The Best Hotels Closest to Sikeston Depot Museum in Sikeston for 2026

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Our top choices for Sikeston Depot Museum hotels

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

1. Fairfield Inn & Suites by Marriott Sikeston

2.4 km from Sikeston Depot Museum

Roslyn

SAR 431 total

includes taxes & fees

8 Nov - 9 Nov

2. TownePlace Suites by Marriott Sikeston

2.3 km from Sikeston Depot Museum

Rubin

SAR 465 total

includes taxes & fees

5 Nov - 6 Nov

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

3. Hampton Inn Sikeston

2.3 km from Sikeston Depot Museum

Deborah

SAR 406 total

includes taxes & fees

22 Nov - 23 Nov

A buffet with various food items, including omelets and baked goods, served in metal containers.

4. Holiday Inn Express & Suites Sikeston Southwest by IHG

2.1 km from Sikeston Depot Museum

Melissa

SAR 423 total

includes taxes & fees

26 Nov - 27 Nov

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

5. Drury Inn & Suites Sikeston, MO

5.1 km from Sikeston Depot Museum

Tim

SAR 406 total

includes taxes & fees

3 Nov - 4 Nov

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

6. Best Western Plus Sikeston I-55

5.4 km from Sikeston Depot Museum

Shelley

SAR 341 total

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

5 km from Sikeston Depot Museum

Craig

SAR 279 total

includes taxes & fees

29 Oct - 30 Oct

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

8. Comfort Inn & Suites Sikeston I-55

4.9 km from Sikeston Depot Museum

Fred

SAR 373 total

includes taxes & fees

18 Nov - 19 Nov

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

9. Days Inn and Suites by Wyndham Sikeston

5.4 km from Sikeston Depot Museum

David

SAR 284 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

10. Super 8 by Wyndham Sikeston/Miner Area

4.7 km from Sikeston Depot Museum

Laura

SAR 248 total

includes taxes & fees

5 Nov - 6 Nov

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

11. Country Yard Inn and Suite

5.5 km from Sikeston Depot Museum

Marianne

SAR 230 total

includes taxes & fees

30 Oct - 31 Oct

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Compare popular hotels close to Sikeston Depot Museum

Property	Property class	Guest rating
Fairfield Inn & Suites by Marriott Sikeston	3.0 star property	9.4 Exceptional 118 reviews	View
TownePlace Suites by Marriott Sikeston	3.0 star property	9.2 Wonderful 29 reviews	View
Hampton Inn Sikeston	2.5 star property	9.0 Wonderful 649 reviews	View
Holiday Inn Express & Suites Sikeston Southwest by IHG	2.5 star property	8.8 Excellent 519 reviews	View
Drury Inn & Suites Sikeston, MO	3.0 star property	9.6 Exceptional 1,001 reviews	View

Top Sikeston Depot Museum Hotel Reviews

TownePlace Suites by Marriott Sikeston

10/10 Excellent

"I liked the lobby, bar and breakfast areas. The full breakfast buffet was awesome. Super nice room with kitchenette. Staff were great."

Holiday Inn Express & Suites Sikeston Southwest by IHG

10/10 Excellent

"We had a nice overnight stay here. The sleeper/sofa was not comfortable, but very few are. It was a good selection of foods for the breakfast. We especially enjoyed the coffee machine that freshly grinds the coffee beans and brews it immediately. We also liked the style of the luggage carts. They were less bulky and easier to handle."

Hampton Inn By Hilton Dexter

10/10 Excellent

"I loved this property! They had everything I look for. Indoor pool was spotless & stocked well with towels. We enjoyed the layout of the lobby, bar & eating area with multiple big screens & gift shop with frozen food & treats for those that get a little hungry. Our room & bathroom were spacious & well designed. We travel with our pup so we were very happy with the area on 2 sides with grassy areas & dog baggy collection to keep the yard clean for all dog walkers. It was the most area I’ve seen allocated for guest’s pets."

Other attractions near Sikeston Depot Museum

Central Park

7.2/10 (56 reviews)

Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants.

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Frequently asked questions

What's the area like around Sikeston Depot Museum?

Sikeston Depot Museum is located in a welcoming area of Sikeston known for its array of dining options. If you're looking for a convenient place to stay, check out the 5 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay near Sikeston Depot Museum?

Drury Inn & Suites Sikeston, MO is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. It's located 3.2 mi (5.1 km) from Sikeston Depot Museum. Other good choices within 5 miles include Hampton Inn Sikeston and Days Inn and Suites by Wyndham Sikeston.

How many hotels should I expect to find close to Sikeston Depot Museum?

Expedia has 5 hotels and other accommodations within a mile from Sikeston Depot Museum.

If I need to cancel the hotel reservation for my stay near Sikeston Depot Museum, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to get the best deals near Sikeston Depot Museum.

Where can I learn more about changing or cancelling my trip in the area near Sikeston Depot Museum?

To find more details about picking new dates or cancelling your stay near Sikeston Depot Museum, head over to our customer service page.

Find hotels near Sikeston Depot Museum, Sikeston from SAR 230

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Our top choices for Sikeston Depot Museum hotels

1. Fairfield Inn & Suites by Marriott Sikeston

2. TownePlace Suites by Marriott Sikeston

3. Hampton Inn Sikeston

4. Holiday Inn Express & Suites Sikeston Southwest by IHG

5. Drury Inn & Suites Sikeston, MO

6. Best Western Plus Sikeston I-55

7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8. Comfort Inn & Suites Sikeston I-55

9. Days Inn and Suites by Wyndham Sikeston

10. Super 8 by Wyndham Sikeston/Miner Area

11. Country Yard Inn and Suite

Compare popular hotels close to Sikeston Depot Museum

Top Sikeston Depot Museum Hotel Reviews

TownePlace Suites by Marriott Sikeston

Other attractions near Sikeston Depot Museum

Central Park

Frequently asked questions