A historic building with a prominent tower, two American flags, and a modern glass structure in the foreground.

Find hotels near Mayo Clinic, Rochester from SAR 305

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
11 Aug - 12 Aug
Tomorrow
12 Aug - 13 Aug
This weekend
14 Aug - 16 Aug
Next weekend
21 Aug - 23 Aug

Filter by

Star rating

Guest rating

Our top choices for Mayo Clinic hotels

1. Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
2.6 km from Mayo Clinic
United States
Timothy
SAR 459
SAR 528 total
includes taxes & fees
4 Sep - 5 Sep
Home2 Suites by Hilton Rochester Mayo Clinic Area

2. Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
2.4 km from Mayo Clinic
United States
Richard
SAR 496
SAR 571 total
includes taxes & fees
22 Aug - 23 Aug
Residence Inn by Marriott Rochester Mayo Clinic Area South

3. The Berkman

The Berkman
Folwell, 1.4 km from Mayo Clinic
United States
Jana
SAR 740
SAR 860 total
includes taxes & fees
16 Aug - 17 Aug
The Berkman

4. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Kutzky Park, 1.8 km from Mayo Clinic
United States
Marissa
SAR 470
SAR 541 total
includes taxes & fees
21 Aug - 22 Aug
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

5. TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
Kutzky Park, 0.4 km from Mayo Clinic
United States
Jorge
SAR 477
SAR 549 total
includes taxes & fees
21 Aug - 22 Aug
TownePlace Suites by Marriott Rochester Mayo Clinic Area

6. The Towers At Kahler Grand Hotel

The Towers At Kahler Grand Hotel
Downtown Rochester, 0.1 km from Mayo Clinic
United States
Chris
SAR 1,348
SAR 1,552 total
includes taxes & fees
27 Aug - 28 Aug
The Towers At Kahler Grand Hotel

7. EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Kutzky Park, 1 km from Mayo Clinic
United States
paul
SAR 349
SAR 453 total
includes taxes & fees
28 Aug - 29 Aug
EVEN Hotel Rochester - Mayo Clinic Area by IHG

8. Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Jennifer
SAR 644
SAR 741 total
includes taxes & fees
21 Aug - 22 Aug
Hilton Rochester Mayo Clinic Area

9. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
Kutzky Park, 1 km from Mayo Clinic
United States
Denise
SAR 417
SAR 487 total
includes taxes & fees
6 Sep - 7 Sep
Staybridge Suites Rochester - Mayo Clinic Area by IHG

10. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Kutzky Park, 1.4 km from Mayo Clinic
United States
MATTHEW
SAR 409
SAR 471 total
includes taxes & fees
14 Aug - 15 Aug
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

11. Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG
2.6 km from Mayo Clinic
United States
Sean
SAR 436
SAR 501 total
includes taxes & fees
14 Aug - 15 Aug
Candlewood Suites Rochester Mayo Clinic Area by IHG

12. Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Camille
SAR 635
SAR 731 total
includes taxes & fees
4 Sep - 5 Sep
Broadway Plaza, Trademark Collection by Wyndham

13. Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.9 km from Mayo Clinic
United States
Richard
SAR 354
SAR 408 total
includes taxes & fees
23 Aug - 24 Aug
Hampton Inn Rochester-South

14. Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
Downtown Rochester, 0.5 km from Mayo Clinic
United States
Bridgett
SAR 597
SAR 687 total
includes taxes & fees
13 Aug - 14 Aug
Hyatt House Rochester/Mayo Clinic Area

15. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
3.1 km from Mayo Clinic
United States
Denise
SAR 265
SAR 305 total
includes taxes & fees
6 Sep - 7 Sep
Econo Lodge Mayo Clinic Area

16. Aspen Suites

Aspen Suites
1.2 km from Mayo Clinic
United States
CASEY
SAR 504
SAR 609 total
includes taxes & fees
5 Sep - 6 Sep
Aspen Suites

17. Brentwood Inn & Suites

Brentwood Inn & Suites
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Bryan
SAR 469
SAR 540 total
includes taxes & fees
13 Aug - 14 Aug
Brentwood Inn & Suites

18. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Downtown Rochester, 0.4 km from Mayo Clinic
United States
Leo
SAR 387
SAR 445 total
includes taxes & fees
21 Aug - 22 Aug
Hotel Indigo Rochester – Mayo Clinic Area by IHG

19. Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Kim
SAR 428
SAR 493 total
includes taxes & fees
28 Aug - 29 Aug
Hilton Garden Inn Rochester Downtown, MN

20. Quality Inn & Suites Mayo Clinic Area

Quality Inn & Suites Mayo Clinic Area
2.6 km from Mayo Clinic
United States
Cassandra
SAR 287
SAR 335 total
includes taxes & fees
6 Sep - 7 Sep
Quality Inn & Suites Mayo Clinic Area
View all properties

Compare popular hotels close to Mayo Clinic

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area
9.6
Exceptional
1,006 reviews
View
Indoor pool
Residence Inn by Marriott Rochester Mayo Clinic Area South
9.6
Exceptional
299 reviews
View
Lobby
The Berkman
9.6
Exceptional
425 reviews
View
View from property
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
9.6
Exceptional
731 reviews
View
Pub
TownePlace Suites by Marriott Rochester Mayo Clinic Area
9.6
Exceptional
548 reviews
View

Top Mayo Clinic Hotel Reviews

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

10/10 Excellent
"Clean hotel close to Mayo Clinic."
Elizabeth 1-night trip
Posted 1 hour ago
EVEN Hotel Rochester - Mayo Clinic Area by IHG
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

10/10 Excellent
"Comfortable and clean!"
Janet 2-night trip
Posted 12 hours ago
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

10/10 Excellent
"The rooms were clean & well maintained. It was quiet. They have a pool, exercise room, vending machines & a small arcade. The continental breakfast was pretty extensive. Included waffles, eggs, sausage, oatmeal, cold cereal, yogurt, bread, English muffins, bagels, etc... plenty of parking and has a Famous Dave's in front. Easy access to stores, restaurant and St. Mary's/ Mayo hospital."
Gaye 1-night trip
Posted 16 hours ago
Med City Inn & Suites - Mayo Clinic Area
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent
"The room was very nice. The only thing is I wish they would keep up better with the mildew around the bathtub/shower. I just don’t like seeing it. Everything else else was really good. The breakfasts were awesome!! The restaurant attached was fabulous!!! There is quite a bit of construction in the whole Rochester area that was annoying but there is a bus shuttle service that took us to the Mayo hospital. That was very helpful because there’s not much parking. Staff is very pleasant and so helpful. Thank you!!!"
Ken 2-night trip
Posted 17 hours ago
AmericInn by Wyndham Rochester Near Mayo Clinic
TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

10/10 Excellent
"Very polite, helpful staff. Excellent room- great space!"
Jill Peterson 1-night trip
Posted 2 days ago
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

8/10 Good
"Office staff, particularly Affinity, wss extremely helpful! Major drawback was parking was oversold which seriously inconvenience guests who went out for dinner."
Kalvin 6-night trip
Posted 2 days ago
Staybridge Suites Rochester - Mayo Clinic Area by IHG
Brentwood Inn & Suites

Brentwood Inn & Suites

10/10 Excellent
"Great place to stay"
Thomas 1-night trip
Posted 2 days ago
Brentwood Inn & Suites
Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

8/10 Good
"Liked having a full couch in the room and the kitchen area made it easy for a longer stay."
Anne 4-night trip
Posted 2 days ago
Hilton Rochester Mayo Clinic Area
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

10/10 Excellent
"Very helpful staff, room was very clean(smelled great) and the whole facility is beautiful! Our second time staying and definitely will stay again."
Kim 1-night trip
Posted 7 days ago
Hilton Garden Inn Rochester Downtown, MN

Frequently asked questions

What's the area like around Mayo Clinic?
Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, check out the 149 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic?
Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Med City Inn & Suites - Mayo Clinic Area.
How many hotels will I be able to find near Mayo Clinic?
Expedia has 149 hotels and other accommodations within a mile from Mayo Clinic.
If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near Mayo Clinic.
Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic?
For additional details about rescheduling or cancelling your stay near Mayo Clinic, head over to our customer service page.
What can I see and do near Mayo Clinic?
You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Plummer House and Assisi Heights. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.