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Find 5 Star Hotels in South San Francisco, CA from SAR165

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Compare South San Francisco 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in South San Francisco.
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

335 Powell Street, San Francisco, CA
The price is SAR165 per night from Jul 1 to Jul 2
SAR165
per night
Jul 1 - Jul 2
8.8/10 Excellent! (2,741 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 5-star hotels in South San Francisco?
The St. Regis San Francisco, Four Seasons Hotel San Francisco and Mansion on Sutter are among the best 5-star hotels in South San Francisco, according to our traveler reviews. These upscale hotels rate highly for things like their location, conveniences and guest services. Pick your favorite and experience the best of everything.
How much does it cost to stay in a 5-star hotel in South San Francisco?
The amount you pay for a 5-star hotel in South San Francisco depends on things such as when you plan to go and the length of your break. Our insider tip for bagging the best deal? Use our pricing filters to compare the available hotels for your chosen dates.

  • Search for the lowest price per night from SAR165

What makes a hotel 5 stars in South San Francisco?
In South San Francisco, a hotel must provide a certain number of upscale amenities to be designated 5 stars. These may include on-site gyms, saunas and spas, gourmet restaurants, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their outstanding standard of service. You can look forward to things like concierge services, in-room massages and nightly turn-down services. Some may also offer thoughtful touches like welcome gifts.
Are there any 5-star all-inclusive resorts in South San Francisco?
Find an indulgent escape that includes your lodging, meals, drinks and entertainment in South San Francisco with the help of Expedia’s filter tool. Search for hotels with a 5-star rating and select the “All inclusive” filter. Make sure you check what’s included in the price. This way, you’re ready to take advantage of the many perks on offer from the moment you arrive.
What are the top 5-star spa hotels in South San Francisco?
Four Seasons Hotel San Francisco combines plush accommodations with blissful wellness therapies and experiences. Choose from a menu of facials, massages and more at this well-known 5-star spa retreat in South San Francisco.
Are there any 5-star vacation rentals in South San Francisco?
Our site doesn’t have any 5-star vacation rentals in South San Francisco. However, you will still find a few top-rated options where the only thing on your agenda will be to relax and have fun. See what’s available by searching through our vacation rentals in South San Francisco.