A modern building with a curved glass facade, surrounded by a well-maintained lawn and several trees.

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Our top choices for Mcleod Regional Medical Center hotels

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.
A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.
A modern lounge area with brick walls, large windows, and contemporary furniture.

1. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
0.7 km from Mcleod Regional Medical Center
United States
Ivette
SAR 375
SAR 421 total
includes taxes & fees
12 Oct - 13 Oct
Hyatt Place Florence Downtown
A restaurant with brick walls, framed awards, and a bar area.
A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.
A spacious kitchen with a dining area, a living room with a fireplace, and a cozy seating arrangement.
An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.

2. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
0.8 km from Mcleod Regional Medical Center
United States
Ankh
SAR 454
SAR 509 total
includes taxes & fees
1 Nov - 2 Nov
Hotel Florence, Tapestry Collection by Hilton
A sign for the Rodeway Inn.

3. Rodeway Inn Florence Downtown

Rodeway Inn Florence Downtown
1.2 km from Mcleod Regional Medical Center
United States
F
SAR 160
SAR 184 total
includes taxes & fees
1 Nov - 2 Nov
Rodeway Inn Florence Downtown
A modern kitchen with stainless steel appliances, a gray sofa, and a ceiling fan.
A modern kitchen with grey cabinets, stainless steel appliances, and bar stools.
A modern living room with a brick wall, a grey sofa, a wooden coffee table, and a view through large windows.
A modern living room with a grey sofa, a round coffee table, a grey armchair with patterned cushions, a floor lamp, and a large TV mounted on the wall.

4. The Urban Flats

The Urban Flats
0.8 km from Mcleod Regional Medical Center
SAR 945
SAR 1,621 total
includes taxes & fees
14 Oct - 15 Oct
The Urban Flats
A hotel lobby with a reception desk, seating area, and a television screen.
A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.
A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.
A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

5. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
7 km from Mcleod Regional Medical Center
United States
Mila
SAR 380
SAR 425 total
includes taxes & fees
25 Oct - 26 Oct
Comfort Inn & Suites Florence Center Area
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.
A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.
A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.

6. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
5.5 km from Mcleod Regional Medical Center
United States
Windia
SAR 335
SAR 376 total
includes taxes & fees
11 Oct - 12 Oct
Park Inn by Radisson Florence, SC
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.
A lobby with leather sofas, a coffee table, potted plants, and a reception desk.
An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.
A Hampton Inn & Suites hotel with a well-lit entrance, multiple floors, and a parking area.

7. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
5.7 km from Mcleod Regional Medical Center
United States
Ashokraju
SAR 460
SAR 515 total
includes taxes & fees
7 Oct - 8 Oct
Hampton Inn & Suites Florence-North-I-95
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.
A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.
A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.

8. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
5.5 km from Mcleod Regional Medical Center
United States
HOMERO
SAR 243
SAR 272 total
includes taxes & fees
4 Oct - 5 Oct
Howard Johnson by Wyndham Florence
A hotel entrance with a stone facade, glass doors, and a number '501' above.
A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.
An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.
A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.

9. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
6.9 km from Mcleod Regional Medical Center
United States
Felecia
SAR 444
SAR 497 total
includes taxes & fees
1 Nov - 2 Nov
Fairfield Inn & Suites by Marriott Florence I-20
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.
A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.
A snack kiosk with a variety of snacks and beverages, a sign for a 24/7 market, and a sign for local items.
A modern lounge area with seating, tables, and a pool table.

10. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
5.9 km from Mcleod Regional Medical Center
United States
Tiffany
SAR 380
SAR 448 total
includes taxes & fees
11 Oct - 12 Oct
Tru by Hilton Florence I-95
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.
A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.
A modern kitchen with a coffee station, a dining area with a table and chairs, and a living area with a sofa and a coffee table.
A modern lounge area with a sofa, armchairs, and small tables.

11. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
7 km from Mcleod Regional Medical Center
United States
Crystal
SAR 428
SAR 479 total
includes taxes & fees
2 Nov - 3 Nov
TownePlace Suites by Marriott Florence
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.
A hotel room with two beds, a desk with a chair, a television, and a window with curtains.
An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.
A modern cafeteria with long wooden tables, green chairs, and yellow accents.

12. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
5.5 km from Mcleod Regional Medical Center
United States
Tienia
SAR 316
SAR 369 total
includes taxes & fees
18 Oct - 19 Oct
Spark by Hilton Florence North I-95, SC
A spacious lobby with a reception desk, seating area, and large windows.
A Hilton Garden Inn with a large, multi-story building, a covered entrance, and a parking lot.
A reception area with a counter, a sign for 'The Pavilion Pantry', and a green wall.
An indoor swimming pool with clear poolside areas, a lifeguard station, and a view of the outside.

13. Hilton Garden Inn Florence

Hilton Garden Inn Florence
7.2 km from Mcleod Regional Medical Center
United States
Derrick
SAR 444
SAR 497 total
includes taxes & fees
11 Oct - 12 Oct
Hilton Garden Inn Florence
A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.
A modern hotel lobby with a fireplace, seating area, and a reception desk.
A spacious lobby with a large seating area, a flat-screen TV, and a fireplace.
A modern hotel lobby with a central seating area, a large abstract painting, and a patterned carpet.

14. Residence Inn Marriott Florence

Residence Inn Marriott Florence
7.2 km from Mcleod Regional Medical Center
United States
TERRENCE
SAR 417
SAR 468 total
includes taxes & fees
1 Nov - 2 Nov
Residence Inn Marriott Florence
A hotel room with a desk, chair, bed, and a yellow sofa.
A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.
A swimming pool with lounge chairs and a building with balconies.
A hotel dining area with wooden tables and chairs, a fireplace, and a television.

15. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
7.5 km from Mcleod Regional Medical Center
Canada
Noémie
SAR 331
SAR 371 total
includes taxes & fees
18 Oct - 19 Oct
Quality Inn & Suites Florence Civic Center
A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.
An outdoor patio area with tables and chairs, a barbecue grill, and a large window overlooking a fenced area.
A hotel room with a bed, a blue sofa, a brown ottoman, a black office chair, a desk, a lamp, and three framed pictures on the wall.
A Comfort Suites hotel with a modern design, featuring a prominent entrance with columns, a covered walkway, and a clear blue sky.

16. Comfort Suites Florence I-95

Comfort Suites Florence I-95
5.9 km from Mcleod Regional Medical Center
United States
Denise
SAR 338
SAR 394 total
includes taxes & fees
18 Oct - 19 Oct
Comfort Suites Florence I-95
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.
A lobby with a fireplace, seating area, and a television.
A hotel room with two beds, a desk, a TV, and a window with patterned curtains.

17. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
7.2 km from Mcleod Regional Medical Center
United States
Ryan
SAR 428
SAR 479 total
includes taxes & fees
11 Oct - 12 Oct
Hampton Inn & Suites Florence Center
Terrace/patio
An indoor swimming pool with lounge chairs and exercise equipment.
A hotel room with a desk, a green armchair, a small purple ottoman, a bed with a white headboard, and a large window.
A spacious lobby with a reception desk, seating area with patterned chairs, and a coffee station.

18. Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC
7.7 km from Mcleod Regional Medical Center
United States
saleh
SAR 412
SAR 483 total
includes taxes & fees
11 Oct - 12 Oct
Home2 Suites by Hilton Florence, SC
A modern hotel with a covered entrance, large windows, and a sign indicating it is a hotel.
A modern kitchen with a white countertop, three black stools, and a red accent wall.
A modern lounge area with a pool table, sofas, and yellow chairs.
A bar area with a neon sign, shelves of bottles, and a view of trees through large windows.

19. Aloft by Marriott Florence

Aloft by Marriott Florence
7.6 km from Mcleod Regional Medical Center
United States
SARAH
SAR 402
SAR 473 total
includes taxes & fees
7 Oct - 8 Oct
Aloft by Marriott Florence
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.
A hotel room with a bed, sofa, TV, and a desk.
A hotel room with a bed, a sofa, a desk, and a TV.
A La Quinta Inn & Suites hotel with a modern facade, a well-lit entrance, and a landscaped garden area.

20. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
5.7 km from Mcleod Regional Medical Center
United States
Heather
SAR 335
SAR 375 total
includes taxes & fees
5 Oct - 6 Oct
La Quinta Inn & Suites by Wyndham Florence
View all properties

Top Mcleod Regional Medical Center Hotel Reviews

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

8/10 Good
"The room was clean and it was a peaceful and quiet night of sleep. I appreciated the comfy bed and pillows. The air took awhile to actually cool the room off but it got cold after awhile (1+ hours). The breakfast was disappointing as the non-bread options were not replenished. I understand this at 9:55am. Not at 9.20am. The staff seemed annoyed to answer questions about the lack of breakfast food options or if they were being replenished."
Leah 1-night trip
Posted 6 hours ago
Park Inn by Radisson Florence, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

10/10 Excellent
"Every thing was good"
Vashtie 1-night trip
Posted 6 hours ago
Comfort Inn & Suites Florence Center Area
Best Western Inn

Best Western Inn

10/10 Excellent
"Clean rooms and friendly staff and great breakfast"
Steward Heikes 1-night trip
Posted 6 days ago
Best Western Inn
Pineapple House: Historic. Southern Charm. Walk Downtown.

Pineapple House: Historic. Southern Charm. Walk Downtown.

10/10 Excellent
"Absolutely beautiful home in a quiet, safe neighborhood. It had everything I needed for an incredible stay. Excellent water pressure in shower. Comfortable bed, beautiful decor, snacks, water, and communication with owner was excellent. Easy check in and check out. Thank you for your hospitality and for being so welcoming during my stay. This is THE place to stay in Florence, SC. Thank you again. I will return in the future."
Leanna F. 3-night trip
Posted 3 weeks ago
Pineapple House: Historic. Southern Charm. Walk Downtown.
Come Stay A While

Come Stay A While

10/10 Excellent
"Loved the in unit washer and dryer. The house was visibly clean and smelled clean. Plenty of towels. The kitchen had cutting boards and pots and pans. Very comfortable and nice neighborhood. Host was very responsive."
Anndria C. 14-night trip
Posted 3 months ago
Come Stay A While

Frequently asked questions

What's the area like around Mcleod Regional Medical Center?
Mcleod Regional Medical Center is located in a welcoming area of Florence known for its array of dining options. If you're looking for a convenient place to stay, check out the 18 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay near Mcleod Regional Medical Center?
Hyatt Place Florence Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.4 mi (0.7 km) from Mcleod Regional Medical Center. Other good options within a short distance include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.
How many hotels will I find near Mcleod Regional Medical Center?
Expedia has 18 hotels and other accommodations within a mile from Mcleod Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Mcleod Regional Medical Center, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals near Mcleod Regional Medical Center.
Where can I learn more about changing or cancelling my trip in the area near Mcleod Regional Medical Center?
For more information about updating your stay near Mcleod Regional Medical Center or cancelling it, click here.
What can I see and do near Mcleod Regional Medical Center?
You can enjoy live performances at FMU Performing Arts Center and Florence Little Theatre. You might spend a leisurely day outdoors at Florence Veterans Park and Greenwood Baseball Park and Playground. Create some family memories at Sky Zone Trampoline Park and Tilt Studio.