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Find All Southwest Illinois Hotels
We have found 673 Southwest Illinois Hotels
- Drury Inn & Suites St. Louis Arnold
- Holiday Inn Express and Suites Alton St Louis Area by IHG
- Pear Tree Inn Cape Girardeau West
- TownePlace Suites by Marriott Brentwood
- Days Inn and Suites by Wyndham Sikeston
- Hampton Inn & Suites St. Louis/Alton
- Sheraton Westport Plaza Hotel St. Louis
- Courtyard by Marriott St. Louis West County
- MainStay Suites St. Louis - Galleria
- Extended Stay America Select Suites St Louis Earth City
- Economy Inn & Suites
- Harrah's Metropolis Hotel & Casino
- Quality Inn & Suites Metropolis I-24
- Courtyard by Marriott Cape Girardeau Downtown
- Drury Inn & Suites Sikeston, MO
- The Lodge at Grant's Trail
- Staybridge Suites St Louis - Westport by IHG
- Holiday Inn Express Metropolis by IHG
- Comfort Inn Festus - St Louis South
- Holiday Inn Express & Suites Perryville by IHG
- Best Western Plus Parkway Hotel
- SpringHill Suites by Marriott St. Louis Airport/Earth City
- Quality Inn
- Americas Best Value Inn St. Louis Downtown
- Comfort Suites St. Louis - Sunset Hills
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
- Drury Inn & Suites Jackson MO
- Sheraton Westport Chalet Hotel St. Louis
- Microtel Inn & Suites by Wyndham Sainte Genevieve
- Residence Inn by Marriott St. Louis West County
- Hampton Inn St. Louis/Westport
- Fairfield Inn & Suites St Louis Westport
- Seven Gables, St. Louis West, a Tribute Portfolio Hotel
- Super 8 by Wyndham Metropolis
- Cobblestone Inn & Suites - Altamont
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Drury Inn & Suites Cape Girardeau
- Super 8 by Wyndham Perryville
- Grand Center Inn
- Welcome Suites Hazelwood
- Hampton Inn Cape Girardeau I 55 East
- Residence Inn by Marriott St Louis Airport
- Fairfield Inn & Suites by Marriott St. Louis South
- The Last Hotel
- Comfort Inn Alton near I-255
- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- Super 8 by Wyndham Harrisburg
- Hampton Inn by Hilton Litchfield
- Comfort Suites Jackson-Cape Girardeau
- Hotel 7 Vienna
- Tru By Hilton Cape Girardeau
- Motel 6 Metropolis, IL
- Days Inn by Wyndham Perryville
- Extended Stay America Select Suites St Louis Westport Craig
- Quality Inn Litchfield Route 66
- Hampton Inn St. Louis Southwest
- Super 8 by Wyndham Jerseyville
- Festus Inn
- MainStay Suites St Louis Airport
- Holiday Inn Express & Suites Litchfield West by IHG
- Homewood Suites by Hilton St. Louis Westport
- Super 8 by Wyndham Staunton
- Super 8 by Wyndham Alton
- Silo Farm Haus- located in the heart of wine country!
- Super 8 by Wyndham Sikeston/Miner Area
- Town House Inn Cape Giradreau
- WoodSpring Suites St. Louis Arnold
- Motel 6 Litchfield, IL
- Country Yard Inn and Suite
- Super 8 by Wyndham Charleston/Sikeston East MO
- Extended Stay America Suites - St Louis - Fenton
- Carlin Villa Motel
- Benton Park Inn
- OYO Hotel St. Louis Downtown City Center MO
- Quality Inn Perryville I-55
- Comfort Inn & Suites Sikeston I-55
- Quality Inn Charleston - Sikeston
- BEST WAY INN
- NEW property! Lakeside covered hot tub, A-frame 3 King Beds, Shawnee Forest
- Residence Inn St Louis Westport
- Quality Inn
- Cozy, Fun, and One-Of-A-Kind!
- Central West End B&B
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- CentralWestEnd-WashU-STL- Euphoria
- Quality Inn Florissant - St Louis
- Baymont by Wyndham Metropolis
- Indoor Heated Pool pontoon boat fish 3 full baths sleeps 17 in beds 2025 SALE!!!
- Super 8 by Wyndham Pevely
- Rockwood Inn
- Charming, Historic Family Suite, Steps from the Chase Park Plaza and Forest Park
- Charming Home with Country Views
- Historic Red Rooster Inn
- The Green Tree Inn
- St. Louis Airport Hotel