Find Luxury Hotels in Southern Minnesota, MN
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Pick from 50 Southern Minnesota Luxury Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.
Brentwood Inn & Suites
Brentwood Inn & Suites
8.6 out of 10, Excellent, (1001)
The price is SAR 446
SAR 514 total
includes taxes & fees
24 Jum. I - 25 Jum. I
Aspen Select
Aspen Select
8.6 out of 10, Excellent, (1000)
The price is SAR 422
SAR 530 total
includes taxes & fees
24 Jum. I - 25 Jum. I
AmericInn by Wyndham Northfield
AmericInn by Wyndham Northfield
8.4 out of 10, Very Good, (455)
The price is SAR 353
SAR 388 total
includes taxes & fees
30 Jum. I - 31 Jum. I
Kahler Grand Hotel
Kahler Grand Hotel
8.2 out of 10, Very Good, (1003)
The price is SAR 559
SAR 643 total
includes taxes & fees
24 Jum. I - 25 Jum. I
AmericInn by Wyndham Blue Earth
AmericInn by Wyndham Blue Earth
8.0 out of 10, Very Good, (358)
The price is SAR 334
SAR 369 total
includes taxes & fees
24 Jum. I - 25 Jum. I
Super 8 by Wyndham Jackson MN
Super 8 by Wyndham Jackson MN
8.0 out of 10, Very Good, (430)
The price is SAR 260
SAR 284 total
includes taxes & fees
28 Jum. I - 29 Jum. I
Med City Inn & Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area
7.8 out of 10, Good, (1000)
Days Inn by Wyndham Winona
Days Inn by Wyndham Winona
7.8 out of 10, Good, (1000)
The price is SAR 251
SAR 280 total
includes taxes & fees
26 Jum. I - 27 Jum. I
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
7.6 out of 10, Good, (1201)
The price is SAR 435
SAR 501 total
includes taxes & fees
24 Jum. I - 25 Jum. I
Days Inn & Suites by Wyndham Rochester Mayo Clinic South
Days Inn & Suites by Wyndham Rochester Mayo Clinic South
7.4 out of 10, Good, (1002)
The price is SAR 233
SAR 268 total
includes taxes & fees
23 Jum. II - 24 Jum. II
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Southern Minnesota hotelsExpedia verified reviews
5/5 Excellent
Great Location/Value
"The location is amazing—just a block or two from the Mayo facilities. The price was great. As they say in real estate: location, location, location."
A verified traveler stayed at Kahler Inn and Suites - Mayo Clinic Area
Posted 2 days ago
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Hotels near popular Southern Minnesota Attractions
- Hotels near Mayo Clinic
- Hotels near Mayo Clinic Hospital - Saint Marys Campus
- Hotels near Treasure Island Casino
- Hotels near Minnesota State University
- Hotels near Mayo Civic Center
- Hotels near Lake Pepin
- Hotels near Apache Mall
- Hotels near Mayo Clinic Health System Event Center
- Hotels near Forestville Mystery Cave State Park
- Hotels near Lake Shetek State Park
Southern Minnesota Hotels by Star Rating
Explore more hotels
- Aspen Select
- TownePlace Suites by Marriott Rochester Mayo Clinic Area
- Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
- Brentwood Inn & Suites
- AmericInn by Wyndham Mankato Event Center
- The Plaza Hotel & Suites Winona
- Motel 6 Mankato, MN
- Country Inn & Suites by Radisson, Albert Lea, MN
- Express Suites Riverport Inn & Suites
- St James Hotel, a Historic Hotel of America
- Quality Inn & Suites
- Boarders Inn & Suites by Cobblestone Hotels - Faribault
- Microtel Inn & Suites by Wyndham Mankato
- Super 8 by Wyndham Winona MN
- Ramada by Wyndham Albert Lea
- EverSpring Inn & Suites
- Nichols Inn of Red Wing
- Country Inn & Suites by Radisson, Red Wing, MN
- AmericInn by Wyndham Northfield
- AmericInn by Wyndham Marshall