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Find Resorts & Hotels with Spas in Granite City, IL

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Top Granite City Resorts & Hotels with Spas

Ameristar Casino Resort and Spa

4.5 star property
St. Charles
8.4 out of 10, Very Good, (1000)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is SAR 571
SAR 730 total
includes taxes & fees
7 Dec - 8 Dec
Ameristar Casino Resort and Spa

21C Museum Hotel St Louis

4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1482)
"Staff is wonderful. We checked in late after a long journey and they could not have been nicer to us at check in also in the restaurant and bar. We loved the vibe and the location. I’d return again if ever in the area. "
United States
Jenifer
The price is SAR 475
SAR 575 total
includes taxes & fees
28 Dec - 29 Dec
21C Museum Hotel St Louis

Four Seasons Hotel St Louis

5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1002)
"The staff was amazing. The bed was so comfortable. "
United States
Mary
The price is SAR 1,558
SAR 1,821 total
includes taxes & fees
6 Jan - 7 January 2026
Four Seasons Hotel St Louis

The Ritz-Carlton, St. Louis

5.0 star property
Clayton
9.2 out of 10, Wonderful, (553)
"Service is exceptional!!!"
United States
Jorge
The price is SAR 1,873
SAR 2,186 total
includes taxes & fees
21 Dec - 22 Dec
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

Looking for a spa hotel in Granite City?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the historical sites and shopping in Granite City—your day trip starts here. Enjoy the lakeside setting during your vacation. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your vacation.
What's there to see and do in Granite City?
Experience Granite City and visit Cahokia Mounds State Historic Site, Mississippi River, and Missouri River. If you have extra time while you're in the area, you might want to stop by Horseshoe Lake State Park and Six Mile Regional Library District - Johnson Road.
What is a Granite City spa hotel?
Spa hotels in Granite City provide lodging and have an on-site spa offering services like therapies and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.