Photo by Ryan Coleman

Find hotels in Sikeston, MO from SAR 219

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Compare 262 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1003)
"Convenient location, clean and friendly staff."
The price is SAR 353
SAR 405 total
includes taxes & fees
6 Jul - 7 Jul
Drury Inn & Suites Sikeston, MO

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1005)
"We enjoyed our stay and the breakfast was good!"
The price is SAR 334
SAR 380 total
includes taxes & fees
29 Jun - 30 Jun
Best Western Plus Sikeston

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1004)
"Great place to stay with kids "
The price is SAR 405
SAR 466 total
includes taxes & fees
6 Jul - 7 Jul
Pear Tree Inn Sikeston

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (357)
"Clean, great breakfast, quiet, friendly staff"
The price is SAR 443
SAR 502 total
includes taxes & fees
20 Jul - 21 Jul
Hampton Inn Sikeston

Days Inn and Suites by Wyndham Sikeston

2.0 star property
7.2 out of 10, Good, (1002)
"We were there to get a good nights sleep and we did."
The price is SAR 303
SAR 345 total
includes taxes & fees
29 Jun - 30 Jun
Days Inn and Suites by Wyndham Sikeston

Country Yard Inn and Suite

2.0 star property
7.2 out of 10, Good, (95)
"Nice place excellent service "
The price is SAR 243
SAR 289 total
includes taxes & fees
29 Jun - 30 Jun
Country Yard Inn and Suite

Super 8 by Wyndham Sikeston/Miner Area

2.0 star property
6.6 out of 10, (538)
"I enjoyed our stay"
The price is SAR 249
SAR 284 total
includes taxes & fees
6 Jul - 7 Jul
Super 8 by Wyndham Sikeston/Miner Area

Comfort Inn & Suites Sikeston I-55

2.5 star property
8.4 out of 10, Very Good, (263)
"The facility was very nice. "
The price is SAR 354
SAR 404 total
includes taxes & fees
29 Jun - 30 Jun
Comfort Inn & Suites Sikeston I-55

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1002)
"Great breakfast!"
The price is SAR 321
SAR 339 total
includes taxes & fees
2 Jul - 3 Jul
Drury Inn & Suites Jackson MO

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
8.4 out of 10, Very Good, (659)
"Property is always clean, rooms are nice."
The price is SAR 238
SAR 271 total
includes taxes & fees
1 Jul - 2 Jul
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

TownePlace Suites by Marriott Sikeston

3.0 star property
4.0 out of 10, (1)
TownePlace Suites by Marriott Sikeston

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (576)
"Love the outdoor patio and the inside living room area for people to come visit you at the hotel "
The price is SAR 316
SAR 342 total
includes taxes & fees
3 Jul - 4 Jul
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1000)
"Front desk staff was very friendly and helpful."
The price is SAR 270
SAR 305 total
includes taxes & fees
1 Jul - 2 Jul
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1001)
"Great area. Great value"
The price is SAR 219
SAR 247 total
includes taxes & fees
1 Jul - 2 Jul
Pear Tree Inn Cape Girardeau Near the Medical Center

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1003)
"We were very pleased with this Drury Inn will definitely stay here again "
The price is SAR 338
SAR 381 total
includes taxes & fees
1 Jul - 2 Jul
Drury Plaza Hotel Cape Girardeau Conference Center

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1000)
"Great place to stay. "
The price is SAR 413
SAR 465 total
includes taxes & fees
18 Jul - 19 Jul
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (948)
"Room was very clean and staff was excellent!"
The price is SAR 354
SAR 400 total
includes taxes & fees
1 Jul - 2 Jul
Drury Inn & Suites Cape Girardeau

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (307)
"Enjoyed our stay and the Casino"
The price is SAR 395
SAR 446 total
includes taxes & fees
29 Jun - 30 Jun
The Riverview

Dexter Inn

2.5 star property
6.8 out of 10, (303)
"I always stay here when I’m in town. Great place"
The price is SAR 259
SAR 291 total
includes taxes & fees
29 Jun - 30 Jun
Dexter Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

The best restaurant I have EVER been to! Hands down!!!
Photo by Ryan Coleman
Open Photo by Ryan Coleman

Frequently asked questions

Where is the best place to stay in Sikeston?

Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest by IHG. See all available top hotels, or vacation rentals in Sikeston.

What are some of the best vacation rentals in Sikeston?

Beautiful location in the secluded woods : This vacation home rental outside of Sikeston offers a fireplace, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind. See all vacation rentals in Sikeston.

If I need to cancel my hotel reservation in Sikeston, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.

Where can I learn more about changing or cancelling my trip to Sikeston?

For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.

What's the best budget-friendly hotel in Sikeston?

Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Sikeston.

What's the best hotel for a family vacation in Sikeston?

Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your stay with the kids. Find more child-friendly accommodations in Sikeston.

What is the top LGBTQ-friendly hotel in Sikeston?

Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Pear Tree Inn Sikeston and Hampton Inn Sikeston are two other good options for your vacation.

What's the best pet-friendly accommodation in Sikeston?

Drury Inn & Suites Sikeston, MO is a top hotel for people traveling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good options for you and your pet's trip include Pear Tree Inn Sikeston and Best Western Plus Sikeston. See more pet-friendly hotel accommodations in Sikeston.

Where is the best hotel to stay close to Central Park?

Hampton Inn Sikeston is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.6 km) from Central Park. Another good option is Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel, located just 0.9 mi (1.5 km) away.

What about the best place to stay close to Sikeston Depot Museum?

One of the top choices for your stay is Pear Tree Inn Sikeston, located 3.1 mi (5 km) from Sikeston Depot Museum, and this hotel offers free breakfast and an outdoor pool. Hampton Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options within a few miles.

What are some accommodations with pools in Sikeston?

Best Western Plus Sikeston is a top hotel with a pool, free full breakfast, and free parking. TownePlace Suites by Marriott Sikeston is one more option that features an onsite pool. View all hotels with pools in Sikeston.

What's the best place to stay near Barkley Regional Airport (PAH)?

Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.

What is staying in Sikeston like?

Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodations to choose from. Find out more about Sikeston.

What are the top places to visit in Sikeston?

A couple of favorite places to visit are Sikeston Depot Museum and Central Park. You'll also find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery in the area. Check out what more to see and do in Expedia's Sikeston guide.

What's the seasonal weather like in Sikeston?

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.