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Check prices for these dates

Tonight
8 Sep - 9 Sep
Tomorrow
9 Sep - 10 Sep
This weekend
11 Sep - 13 Sep
Next weekend
18 Sep - 20 Sep

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Our top choices for Mayo Clinic hotels

1. The Berkman

The Berkman
Folwell, 1.4 km from Mayo Clinic
United States
Jana
SAR 555
SAR 645 total
includes taxes & fees
10 Sep - 11 Sep
The Berkman

2. Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
2.6 km from Mayo Clinic
United States
Vickie
SAR 459
SAR 528 total
includes taxes & fees
18 Sep - 19 Sep
Home2 Suites by Hilton Rochester Mayo Clinic Area

3. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Kutzky Park, 1.8 km from Mayo Clinic
United States
Jon
SAR 419
SAR 482 total
includes taxes & fees
19 Sep - 20 Sep
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

4. TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
Kutzky Park, 0.4 km from Mayo Clinic
United States
Amanda
SAR 514
SAR 592 total
includes taxes & fees
19 Sep - 20 Sep
TownePlace Suites by Marriott Rochester Mayo Clinic Area

5. Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Jennifer
SAR 674
SAR 776 total
includes taxes & fees
19 Sep - 20 Sep
Hilton Rochester Mayo Clinic Area

6. EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Kutzky Park, 1 km from Mayo Clinic
United States
Ashley
SAR 394
SAR 505 total
includes taxes & fees
25 Sep - 26 Sep
EVEN Hotel Rochester - Mayo Clinic Area by IHG

7. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
Kutzky Park, 1 km from Mayo Clinic
United States
matthew
SAR 417
SAR 487 total
includes taxes & fees
12 Sep - 13 Sep
Staybridge Suites Rochester - Mayo Clinic Area by IHG

8. Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG
2.6 km from Mayo Clinic
United States
Sean
SAR 436
SAR 501 total
includes taxes & fees
13 Sep - 14 Sep
Candlewood Suites Rochester Mayo Clinic Area by IHG

9. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Kutzky Park, 1.4 km from Mayo Clinic
United States
MATTHEW
SAR 389
SAR 448 total
includes taxes & fees
18 Sep - 19 Sep
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

10. Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Camille
SAR 667
SAR 768 total
includes taxes & fees
19 Sep - 20 Sep
Broadway Plaza, Trademark Collection by Wyndham

11. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Kutzky Park, 1.4 km from Mayo Clinic
United States
Lin
SAR 428
SAR 493 total
includes taxes & fees
19 Sep - 20 Sep
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

12. Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
Downtown Rochester, 0.5 km from Mayo Clinic
United States
Mary Jo
SAR 443
SAR 510 total
includes taxes & fees
2 Oct - 3 Oct
Hyatt House Rochester/Mayo Clinic Area

13. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
3.1 km from Mayo Clinic
United States
James
SAR 263
SAR 303 total
includes taxes & fees
4 Oct - 5 Oct
Econo Lodge Mayo Clinic Area

14. Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.9 km from Mayo Clinic
United States
Lynne
SAR 354
SAR 408 total
includes taxes & fees
1 Oct - 2 Oct
Hampton Inn Rochester-South

15. Aspen Suites

Aspen Suites
1.2 km from Mayo Clinic
United States
Dr. suzette
SAR 533
SAR 644 total
includes taxes & fees
17 Sep - 18 Sep
Aspen Suites

16. Brentwood Inn & Suites

Brentwood Inn & Suites
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Richard
SAR 352
SAR 405 total
includes taxes & fees
10 Sep - 11 Sep
Brentwood Inn & Suites

17. Quality Inn & Suites Mayo Clinic Area

Quality Inn & Suites Mayo Clinic Area
2.6 km from Mayo Clinic
United States
Edward
SAR 287
SAR 335 total
includes taxes & fees
4 Oct - 5 Oct
Quality Inn & Suites Mayo Clinic Area

18. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Historic Southwest, 0.6 km from Mayo Clinic
United States
Carrie
SAR 405
SAR 466 total
includes taxes & fees
19 Sep - 20 Sep
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

19. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Kutzky Park, 1.6 km from Mayo Clinic
United States
Janet
SAR 413
SAR 476 total
includes taxes & fees
18 Sep - 19 Sep
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

20. Residence Inn by Marriott Rochester Mayo Clinic Area

Residence Inn by Marriott Rochester Mayo Clinic Area
Downtown Rochester, 0.2 km from Mayo Clinic
United States
Greg
SAR 597
SAR 687 total
includes taxes & fees
2 Oct - 3 Oct
Residence Inn by Marriott Rochester Mayo Clinic Area
View all properties

Compare popular hotels close to Mayo Clinic

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Lobby
The Berkman
9.6
Exceptional
432 reviews
View
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area
9.6
Exceptional
1,002 reviews
View
View from property
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
9.6
Exceptional
738 reviews
View
Pub
TownePlace Suites by Marriott Rochester Mayo Clinic Area
9.6
Exceptional
558 reviews
View
Presidential Suite, Multiple Beds | Living area | 55-inch LCD TV with satellite channels, TV
Hilton Rochester Mayo Clinic Area
9.6
Exceptional
644 reviews
View

Top Mayo Clinic Hotel Reviews

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10/10 Excellent
"The hotel and staff were great. The pool area is one of the best I've seen. It even has a small pool for the kids. The hot tub was great and he pool was warm which made it more enjoyable. Twigs restaurant on site was phenomenal. If you love ribs you have to get them. I will definitely be going back."
Shane 2-night trip
Posted 9 hours ago
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

8/10 Good
"Good"
Quynh 3-night trip
Posted 13 hours ago
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

10/10 Excellent
"Wish breakfast was included in the room price but great hotel and not too far from Mayo Clinic they do have a shuttle service"
Ashley 1-night trip
Posted 1 day ago
EVEN Hotel Rochester - Mayo Clinic Area by IHG
TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

10/10 Excellent
"It was nice. Very clean. It would be nice if in a two bedroom suite for four people staying multiple days they would supply more than two rolls of toilet paper and three towels without having to ask for more. Would also have liked extra blankets in the room. When I asked for an extra blanket I got extra sheets which didn't help the cold person. Breakfast was fine- bacon seems oddly soggy ."
Elizabeth 2-night trip
Posted 1 day ago
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

8/10 Good
"Very comfortable common spaces. It was nice to have an outdoor lounge to relax in. The bathroom was amazing and I liked the room layout"
Cynthia 1-night trip
Posted 1 day ago
Staybridge Suites Rochester - Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent
"Everything was exceptional"
James 2-night trip
Posted 1 day ago
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Aspen Select

Aspen Select

10/10 Excellent
"The room had everything we needed.Restaurant right next Door.We would return."
Claudia 2-night trip
Posted 2 days ago
Aspen Select
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

8/10 Good
"Everything"
jaime 1-night trip
Posted 3 days ago
Med City Inn & Suites - Mayo Clinic Area
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

10/10 Excellent
"Pleasant hotel - a little basic but comfortable and clean. Staff very pleasant. A buffet breakfast is available but there is no restaurant or bar."
John 5-night trip
Posted 5 days ago
Hilton Garden Inn Rochester Downtown, MN

Frequently asked questions

What's the area like around Mayo Clinic?
Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, check out the 152 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic?
Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Hotel Indigo Rochester – Mayo Clinic Area by IHG.
How many hotels will I be able to find near Mayo Clinic?
Expedia has 152 hotels and other accommodations within a mile from Mayo Clinic.
If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near Mayo Clinic.
Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic?
For additional details about rescheduling or cancelling your stay near Mayo Clinic, head over to our customer service page.
What can I see and do near Mayo Clinic?
You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Plummer House and Assisi Heights. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.