A large white building with a dome and a statue in front, surrounded by fountains and trees.

Find Resorts & Hotels with Spas in St. Louis, MO

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Check availability on St. Louis Resorts & Hotels with Spas

Tonight
25 Oct - 26 Oct
Tomorrow
26 Oct - 27 Oct
Next weekend
30 Oct - 1 Nov
In two weeks
6 Nov - 8 Nov

Our top choices for St. Louis hotels with a spa

A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
Spa
A modern lobby with a large glass sphere, seating areas, and a reception desk.

1. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
SAR 539
SAR 649 total
includes taxes & fees
15 Nov - 16 Nov
21C Museum Hotel St Louis
A well-lit lobby with a chandelier, potted plants, and a seating area.
A room with a dark wooden door, a chandelier, green plants, and a seating area with a sofa and chairs.
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.
A modern interior with a chandelier, a sofa, a coffee table, and a large painting on the wall.

2. Truitt Hotel

Truitt Hotel
Lafayette Square
SAR 631
SAR 765 total
includes taxes & fees
26 Oct - 27 Oct
Truitt Hotel
A couple relaxing by a window overlooking a bridge and water.
A modern hotel lobby with a glass facade, seating area, and a staircase.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.

3. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
SAR 1,408
SAR 1,646 total
includes taxes & fees
26 Oct - 27 Oct
Four Seasons Hotel St Louis
A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
A bakery display case with various pastries and cakes.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

4. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
SAR 508
SAR 656 total
includes taxes & fees
25 Nov - 26 Nov
Ameristar Casino Resort and Spa
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
A couple standing on a balcony with a cityscape view.
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
A bar area with leather seating, a bar counter, and shelves of bottles.

5. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
SAR 2,173
SAR 2,537 total
includes taxes & fees
1 Nov - 2 Nov
The Ritz-Carlton, St. Louis
View all properties

Choose what matters most at spa hotels in St. Louis

Pool
Hot tub
Breakfast included
Gym
5 stars

Top St. Louis Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"Love the evening manager’s reception and the breakfast. Drury always exceeds expectations! Great location close to the Arch. Great stay!"
Steven 1-night trip
Posted less than an hour ago
Drury Plaza Hotel St. Louis at the Arch
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent
"Excellent location and nice place!"
Briana 2-night trip
Posted 18 hours ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"Loved the location, amenities and large room with comfortable bed. We were able to walk to Enterprise Center. Particularly enjoyed the happy hour and breakfast. Did not appreciate the noise from the garbage collectors handling the huge dumpsters around 4am. For an upscale quality hotel you should contract to have quiet hours like midnight to 8am with any businesses your guest rooms face."
Debbie 1-night trip
Posted 2 days ago
Drury Plaza Hotel St. Louis Union Station
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"Great place"
Samuel 1-night trip
Posted 2 days ago
Ameristar Casino Resort and Spa

Frequently asked questions

Looking to vacation at a spa hotel in St. Louis?
Soothe the senses with some time in one of our wonderful spa hotels. Travelers love the fascinating museums and live music scene in St. Louis so get ready for a cultural tour. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in St. Louis?
Ameristar Casino Resort and Spa is a top luxury spa hotel featuring 6 restaurants, a casino, a 24-hour fitness center, and an outdoor pool. Treat yourself to a facial, body scrub, or hydrotherapy at Ara. Another popular spa hotel in St. Louis is Four Seasons Hotel St Louis.
How many spa hotels will I find in St. Louis?
Among Expedia's 1964 accommodation options in St. Louis, there are 2 spa hotels.
What's there to see and do in St. Louis?
Experience St. Louis and visit St. Louis Union Station, St. Louis Zoo, and St. Louis Aquarium at Union Station. If you have spare time during your trip, you might want to make a stop at The St. Louis Wheel and Energizer Park.
What is a St. Louis spa hotel?
Spa hotels in St. Louis provide lodging and have an on-site spa offering services like couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.