Photo by Ryan Coleman

Find hotels in Sikeston, MO from SAR 255

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Compare 263 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1005)
"Will stay again"
The price is SAR 383
SAR 440 total
includes taxes & fees
21 Aug - 22 Aug
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (962)
"Love the property. Staff is always amazing."
The price is SAR 338
SAR 381 total
includes taxes & fees
27 Jul - 28 Jul
Drury Inn & Suites Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1006)
"Great place to stay. "
The price is SAR 364
SAR 411 total
includes taxes & fees
22 Aug - 23 Aug
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1011)
"The staff was very friendly and the hotel was very clean!"
The price is SAR 338
SAR 381 total
includes taxes & fees
10 Aug - 11 Aug
Drury Plaza Hotel Cape Girardeau Conference Center

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (728)
"Close distance to good restaurants "
The price is SAR 411
SAR 464 total
includes taxes & fees
1 Aug - 2 Aug
Hampton Inn Cape Girardeau I 55 East

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
9.8 out of 10, Exceptional, (15)
"Nice hotel "
The price is SAR 446
SAR 505 total
includes taxes & fees
24 Jul - 25 Jul
Fairfield Inn & Suites by Marriott Sikeston

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (585)
"I liked that it was quiet and breakfast was good."
The price is SAR 316
SAR 342 total
includes taxes & fees
27 Jul - 28 Jul
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (355)
"Wonderful place to stay. Very clean and affordable!"
The price is SAR 395
SAR 446 total
includes taxes & fees
27 Jul - 28 Jul
The Riverview

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1006)
"We enjoyed the quick check in and how quiet the property was. "
The price is SAR 263
SAR 296 total
includes taxes & fees
28 Jul - 29 Jul
Pear Tree Inn Cape Girardeau West

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (114)
"Hotel was very clean and the lady that checked us in was very friendly. "
The price is SAR 349
SAR 394 total
includes taxes & fees
21 Aug - 22 Aug
Fairfield Inn & Suites by Marriott Cape Girardeau

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (363)
"Clean, great breakfast, quiet, friendly staff"
The price is SAR 443
SAR 502 total
includes taxes & fees
1 Aug - 2 Aug
Hampton Inn Sikeston

Holiday Inn Express & Suites Perryville by IHG

2.5 star property
9.4 out of 10, Exceptional, (486)
"Good place "
The price is SAR 386
SAR 442 total
includes taxes & fees
23 Aug - 24 Aug
Holiday Inn Express & Suites Perryville by IHG

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1004)
"Great breakfast!"
The price is SAR 338
SAR 357 total
includes taxes & fees
28 Jul - 29 Jul
Drury Inn & Suites Jackson MO

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1005)
"Great place to stay with kids "
The price is SAR 300
SAR 345 total
includes taxes & fees
28 Jul - 29 Jul
Pear Tree Inn Sikeston

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 star property
9.4 out of 10, Exceptional, (455)
"Excellent stay!"
The price is SAR 390
SAR 433 total
includes taxes & fees
3 Aug - 4 Aug
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1005)
"Excellent place to stay "
The price is SAR 263
SAR 296 total
includes taxes & fees
10 Aug - 11 Aug
Pear Tree Inn Cape Girardeau Near the Medical Center

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1006)
"We enjoyed our stay and the breakfast was good!"
The price is SAR 331
SAR 377 total
includes taxes & fees
10 Aug - 11 Aug
Best Western Plus Sikeston

Super 8 by Wyndham Perryville

2.0 star property
8.4 out of 10, Very Good, (880)
"Clean and convenient location "
The price is SAR 255
SAR 292 total
includes taxes & fees
30 Jul - 31 Jul
Super 8 by Wyndham Perryville

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (430)
"Very clean and upscale hotel."
The price is SAR 469
SAR 531 total
includes taxes & fees
3 Aug - 4 Aug
Courtyard by Marriott Cape Girardeau Downtown

Tru By Hilton Cape Girardeau

2.5 star property
9.6 out of 10, Exceptional, (49)
"Great overall stay"
The price is SAR 379
SAR 432 total
includes taxes & fees
21 Aug - 22 Aug
Tru By Hilton Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Sikeston attractions

Sikeston Depot Museum

Sikeston Depot Museum

4/5(15 reviews)

You can spend time exploring the galleries in Sikeston Depot Museum in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants.

Central Park

Central Park

4/5(25 reviews)

Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants.

Sikeston and related destinations

Explore Sikeston: its food, riverfront, museums, and more!

The best restaurant I have EVER been to! Hands down!!!
Photo by Ryan Coleman
Open Photo by Ryan Coleman

Best guest reviews of Sikeston

Top Sikeston Hotel Reviews

Frequently asked questions

Where is the best place to stay in Sikeston?

Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Hampton Inn Sikeston. See all available top hotels, or vacation rentals in Sikeston.

What are some of the best vacation rentals in Sikeston?

Beautiful location in the secluded woods : This vacation home rental outside of Sikeston offers a fireplace, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind. See all vacation rentals in Sikeston.

If I need to cancel my hotel reservation in Sikeston, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.

Where can I learn more about changing or cancelling my trip to Sikeston?

For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.

What's the best budget-friendly hotel in Sikeston?

Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Sikeston.

What's the best hotel for a family vacation in Sikeston?

Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your stay with the kids. Find more child-friendly accommodations in Sikeston.

What is the top LGBTQ-friendly hotel in Sikeston?

Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Sikeston and Pear Tree Inn Sikeston are two other good options for your vacation.

What's the best pet-friendly accommodation in Sikeston?

Best Western Plus Sikeston is a top hotel for people traveling with their pets, and offers an indoor pool and a fitness center for its human guests. Other good options for you and your pet's trip include Drury Inn & Suites Sikeston, MO and Hampton Inn Sikeston. See more pet-friendly hotel accommodations in Sikeston.

Where is the best hotel to stay close to Central Park?

Hampton Inn Sikeston is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.6 km) from Central Park. Another good option is Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel, located just 0.9 mi (1.5 km) away.

What about the best place to stay close to Sikeston Depot Museum?

One of the top choices for your stay is Pear Tree Inn Sikeston, located 3.1 mi (5 km) from Sikeston Depot Museum, and this hotel offers free breakfast and an outdoor pool. Hampton Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options within a few miles.

What are some accommodations with pools in Sikeston?

Best Western Plus Sikeston is a top hotel with a pool, free full breakfast, and free parking. TownePlace Suites by Marriott Sikeston is one more option that features an onsite pool. View all hotels with pools in Sikeston.

What's the best place to stay near Barkley Regional Airport (PAH)?

Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.

What is staying in Sikeston like?

Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodations to choose from. Find out more about Sikeston.

What are the top places to visit in Sikeston?

A couple of favorite places to visit are Sikeston Depot Museum and Central Park. You'll also find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery in the area. Check out what more to see and do in Expedia's Sikeston guide.

What's the seasonal weather like in Sikeston?

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.