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Tonight
23 Aug - 24 Aug
Tomorrow
24 Aug - 25 Aug
Next weekend
28 Aug - 30 Aug
In two weeks
4 Sep - 6 Sep

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Our top choices for Mayo Clinic hotels

1. TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
Kutzky Park, 0.4 km from Mayo Clinic
United States
Jorge
SAR 477
SAR 549 total
includes taxes & fees
28 Aug - 29 Aug
TownePlace Suites by Marriott Rochester Mayo Clinic Area

2. Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Jennifer
SAR 644
SAR 741 total
includes taxes & fees
4 Sep - 5 Sep
Hilton Rochester Mayo Clinic Area

3. Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
2.6 km from Mayo Clinic
United States
Vickie
SAR 459
SAR 528 total
includes taxes & fees
30 Aug - 31 Aug
Home2 Suites by Hilton Rochester Mayo Clinic Area

4. Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
2.4 km from Mayo Clinic
United States
Richard
SAR 514
SAR 592 total
includes taxes & fees
4 Sep - 5 Sep
Residence Inn by Marriott Rochester Mayo Clinic Area South

5. The Berkman

The Berkman
Folwell, 1.4 km from Mayo Clinic
United States
William
SAR 769
SAR 894 total
includes taxes & fees
1 Sep - 2 Sep
The Berkman

6. EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Kutzky Park, 1 km from Mayo Clinic
United States
paul
SAR 379
SAR 487 total
includes taxes & fees
28 Aug - 29 Aug
EVEN Hotel Rochester - Mayo Clinic Area by IHG

7. The Towers At Kahler Grand Hotel

The Towers At Kahler Grand Hotel
Downtown Rochester, 0.1 km from Mayo Clinic
United States
Chris
SAR 1,348
SAR 1,552 total
includes taxes & fees
6 Sep - 7 Sep
The Towers At Kahler Grand Hotel

8. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
Kutzky Park, 1 km from Mayo Clinic
United States
Marissa
SAR 387
SAR 453 total
includes taxes & fees
4 Sep - 5 Sep
Staybridge Suites Rochester - Mayo Clinic Area by IHG

9. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Kutzky Park, 1.4 km from Mayo Clinic
United States
Lin
SAR 366
SAR 422 total
includes taxes & fees
4 Sep - 5 Sep
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

10. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Kutzky Park, 1.4 km from Mayo Clinic
United States
MATTHEW
SAR 389
SAR 448 total
includes taxes & fees
11 Sep - 12 Sep
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

11. Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG
2.6 km from Mayo Clinic
United States
Sean
SAR 436
SAR 501 total
includes taxes & fees
28 Aug - 29 Aug
Candlewood Suites Rochester Mayo Clinic Area by IHG

12. Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Camille
SAR 635
SAR 731 total
includes taxes & fees
4 Sep - 5 Sep
Broadway Plaza, Trademark Collection by Wyndham

13. Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
Downtown Rochester, 0.5 km from Mayo Clinic
United States
Bridgett
SAR 541
SAR 622 total
includes taxes & fees
18 Sep - 19 Sep
Hyatt House Rochester/Mayo Clinic Area

14. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
3.1 km from Mayo Clinic
United States
Markus
SAR 261
SAR 301 total
includes taxes & fees
13 Sep - 14 Sep
Econo Lodge Mayo Clinic Area

15. Aspen Suites

Aspen Suites
1.2 km from Mayo Clinic
United States
Jacey
SAR 504
SAR 609 total
includes taxes & fees
5 Sep - 6 Sep
Aspen Suites

16. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Downtown Rochester, 0.4 km from Mayo Clinic
United States
Kyle
SAR 349
SAR 402 total
includes taxes & fees
12 Sep - 13 Sep
Hotel Indigo Rochester – Mayo Clinic Area by IHG

17. Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Eileen
SAR 428
SAR 493 total
includes taxes & fees
4 Sep - 5 Sep
Hilton Garden Inn Rochester Downtown, MN

18. Brentwood Inn & Suites

Brentwood Inn & Suites
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Bryan
SAR 469
SAR 540 total
includes taxes & fees
24 Aug - 25 Aug
Brentwood Inn & Suites

19. Quality Inn & Suites Mayo Clinic Area

Quality Inn & Suites Mayo Clinic Area
2.6 km from Mayo Clinic
United States
Cassandra
SAR 286
SAR 333 total
includes taxes & fees
30 Aug - 31 Aug
Quality Inn & Suites Mayo Clinic Area

20. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Historic Southwest, 0.6 km from Mayo Clinic
United States
Brandolyn
SAR 429
SAR 494 total
includes taxes & fees
28 Aug - 29 Aug
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
View all properties

Compare popular hotels close to Mayo Clinic

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Pub
TownePlace Suites by Marriott Rochester Mayo Clinic Area
9.6
Exceptional
553 reviews
View
Presidential Suite, Multiple Beds | Living area | 55-inch LCD TV with satellite channels, TV
Hilton Rochester Mayo Clinic Area
9.6
Exceptional
641 reviews
View
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area
9.6
Exceptional
1,005 reviews
View
Indoor pool
Residence Inn by Marriott Rochester Mayo Clinic Area South
9.6
Exceptional
300 reviews
View
Lobby
The Berkman
9.6
Exceptional
427 reviews
View

Top Mayo Clinic Hotel Reviews

Kahler Grand Hotel

Kahler Grand Hotel

8/10 Good
"Check-in was a bit of a wait at 7:00 pm. Rooms are clean and updated. Our room had a very small bathroom with no counter space which we made work. The bed was quite firm which was fine for us. Pool and hot tub was great!"
Sandra 3-night trip
Posted 3 hours ago
Kahler Grand Hotel
Brentwood Inn & Suites

Brentwood Inn & Suites

10/10 Excellent
"The hotel is not super modern and it does not have super swank amenities, but the room was spotless, the staff were lovely, the breakfast was ample and easy for grab ‘n’ go, and the air conditioner in my room kept me nice and ICY cold during a horrendous heatwave. The property is in easy walking distance of the Domatilla Building (if you are a walker). I would definitely recommend this hotel. It’s very charming."
Kira 7-night trip
Posted 7 hours ago
Brentwood Inn & Suites
TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

10/10 Excellent
"Great staff"
Jonas 2-night trip
Posted 12 hours ago
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

8/10 Good
"the pool deck was very slippery."
Jerry 3-night trip
Posted 14 hours ago
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

10/10 Excellent
"Yoga matt, resistant bands are in the room. Providing a nice way to stretch. The room was large with alot of space to move"
Amelia 1-night trip
Posted 21 hours ago
EVEN Hotel Rochester - Mayo Clinic Area by IHG
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

8/10 Good
"Great location. Good value. Breakfast was laid out funny but ended up better than expected one morning a staff person was carrying on a very loud and angry phone call which went on for the length of the time we were there. Room was very good. Parking was not a problem."
Joe 4-night trip
Posted 1 day ago
AmericInn by Wyndham Rochester Near Mayo Clinic
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

8/10 Good
"Stayed for Mayo visit. Front desk staff and shuttle driver were fantastic. Room was very dated and in need of update, especially mattresses. Breakfast was better than expected. Overall had decent stay."
Kirk 4-night trip
Posted 1 day ago
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham

10/10 Excellent
"The space was perfect. Close to everywhere I needed. I love the pool and the workout room."
Diane 5-night trip
Posted 3 weeks ago
Broadway Plaza, Trademark Collection by Wyndham

Frequently asked questions

What's the area like around Mayo Clinic?
Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, check out the 150 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic?
Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Med City Inn & Suites - Mayo Clinic Area.
How many hotels will I be able to find near Mayo Clinic?
Expedia has 150 hotels and other accommodations within a mile from Mayo Clinic.
If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near Mayo Clinic.
Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic?
For additional details about rescheduling or cancelling your stay near Mayo Clinic, head over to our customer service page.
What can I see and do near Mayo Clinic?
You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Plummer House and Assisi Heights. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.