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Find 5 Star Hotels in Medical Center District, TX from SAR197
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Compare Medical Center District 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
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Medical Center District Hotels by Star Rating
Hotels in Medical Center District Neighborhoods
Stay near popular Medical Center District attractions
- USAA Corporate Office Headquarters
- South Texas Medical Center
- CHRISTUS Santa Rosa Hospital - Medical Center
- University of Texas Health and Science Center at San Antonio
- Oak Hills Country Club
- The San Antonio Art Institute
- Six Flags Fiesta Texas
- Lackland Air Force Base
- Alamo
- River Walk
- Alamodome
- San Antonio Zoo and Aquarium
- Frost Bank Center
- Henry B. González Convention Center
- The Shops of La Cantera
- The Rim Shopping Center
- San Antonio River
Explore more hotels
- Hotel Contessa
- Hotel Gibbs Downtown Riverwalk
- Hotel Valencia Riverwalk
- Omni La Mansion del Rio
- Drury Plaza Hotel San Antonio Riverwalk
- Spark By Hilton San Antonio Northwest near Six Flags
- Hyatt Regency San Antonio Riverwalk
- Canopy by Hilton San Antonio Riverwalk
- Drury Plaza Hotel San Antonio Airport
- JW Marriott San Antonio Hill Country Resort & Spa
- Grand Hyatt San Antonio River Walk
- Crockett Hotel
- La Quinta Inn by Wyndham San Antonio I-35 N at Toepperwein
- Homewood Suites by Hilton San Antonio Riverwalk/Downtown
- Hyatt Vacation Club at Wild Oak Ranch, San Antonio
- La Quinta Inn & Suites by Wyndham San Antonio Downtown
- Embassy Suites by Hilton San Antonio Airport
- The Westin Riverwalk, San Antonio
- Hampton Inn & Suites San Antonio Northwest/Medical Center
- The Gunter Hotel San Antonio Riverwalk