Find hotels in Medical Center District, San Antonio from SAR 155
Go beyond your typical stay in Medical Center District
Check prices for these dates
Discover 4,398 Medical Center District hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical Center

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

SpringHill Suites by Marriott San Antonio Medical Center/NW
SpringHill Suites by Marriott San Antonio Medical Center/NW

Courtyard by Marriott Medical Center San Antonio
Courtyard by Marriott Medical Center San Antonio

San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center
Where to stay in Medical Center District

Downtown San Antonio
Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Uptown
While visiting Uptown, you might make a stop by sights like San Antonio Zoo and Aquarium and San Antonio River.

Stone Oak
Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista while you're in town.

Northwest Side
While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Convocation Center.
Recent reviews of Medical Center District hotels
Recent reviews of Medical Center District hotels

Sonesta ES Suites San Antonio Downtown Alamo Plaza
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in top San Antonio neighborhoods
Hotels near popular San Antonio Attractions
- Hotels near USAA Corporate Office Headquarters
- Hotels near South Texas Medical Center
- Hotels near University of Texas Health and Science Center at San Antonio
- Hotels near CHRISTUS Santa Rosa Hospital - Medical Center
- Hotels near Oak Hills Country Club
- Hotels near The San Antonio Art Institute
- Hotels near River Walk
More Accommodation Types in
- Vacation Homes in San Antonio
- Apartments in San Antonio
- Cottages in San Antonio
- Condo Rentals in San Antonio
- Motels in San Antonio
- Villas in San Antonio
- Guest Houses in San Antonio
- Resorts in San Antonio
- B&B in San Antonio
- Aparthotels in San Antonio
- RV Parks in San Antonio
- Lodges in San Antonio
- Residences in San Antonio
- Holiday Park Resorts in San Antonio
- Inns in San Antonio
- Ranches in San Antonio
Hotels Close to Nearby Airports
Medical Center District Hotels by Star Rating
Explore more hotels
- Hyatt Place San Antonio - Riverwalk
- La Quinta Inn & Suites by Wyndham San Antonio Downtown
- Hotel Contessa
- La Quinta Inn & Suites by Wyndham San Antonio Airport
- La Quinta Inn & Suites By Wyndham San Antonio At The Rim
- Canopy by Hilton San Antonio Riverwalk
- Plaza San Antonio Hotel & Spa, Autograph Collection
- Omni La Mansion del Rio
- Grand Hyatt San Antonio River Walk
- Hyatt Regency Hill Country Resort & Spa
- Days Inn By Wyndham San Antonio Near Lackland Afb
- Days Inn by Wyndham San Antonio Alamo/Riverwalk