South Central Houston, TX
Houston





Visit South Central Houston
Popular places to visit

MD Anderson Cancer Center
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.

Rice University
Enjoy the collegiate vibe around Rice University, a top university in Houston. Experience the area's acclaimed art scene and great live music.

Houston Zoo
Why not visit the native and exotic animals who call Houston Zoo home during your trip to Houston? Experience the area's fascinating museums and lively festivals.

University of Houston
Enjoy the collegiate vibe when you visit University of Houston, during your travels in Houston. Experience the acclaimed theater scene and lively festivals in this vibrant area.

Children's Museum of Houston
You can take time to visit Children's Museum of Houston during your travels to Houston. Experience the area's entertainment choices and acclaimed theater scene.

Houston Methodist Hospital
Though Houston Methodist Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
South Central Houston Hotel Deals

Hotel Zaza Houston Museum District
Great place!
Reviewed on 22 April 2026

Hilton Houston Plaza/Medical Center
Everything was as always clean. Staff was very helpful when needed. Felt nice and high end
Reviewed on 22 April 2026

InterContinental Houston by IHG
Beautiful property
Reviewed on 22 April 2026

The Westin Houston Medical Center/Museum District
The staff was very delightful, room was exactly what I expected plus more. Clean room, bed was so comfortable. Valet top tier!
Reviewed on 17 April 2026

Extended Stay America Suites Houston Med Ctr Braeswood Bl
Parking was fine. Room temperature was easily controlled. The room we checked in for had a problem, but the front desk took care of giving us another room very easily and quickly. No complaints from us.
Reviewed on 22 April 2026

Houston Marriott Medical Center/Museum District
The hotel is very well-maintained and our room was clean and comfortable. The valet service for the shuttle was excellent with everyone involved giving special consideration to the passengers, most of whom were in Houston for medical reasons and were being transported to the various hospitals within ...
Reviewed on 13 April 2026
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Other neighborhoods around South Central Houston

Greater Third Ward
While you're in Greater Third Ward, take in top sights like Barbara Jordan & Mickey Leland Archives or Fertitta Center, and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.

Midtown
Characterized by a vibrant nightlife and young residents, this central Houston neighborhood boasts Ensemble Theatre, the largest African-American theater company in the US, and various parks like Midtown Park and Elizabeth Baldwin Park. Easily accessible via METRORail Red Line.

East Downtown Houston
Get to know East Downtown Houston and its many features like its restaurants and live music. You might want to explore sights like Shell Energy Stadium and Giant Beatles Statues, and you can jump on the metro at Leeland/Third Ward Station or EaDo/Stadium Station to get around the city.

Museum District
Known for its ample dining options and fascinating museums, there's plenty to explore in Museum District. You can visit top attractions like Children's Museum of Houston and Houston Natural Science Museum, and jump on the metro at Museum District Station or Hermann Park/Rice U Station to see more of the city.

Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.

Downtown Houston
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
