Durham Airport/Brier Creek

16.6 km from Duke Regional Hospital

eidy

SAR 507

SAR 575 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor seating area with wicker furniture and a stone fire pit.

A modern hotel lobby with seating areas, large windows, and a dining section.

A conference room with a long table, chairs, and a modern chandelier.

11. Residence Inn Raleigh-Durham Airport/Brier Creek

16.6 km from Duke Regional Hospital

Janet

SAR 523

SAR 593 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.

A modern living room with a fireplace, two sofas, a coffee table, and a TV mounted on the wall.

A multi-story hotel with a brick facade, large windows, and a well-lit entrance.

A hotel room with two beds, a desk, a chair, a sofa, and a TV.

12. Fairfield by Marriott Inn & Suites Durham

18.2 km from Duke Regional Hospital

Yolanda

SAR 446

SAR 506 total

includes taxes & fees

25 Oct - 26 Oct

A swimming pool with lounge chairs and a wooden fence.

A modern bar area with a refrigerated display, wooden bar counter, and seating.

A hotel room with a bed, a sofa, a desk with a chair, a television, and a painting on the wall.

A spacious lobby with a reception desk, seating area, and artwork on the walls.

13. Hyatt Place Durham Southpoint

16.1 km from Duke Regional Hospital

Stephen

SAR 507

SAR 575 total

includes taxes & fees

21 Oct - 22 Oct

A modern living room with a sectional sofa, a bar area, and a dining space.

A modern dining area with a central bar, multiple seating options, and geometric pendant lighting.

A modern hotel room with a large window, a sofa, a chair, and a coffee table with a decorative bowl.

A bar area with multiple shelves of liquor bottles and glasses, a marble countertop, and a bar stool.

14. AC Hotel Durham

5.4 km from Duke Regional Hospital

todd

SAR 585

SAR 664 total

includes taxes & fees

22 Oct - 23 Oct

A hotel room with two beds, a nightstand with a lamp, and a window with a view of trees.

An outdoor seating area with tables and chairs, a paved walkway, and a fence.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A gym with treadmills, elliptical machines, and exercise bikes.

15. Holiday Inn Express & Suites Raleigh Airport - Brier Creek by IHG

16.9 km from Duke Regional Hospital

Sharon

SAR 428

SAR 503 total

includes taxes & fees

8 Nov - 9 Nov

A long, narrow hallway with dark walls and wooden flooring.

A hotel room with a large bed, two bedside lamps, a chair, a desk, a heater, and a window with curtains.

A compact kitchenette with a refrigerator, microwave, and a flat-screen TV on a dark cabinet.

16. University Inn Durham next to Duke University Medical Center

4.5 km from Duke Regional Hospital

Nicole

SAR 453

SAR 514 total

includes taxes & fees

18 Oct - 19 Oct

A lobby with a bar area, seating, and a wine display.

A covered outdoor dining area with tables set for a meal, surrounded by chairs, and overlooking a garden with blooming trees.

A bar area with seating, a bar counter, and a menu board.

A large, white, two-story building with a prominent sign reading "DoubleTree".

17. DoubleTree Raleigh Durham Airport at Research Triangle Park

17.7 km from Duke Regional Hospital

Xueqin

SAR 411

SAR 467 total

includes taxes & fees

31 Oct - 1 Nov

An outdoor patio with a stone fire pit surrounded by wicker furniture and a large window overlooking the building.

A swimming pool with lounge chairs and a building with balconies in the background.

A modern living room with a fireplace, comfortable seating, and a large window offering a view of the outdoors.

A modern bar area with a curved counter, bar stools, a coffee machine, and a refrigerated display of beverages.

18. Courtyard Durham Near Duke University/Downtown

Croasdaile Farm Master, 3.5 km from Duke Regional Hospital

Billy

SAR 296

SAR 336 total

includes taxes & fees

18 Oct - 19 Oct

A multi-story hotel with a prominent "HOME 2" sign, a brick facade, and a well-lit entrance.

A modern indoor space with multiple seating areas, including tables and chairs, a television, and decorative shelves.

19. Home2 Suites by Hilton Durham University Medical Center

5 km from Duke Regional Hospital

katey

SAR 539

SAR 612 total

includes taxes & fees

18 Oct - 19 Oct

A modern hotel with a prominent entrance, multiple floors, and a balcony on the second floor.

A modern dining area with wooden tables and chairs, large windows, and geometric pendant lighting.

An outdoor patio with a fire feature, seating, and a building with large windows.

A modern hotel room with a bed, a desk, a chair, a small seating area, and a kitchenette.

20. SpringHill Suites by Marriott Durham City View

5.4 km from Duke Regional Hospital

Taurean

SAR 482

SAR 547 total

includes taxes & fees

1 Nov - 2 Nov

View all properties

Compare popular hotels close to Duke Regional Hospital

Property	Property class	Guest rating
Hampton Inn & Suites Durham/North I-85	9.0 Wonderful 1,000 reviews	View
Holiday Inn Express Durham by IHG	8.8 Excellent 1,000 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	6.8 1,000 reviews	View
La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill	8.6 Excellent 1,981 reviews	View
Hampton Inn & Suites Durham University Medical Center	9.6 Exceptional 571 reviews	View

Top Duke Regional Hospital Hotel Reviews

Millennium Hotel Durham

10/10 Excellent

"Staff very friendly and helpful Thankyou Patrick and all of the staff. Comfy beds and atmosphere"

Courtyard Durham Near Duke University/Downtown

10/10 Excellent

"Great room, close to downtown. Wonderfully professional staff. Would stay there again."

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

10/10 Excellent

"The house was absolutely immaculate and Kristin could not have nicer or more helpful. The location was just 25 minutes from RDU, 12 minutes from downtown Durham and about a half an hour from Chapel Hill. Comfortable living room for my small group, large screen TV with all the streaming channels and a very cool coffee grinder/maker for regular or espresso coffee. Highly recommend. John L"

Drexall Haven - Stylish + Peaceful Stay

8/10 Good

"The house is newly renovated so everything looks really nice. The only issue I have is a lack of dressers for our clothes. Otherwise the experience was great. Quiet neighborhood out of the way but accessible."

Everything within 1 mile

10/10 Excellent

"Perfect size and great location! The host has thought of everything and included so many extra thoughtful touches! So close to everything, quiet, clean, and stocked!"

Cottage with Yard, Mins to Duke

10/10 Excellent

"This was a cheerful home with comfortable beds and many thoughtful extras. We enjoyed our time here."

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

10/10 Excellent

"!"

Not Your Average Stay” +Glow Room by 9th St, Duke, Alexa,Games & WiFi + NEW! 2bd

10/10 Excellent

"We loved it! Rooms were large and well decorated, everything was so cute! We played football in the yard and lots of other games. The neighborhood is really nice and safe too. Lots of kids and families. I would definitely stay again!"

Tiny Home a fantastic Location close to 9th Street!

10/10 Excellent

"Loved the space it was very cozy and cute"

Frequently asked questions

What's the area like around Duke Regional Hospital?

Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Duke Regional Hospital?

Courtyard Durham Near Duke University/Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 2.2 mi (3.5 km) from Duke Regional Hospital. Other good choices within a few miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.

How many hotels can I expect to find near Duke Regional Hospital?

Expedia has 10 hotels and other accommodations within a mile from Duke Regional Hospital.

If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?

Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.

Where can I learn more about changing or cancelling my trip in the area near Duke Regional Hospital?

To find more details about changing or cancelling your stay near Duke Regional Hospital, click here.

What can I see and do near Duke Regional Hospital?

You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Find hotels near Duke Regional Hospital, Raleigh from SAR 274

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Duke Regional Hospital hotels

1. Hampton Inn & Suites Durham/North I-85

2. Holiday Inn Express Durham by IHG

3. Red Roof Inn Durham - Duke Univ Medical Center

4. La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

5. Hampton Inn & Suites Durham University Medical Center

6. DoubleTree Suites by Hilton Raleigh - Durham

7. Comfort Inn & Suites Durham near Duke University

8. Hilton Garden Inn Durham/University Medical Center

9. Hilton Durham near Duke University

10. Courtyard Raleigh-Durham Airport/Brier Creek

11. Residence Inn Raleigh-Durham Airport/Brier Creek

12. Fairfield by Marriott Inn & Suites Durham

13. Hyatt Place Durham Southpoint

14. AC Hotel Durham

15. Holiday Inn Express & Suites Raleigh Airport - Brier Creek by IHG

16. University Inn Durham next to Duke University Medical Center

17. DoubleTree Raleigh Durham Airport at Research Triangle Park

18. Courtyard Durham Near Duke University/Downtown

19. Home2 Suites by Hilton Durham University Medical Center

20. SpringHill Suites by Marriott Durham City View

Compare popular hotels close to Duke Regional Hospital

Top Duke Regional Hospital Hotel Reviews

Millennium Hotel Durham

Courtyard Durham Near Duke University/Downtown

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

Drexall Haven - Stylish + Peaceful Stay

Everything within 1 mile

Cottage with Yard, Mins to Duke

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

Not Your Average Stay” +Glow Room by 9th St, Duke, Alexa,Games & WiFi + NEW! 2bd

Tiny Home a fantastic Location close to 9th Street!

Frequently asked questions