Find hotels near Mcleod Regional Medical Center, Florence from SAR 146

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4 Nov - 5 Nov
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Our top choices for Mcleod Regional Medical Center hotels

A restaurant with brick walls, framed awards, and a bar area.

1. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
0.8 km from Mcleod Regional Medical Center
8.8 out of 10, Excellent, (659 reviews)
"The house keeping people"
United States
WILLIE
The price is SAR 520
SAR 583 total
includes taxes & fees
5 Dec - 6 Dec
Hotel Florence, Tapestry Collection by Hilton
A sign for the Rodeway Inn.

2. Rodeway Inn Florence Downtown

Rodeway Inn Florence Downtown
2.0 star property
1.2 km from Mcleod Regional Medical Center
5.4 out of 10, (8 reviews)
"Air conditioning didn’t work on my last night, neither did the WiFi. Would not recommend"
United States
F
The price is SAR 146
SAR 169 total
includes taxes & fees
26 Nov - 27 Nov
Rodeway Inn Florence Downtown
A modern kitchen with stainless steel appliances, a gray sofa, and a ceiling fan.

3. The Urban Flats

The Urban Flats
4.0 star property
0.8 km from Mcleod Regional Medical Center
The price is SAR 799
SAR 1,458 total
includes taxes & fees
10 Nov - 11 Nov
The Urban Flats
A spacious lobby with a checkered floor, a reception desk, and a chandelier.

4. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
5.5 km from Mcleod Regional Medical Center
8.6 out of 10, Excellent, (2,749 reviews)
"Quiet clean and inexpensive stay, especially relative to neighboring locations"
United States
Carl
The price is SAR 228
SAR 256 total
includes taxes & fees
5 Nov - 6 Nov
Howard Johnson by Wyndham Florence
A hotel lobby with a reception desk, seating area, and a television screen.

5. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
7 km from Mcleod Regional Medical Center
9.0 out of 10, Wonderful, (1,388 reviews)
"Comfortable beds and clean environments."
United States
Steven
The price is SAR 380
SAR 425 total
includes taxes & fees
2 Dec - 3 Dec
Comfort Inn & Suites Florence Center Area
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

6. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
5.5 km from Mcleod Regional Medical Center
9.0 out of 10, Wonderful, (2,500 reviews)
"Great place to spend the night during our road trip. Would stay again."
United States
Susan
The price is SAR 339
SAR 379 total
includes taxes & fees
8 Nov - 9 Nov
Park Inn by Radisson Florence, SC
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

7. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
5.7 km from Mcleod Regional Medical Center
9.0 out of 10, Wonderful, (1,000 reviews)
"Excellente hotel, clean, good breakfast, and quiet."
Canada
chantal
The price is SAR 459
SAR 515 total
includes taxes & fees
2 Dec - 3 Dec
Hampton Inn & Suites Florence-North-I-95
A Holiday Inn Express & Suites hotel with a covered entrance, multiple windows, and a parking lot.

8. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
2.5 star property
9.1 km from Mcleod Regional Medical Center
8.6 out of 10, Excellent, (1,000 reviews)
"Good location- very good free breakfast"
United States
Christopher
The price is SAR 477
SAR 571 total
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

9. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
5.9 km from Mcleod Regional Medical Center
8.6 out of 10, Excellent, (1,001 reviews)
"Great hotel and staff"
United States
Margarita
The price is SAR 341
SAR 405 total
includes taxes & fees
15 Nov - 16 Nov
Tru by Hilton Florence I-95
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

10. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
5.5 km from Mcleod Regional Medical Center
8.4 out of 10, Very good, (349 reviews)
"Great staff easy Check in I love staying here!!!"
United States
Alanya
The price is SAR 364
SAR 430 total
includes taxes & fees
10 Nov - 11 Nov
Spark by Hilton Florence North I-95, SC
A hotel entrance with a stone facade, glass doors, and a number '501' above.

11. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
6.9 km from Mcleod Regional Medical Center
9.0 out of 10, Wonderful, (664 reviews)
"I enjoyed a two night stay here at Fairfield. The staff was completely awesome. The breakfast was amazing, so many options to choose from to meet every healthy meal plan. The amenities were very clean, modern and chic, providing an upscale experience. Overall experience was excellent!"
United States
Alma
The price is SAR 443
SAR 497 total
includes taxes & fees
2 Dec - 3 Dec
Fairfield Inn & Suites by Marriott Florence I-20
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

12. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
7 km from Mcleod Regional Medical Center
9.0 out of 10, Wonderful, (923 reviews)
"Fabulous pet-friendly place to stay."
United States
Ralph
The price is SAR 412
SAR 461 total
includes taxes & fees
2 Dec - 3 Dec
TownePlace Suites by Marriott Florence
A hotel room with a desk, a bed, a sofa, a TV, and a mirror.

13. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
7.5 km from Mcleod Regional Medical Center
8.4 out of 10, Very good, (420 reviews)
"Nice spot for an overnight!"
United States
Sharhonda
The price is SAR 334
SAR 375 total
includes taxes & fees
10 Nov - 11 Nov
Quality Inn & Suites Florence Civic Center
A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.

14. Residence Inn Marriott Florence

Residence Inn Marriott Florence
3.0 star property
7.2 km from Mcleod Regional Medical Center
8.8 out of 10, Excellent, (587 reviews)
"The room was clean and spacious. The staff was friendly."
United States
Teri
The price is SAR 402
SAR 451 total
includes taxes & fees
9 Nov - 10 Nov
Residence Inn Marriott Florence
A spacious lobby with a reception desk, seating area, and large windows.

15. Hilton Garden Inn Florence

Hilton Garden Inn Florence
2.5 star property
7.2 km from Mcleod Regional Medical Center
8.6 out of 10, Excellent, (361 reviews)
"Rooms were clean and staff was friendly."
United States
Derrick
The price is SAR 428
SAR 479 total
includes taxes & fees
22 Nov - 23 Nov
Hilton Garden Inn Florence
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.

16. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
5.7 km from Mcleod Regional Medical Center
7.8 out of 10, Good, (1,456 reviews)
"Close to the restaurants and shopping."
United States
Brenda
The price is SAR 334
SAR 375 total
includes taxes & fees
8 Nov - 9 Nov
La Quinta Inn & Suites by Wyndham Florence
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

17. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
7.2 km from Mcleod Regional Medical Center
9.0 out of 10, Wonderful, (1,004 reviews)
"Good location, clean room and good breakfast."
United States
NOORUDIN
The price is SAR 428
SAR 479 total
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn & Suites Florence Center
A hotel entrance with a covered walkway, columns, and a number '340' sign.

18. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
8 km from Mcleod Regional Medical Center
9.0 out of 10, Wonderful, (1,001 reviews)
"Wonderful hotel and in a great location!"
United States
Leigh
The price is SAR 428
SAR 479 total
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Terrace/patio

19. Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC
3.0 star property
7.7 km from Mcleod Regional Medical Center
8.4 out of 10, Very good, (1,001 reviews)
"Great for families"
United States
saleh
The price is SAR 428
SAR 501 total
includes taxes & fees
29 Nov - 30 Nov
Home2 Suites by Hilton Florence, SC
A hotel room with a checkered sofa, a bed, a desk, and a framed picture on the wall.

20. Best Western Inn

Best Western Inn
2.5 star property
4.7 km from Mcleod Regional Medical Center
7.8 out of 10, Good, (1,002 reviews)
"Clean rooms and friendly staff and great breakfast"
United States
Steward Heikes
The price is SAR 334
SAR 374 total
includes taxes & fees
5 Nov - 6 Nov
Best Western Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels near Mcleod Regional Medical Center

A restaurant with brick walls, framed awards, and a bar area.

Hotel Florence, Tapestry Collection by Hilton

3.0 star property
0.8 km from Mcleod Regional Medical Center
View
A sign for the Rodeway Inn.

Rodeway Inn Florence Downtown

2.0 star property
1.2 km from Mcleod Regional Medical Center
View
A spacious lobby with a checkered floor, a reception desk, and a chandelier.

Howard Johnson by Wyndham Florence

2.0 star property
5.5 km from Mcleod Regional Medical Center
View
A hotel lobby with a reception desk, seating area, and a television screen.

Comfort Inn & Suites Florence Center Area

2.5 star property
7 km from Mcleod Regional Medical Center
View
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

Park Inn by Radisson Florence, SC

2.5 star property
5.5 km from Mcleod Regional Medical Center
View
8.8
Excellent
659 reviews
5.4
8 reviews
8.6
Excellent
2,749 reviews
9.0
Wonderful
1,388 reviews
9.0
Wonderful
2,500 reviews
The price is SAR 520
SAR 583 total
includes taxes & fees
5 Dec - 6 Dec
The price is SAR 146
SAR 169 total
includes taxes & fees
26 Nov - 27 Nov
The price is SAR 228
SAR 256 total
includes taxes & fees
5 Nov - 6 Nov
The price is SAR 380
SAR 425 total
includes taxes & fees
2 Dec - 3 Dec
The price is SAR 339
SAR 379 total
includes taxes & fees
8 Nov - 9 Nov
  • No Breakfast included
  • No Pool
  • Yes, Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • No Pool
  • No Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • No Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • No Parking

Top Mcleod Regional Medical Center Hotel Reviews

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
Florence

10/10 Excellent

Room smelled pleasant like it was clean but not overpowered by chemicals. The facility was nice and clean. Only had one interaction with a staff member at check in and that was pleasant and quick. Would definitely return to this hotel and recommend it to others.
United States
Nichole
Reviewed March 25, 2026
Park Inn by Radisson Florence, SC

Frequently Asked Questions

What's the area like around Mcleod Regional Medical Center?

Mcleod Regional Medical Center is located in a welcoming area of Florence known for its array of dining options. If you're looking for a convenient place to stay, check out the 18 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay near Mcleod Regional Medical Center?

Hyatt Place Florence Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.4 mi (0.7 km) from Mcleod Regional Medical Center. Other good options within a short distance include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.

How many hotels will I find near Mcleod Regional Medical Center?

Expedia has 18 hotels and other accommodations within a mile from Mcleod Regional Medical Center.

If I need to cancel the hotel reservation for my stay near Mcleod Regional Medical Center, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable if you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals near Mcleod Regional Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Mcleod Regional Medical Center?

For more information about updating your stay near Mcleod Regional Medical Center or cancelling it, click here.

What can I see and do near Mcleod Regional Medical Center?

You can enjoy live performances at FMU Performing Arts Center and Florence Little Theatre. You might spend a leisurely day outdoors at Florence Veterans Park and Greenwood Baseball Park and Playground. Create some family memories at Sky Zone Trampoline Park and Tilt Studio.