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Check prices for these dates

Tonight
8 Aug - 9 Aug
Tomorrow
9 Aug - 10 Aug
Next weekend
14 Aug - 16 Aug
In two weeks
21 Aug - 23 Aug

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Our top choices for Mayo Clinic hotels

1. TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
Kutzky Park, 0.4 km from Mayo Clinic
United States
Jorge
SAR 477
SAR 549 total
includes taxes & fees
21 Aug - 22 Aug
TownePlace Suites by Marriott Rochester Mayo Clinic Area

2. Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Jennifer
SAR 643
SAR 741 total
includes taxes & fees
21 Aug - 22 Aug
Hilton Rochester Mayo Clinic Area

3. Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
2.6 km from Mayo Clinic
United States
Timothy
SAR 459
SAR 528 total
includes taxes & fees
15 Aug - 16 Aug
Home2 Suites by Hilton Rochester Mayo Clinic Area

4. Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
2.4 km from Mayo Clinic
United States
Richard
SAR 496
SAR 571 total
includes taxes & fees
5 Sep - 6 Sep
Residence Inn by Marriott Rochester Mayo Clinic Area South

5. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Kutzky Park, 1.8 km from Mayo Clinic
United States
Marissa
SAR 453
SAR 521 total
includes taxes & fees
16 Aug - 17 Aug
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

6. The Berkman

The Berkman
Folwell, 1.4 km from Mayo Clinic
United States
Jana
SAR 703
SAR 817 total
includes taxes & fees
9 Aug - 10 Aug
The Berkman

7. EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Kutzky Park, 1 km from Mayo Clinic
United States
paul
SAR 360
SAR 466 total
includes taxes & fees
14 Aug - 15 Aug
EVEN Hotel Rochester - Mayo Clinic Area by IHG

8. The Towers At Kahler Grand Hotel

The Towers At Kahler Grand Hotel
Downtown Rochester, 0.1 km from Mayo Clinic
United States
Chris
SAR 1,348
SAR 1,552 total
includes taxes & fees
16 Aug - 17 Aug
The Towers At Kahler Grand Hotel

9. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
Kutzky Park, 1 km from Mayo Clinic
United States
Denise
SAR 417
SAR 487 total
includes taxes & fees
6 Sep - 7 Sep
Staybridge Suites Rochester - Mayo Clinic Area by IHG

10. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Kutzky Park, 1.4 km from Mayo Clinic
United States
MATTHEW
SAR 424
SAR 489 total
includes taxes & fees
15 Aug - 16 Aug
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

11. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Kutzky Park, 1.4 km from Mayo Clinic
United States
Eric
SAR 413
SAR 475 total
includes taxes & fees
15 Aug - 16 Aug
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

12. Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG
2.6 km from Mayo Clinic
United States
Sean
SAR 436
SAR 501 total
includes taxes & fees
23 Aug - 24 Aug
Candlewood Suites Rochester Mayo Clinic Area by IHG

13. Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Camille
SAR 635
SAR 731 total
includes taxes & fees
5 Sep - 6 Sep
Broadway Plaza, Trademark Collection by Wyndham

14. Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.9 km from Mayo Clinic
United States
Richard
SAR 354
SAR 408 total
includes taxes & fees
30 Aug - 31 Aug
Hampton Inn Rochester-South

15. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
3.1 km from Mayo Clinic
United States
Denise
SAR 257
SAR 296 total
includes taxes & fees
30 Aug - 31 Aug
Econo Lodge Mayo Clinic Area

16. Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
Downtown Rochester, 0.5 km from Mayo Clinic
United States
Bridgett
SAR 597
SAR 687 total
includes taxes & fees
21 Aug - 22 Aug
Hyatt House Rochester/Mayo Clinic Area

17. Aspen Suites

Aspen Suites
1.2 km from Mayo Clinic
United States
CASEY
SAR 490
SAR 592 total
includes taxes & fees
9 Aug - 10 Aug
Aspen Suites

18. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Downtown Rochester, 0.4 km from Mayo Clinic
United States
Leo
SAR 387
SAR 445 total
includes taxes & fees
21 Aug - 22 Aug
Hotel Indigo Rochester – Mayo Clinic Area by IHG

19. Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Kim
SAR 428
SAR 493 total
includes taxes & fees
5 Sep - 6 Sep
Hilton Garden Inn Rochester Downtown, MN

20. Brentwood Inn & Suites

Brentwood Inn & Suites
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Bryan
SAR 469
SAR 540 total
includes taxes & fees
12 Aug - 13 Aug
Brentwood Inn & Suites
View all properties

Compare popular hotels close to Mayo Clinic

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Pub
TownePlace Suites by Marriott Rochester Mayo Clinic Area
9.6
Exceptional
547 reviews
View
Presidential Suite, Multiple Beds | Living area | 55-inch LCD TV with satellite channels, TV
Hilton Rochester Mayo Clinic Area
9.6
Exceptional
630 reviews
View
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area
9.6
Exceptional
1,006 reviews
View
Indoor pool
Residence Inn by Marriott Rochester Mayo Clinic Area South
9.6
Exceptional
299 reviews
View
View from property
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
9.6
Exceptional
730 reviews
View

Top Mayo Clinic Hotel Reviews

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent
"The facility was clean staff was helpful and the breakfast was okay"
Marissa 6-night trip
Posted 1 hour ago
Staybridge Suites Rochester - Mayo Clinic Area by IHG
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent
"They have thought of everything, I recommend the Suites and Inn Just because everything is there for you. Things you would not think of packing ."
Rodney 2-night trip
Posted 5 hours ago
Kahler Inn and Suites - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10/10 Excellent
"Breakfast menu was fair."
Bonita 1-night trip
Posted 5 hours ago
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Aspen Suites

Aspen Suites

10/10 Excellent
"Excellent location, helpful staff, reasonable price, comfortable suite, good breakfast"
Susanna 4-night trip
Posted 20 hours ago
Aspen Suites
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

10/10 Excellent
"Close to Mayo Clinic. Good price"
Tom 2-night trip
Posted 22 hours ago
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Brentwood Inn & Suites

Brentwood Inn & Suites

8/10 Good
"Clean rooms and property. Breakfast was very basic."
Roger 2-night trip
Posted 2 days ago
Brentwood Inn & Suites
TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

10/10 Excellent
"Parking lot (underground) has very small spaces - very difficult for even an average SUV to park. Towel refresh policy unexplained and/or difficult to use."
John Ghastin 2-night trip
Posted 3 days ago
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

10/10 Excellent
"Very helpful staff, room was very clean(smelled great) and the whole facility is beautiful! Our second time staying and definitely will stay again."
Kim 1-night trip
Posted 4 days ago
Hilton Garden Inn Rochester Downtown, MN
Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

10/10 Excellent
"Everything was clean and all the workers were very nice"
Eric 2-night trip
Posted 4 days ago
Hilton Rochester Mayo Clinic Area

Frequently asked questions

What's the area like around Mayo Clinic?
Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, check out the 149 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic?
Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Med City Inn & Suites - Mayo Clinic Area.
How many hotels will I be able to find near Mayo Clinic?
Expedia has 149 hotels and other accommodations within a mile from Mayo Clinic.
If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near Mayo Clinic.
Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic?
For additional details about rescheduling or cancelling your stay near Mayo Clinic, head over to our customer service page.
What can I see and do near Mayo Clinic?
You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Plummer House and Assisi Heights. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.