Find Luxury Hotels in Florence, SC

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Check availability on Florence Luxury Hotels

Compare Florence Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

The Mantissa Hotel

3.0 star property
9.2 out of 10, Wonderful, (235)
"Great hotel! I always stay here for my trips to Hartsville!!!"
The price is SAR 638
SAR 715 total
includes taxes & fees
12 Jun - 13 Jun
The Mantissa Hotel

Days Inn by Wyndham Dillon

2.0 star property
5.4 out of 10, (783)
"Location is perfect, right beside the 95… and lots of choices of restaurants."
The price is SAR 236
SAR 264 total
includes taxes & fees
2 Jun - 3 Jun
Days Inn by Wyndham Dillon

Hotel Florence, Tapestry Collection by Hilton

3.0 star property
8.8 out of 10, Excellent, (572)
"Victors is a great restaurant in the hotel."
The price is SAR 497
SAR 557 total
includes taxes & fees
15 Jun - 16 Jun
Hotel Florence, Tapestry Collection by Hilton

Days Inn by Wyndham Florence/I-95 North

2.0 star property
6.8 out of 10, (1000)
"For the price its a great stay!"
The price is SAR 223
SAR 250 total
includes taxes & fees
15 Jun - 16 Jun
Days Inn by Wyndham Florence/I-95 North

Baymont Inn & Suites Florence by Wyndham

2.5 star property
5.6 out of 10, (1000)
"good to stay "
Baymont Inn & Suites Florence by Wyndham

Clarion Inn & Suites

2.5 star property
4.4 out of 10, (266)
"Had stayed there before still sorry"
The price is SAR 203
SAR 227 total
includes taxes & fees
30 Jun - 1 Jul
Clarion Inn & Suites

Red Roof Inn Florence - Civic Center

2.0 star property
6.8 out of 10, (1002)
"Nice stay thanks"
The price is SAR 239
SAR 267 total
includes taxes & fees
3 Jun - 4 Jun
Red Roof Inn Florence - Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 star property
6.8 out of 10, (1003)
"My stay was comfortable with no complaints!"
The price is SAR 239
SAR 268 total
includes taxes & fees
1 Jun - 2 Jun
Days Inn by Wyndham Florence Near Civic Center

Quality Inn & Suites

2.5 star property
7.4 out of 10, Good, (682)
"Young lady at front desk was very polite and helpful "
The price is SAR 283
SAR 317 total
includes taxes & fees
30 Jun - 1 Jul
Quality Inn & Suites

Quality Inn & Suites Florence Civic Center

2.5 star property
7.8 out of 10, Good, (1214)
"Great place to stay"
The price is SAR 327
SAR 366 total
includes taxes & fees
29 Jun - 30 Jun
Quality Inn & Suites Florence Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Florence?
Expedia can help you get a flight to Florence, SC (FLO-Florence Regional) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you’d like to make your stay special. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Florence offers. During your visit, you might want to enjoy the shopping which Florence is known for.
How many luxury hotels will I be able to find in Florence?
Lie in the lap of luxury during your getaway to Florence in one of Expedia’s 20 luxury hotels.
When can I expect good weather in Florence?
Planning for the weather is a good way to make your trip to Florence relaxing and enjoyable, especially when you’re splurging. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches.
What's there to see and do in Florence?
Take in the sights and attractions that Florence offers with a visit to Florence Museum, Florence National Cemetery, and Magnolia Mall. If you have extra time while you’re in the area, you might want to stop by Florence Civic Center and Palmetto Shores Lake.
How can I get around Florence?
It’s easier to get around town in style when you know your options. If you want to venture outside of the area, hop aboard a train at Florence Station.