Find hotels in Otay Mesa, San Diego from SAR 255

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Discover 4,566 Otay Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 star property
7.8 out of 10, Good, (1397)
"Great stay, close to the Cross Border Xpress "
The price is SAR 521
SAR 593 total
includes taxes & fees
3 Jul - 4 Jul
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Quality Suites San Diego Otay Mesa

2.5 star property
7.2 out of 10, Good, (1001)
"Great rooms no hot water when I got there other than that good "
The price is SAR 390
SAR 443 total
includes taxes & fees
29 Jun - 30 Jun
Quality Suites San Diego Otay Mesa

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1343)
"I enjoyed the location and the pool area."
Sycuan Casino Resort

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.6 out of 10, Good, (1002)
"Great place!"
The price is SAR 435
SAR 480 total
includes taxes & fees
29 Jun - 30 Jun
Days Inn by Wyndham San Diego-East/El Cajon

Super 8 by Wyndham El Cajon/San Diego

2.0 star property
7.6 out of 10, Good, (1001)
"Nice staff and quiet "
The price is SAR 354
SAR 390 total
includes taxes & fees
29 Jun - 30 Jun
Super 8 by Wyndham El Cajon/San Diego

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very Good, (1003)
"Stayed here while visiting friends, best in the area and very comfortable. "
The price is SAR 462
SAR 508 total
includes taxes & fees
6 Jul - 7 Jul
Best Western Plus La Mesa San Diego

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.4 out of 10, Exceptional, (356)
"Great spot for business travelers "
The price is SAR 784
SAR 864 total
includes taxes & fees
29 Jun - 30 Jun
SpringHill Suites by Marriott Chula Vista Eastlake

Heritage Inn La Mesa

2.0 star property
6.6 out of 10, (1005)
"Small rooms but friendly staff and prime location"
The price is SAR 270
SAR 298 total
includes taxes & fees
30 Jun - 1 Jul
Heritage Inn La Mesa

Lamplighter Inn & Suites at SDSU

2.5 star property
9.2 out of 10, Wonderful, (1178)
"Nice place to stay "
Lamplighter Inn & Suites at SDSU

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
7.8 out of 10, Good, (1440)
"Good breakfast, close to concert venue, easy freeway access "
The price is SAR 443
SAR 487 total
includes taxes & fees
6 Jul - 7 Jul
Best Western Chula Vista/Otay Valley Hotel

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
8.6 out of 10, Excellent, (1258)
"Had a very nice stay."
The price is SAR 476
SAR 524 total
includes taxes & fees
29 Jun - 30 Jun
La Quinta Inn by Wyndham San Diego Chula Vista

Studio 6 Suites San Ysidro, CA -San Diego South Bay

2.5 star property
7.8 out of 10, Good, (1098)
"Clean quiet and staff is friendly!"
The price is SAR 319
SAR 363 total
includes taxes & fees
29 Jun - 30 Jun
Studio 6 Suites San Ysidro, CA -San Diego South Bay

Valli Hi Motel

2.5 star property
8.2 out of 10, Very Good, (1002)
"Affordable and near the border for convenience. "
Valli Hi Motel

Best Western Americana Inn

2.5 star property
8.8 out of 10, Excellent, (1106)
"We really enjoy this hotel, it was clean and the service was excellent."
The price is SAR 426
SAR 484 total
includes taxes & fees
6 Jul - 7 Jul
Best Western Americana Inn

Hotel Baja San Diego - A Boutique Hotel

2.5 star property
7.4 out of 10, Good, (1000)
"You have two staff that were very friendly and very helpful. One in the morning was name Laura and the other one was named Laura. And then a gentleman name Omar."
Hotel Baja San Diego - A Boutique Hotel

Chula Vista Inn

2.5 star property
6.6 out of 10, (1001)
"Nice hotel "
Chula Vista Inn

Quality Inn San Diego South - Chula Vista

2.5 star property
7.6 out of 10, Good, (969)
"Easy to get to, affordable and clean "
The price is SAR 446
SAR 491 total
includes taxes & fees
29 Jun - 30 Jun
Quality Inn San Diego South - Chula Vista

Days Inn by Wyndham Chula Vista/San Diego

2.0 star property
6.2 out of 10, (946)
"Clean easy check in, cancelled our sencond night before we arrived."
The price is SAR 351
SAR 386 total
includes taxes & fees
29 Jun - 30 Jun
Days Inn by Wyndham Chula Vista/San Diego

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1738)
"Great rooms ,Awesome staff. And pet friendly!!! "
The price is SAR 255
SAR 281 total
includes taxes & fees
29 Jun - 30 Jun
Hotel Palmeras Chula Vista

Hercor Hotel - Urban Boutique

3.0 star property
8.6 out of 10, Excellent, (1191)
"Excellent staff willing to assist and help with any questions. Most comfortable stay, I will definitely be back. "
The price is SAR 497
SAR 548 total
includes taxes & fees
28 Jul - 29 Jul
Hercor Hotel - Urban Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most.
Downtown San Diego map

Downtown San Diego

2 out of top 10 points of interest in this area

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Mission Beach map

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Pacific Beach map

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Gaslamp Quarter map

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Ocean Beach map

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach Pier and Ocean Beach, you won't get bored spending a day wandering around this part of San Diego.

Frequently asked questions

What's it like in Otay Mesa?

Otay Mesa is a neighborhood that travelers like for its beaches, restaurants, and shopping.

Where is the best hotel for a stay in Otay Mesa?

Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.

How many hotels will I be able to find in the Otay Mesa area?

Expedia has 5 Otay Mesa hotels and other accommodations, and one might make a good home base for venturing out into the greater San Diego area.

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Otay Mesa.

Where can I learn more about changing or cancelling my trip to Otay Mesa?

To find more details about changing or cancelling your trip to Otay Mesa, go to https://www.expedia.com/service/.

What is there to do in this San Diego neighborhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana, and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.