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Discover 4,133 Medical Center District hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.
Hotel Contessa
Hotel Contessa
8.8 out of 10, Excellent, (2738)
The price is SAR 654
SAR 809 total
includes taxes & fees
3 Jum. II - 4 Jum. II
Omni La Mansion del Rio
Omni La Mansion del Rio
9.2 out of 10, Wonderful, (2147)
The price is SAR 706
SAR 824 total
includes taxes & fees
16 Jum. II - 17 Jum. II
Grand Hyatt San Antonio River Walk
Grand Hyatt San Antonio River Walk
8.8 out of 10, Excellent, (1073)
The price is SAR 672
SAR 789 total
includes taxes & fees
27 Jum. I - 28 Jum. I
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Sonesta ES Suites San Antonio Downtown Alamo Plaza
Sonesta ES Suites San Antonio Downtown Alamo Plaza
8.4 out of 10, Very Good, (1320)
The price is SAR 388
SAR 447 total
includes taxes & fees
16 Jum. II - 17 Jum. II
Hampton Inn San Antonio-Downtown (River Walk)
Hampton Inn San Antonio-Downtown (River Walk)
8.2 out of 10, Very Good, (2618)
The price is SAR 347
SAR 401 total
includes taxes & fees
2 Jum. II - 3 Jum. II
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
8.6 out of 10, Excellent, (3011)
The price is SAR 333
SAR 394 total
includes taxes & fees
27 Jum. I - 28 Jum. I
Canopy by Hilton San Antonio Riverwalk
Canopy by Hilton San Antonio Riverwalk
9.4 out of 10, Exceptional, (1290)
The price is SAR 717
SAR 836 total
includes taxes & fees
1 Jum. II - 2 Jum. II
Tru By Hilton San Antonio Downtown Riverwalk
Tru By Hilton San Antonio Downtown Riverwalk
7.8 out of 10, Good, (1006)
The price is SAR 347
SAR 397 total
includes taxes & fees
2 Jum. II - 3 Jum. II
Holiday Inn San Antonio - Riverwalk, an IHG Hotel
Holiday Inn San Antonio - Riverwalk, an IHG Hotel
8.4 out of 10, Very Good, (1486)
The price is SAR 484
SAR 560 total
includes taxes & fees
27 Jum. I - 28 Jum. I
AC Hotel by Marriott San Antonio Riverwalk
AC Hotel by Marriott San Antonio Riverwalk
8.4 out of 10, Very Good, (249)
The price is SAR 458
SAR 527 total
includes taxes & fees
23 Jum. II - 24 Jum. II
Home2 Suites by Hilton San Antonio Downtown - Riverwalk, TX
Home2 Suites by Hilton San Antonio Downtown - Riverwalk, TX
8.0 out of 10, Very Good, (1002)
The price is SAR 475
SAR 550 total
includes taxes & fees
7 Jum. II - 8 Jum. II
Hyatt Regency Hill Country Resort & Spa
Hyatt Regency Hill Country Resort & Spa
8.8 out of 10, Excellent, (1003)
The price is SAR 1,159
SAR 1,520 total
includes taxes & fees
27 Jum. I - 28 Jum. I
O´Brien Historic Hotel
O´Brien Historic Hotel
7.8 out of 10, Good, (1005)
The price is SAR 458
SAR 520 total
includes taxes & fees
28 Jum. I - 29 Jum. I
San Antonio Marriott Rivercenter on the River Walk
San Antonio Marriott Rivercenter on the River Walk
8.8 out of 10, Excellent, (1002)
The price is SAR 728
SAR 944 total
includes taxes & fees
27 Jum. I - 28 Jum. I
Element San Antonio Riverwalk
Element San Antonio Riverwalk
8.6 out of 10, Excellent, (253)
The price is SAR 458
SAR 527 total
includes taxes & fees
2 Jum. II - 3 Jum. II
Sonesta ES Suites San Antonio Northwest - Medical Center
Sonesta ES Suites San Antonio Northwest - Medical Center
8.2 out of 10, Very Good, (1003)
The price is SAR 360
SAR 415 total
includes taxes & fees
2 Jum. II - 3 Jum. II
Aloft San Antonio UTSA Area
Aloft San Antonio UTSA Area
8.8 out of 10, Excellent, (563)
The price is SAR 315
SAR 366 total
includes taxes & fees
2 Jum. II - 3 Jum. II
Comfort Inn and Suites Near Medical Center
Comfort Inn and Suites Near Medical Center
7.2 out of 10, Good, (505)
The price is SAR 236
SAR 269 total
includes taxes & fees
2 Jum. II - 3 Jum. II
SpringHill Suites San Antonio Downtown/Riverwalk Area
SpringHill Suites San Antonio Downtown/Riverwalk Area
8.2 out of 10, Very Good, (1005)
The price is SAR 411
SAR 481 total
includes taxes & fees
2 Jum. II - 3 Jum. II
Home2 Suites by Hilton San Antonio Riverwalk, TX
Home2 Suites by Hilton San Antonio Riverwalk, TX
8.6 out of 10, Excellent, (1003)
The price is SAR 529
SAR 608 total
includes taxes & fees
29 Jum. I - 30 Jum. I
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Other neighborhoods around Medical Center District
Hotels in top San Antonio neighborhoods Learn more about Medical Center District
Downtown San Antonio
3 out of top 10 points of interest in this area
4/5(9,525 area reviews)
The stunning river views and popular shops are just a few highlights of Downtown San Antonio. Make a stop by Alamo or Alamodome while you're exploring the area.
Frequently asked questions
Recent reviews of Medical Center District hotels
5/5 Excellent
"Great place to stay!! Clean and convenient. "
A verified traveler stayed at Grand Hyatt San Antonio River Walk
Posted 11 hours ago
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Hotels Close to Nearby Airports
Medical Center District Hotels by Star Rating
Medical Center District Hotels by Brand
- Benchmark Hotels (2)
- Best Western Hotels (6)
- Drury Inn & Suites Hotels (7)
- Hilton Hotels Hotels (2)
- Independent Hotels (2426)
- La Quinta Inn & Suites Hotels (16)
- Marriott Hotels & Resorts Hotels (4)
- Motel 6 Hotels (16)
- Omni Hotels (2)
- Red Lion Hotels (2)
- Red Roof Inn Hotels (4)
- Wyndham Extra Holidays Hotels (2)
Explore more hotels
- Hyatt Regency San Antonio Riverwalk
- Canopy by Hilton San Antonio Riverwalk
- Drury Plaza Hotel San Antonio Airport
- Drury Plaza Hotel San Antonio Riverwalk
- Hotel Valencia Riverwalk
- Omni La Mansion del Rio
- Grand Hyatt San Antonio River Walk
- JW Marriott San Antonio Hill Country Resort & Spa
- Hyatt Vacation Club at Wild Oak Ranch, San Antonio
- La Quinta Inn by Wyndham San Antonio I-35 N at Toepperwein
- The Westin Riverwalk, San Antonio
- La Quinta Inn & Suites by Wyndham San Antonio Downtown