The Best Hotels Closest to Mcleod Regional Medical Center in Florence for 2026

A modern building with a curved glass facade, surrounded by a well-maintained lawn and several trees.

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Our top choices for Mcleod Regional Medical Center hotels

A spa room with two armchairs, a small table with a vase of flowers, and a sign that reads "SPA Florence".

An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.

A restaurant with brick walls, framed awards, and a bar area.

A bar area with a curved counter, multiple stools, and a brick wall backdrop.

1. Hotel Florence, Tapestry Collection by Hilton

0.8 km from Mcleod Regional Medical Center

Ankh

SAR 520

SAR 583 total

includes taxes & fees

30 Oct - 31 Oct

2. Rodeway Inn Florence Downtown

1.2 km from Mcleod Regional Medical Center

SAR 160

SAR 184 total

includes taxes & fees

22 Nov - 23 Nov

A bedroom with a brick wall, a bed with white bedding, a wardrobe with dark doors, and a mirror.

A modern kitchen with stainless steel appliances, a gray sofa, and a ceiling fan.

A modern living room with a brick wall, a grey sofa, a wooden coffee table, and a view through large windows.

A modern living room with a grey sofa, a round coffee table, a grey armchair with patterned cushions, a floor lamp, and a large TV mounted on the wall.

3. The Urban Flats

0.8 km from Mcleod Regional Medical Center

SAR 923

SAR 1,597 total

includes taxes & fees

2 Nov - 3 Nov

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.

A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.

A two-story building with a brick facade, a flat roof, and a covered entrance area.

4. Howard Johnson by Wyndham Florence

5.5 km from Mcleod Regional Medical Center

Alanda

SAR 228

SAR 256 total

includes taxes & fees

25 Oct - 26 Oct

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.

A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.

5. Park Inn by Radisson Florence, SC

5.5 km from Mcleod Regional Medical Center

Amy

SAR 339

SAR 379 total

includes taxes & fees

8 Nov - 9 Nov

A hotel lobby with a reception desk, seating area, and a television screen.

A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

A hotel room with a bed, a sofa, an ottoman, and a lamp.

6. Comfort Inn & Suites Florence Center Area

7 km from Mcleod Regional Medical Center

Mila

SAR 380

SAR 425 total

includes taxes & fees

15 Nov - 16 Nov

A swimming pool with lounge chairs and a view of the outdoors.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.

A buffet with various food items, including omelets and baked goods, served in metal containers.

7. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

9.1 km from Mcleod Regional Medical Center

Christopher

SAR 458

SAR 550 total

includes taxes & fees

8 Nov - 9 Nov

A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

A Hampton Inn & Suites hotel with a well-lit entrance, multiple floors, and a parking area.

A lobby with leather sofas, a coffee table, potted plants, and a reception desk.

A corridor with shelves stocked with snacks and a frozen food display.

8. Hampton Inn & Suites Florence-North-I-95

5.7 km from Mcleod Regional Medical Center

Ladavish

SAR 459

SAR 515 total

includes taxes & fees

1 Nov - 2 Nov

A fire pit surrounded by chairs and tables, with a staircase leading to an entrance, and a large window with a curtain.

A hotel with a modern architectural design, featuring a prominent entrance canopy and a sign indicating it is a Staybridge Suites hotel.

A hotel lobby with a stone fireplace, recessed lighting, and a large plant.

A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

9. Staybridge Suites Florence - Civic Center by IHG

8.1 km from Mcleod Regional Medical Center

Tishia

SAR 492

SAR 551 total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.

A modern lounge area with a sofa, armchairs, and small tables.

A modern hotel room with a kitchenette, a grey sofa, a dining area, and a sign that reads "A Great Day Starts With Breakfast."

10. TownePlace Suites by Marriott Florence

7 km from Mcleod Regional Medical Center

Crystal

SAR 412

SAR 461 total

includes taxes & fees

1 Nov - 2 Nov

A hotel entrance with a stone facade, glass doors, and a number '501' above.

An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.

A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.

A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.

11. Fairfield Inn & Suites by Marriott Florence I-20

6.9 km from Mcleod Regional Medical Center

Alma

SAR 443

SAR 497 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a reception desk, seating area, and large windows.

A reception area with a counter, a sign for 'The Pavilion Pantry', and a green wall.

A Hilton Garden Inn with a large, multi-story building, a covered entrance, and a parking lot.

A spacious lobby with a large fireplace, comfortable seating, and potted plants.

12. Hilton Garden Inn Florence

7.2 km from Mcleod Regional Medical Center

Derrick

SAR 443

SAR 497 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a desk, chair, bed, and a yellow sofa.

A hotel dining area with wooden tables and chairs, a fireplace, and a television.

A swimming pool with lounge chairs and a building with balconies.

A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.

13. Quality Inn & Suites Florence Civic Center

7.5 km from Mcleod Regional Medical Center

Sharhonda

SAR 334

SAR 375 total

includes taxes & fees

2 Nov - 3 Nov

A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.

A spacious lobby with a large seating area, a flat-screen TV, and a fireplace.

A modern hotel lobby with a central seating area, a large abstract painting, and a patterned carpet.

A hotel with a modern design, featuring multiple floors and a parking lot.

14. Residence Inn Marriott Florence

7.2 km from Mcleod Regional Medical Center

Teri

SAR 402

SAR 451 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.

A hotel room with a bed, sofa, TV, and a desk.

A hotel room with a bed, a sofa, a desk, and a TV.

A La Quinta Inn & Suites hotel with a modern facade, a well-lit entrance, and a landscaped garden area.

15. La Quinta Inn & Suites by Wyndham Florence

5.7 km from Mcleod Regional Medical Center

Brenda

SAR 321

SAR 359 total

includes taxes & fees

25 Oct - 26 Oct

A multi-story hotel with a prominent entrance and signage for Springhill Suites by Marriott.

A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.

A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.

An indoor swimming pool with clear blue water, surrounded by green chairs and a tiled floor.

16. SpringHill Suites by Marriott Florence

7.2 km from Mcleod Regional Medical Center

John

SAR 381

SAR 449 total

includes taxes & fees

13 Nov - 14 Nov

A Holiday Inn Express & Suites hotel with a covered entrance, palm trees, and a clear sky.

A buffet with labeled trays of turkey sausage and cookies.

A snack and beverage display area with shelves stocked with various brands and a refrigerator with beverages.

A coffee station with two coffee machines and a display of coffee pods and cups.

17. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

8 km from Mcleod Regional Medical Center

Leigh

SAR 402

SAR 450 total

includes taxes & fees

22 Nov - 23 Nov

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.

A hotel lobby with a reception desk, seating area, and a welcome mat.

A lobby with a fireplace, seating area, and a television.

18. Hampton Inn & Suites Florence Center

7.2 km from Mcleod Regional Medical Center

William

SAR 351

SAR 393 total

includes taxes & fees

15 Nov - 16 Nov

An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.

A modern lounge area with seating, tables, and a pool table.

A snack kiosk with a variety of snacks and beverages, a sign for a 24/7 market, and a sign for local items.

19. Tru by Hilton Florence I-95

5.9 km from Mcleod Regional Medical Center

Margarita

SAR 341

SAR 405 total

includes taxes & fees

8 Nov - 9 Nov

A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.

A hotel with a modern design, featuring a prominent sign for the 'Country Inn & Suites by Radisson.'

A hotel room with two beds, a desk with a chair, a television, and a window with curtains.

20. Spark by Hilton Florence North I-95, SC

5.5 km from Mcleod Regional Medical Center

Tienia

SAR 284

SAR 340 total

includes taxes & fees

1 Nov - 2 Nov

View all properties

Compare top hotels near Mcleod Regional Medical Center

Hotel Florence, Tapestry Collection by Hilton 0.8 km from Mcleod Regional Medical Center View	Rodeway Inn Florence Downtown 1.2 km from Mcleod Regional Medical Center View	Howard Johnson by Wyndham Florence 5.5 km from Mcleod Regional Medical Center View	Park Inn by Radisson Florence, SC 5.5 km from Mcleod Regional Medical Center View	Comfort Inn & Suites Florence Center Area 7 km from Mcleod Regional Medical Center View
8.8 Excellent 658 reviews	5.4 8 reviews	8.6 Excellent 2,749 reviews	9.0 Wonderful 2,478 reviews	9.0 Wonderful 1,374 reviews
SAR 520 SAR 583 total includes taxes & fees 30 Oct - 31 Oct	SAR 160 SAR 184 total includes taxes & fees 22 Nov - 23 Nov	SAR 228 SAR 256 total includes taxes & fees 25 Oct - 26 Oct	SAR 339 SAR 379 total includes taxes & fees 8 Nov - 9 Nov	SAR 380 SAR 425 total includes taxes & fees 15 Nov - 16 Nov

Top Mcleod Regional Medical Center Hotel Reviews

Hyatt Place Florence Downtown

10/10 Excellent

"This spot is always on point.. I was even given the VIP Customer package…"

TownePlace Suites by Marriott Florence

8/10 Good

"Hannah at the desk was very sweet. I was disappointed that there was no body lotion provided. Also, the were 2 tissues in the box. Otherwise, bed was very cozy."

La Quinta Inn & Suites by Wyndham Florence

10/10 Excellent

"Close to the restaurants and shopping."

Days Inn by Wyndham Florence Near Civic Center

8/10 Good

"Room was great, but the complimentary breakfast was very poor."

Hotel Florence, Tapestry Collection by Hilton

8/10 Good

"The staff were great!! Parking was close by and easy. The restaurant bar was a great stop. If you want a refrigerator in your room you need to ask prior to arrival."

Come Stay A While

10/10 Excellent

"Loved the in unit washer and dryer. The house was visibly clean and smelled clean. Plenty of towels. The kitchen had cutting boards and pots and pans. Very comfortable and nice neighborhood. Host was very responsive."

Frequently asked questions

What's the area like around Mcleod Regional Medical Center?

Mcleod Regional Medical Center is located in a welcoming area of Florence known for its array of dining options. If you're looking for a convenient place to stay, check out the 18 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay near Mcleod Regional Medical Center?

Hyatt Place Florence Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.4 mi (0.7 km) from Mcleod Regional Medical Center. Other good options within a short distance include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.

How many hotels will I find near Mcleod Regional Medical Center?

Expedia has 18 hotels and other accommodations within a mile from Mcleod Regional Medical Center.

If I need to cancel the hotel reservation for my stay near Mcleod Regional Medical Center, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals near Mcleod Regional Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Mcleod Regional Medical Center?

For more information about updating your stay near Mcleod Regional Medical Center or cancelling it, click here.

What can I see and do near Mcleod Regional Medical Center?

You can enjoy live performances at FMU Performing Arts Center and Florence Little Theatre. You might spend a leisurely day outdoors at Florence Veterans Park and Greenwood Baseball Park and Playground. Create some family memories at Sky Zone Trampoline Park and Tilt Studio.

Find hotels near Mcleod Regional Medical Center, Florence from SAR 184

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Our top choices for Mcleod Regional Medical Center hotels

1. Hotel Florence, Tapestry Collection by Hilton

2. Rodeway Inn Florence Downtown

3. The Urban Flats

4. Howard Johnson by Wyndham Florence

5. Park Inn by Radisson Florence, SC

6. Comfort Inn & Suites Florence Center Area

7. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

8. Hampton Inn & Suites Florence-North-I-95

9. Staybridge Suites Florence - Civic Center by IHG

10. TownePlace Suites by Marriott Florence

11. Fairfield Inn & Suites by Marriott Florence I-20

12. Hilton Garden Inn Florence

13. Quality Inn & Suites Florence Civic Center

14. Residence Inn Marriott Florence

15. La Quinta Inn & Suites by Wyndham Florence

16. SpringHill Suites by Marriott Florence

17. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

18. Hampton Inn & Suites Florence Center

19. Tru by Hilton Florence I-95

20. Spark by Hilton Florence North I-95, SC

Compare top hotels near Mcleod Regional Medical Center

Hotel Florence, Tapestry Collection by Hilton

Rodeway Inn Florence Downtown

Howard Johnson by Wyndham Florence

Park Inn by Radisson Florence, SC

Comfort Inn & Suites Florence Center Area

Top Mcleod Regional Medical Center Hotel Reviews

Hyatt Place Florence Downtown

TownePlace Suites by Marriott Florence

La Quinta Inn & Suites by Wyndham Florence

Days Inn by Wyndham Florence Near Civic Center

Hotel Florence, Tapestry Collection by Hilton

Come Stay A While

Frequently asked questions