Visit South Main
Popular places to visit
Daikin Park
Daikin Park is one of the more well-known attractions to visit during your trip to Houston. Experience the lively festivals and entertainment choices in this vibrant area.
George R. Brown Convention Center
During your trip, find out what's happening at George R. Brown Convention Center, a top convention center in Houston. Experience the acclaimed art scene and lively festivals in this vibrant area.
NASA Johnson Space Center
After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.
Toyota Center
Catch an event at Toyota Center during your trip to Houston. Experience the great live music and acclaimed theater scene in this vibrant area.
Rice University
Enjoy the collegiate vibe around Rice University, a top university in Houston. Experience the area's lively festivals and acclaimed theater scene.
Houston Zoo
Why not visit the native and exotic animals at Houston Zoo and see why this is a popular attraction in Houston? Experience the area's fascinating museums and great live music.
South Main Hotel Deals
Reviewed on 23 June 2025
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Reviewed on 26 June 2025
Reviewed on 27 June 2025
Reviewed on 23 June 2025
Reviewed on 26 June 2025
Other neighborhoods around South Main
Astrodome
If you're spending time in Astrodome, check out sights like NRG Stadium or NRG Arena and hop on the metro to see more the city at Stadium Park/Astrodome Station or Smith Lands Station.
Texas Medical Center
Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.
Houston Museum District
Known for its ample dining options and fascinating museums, there's plenty to explore in Houston Museum District. You can visit top attractions like Houston Zoo and Children's Museum of Houston, and jump on the metro at M. D. Anderson Station or Museum District Station to see more of the city.
South Central Houston
If you're spending time in South Central Houston, check out sights like Houston Zoo or Children's Museum of Houston and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.
The Galleria
Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.
- NRG Stadium
- MD Anderson Cancer Center
- Daikin Park
- George R. Brown Convention Center
- Toyota Center
- Rice University
- Houston Zoo
- University of Houston
- Westheimer Rd
- Downtown Aquarium
- Memorial City Mall
- NRG Park
- CityCentre
- Smart Financial Centre at Sugar Land
- Sugar Land Town Square
- Discovery Green
- Children's Museum of Houston
- NRG Center
- Houston Natural Science Museum
- Hermann Park
- House of Blues Houston
- Baybrook Mall
- The Galleria
- Texas Children's Hospital
- Sam Houston Race Park
- Hobby Center for the Performing Arts
- Memorial Hermann Memorial City Medical Center
- Greenway Plaza
- Pearland Town Center
- Greenspoint Mall
- Houston Methodist Hospital
- Port of Houston