Photo by Ryan Coleman

Find Family Hotels in Sikeston, MO

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Sikeston Family Hotels

Top Sikeston Family Hotels

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1006)
"Will stay again"
The price is SAR 383
SAR 440 total
includes taxes & fees
20 Jul - 21 Jul
Drury Inn & Suites Sikeston, MO

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1005)
"Great place to stay with kids "
The price is SAR 354
SAR 407 total
includes taxes & fees
19 Jul - 20 Jul
Pear Tree Inn Sikeston

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1011)
"We enjoyed our stay and the breakfast was good!"
The price is SAR 330
SAR 377 total
includes taxes & fees
10 Aug - 11 Aug
Best Western Plus Sikeston

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (956)
"Room was very clean and staff was excellent!"
The price is SAR 338
SAR 381 total
includes taxes & fees
19 Jul - 20 Jul
Drury Inn & Suites Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 star property
8.2 out of 10, Very Good, (719)
"Great area, fast check in, quiet, very spacious"
The price is SAR 349
SAR 378 total
includes taxes & fees
20 Jul - 21 Jul
Comfort Suites Jackson-Cape Girardeau

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1007)
"Great staff "
The price is SAR 338
SAR 357 total
includes taxes & fees
20 Jul - 21 Jul
Drury Inn & Suites Jackson MO

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1003)
"Great place to stay. "
The price is SAR 342
SAR 386 total
includes taxes & fees
1 Aug - 2 Aug
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Dexter Inn

2.5 star property
6.8 out of 10, (305)
"I always stay here when I’m in town. Great place"
Dexter Inn

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (389)
"Very friendly and accommodating "
The price is SAR 260
SAR 289 total
includes taxes & fees
27 Jul - 28 Jul
Quality Inn Charleston - Sikeston

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1009)
"Excellent place to stay "
The price is SAR 253
SAR 286 total
includes taxes & fees
17 Jul - 18 Jul
Pear Tree Inn Cape Girardeau Near the Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What's Sikeston like for family-friendly vacations?
The welcoming destination of Sikeston is a great choice if you've been considering a vacation with the kids. The excursions, museums, and cafes are just some of the things that make this an attractive family vacation spot. Arrange a flight into Cairo, IL (CIR-Cairo Regional), which is located 23.8 mi (38.3 km) from the city center.
What's the best place to stay for a family vacation in Sikeston?
Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good option for your family trip.
How many family-friendly hotels should I expect to find in Sikeston?
Expedia has 16 hotels in Sikeston that are rated for being family-friendly.
When's the best time to book a family-friendly vacation in Sikeston?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.
What's there to see and do with your family in Sikeston?
While you and the family are vacationing in Sikeston, you might want to check out some of the attractions here such as Front Street Studio & Art Gallery, Big Oak Tree State Park, and Shawnee National Forest. Make sure you have lots of time for activities like Mississippi River and Ohio River.