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Tonight
28 Aug - 29 Aug
Tomorrow
29 Aug - 30 Aug
This weekend
28 Aug - 30 Aug
Next weekend
4 Sep - 6 Sep

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Our top choices for Mayo Clinic hotels

1. TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
Kutzky Park, 0.4 km from Mayo Clinic
United States
Jorge
SAR 477
SAR 549 total
includes taxes & fees
4 Sep - 5 Sep
TownePlace Suites by Marriott Rochester Mayo Clinic Area

2. Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Jennifer
SAR 643
SAR 741 total
includes taxes & fees
4 Sep - 5 Sep
Hilton Rochester Mayo Clinic Area

3. Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
2.6 km from Mayo Clinic
United States
Vickie
SAR 459
SAR 528 total
includes taxes & fees
5 Sep - 6 Sep
Home2 Suites by Hilton Rochester Mayo Clinic Area

4. Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
2.4 km from Mayo Clinic
United States
Richard
SAR 514
SAR 592 total
includes taxes & fees
11 Sep - 12 Sep
Residence Inn by Marriott Rochester Mayo Clinic Area South

5. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Kutzky Park, 1.8 km from Mayo Clinic
United States
Jon
SAR 419
SAR 482 total
includes taxes & fees
3 Sep - 4 Sep
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

6. EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Kutzky Park, 1 km from Mayo Clinic
United States
paul
SAR 394
SAR 505 total
includes taxes & fees
4 Sep - 5 Sep
EVEN Hotel Rochester - Mayo Clinic Area by IHG

7. The Berkman

The Berkman
Folwell, 1.4 km from Mayo Clinic
United States
William
SAR 769
SAR 894 total
includes taxes & fees
3 Sep - 4 Sep
The Berkman

8. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
Kutzky Park, 1 km from Mayo Clinic
United States
matthew
SAR 387
SAR 453 total
includes taxes & fees
4 Sep - 5 Sep
Staybridge Suites Rochester - Mayo Clinic Area by IHG

9. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Kutzky Park, 1.4 km from Mayo Clinic
United States
MATTHEW
SAR 389
SAR 448 total
includes taxes & fees
19 Sep - 20 Sep
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

10. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Kutzky Park, 1.4 km from Mayo Clinic
United States
Lin
SAR 428
SAR 493 total
includes taxes & fees
5 Sep - 6 Sep
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

11. Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG
2.6 km from Mayo Clinic
United States
Sean
SAR 436
SAR 501 total
includes taxes & fees
27 Sep - 28 Sep
Candlewood Suites Rochester Mayo Clinic Area by IHG

12. Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Camille
SAR 635
SAR 731 total
includes taxes & fees
5 Sep - 6 Sep
Broadway Plaza, Trademark Collection by Wyndham

13. Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.9 km from Mayo Clinic
United States
Lynne
SAR 382
SAR 440 total
includes taxes & fees
7 Sep - 8 Sep
Hampton Inn Rochester-South

14. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
3.1 km from Mayo Clinic
United States
Markus
SAR 258
SAR 297 total
includes taxes & fees
20 Sep - 21 Sep
Econo Lodge Mayo Clinic Area

15. Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
Downtown Rochester, 0.5 km from Mayo Clinic
United States
Bridgett
SAR 522
SAR 601 total
includes taxes & fees
29 Aug - 30 Aug
Hyatt House Rochester/Mayo Clinic Area

16. Aspen Suites

Aspen Suites
1.2 km from Mayo Clinic
United States
Dr. suzette
SAR 476
SAR 575 total
includes taxes & fees
11 Sep - 12 Sep
Aspen Suites

17. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Downtown Rochester, 0.4 km from Mayo Clinic
United States
Kyle
SAR 349
SAR 402 total
includes taxes & fees
12 Sep - 13 Sep
Hotel Indigo Rochester – Mayo Clinic Area by IHG

18. Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Eileen
SAR 428
SAR 493 total
includes taxes & fees
4 Sep - 5 Sep
Hilton Garden Inn Rochester Downtown, MN

19. Brentwood Inn & Suites

Brentwood Inn & Suites
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Bryan
SAR 469
SAR 540 total
includes taxes & fees
30 Aug - 31 Aug
Brentwood Inn & Suites

20. Quality Inn & Suites Mayo Clinic Area

Quality Inn & Suites Mayo Clinic Area
2.6 km from Mayo Clinic
United States
Cassandra
SAR 287
SAR 335 total
includes taxes & fees
27 Sep - 28 Sep
Quality Inn & Suites Mayo Clinic Area
View all properties

Compare popular hotels close to Mayo Clinic

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Pub
TownePlace Suites by Marriott Rochester Mayo Clinic Area
9.6
Exceptional
553 reviews
View
Presidential Suite, Multiple Beds | Living area | 55-inch LCD TV with satellite channels, TV
Hilton Rochester Mayo Clinic Area
9.6
Exceptional
642 reviews
View
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area
9.6
Exceptional
1,001 reviews
View
Indoor pool
Residence Inn by Marriott Rochester Mayo Clinic Area South
9.6
Exceptional
302 reviews
View
View from property
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
9.6
Exceptional
737 reviews
View

Top Mayo Clinic Hotel Reviews

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

8/10 Good
"Stayed 5 days and didn't have 1 single problem."
Michelle 4-night trip
Posted 9 hours ago
AmericInn by Wyndham Rochester Near Mayo Clinic
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

10/10 Excellent
"This place is great! They have nice beds. Better than the Springhill Marriott. It was clean and the right price for people coming to Mayo. They don't gouge you like the other hotels do. There are plenty of food options around and a grocery store. My new favorite place to stay in Rochester."
Dawn 1-night trip
Posted 11 hours ago
Med City Inn & Suites - Mayo Clinic Area
Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent
"The staff was very helpful, friendly, and knew places to visit and eat"
matthew 1-night trip
Posted 11 hours ago
Staybridge Suites Rochester - Mayo Clinic Area by IHG
Brentwood Inn & Suites

Brentwood Inn & Suites

10/10 Excellent
"A comfortable stay close by Mayo Clinic"
Frank 2-night trip
Posted 2 days ago
Brentwood Inn & Suites
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10/10 Excellent
"We loved our stay! Staff was excellent, we will be back"
Mark 1-night trip
Posted 2 days ago
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent
"This is my first time staying at Hotel Indigo. The staff was amazing. I had to keep adding nights and they were so accommodating. The room was just right. It was clean , well stocked and easy access to the Mayo Clinic. I really liked the front desk people. Super friendly and helpful. Love the attached restaurant!"
Lori 2-night trip
Posted 4 days ago
Hotel Indigo Rochester – Mayo Clinic Area by IHG
TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

10/10 Excellent
"Great staff"
Jonas 2-night trip
Posted 5 days ago
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham

10/10 Excellent
"The space was perfect. Close to everywhere I needed. I love the pool and the workout room."
Diane 5-night trip
Posted 1 month ago
Broadway Plaza, Trademark Collection by Wyndham

Frequently asked questions

What's the area like around Mayo Clinic?
Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, check out the 150 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic?
Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Med City Inn & Suites - Mayo Clinic Area.
How many hotels will I be able to find near Mayo Clinic?
Expedia has 150 hotels and other accommodations within a mile from Mayo Clinic.
If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near Mayo Clinic.
Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic?
For additional details about rescheduling or cancelling your stay near Mayo Clinic, head over to our customer service page.
What can I see and do near Mayo Clinic?
You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Plummer House and Assisi Heights. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.