The Best Hotels Closest to Sikeston Depot Museum in Sikeston for 2026

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Our top choices for Sikeston Depot Museum hotels

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

1. Fairfield Inn & Suites by Marriott Sikeston

2.4 km from Sikeston Depot Museum

Roslyn

SAR 470 total

includes taxes & fees

19 Nov - 20 Nov

2. TownePlace Suites by Marriott Sikeston

2.3 km from Sikeston Depot Museum

Mark

SAR 465 total

includes taxes & fees

19 Nov - 20 Nov

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

3. Hampton Inn Sikeston

2.3 km from Sikeston Depot Museum

Deborah

SAR 432 total

includes taxes & fees

19 Nov - 20 Nov

A conference room with a long table, multiple chairs, and a television screen on the wall.

4. Holiday Inn Express & Suites Sikeston Southwest by IHG

2.1 km from Sikeston Depot Museum

Wesley

SAR 414 total

includes taxes & fees

15 Nov - 16 Nov

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

5. Drury Inn & Suites Sikeston, MO

5.1 km from Sikeston Depot Museum

Tiffany

SAR 406 total

includes taxes & fees

15 Nov - 16 Nov

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

6. Best Western Plus Sikeston I-55

5.4 km from Sikeston Depot Museum

Shelley

SAR 311 total

includes taxes & fees

7 Dec - 8 Dec

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

5 km from Sikeston Depot Museum

Craig

SAR 285 total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

8. Comfort Inn & Suites Sikeston I-55

4.9 km from Sikeston Depot Museum

Fred

SAR 360 total

includes taxes & fees

22 Nov - 23 Nov

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

9. Days Inn and Suites by Wyndham Sikeston

5.4 km from Sikeston Depot Museum

Earl

SAR 284 total

includes taxes & fees

10 Dec - 11 Dec

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

10. Super 8 by Wyndham Sikeston/Miner Area

4.7 km from Sikeston Depot Museum

Laura

SAR 248 total

includes taxes & fees

10 Dec - 11 Dec

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

11. Country Yard Inn and Suite

5.5 km from Sikeston Depot Museum

Marianne

SAR 253 total

includes taxes & fees

12 Nov - 13 Nov

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Compare popular hotels close to Sikeston Depot Museum

Property	Property class	Guest rating
Fairfield Inn & Suites by Marriott Sikeston	3.0 star property	9.4 Exceptional 118 reviews	View
TownePlace Suites by Marriott Sikeston	3.0 star property	9.2 Wonderful 32 reviews	View
Hampton Inn Sikeston	2.5 star property	9.0 Wonderful 657 reviews	View
Holiday Inn Express & Suites Sikeston Southwest by IHG	2.5 star property	8.8 Excellent 525 reviews	View
Drury Inn & Suites Sikeston, MO	3.0 star property	9.6 Exceptional 1,002 reviews	View

Top Sikeston Depot Museum Hotel Reviews

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good

"This place is a gem for the rates they charge. The property is pretty old but well maintained and very clean. The staff is friendly and polite."

Other attractions near Sikeston Depot Museum

Central Park

7.2/10 (56 reviews)

Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants.

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Frequently asked questions

What's the area like around Sikeston Depot Museum?

Sikeston Depot Museum is located in a welcoming area of Sikeston known for its array of dining options. If you're looking for a convenient place to stay, check out the 5 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay near Sikeston Depot Museum?

Drury Inn & Suites Sikeston, MO is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. It's located 3.2 mi (5.1 km) from Sikeston Depot Museum. Other good choices within 5 miles include Hampton Inn Sikeston and Days Inn and Suites by Wyndham Sikeston.

How many hotels should I expect to find close to Sikeston Depot Museum?

Expedia has 5 hotels and other accommodations within a mile from Sikeston Depot Museum.

If I need to cancel the hotel reservation for my stay near Sikeston Depot Museum, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to get the best deals near Sikeston Depot Museum.

Where can I learn more about changing or cancelling my trip in the area near Sikeston Depot Museum?

To find more details about picking new dates or cancelling your stay near Sikeston Depot Museum, head over to our customer service page.

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Our top choices for Sikeston Depot Museum hotels

1. Fairfield Inn & Suites by Marriott Sikeston