Find Business Hotels in Florence, SC
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Florence Business Hotels
Top Florence Business Hotels
Our top choices for Florence business-friendly hotels

Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SC
9.0 out of 10, Wonderful, (2125)
The price is SAR 315
SAR 353 total
includes taxes & fees
1 Sep - 2 Sep

Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florence
8.8 out of 10, Excellent, (2345)
The price is SAR 267
SAR 299 total
includes taxes & fees
3 Sep - 4 Sep

Hyatt Place Florence Downtown
Hyatt Place Florence Downtown
8.8 out of 10, Excellent, (1007)
The price is SAR 402
SAR 450 total
includes taxes & fees
16 Sep - 17 Sep

Comfort Inn & Suites
Comfort Inn & Suites
9.2 out of 10, Wonderful, (1059)
The price is SAR 399
SAR 446 total
includes taxes & fees
14 Sep - 15 Sep

La Quinta Inn & Suites by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florence
8.0 out of 10, Very Good, (1681)
The price is SAR 364
SAR 407 total
includes taxes & fees
1 Sep - 2 Sep

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
8.6 out of 10, Excellent, (1004)
The price is SAR 417
SAR 467 total
includes taxes & fees
14 Sep - 15 Sep

Hampton Inn & Suites Florence-North-I-95
Hampton Inn & Suites Florence-North-I-95
9.0 out of 10, Wonderful, (736)
The price is SAR 459
SAR 514 total
includes taxes & fees
7 Sep - 8 Sep

TownePlace Suites by Marriott Florence
TownePlace Suites by Marriott Florence
9.0 out of 10, Wonderful, (635)
The price is SAR 402
SAR 451 total
includes taxes & fees
3 Sep - 4 Sep
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Florence Hotel Reviews
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Find More Hotels near Florence
More Hotel Options in Florence
- Adventure Hotels in Florence
- Beach Hotels in Florence
- Boutique Hotels in Florence
- Cheap Hotels in Florence
- Family Hotels in Florence
- Golf Hotels in Florence
- Historic Hotels in Florence
- Hotel Wedding Venues in Florence
- Hotel with a Concierge in Florence
- Hotels with Bars in Florence
- Hotels with Free Parking in Florence
- Hotels with Hot Tubs in Florence
- Hotels with WiFi in Florence
- Hotels with a Pool in Florence
- Hotels with an Indoor Pool in Florence
- Hotels with smoking rooms in Florence
- Luxury Hotels in Florence
- Pet-friendly Hotels in Florence
- Resorts & Hotels with Spas in Florence
- Romantic Hotels in Florence
- Shopping Hotels in Florence
More Accommodation Types in Florence
- Condo Rentals in South Carolina
- Vacation Homes in South Carolina
- Apartments in South Carolina
- Villas in South Carolina
- Resorts in South Carolina
- Cottages in South Carolina
- Cabin Rentals in South Carolina
- Aparthotels in South Carolina
- Motels in South Carolina
- Guest Houses in South Carolina
- B&B in South Carolina
- Lodges in South Carolina
- Houseboats in South Carolina
- Condo Resorts in South Carolina
- Inns in South Carolina
- Country Houses in South Carolina
- Hostels in South Carolina
Hotels near popular Florence Attractions
- Hotels near Florence Civic Center
- Hotels near Magnolia Mall
- Hotels near Mcleod Regional Medical Center
- Hotels near Francis Marion University
- Hotels near Eastern Carolina Agricultural Fairgrounds
- Hotels near Florence Museum
- Hotels near Florence National Cemetery
- Hotels near Florence Veterans Park
- Hotels near The Traces Golf Club
- Hotels near Oakdale Country Club
Florence Hotels by Star Rating
Explore more hotels
- Residence Inn Marriott Florence
- Home2 Suites by Hilton Florence, SC
- Tru by Hilton Florence I-95
- Aloft Florence
- Quality Inn & Suites Florence Civic Center
- Hampton Inn & Suites Florence Center
- Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
- Comfort Suites Florence I-95
- Sleep Inn Florence North
- Staybridge Suites Florence - Civic Center by IHG
- Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
- Hampton Inn & Suites Florence-North-I-95
- SpringHill Suites by Marriott Florence
- Super 8 by Wyndham Florence
- Hotel Florence, Tapestry Collection by Hilton
- Motel 6 Florence, SC
- Homewood Suites by Hilton Florence
- Spark by Hilton Florence North I-95, SC
- Best Western Inn
- Clarion Inn & Suites