Default HTG hotel image

Hotels near San Diego Santa Fe Depot

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for San Diego Santa Fe Depot hotels

A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

1. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
1.9 km from San Diego Santa Fe Depot
9.6 out of 10, Exceptional, (220 reviews)
"Friendly staff!"
United States
Donavin
The price is SAR 437
SAR 620 total
includes taxes & fees
4 Nov - 5 Nov
City24 Hotel Little Italy Mission Hills
A hotel room with a herringbone-patterned floor, a bed, a chair, and curtains with room numbers.

2. Stay Classy Hostel

Stay Classy Hostel
2.0 star property
East Village, 1.8 km from San Diego Santa Fe Depot
9.6 out of 10, Exceptional, (967 reviews)
"A place to sleep with a nice bathing facility. All I needed while exploring the area."
United States
Andrew
The price is SAR 203
SAR 231 total
includes taxes & fees
11 Oct - 12 Oct
Stay Classy Hostel
A living room with a round table, a blue sofa, a patterned armchair, and a potted plant.

3. Crown City Inn

Crown City Inn
2.5 star property
2.7 km from San Diego Santa Fe Depot
9.6 out of 10, Exceptional, (853 reviews)
"Amazing Stay!"
United States
Guillaume
The price is SAR 732
SAR 805 total
includes taxes & fees
12 Oct - 13 Oct
Crown City Inn
A rooftop pool with lounge chairs and a city skyline in the background.

4. Kasa Little Italy San Diego

Kasa Little Italy San Diego
4.5 star property
0.4 km from San Diego Santa Fe Depot
9.6 out of 10, Exceptional, (541 reviews)
"Perfect location, great pool, beds were comfy. No complaints"
United States
Jeremy
The price is SAR 828
SAR 1,273 total
includes taxes & fees
25 Oct - 26 Oct
Kasa Little Italy San Diego
A modern bedroom with a brick wall, a bed, a desk, and a seating area.

5. Keating Hotel By At Mine Hospitality

Keating Hotel By At Mine Hospitality
2.0 star property
East Village, 1.2 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (196 reviews)
"Great place to stay that is right in downtown."
United States
Jessica
The price is SAR 180
SAR 500 total
includes taxes & fees
7 Oct - 8 Oct
Keating Hotel By At Mine Hospitality
A modern indoor space with a central reflective sculpture, surrounded by planters and a brick wall.

6. Hotel Narcissus

Hotel Narcissus
2.0 star property
2.9 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (37 reviews)
"Excellent little quirky hotel that is very well taken care of. Great stay!"
United States
Gene
The price is SAR 239
SAR 648 total
includes taxes & fees
20 Oct - 21 Oct
Hotel Narcissus
A high-rise hotel with multiple floors, a prominent sign at the top, and a well-lit facade.

7. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
1.1 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (1,238 reviews)
"Great for traveling families."
United States
Veronica Dangerfield
The price is SAR 698
SAR 810 total
includes taxes & fees
25 Oct - 26 Oct
Marriott Vacation Club®, San Diego
A luxurious room with a grand piano, plush blue sofas, ornate chandeliers, and elegant decor.

8. Westgate Hotel

Westgate Hotel
4.5 star property
0.6 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (1,048 reviews)
"Great location. Helpful staff."
United States
Arlet
The price is SAR 619
SAR 848 total
includes taxes & fees
25 Oct - 26 Oct
Westgate Hotel
A modern bar area with a curved counter, multiple bar stools, and a large window offering a view of the cityscape.

9. Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Gaslamp Quarter, 1.4 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (2,402 reviews)
"Location was great beautiful view of the bay room was clean and setup nicely"
United States
Shari
The price is SAR 1,069
SAR 1,410 total
includes taxes & fees
24 Oct - 25 Oct
Omni San Diego Hotel at the Ballpark
A spacious dining area with high ceilings, large chandeliers, and a modern interior design.

10. Pendry San Diego

Pendry San Diego
5.0 star property
Gaslamp Quarter, 1.2 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (1,005 reviews)
"Nice hotel"
United States
Halil
The price is SAR 1,107
SAR 1,490 total
includes taxes & fees
27 Oct - 28 Oct
Pendry San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to San Diego Santa Fe Depot

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.
City24 Hotel Little Italy Mission Hills
4.5 star property
9.6
Exceptional
220 reviews
View
A hotel room with a herringbone-patterned floor, a bed, a chair, and curtains with room numbers.
Stay Classy Hostel
2.0 star property
9.6
Exceptional
967 reviews
View
A living room with a round table, a blue sofa, a patterned armchair, and a potted plant.
Crown City Inn
2.5 star property
9.6
Exceptional
853 reviews
View
A rooftop pool with lounge chairs and a city skyline in the background.
Kasa Little Italy San Diego
4.5 star property
9.6
Exceptional
541 reviews
View
A modern bedroom with a brick wall, a bed, a desk, and a seating area.
Keating Hotel By At Mine Hospitality
2.0 star property
9.4
Exceptional
196 reviews
View

Top San Diego Santa Fe Depot Hotel Reviews

Handlery Hotel

Handlery Hotel

8/10 Good
"The room was dusty and had lots of spiderwebs the patio/ balcony was dirty full of leaves the carpet was not vacuumed and the bathroom tub was rusty"
Daniela 2-night trip
Posted 2 hours ago
Handlery Hotel

Frequently asked questions

What's the area like around San Diego Santa Fe Depot?

San Diego Santa Fe Depot is located in a scenic area of San Diego known for its array of dining options and popular zoo. If you're looking for a convenient place to stay, check out the 941 hotels and other accommodations located within a mile of the station.

What's the best hotel to stay close to San Diego Santa Fe Depot?

Adjacent to San Diego Santa Fe Depot, Wyndham San Diego Bayside is one of the top choices for your stay based on our traveler data, and this hotel offers 3 restaurants and an outdoor pool. Other good options close by include Manchester Grand Hyatt San Diego and Hard Rock Hotel San Diego.

How many hotels will I find close to San Diego Santa Fe Depot?

Expedia has 941 hotels and other accommodations within a mile from the station.

What can I see and do near San Diego Santa Fe Depot?

Study the collections at USS Midway Museum, Maritime Museum of San Diego, or San Diego Natural History Museum. Hotel del Coronado, Star of India, and California Tower are monuments to see when you're exploring the area around San Diego Santa Fe Depot. You can watch performances at San Diego Civic Theatre, The Rady Shell at Jacobs Park, and Old Globe Theater if you're interested in local theater.