A modern building with a curved glass facade, surrounded by a well-maintained lawn and several trees.

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18 Oct - 19 Oct
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19 Oct - 20 Oct
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23 Oct - 25 Oct
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Our top choices for Mcleod Regional Medical Center hotels

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.
A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.
A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.

1. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
0.7 km from Mcleod Regional Medical Center
United States
Ivette
SAR 375
SAR 420 total
includes taxes & fees
3 Nov - 4 Nov
Hyatt Place Florence Downtown
A restaurant with brick walls, framed awards, and a bar area.
A bar area with a curved counter, multiple stools, and a brick wall backdrop.
A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.
An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.

2. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
0.8 km from Mcleod Regional Medical Center
United States
Ankh
SAR 520
SAR 582 total
includes taxes & fees
25 Oct - 26 Oct
Hotel Florence, Tapestry Collection by Hilton
A sign for the Rodeway Inn.

3. Rodeway Inn Florence Downtown

Rodeway Inn Florence Downtown
1.2 km from Mcleod Regional Medical Center
United States
F
SAR 159
SAR 184 total
includes taxes & fees
17 Nov - 18 Nov
Rodeway Inn Florence Downtown
A modern kitchen with stainless steel appliances, a gray sofa, and a ceiling fan.
A modern kitchen with a built-in dishwasher, a large island with a sink, pendant lights, and a ceiling fan.
A modern living room with a brick wall, a grey sofa, a wooden coffee table, and a view through large windows.
A modern living room with a grey sofa, a round coffee table, a grey armchair with patterned cushions, a floor lamp, and a large TV mounted on the wall.

4. The Urban Flats

The Urban Flats
0.8 km from Mcleod Regional Medical Center
SAR 923
SAR 1,597 total
includes taxes & fees
27 Oct - 28 Oct
The Urban Flats
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.
A fire pit surrounded by chairs and tables, with a staircase leading to an entrance, and a large window with a curtain.
A hotel room with a bed, a desk, a TV, a refrigerator, and a painting on the wall.
A hotel room with a sofa, a dining table, a coffee maker, a TV, and artwork on the wall.

5. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
8.1 km from Mcleod Regional Medical Center
United States
Tishia
SAR 492
SAR 551 total
includes taxes & fees
15 Nov - 16 Nov
Staybridge Suites Florence - Civic Center by IHG
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.
A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

6. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
5.5 km from Mcleod Regional Medical Center
United States
Juan
SAR 335
SAR 375 total
includes taxes & fees
1 Nov - 2 Nov
Park Inn by Radisson Florence, SC
A hotel lobby with a reception desk, seating area, and a television screen.
A hotel room with a bed, a sofa, an ottoman, and a lamp.
A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.
A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

7. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
7 km from Mcleod Regional Medical Center
United States
Mila
SAR 380
SAR 425 total
includes taxes & fees
8 Nov - 9 Nov
Comfort Inn & Suites Florence Center Area
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.
An outdoor patio area with brick walls, a fire pit, and outdoor seating.
A hotel lobby with a reception desk, seating area, and artwork on the walls.

8. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
9.1 km from Mcleod Regional Medical Center
United States
Christopher
SAR 477
SAR 571 total
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.
A Hampton Inn & Suites hotel with a well-lit entrance, multiple floors, and a parking area.
An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.
A lobby with leather sofas, a coffee table, potted plants, and a reception desk.

9. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
5.7 km from Mcleod Regional Medical Center
United States
Ashokraju
SAR 459
SAR 514 total
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn & Suites Florence-North-I-95
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.
A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.
A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.

10. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
5.5 km from Mcleod Regional Medical Center
United States
Alanda
SAR 242
SAR 272 total
includes taxes & fees
20 Oct - 21 Oct
Howard Johnson by Wyndham Florence
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.
A modern hotel room with a kitchenette, a grey sofa, a dining area, and a sign that reads "A Great Day Starts With Breakfast."
A modern lounge area with a sofa, armchairs, and small tables.
A self-service beverage station with refrigerated and non-refrigerated drink options, snack shelves, and a sign indicating the location.

11. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
7 km from Mcleod Regional Medical Center
United States
Crystal
SAR 411
SAR 461 total
includes taxes & fees
1 Nov - 2 Nov
TownePlace Suites by Marriott Florence
A hotel entrance with a stone facade, glass doors, and a number '501' above.
A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.
A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.
An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.

12. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
6.9 km from Mcleod Regional Medical Center
United States
Alma
SAR 443
SAR 497 total
includes taxes & fees
25 Oct - 26 Oct
Fairfield Inn & Suites by Marriott Florence I-20
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.
A modern hotel with a prominent 'TRU by Hilton' sign, a well-lit entrance, and a landscaped front yard.
A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.
A snack kiosk with a variety of snacks and beverages, a sign for a 24/7 market, and a sign for local items.

13. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
5.9 km from Mcleod Regional Medical Center
United States
Margarita
SAR 411
SAR 483 total
includes taxes & fees
25 Oct - 26 Oct
Tru by Hilton Florence I-95
A building with two red doors, one labeled 'Office' and the other '101'. There is a welcome sign and a mailbox on the wall.
A house with a stone-paved entrance, a bench, and two red doors labeled "OFFICE" and "PRIVATE."
A compact kitchen with a dining area, a TV, and a small table.
A room with a sofa, a small table, a chair, a lamp, and a door.

14. Affordable Suites Florence

Affordable Suites Florence
7 km from Mcleod Regional Medical Center
United States
Cheyenne
SAR 289
SAR 323 total
includes taxes & fees
18 Nov - 19 Nov
Affordable Suites Florence
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.
A hotel with a modern design, featuring a prominent sign for the 'Country Inn & Suites by Radisson.'
A hotel room with two beds, a desk with a chair, a television, and a window with curtains.
A modern cafeteria with long wooden tables, green chairs, and yellow accents.

15. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
5.5 km from Mcleod Regional Medical Center
United States
Tienia
SAR 364
SAR 422 total
includes taxes & fees
25 Oct - 26 Oct
Spark by Hilton Florence North I-95, SC
A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.
A hotel with a modern design, featuring multiple floors and a parking lot.
A modern hotel lobby with a fireplace, seating area, and a reception desk.
A modern hotel lobby with a central seating area, a large abstract painting, and a patterned carpet.

16. Residence Inn Marriott Florence

Residence Inn Marriott Florence
7.2 km from Mcleod Regional Medical Center
United States
Teri
SAR 402
SAR 451 total
includes taxes & fees
8 Nov - 9 Nov
Residence Inn Marriott Florence
A spacious lobby with a reception desk, seating area, and large windows.
A spacious lobby with a large fireplace, comfortable seating, and potted plants.
An indoor swimming pool with clear poolside areas, a lifeguard station, and a view of the outside.
A Hilton Garden Inn with a large, multi-story building, a covered entrance, and a parking lot.

17. Hilton Garden Inn Florence

Hilton Garden Inn Florence
7.2 km from Mcleod Regional Medical Center
United States
Derrick
SAR 443
SAR 497 total
includes taxes & fees
25 Oct - 26 Oct
Hilton Garden Inn Florence
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.
A snack and beverage display area with shelves stocked with various brands and a refrigerator with beverages.
A coffee station with two coffee machines and a display of coffee pods and cups.
A modern indoor space with a counter, seating area, and a blue accent wall.

18. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
8 km from Mcleod Regional Medical Center
United States
Leigh
SAR 428
SAR 479 total
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A lobby with a fireplace, seating area, and a television.
A hotel room with two beds, a desk, a TV, and a window with patterned curtains.
A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.

19. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
7.2 km from Mcleod Regional Medical Center
United States
Ryan
SAR 427
SAR 479 total
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn & Suites Florence Center
A hotel room with a desk, chair, bed, and a yellow sofa.
A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.
A hotel dining area with wooden tables and chairs, a fireplace, and a television.
A swimming pool with lounge chairs and a building with balconies.

20. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
7.5 km from Mcleod Regional Medical Center
United States
Sharhonda
SAR 334
SAR 375 total
includes taxes & fees
25 Oct - 26 Oct
Quality Inn & Suites Florence Civic Center
View all properties

Top Mcleod Regional Medical Center Hotel Reviews

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

8/10 Good
"Great location, right off highway easy off/on, lots of restaurants and gas stations. Hotel clean, convenient, and staff was friendly."
Kathy 1-night trip
Posted 1 hour ago
Howard Johnson by Wyndham Florence
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

8/10 Good
"Our room was very nice but that's where the rest failed! If you are going to offer a free breakfast there needs to be more oversight. There were a few pancakes but no bacon. There was no syrup for the pancakes. There were no forks available. The 2 juices offered were both gone. The "hot" water for oatmeal was cold. Need I say more? We will rethink another stay at Spark."
David 2-night trip
Posted 3 hours ago
Spark by Hilton Florence North I-95, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

8/10 Good
"We had a bad experience with a Comfort Suites in PA but decided to give this one a chance. It is a decent hotel, clean, and staff friendly. The electric went out for a few hours and staff immediately had lanterns in stairwells. Kudo’s !"
Darlene 1-night trip
Posted 23 hours ago
Comfort Inn & Suites Florence Center Area
Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

10/10 Excellent
"Fancy bathroom/Closet door"
Paul 1-night trip
Posted 2 days ago
Hampton Inn & Suites Florence Center
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

8/10 Good
"The staff were great!! Parking was close by and easy. The restaurant bar was a great stop. If you want a refrigerator in your room you need to ask prior to arrival."
Wendy 1-night trip
Posted 8 days ago
Hotel Florence, Tapestry Collection by Hilton
Pineapple House: Historic. Southern Charm. Walk Downtown.

Pineapple House: Historic. Southern Charm. Walk Downtown.

10/10 Excellent
"Absolutely beautiful home in a quiet, safe neighborhood. It had everything I needed for an incredible stay. Excellent water pressure in shower. Comfortable bed, beautiful decor, snacks, water, and communication with owner was excellent. Easy check in and check out. Thank you for your hospitality and for being so welcoming during my stay. This is THE place to stay in Florence, SC. Thank you again. I will return in the future."
Leanna F. 3-night trip
Posted 1 month ago
Pineapple House: Historic. Southern Charm. Walk Downtown.
Come Stay A While

Come Stay A While

10/10 Excellent
"Loved the in unit washer and dryer. The house was visibly clean and smelled clean. Plenty of towels. The kitchen had cutting boards and pots and pans. Very comfortable and nice neighborhood. Host was very responsive."
Anndria C. 14-night trip
Posted 3 months ago
Come Stay A While

Frequently asked questions

What's the area like around Mcleod Regional Medical Center?
Mcleod Regional Medical Center is located in a welcoming area of Florence known for its array of dining options. If you're looking for a convenient place to stay, check out the 18 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay near Mcleod Regional Medical Center?
Hyatt Place Florence Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.4 mi (0.7 km) from Mcleod Regional Medical Center. Other good options within a short distance include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.
How many hotels will I find near Mcleod Regional Medical Center?
Expedia has 18 hotels and other accommodations within a mile from Mcleod Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Mcleod Regional Medical Center, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals near Mcleod Regional Medical Center.
Where can I learn more about changing or cancelling my trip in the area near Mcleod Regional Medical Center?
For more information about updating your stay near Mcleod Regional Medical Center or cancelling it, click here.
What can I see and do near Mcleod Regional Medical Center?
You can enjoy live performances at FMU Performing Arts Center and Florence Little Theatre. You might spend a leisurely day outdoors at Florence Veterans Park and Greenwood Baseball Park and Playground. Create some family memories at Sky Zone Trampoline Park and Tilt Studio.