Photo by Jessica Richter

Find Luxury Hotels in Southeast Missouri, MO

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Pick from 12 Southeast Missouri Luxury Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Historical Kage House
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
10.0 out of 10, Exceptional, (202)
"beautiful place. great location. recommend to anyone"
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Pool
Drury Inn & Suites Sikeston, MO
3.0 star property
9.4 out of 10, Exceptional, (1001)
"Convenient location and newer facility compared to other area options."
The price is SAR 371
SAR 421 total
includes taxes & fees
2 Jum. II - 3 Jum. II
Drury Inn & Suites Sikeston, MO
Exterior
Drury Inn & Suites Cape Girardeau
3.0 star property
9.4 out of 10, Exceptional, (787)
"The staff were very friendly."
The price is SAR 405
SAR 457 total
includes taxes & fees
30 Jum. I - 31 Jum. I
Drury Inn & Suites Cape Girardeau
Exterior
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
9.0 out of 10, Wonderful, (1002)
"We liked that it was close to everything we needed."
The price is SAR 253
SAR 286 total
includes taxes & fees
30 Jum. I - 31 Jum. I
Pear Tree Inn Cape Girardeau Near the Medical Center
Front of property
Motel 6 Poplar Bluff, MO
2.0 star property
8.0 out of 10, Very Good, (1008)
"Great location. Great price "
The price is SAR 267
SAR 281 total
includes taxes & fees
5 Jum. II - 6 Jum. II
Motel 6 Poplar Bluff, MO
Exterior
Comfort Inn Festus - St Louis South
2.5 star property
8.0 out of 10, Very Good, (692)
"Clean and affordable "
The price is SAR 358
SAR 418 total
includes taxes & fees
5 Jum. II - 6 Jum. II
Comfort Inn Festus - St Louis South
Room
Days Inn and Suites by Wyndham Sikeston
2.0 star property
7.0 out of 10, Good, (1004)
"Great value and super quiet. "
The price is SAR 258
SAR 287 total
includes taxes & fees
2 Jum. II - 3 Jum. II
Days Inn and Suites by Wyndham Sikeston
Exterior
Quality Inn Festus
3.0 star property
7.0 out of 10, Good, (871)
"We explicitly look for places with hotel bars and they listed as having one and they haven’t had one in years according to the clerk - very disappointing "
Quality Inn Festus
Exterior
Quality Inn
2.5 star property
7.0 out of 10, Good, (467)
"I just wanted a place to sleep. So i wasn't expecting "fancy", but for the price of the rooms, they need to be clean and dust free, with no broken walls. I forgot to take a picture, but the patch job they did to cover the hole from the bathroom door knob still had the visible crack line. The room had a 2 door micro refrigerator that was hid behind the door of the "entertainment center", and the coffee pouch was just one regular, and 2 decaffeinated, so for my second cup of coffee I used both...
The price is SAR 251
SAR 284 total
includes taxes & fees
27 Jum. I - 28 Jum. I
Quality Inn
Exterior
Super 8 by Wyndham Poplar Bluff Missouri
2.0 star property
6.6 out of 10, (466)
"Only stopped for a quick layover. Room was fine, bathroom was in pretty rough shape. Everything in the area seems new, hotel needs a remodel."
The price is SAR 240
SAR 271 total
includes taxes & fees
5 Jum. II - 6 Jum. II
Super 8 by Wyndham Poplar Bluff Missouri
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent reviews of Southeast Missouri hotels
Expedia verified reviews

Quality Inn

Quality Inn

5/5 Excellent
Room review
"I just wanted a place to sleep. So i wasn't expecting "fancy", but for the price of the rooms, they need to be clean and dust free, with no broken walls. I forgot to take a picture, but the patch job they did to cover the hole from the bathroom door knob still had the visible crack line. The room had a 2 door micro refrigerator that was hid behind the door of the "entertainment center", and the coffee pouch was just one regular, and 2 decaffeinated, so for my second cup of coffee I used both decaf pouches. My bad was i didn't read the rules beforehand and they aren't pet friendly except for service animals and i was in town for a animal auction. "
A verified traveler stayed at Quality Inn
Posted 2 days ago
Quality Inn