Photo by Ryan Coleman

Find hotels in Sikeston, MO from SAR 200

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Compare 272 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Sikeston hotels

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1002)
"The pool the happy hour was really nice very relaxed nice activities front desk was very helpful at all times"
The price is SAR 394
SAR 453 total
includes taxes & fees
7 Oct - 8 Oct
Drury Inn & Suites Sikeston, MO

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1002)
"Clean and friendly staff "
The price is SAR 289
SAR 332 total
includes taxes & fees
14 Sep - 15 Sep
Pear Tree Inn Sikeston

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (384)
"I liked everything about this property this is where i stay every time im in town "
The price is SAR 401
SAR 454 total
includes taxes & fees
28 Sep - 29 Sep
Hampton Inn Sikeston

Days Inn and Suites by Wyndham Sikeston

2.0 star property
7.2 out of 10, Good, (1002)
"The room was awesome and the building had a historical thing about it."
The price is SAR 236
SAR 269 total
includes taxes & fees
8 Sep - 9 Sep
Days Inn and Suites by Wyndham Sikeston

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1002)
"Staff was friendly and room was very clean. A very comfortable stay"
The price is SAR 316
SAR 360 total
includes taxes & fees
14 Sep - 15 Sep
Best Western Plus Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
8.6 out of 10, Excellent, (426)
"Close in eating and shopping "
The price is SAR 394
SAR 446 total
includes taxes & fees
3 Oct - 4 Oct
Holiday Inn Express & Suites Sikeston Southwest by IHG

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
8.4 out of 10, Very Good, (674)
"Everything was nice"
The price is SAR 200
SAR 228 total
includes taxes & fees
8 Sep - 9 Sep
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Super 8 by Wyndham Sikeston/Miner Area

2.0 star property
6.6 out of 10, (553)
"I enjoyed our stay"
The price is SAR 230
SAR 262 total
includes taxes & fees
5 Oct - 6 Oct
Super 8 by Wyndham Sikeston/Miner Area

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
9.4 out of 10, Exceptional, (20)
"Nice hotel "
The price is SAR 379
SAR 429 total
includes taxes & fees
14 Sep - 15 Sep
Fairfield Inn & Suites by Marriott Sikeston

Country Yard Inn and Suite

2.0 star property
6.8 out of 10, (108)
"The property was well kept but lacked convenience of food and computer."
The price is SAR 211
SAR 251 total
includes taxes & fees
8 Sep - 9 Sep
Country Yard Inn and Suite

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1002)
"Employees were extremely helpful and happy to help!"
The price is SAR 338
SAR 357 total
includes taxes & fees
11 Sep - 12 Sep
Drury Inn & Suites Jackson MO

Comfort Inn & Suites Sikeston I-55

2.5 star property
8.4 out of 10, Very Good, (271)
"The facility was very nice. "
The price is SAR 335
SAR 382 total
includes taxes & fees
10 Sep - 11 Sep
Comfort Inn & Suites Sikeston I-55

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (610)
"Excellent place to stay. Breakfast was good and staff was friendly. "
The price is SAR 316
SAR 342 total
includes taxes & fees
9 Sep - 10 Sep
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

TownePlace Suites by Marriott Sikeston

3.0 star property
8.0 out of 10, Very Good, (4)
"I loved all of what this property had to offer "
The price is SAR 488
SAR 552 total
includes taxes & fees
14 Sep - 15 Sep
TownePlace Suites by Marriott Sikeston

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1003)
"Great place to stay. Safe and quiet indoors and close to get in the road again tomorrow. Staff was friendly! "
The price is SAR 263
SAR 296 total
includes taxes & fees
8 Sep - 9 Sep
Pear Tree Inn Cape Girardeau West

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (988)
"The staff was beyond friendly, the free breakfast did not disappointed, and we were just genuinely happy with our stay."
The price is SAR 338
SAR 381 total
includes taxes & fees
13 Sep - 14 Sep
Drury Inn & Suites Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1003)
"Very nice hotel and nice staff "
The price is SAR 338
SAR 381 total
includes taxes & fees
14 Sep - 15 Sep
Drury Plaza Hotel Cape Girardeau Conference Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1001)
"Excellent place to stay "
The price is SAR 263
SAR 296 total
includes taxes & fees
11 Sep - 12 Sep
Pear Tree Inn Cape Girardeau Near the Medical Center

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1002)
"The hotel was very nice and the staff were super helpful. I would stay here again!"
The price is SAR 386
SAR 436 total
includes taxes & fees
14 Sep - 15 Sep
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (409)
"From the moment we walked in we were impressed with the customer service, facility & cleanliness. We enjoyed every part of our one night stay! We would definitely stay here again "
The price is SAR 395
SAR 446 total
includes taxes & fees
8 Sep - 9 Sep
The Riverview
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Sikeston attractions

Sikeston Depot Museum

Sikeston Depot Museum

You can spend time exploring the galleries in Sikeston Depot Museum in Sikeston. While in this relaxing area, you can savor the top-notch restaurants.

Central Park

Central Park

Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants.

Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

The best restaurant I have EVER been to! Hands down!!!
Photo by Ryan Coleman
Open Photo by Ryan Coleman

Top Sikeston Hotel Reviews

More cheap stays in Sikeston

More cheap stays in Sikeston

Hotels in Sikeston with star-rating

Hotels in Sikeston with star-rating

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

Where is the best place to stay in Sikeston?

Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Hampton Inn Sikeston. See all available top hotels, or vacation rentals in Sikeston.

What are some of the best vacation rentals in Sikeston?

* On the Wine Trail * Hot Tub * Wi-Fi *: This vacation home rental outside of Sikeston is located on a lake and has a patio, a hot tub, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Sikeston.

If I need to cancel my hotel reservation in Sikeston, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.

Where can I learn more about changing or cancelling my trip to Sikeston?

For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.

What's the best budget-friendly hotel in Sikeston?

Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Sikeston.

What's the best hotel for a family vacation in Sikeston?

Pear Tree Inn Sikeston is a hotel with an outdoor pool and free breakfast, and it's a top choice on Expedia for families. Drury Inn & Suites Sikeston, MO is another good choice for your stay with the kids. Find more child-friendly accommodations in Sikeston.

What is the top LGBTQ-friendly hotel in Sikeston?

Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Pear Tree Inn Sikeston and Hampton Inn Sikeston are two other good options for your vacation.

What's the best pet-friendly accommodation in Sikeston?

Pear Tree Inn Sikeston is a top hotel for people traveling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good options for you and your pet's trip include Drury Inn & Suites Sikeston, MO and Best Western Plus Sikeston. See more pet-friendly hotel accommodations in Sikeston.

Where is the best hotel to stay close to Central Park?

Hampton Inn Sikeston is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.6 km) from Central Park. Another good option is Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel, located just 0.9 mi (1.5 km) away.

What about the best place to stay close to Sikeston Depot Museum?

One of the top choices for your stay is Pear Tree Inn Sikeston, located 3.1 mi (5 km) from Sikeston Depot Museum, and this hotel offers free breakfast and an outdoor pool. Hampton Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options within a few miles.

What are some accommodations with pools in Sikeston?

Best Western Plus Sikeston is a top hotel with a pool, free full breakfast, and free parking. TownePlace Suites by Marriott Sikeston is one more option that features an onsite pool. View all hotels with pools in Sikeston.

What's the best place to stay near Barkley Regional Airport (PAH)?

Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.

What is staying in Sikeston like?

Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodations to choose from. Find out more about Sikeston.

What are the top places to visit in Sikeston?

A couple of favorite places to visit are Sikeston Depot Museum and Central Park. You'll also find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery in the area. Check out what more to see and do in Expedia's Sikeston guide.

What's the seasonal weather like in Sikeston?

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.