A modern building with a curved glass facade, surrounded by a well-maintained lawn and several trees.

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Our top choices for Mcleod Regional Medical Center hotels

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A modern lounge area with brick walls, large windows, and contemporary furniture.
A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.
A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.

1. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
0.7 km from Mcleod Regional Medical Center
United States
Ivette
SAR 413
SAR 463 total
includes taxes & fees
8 Oct - 9 Oct
Hyatt Place Florence Downtown
A restaurant with brick walls, framed awards, and a bar area.
An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.
A bar area with a curved counter, multiple stools, and a brick wall backdrop.
A spacious kitchen with a dining area, a living room with a fireplace, and a cozy seating arrangement.

2. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
0.8 km from Mcleod Regional Medical Center
United States
Ankh
SAR 477
SAR 534 total
includes taxes & fees
19 Oct - 20 Oct
Hotel Florence, Tapestry Collection by Hilton
A sign for the Rodeway Inn.

3. Rodeway Inn Florence Downtown

Rodeway Inn Florence Downtown
1.2 km from Mcleod Regional Medical Center
United States
F
SAR 160
SAR 184 total
includes taxes & fees
29 Oct - 30 Oct
Rodeway Inn Florence Downtown
A modern kitchen with stainless steel appliances, a gray sofa, and a ceiling fan.
A modern kitchen with grey cabinets, stainless steel appliances, and bar stools.
A modern kitchen with a built-in dishwasher, a large island with a sink, pendant lights, and a ceiling fan.
A modern living room with a grey sofa, a round coffee table, a grey armchair with patterned cushions, a floor lamp, and a large TV mounted on the wall.

4. The Urban Flats

The Urban Flats
0.8 km from Mcleod Regional Medical Center
SAR 945
SAR 1,622 total
includes taxes & fees
27 Oct - 28 Oct
The Urban Flats
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.
A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

5. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
5.5 km from Mcleod Regional Medical Center
United States
Windia
SAR 335
SAR 376 total
includes taxes & fees
4 Oct - 5 Oct
Park Inn by Radisson Florence, SC
A hotel lobby with a reception desk, seating area, and a television screen.
A hotel room with a bed, a sofa, an ottoman, and a lamp.
A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.
A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

6. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
7 km from Mcleod Regional Medical Center
United States
Mila
SAR 380
SAR 425 total
includes taxes & fees
21 Oct - 22 Oct
Comfort Inn & Suites Florence Center Area
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.
A coffee station with two coffee machines and a display of coffee pods and cups.
A modern office space with a long table, two chairs, a desk with a computer, and a wall-mounted colorful artwork.
A Holiday Inn Express & Suites hotel with a covered entrance, palm trees, and a clear sky.

7. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
8 km from Mcleod Regional Medical Center
United States
Leigh
SAR 428
SAR 479 total
includes taxes & fees
18 Oct - 19 Oct
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.
A lobby with leather sofas, a coffee table, potted plants, and a reception desk.
An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.
A corridor with shelves stocked with snacks and a frozen food display.

8. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
5.7 km from Mcleod Regional Medical Center
United States
Ashokraju
SAR 443
SAR 497 total
includes taxes & fees
7 Oct - 8 Oct
Hampton Inn & Suites Florence-North-I-95
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.
A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.
A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.

9. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
5.5 km from Mcleod Regional Medical Center
United States
HOMERO
SAR 243
SAR 272 total
includes taxes & fees
7 Oct - 8 Oct
Howard Johnson by Wyndham Florence
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.
A conference room with round tables, chairs, and a carpeted floor.
An outdoor kitchen area with a grill, a pool, and a covered seating area.
A hotel room with a bed, a desk, a TV, a refrigerator, and a painting on the wall.

10. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
8.1 km from Mcleod Regional Medical Center
United States
Tishia
SAR 537
SAR 601 total
includes taxes & fees
18 Oct - 19 Oct
Staybridge Suites Florence - Civic Center by IHG
A hotel entrance with a stone facade, glass doors, and a number '501' above.
A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.
A corner market with shelves stocked with snacks and beverages, and two large refrigerators.
A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.

11. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
6.9 km from Mcleod Regional Medical Center
United States
Felecia
SAR 476
SAR 533 total
includes taxes & fees
3 Oct - 4 Oct
Fairfield Inn & Suites by Marriott Florence I-20
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.
A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.
A modern lounge area with a sofa, armchairs, and small tables.
A self-service beverage station with refrigerated and non-refrigerated drink options, snack shelves, and a sign indicating the location.

12. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
7 km from Mcleod Regional Medical Center
United States
Crystal
SAR 444
SAR 497 total
includes taxes & fees
12 Oct - 13 Oct
TownePlace Suites by Marriott Florence
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.
A snack kiosk with a variety of snacks and beverages, a sign for a 24/7 market, and a sign for local items.
A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.
A modern hotel with a prominent 'TRU by Hilton' sign, a well-lit entrance, and a landscaped front yard.

13. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
5.9 km from Mcleod Regional Medical Center
United States
Tiffany
SAR 366
SAR 433 total
includes taxes & fees
7 Oct - 8 Oct
Tru by Hilton Florence I-95
A building with two red doors, one labeled 'Office' and the other '101'. There is a welcome sign and a mailbox on the wall.
A compact kitchen with a dining area, a TV, and a small table.
A room with a sofa, a small table, a chair, a lamp, and a door.
A compact living space with a dining area, kitchenette, and seating area.

14. Affordable Suites Florence

Affordable Suites Florence
7 km from Mcleod Regional Medical Center
United States
Cheyenne
SAR 270
SAR 303 total
includes taxes & fees
19 Oct - 20 Oct
Affordable Suites Florence
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.
A modern cafeteria with long wooden tables, green chairs, and yellow accents.
A hotel room with two beds, a desk with a chair, a television, and a window with curtains.
A hotel with a modern design, featuring a prominent sign for the 'Country Inn & Suites by Radisson.'

15. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
5.5 km from Mcleod Regional Medical Center
United States
Tienia
SAR 305
SAR 356 total
includes taxes & fees
11 Oct - 12 Oct
Spark by Hilton Florence North I-95, SC
A spacious lobby with a reception desk, seating area, and large windows.
A Hilton Garden Inn with a large, multi-story building, a covered entrance, and a parking lot.
A spacious lobby with a large fireplace, comfortable seating, and potted plants.
A reception area with a counter, a sign for 'The Pavilion Pantry', and a green wall.

16. Hilton Garden Inn Florence

Hilton Garden Inn Florence
7.2 km from Mcleod Regional Medical Center
United States
Derrick
SAR 428
SAR 479 total
includes taxes & fees
18 Oct - 19 Oct
Hilton Garden Inn Florence
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.
A hotel reception area with a modern design, including a reception desk, seating area, and a dining section.
A hotel reception desk with two computer monitors, a desk lamp, and framed artwork on the wall.
A large, two-story building with a central entrance flanked by columns, labeled "DIR FRANK B. LEE NURSING BUILDING."

17. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
9.1 km from Mcleod Regional Medical Center
United States
Christopher
SAR 428
SAR 517 total
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.
A lobby with a fireplace, seating area, and a television.
A hotel lobby with a reception desk, seating area, and a welcome mat.

18. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
7.2 km from Mcleod Regional Medical Center
United States
Ryan
SAR 415
SAR 464 total
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn & Suites Florence Center
A hotel room with a desk, chair, bed, and a yellow sofa.
A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.
A hotel dining area with wooden tables and chairs, a fireplace, and a television.
A swimming pool with lounge chairs and a building with balconies.

19. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
7.5 km from Mcleod Regional Medical Center
Canada
Noémie
SAR 331
SAR 371 total
includes taxes & fees
18 Oct - 19 Oct
Quality Inn & Suites Florence Civic Center
A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.
A modern coffee station with a counter, coffee machines, and a seating area with chairs.
A hotel room with a bed, a blue sofa, a brown ottoman, a black office chair, a desk, a lamp, and three framed pictures on the wall.
A Comfort Suites hotel with a modern design, featuring a prominent entrance with columns, a covered walkway, and a clear blue sky.

20. Comfort Suites Florence I-95

Comfort Suites Florence I-95
5.9 km from Mcleod Regional Medical Center
United States
Denise
SAR 342
SAR 399 total
includes taxes & fees
25 Oct - 26 Oct
Comfort Suites Florence I-95
View all properties

Top Mcleod Regional Medical Center Hotel Reviews

Boutique Private Apt Walk to Downtown Florence

Boutique Private Apt Walk to Downtown Florence

10/10 Excellent
"Great stay!"
Aaron J. 23-night trip
Posted 13 hours ago
Boutique Private Apt Walk to Downtown Florence
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

8/10 Good
"For one night while traveling, this hote filled the bill."
Fred 1-night trip
Posted 1 day ago
La Quinta Inn & Suites by Wyndham Florence
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

10/10 Excellent
"Great customer service,great breakfast"
Revenel 1-night trip
Posted 1 day ago
Spark by Hilton Florence North I-95, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

10/10 Excellent
"This property was just off the highway and was super clean. We were not expecting much for a pet friendly hotel which was just off the highway. But it was a very pleasant stay… the staff at the front desk were so friendly and made a great first impression from booking in to belreakfast in the Am.. it was well stocked and kept very clean! Parking was well lit and room was very clean and had shampoo conditioner and body wash and lotion for use!"
Amy 1-night trip
Posted 2 days ago
Comfort Inn & Suites Florence Center Area
Best Western Inn

Best Western Inn

10/10 Excellent
"Clean rooms and friendly staff and great breakfast"
Steward Heikes 1-night trip
Posted 3 days ago
Best Western Inn
Pineapple House: Historic. Southern Charm. Walk Downtown.

Pineapple House: Historic. Southern Charm. Walk Downtown.

10/10 Excellent
"Absolutely beautiful home in a quiet, safe neighborhood. It had everything I needed for an incredible stay. Excellent water pressure in shower. Comfortable bed, beautiful decor, snacks, water, and communication with owner was excellent. Easy check in and check out. Thank you for your hospitality and for being so welcoming during my stay. This is THE place to stay in Florence, SC. Thank you again. I will return in the future."
Leanna F. 3-night trip
Posted 2 weeks ago
Pineapple House: Historic. Southern Charm. Walk Downtown.
Come Stay A While

Come Stay A While

10/10 Excellent
"Loved the in unit washer and dryer. The house was visibly clean and smelled clean. Plenty of towels. The kitchen had cutting boards and pots and pans. Very comfortable and nice neighborhood. Host was very responsive."
Anndria C. 14-night trip
Posted 3 months ago
Come Stay A While

Frequently asked questions

What's the area like around Mcleod Regional Medical Center?
Mcleod Regional Medical Center is located in a welcoming area of Florence known for its array of dining options. If you're looking for a convenient place to stay, check out the 18 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay near Mcleod Regional Medical Center?
Hyatt Place Florence Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.4 mi (0.7 km) from Mcleod Regional Medical Center. Other good options within a short distance include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.
How many hotels will I find near Mcleod Regional Medical Center?
Expedia has 18 hotels and other accommodations within a mile from Mcleod Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Mcleod Regional Medical Center, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals near Mcleod Regional Medical Center.
Where can I learn more about changing or cancelling my trip in the area near Mcleod Regional Medical Center?
For more information about updating your stay near Mcleod Regional Medical Center or cancelling it, click here.
What can I see and do near Mcleod Regional Medical Center?
You can enjoy live performances at FMU Performing Arts Center and Florence Little Theatre. You might spend a leisurely day outdoors at Florence Veterans Park and Greenwood Baseball Park and Playground. Create some family memories at Sky Zone Trampoline Park and Tilt Studio.