Find Luxury Hotels in Panama City

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Pick from 48 Panama City Luxury Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Bristol Panama, a Registry Collection Hotel
5.0 star property
9.2 out of 10, Wonderful, (1001)
"The best parts were cleanliness, and one of the best restaurants he 5th floor. The food was outstanding. "
The price is SAR 677
SAR 744 total
includes taxes & fees
6 Jum. II - 7 Jum. II
Bristol Panama, a Registry Collection Hotel
American Trade Hotel
4.5 star property
9.2 out of 10, Wonderful, (394)
"It’s a perfect location with museums, restaurants and shopping all within minutes!!"
The price is SAR 1,009
SAR 1,110 total
includes taxes & fees
1 Raj. - 2 Raj.
American Trade Hotel
Plaza Paitilla Inn Hotel
3.5 star property
9.2 out of 10, Wonderful, (1406)
"The pool is great for swimmers snd non swimmers. Very good buffet breakfast with daily variety. "
The price is SAR 439
SAR 483 total
includes taxes & fees
9 Jum. II - 10 Jum. II
Plaza Paitilla Inn Hotel
Waldorf Astoria Panama
5.0 star property
9.0 out of 10, Wonderful, (941)
"Overall nice staff and property but could use some upgrades"
The price is SAR 687
SAR 756 total
includes taxes & fees
14 Jum. II - 15 Jum. II
Waldorf Astoria Panama
Marriott Panama Hotel
4.0 star property
9.0 out of 10, Wonderful, (1003)
"Excelente servicio y muy buena localizacion"
The price is SAR 539
SAR 584 total
includes taxes & fees
1 Jum. II - 2 Jum. II
Marriott Panama Hotel
Global Hotel Panama
4.5 star property
9.0 out of 10, Wonderful, (458)
"Love it"
Global Hotel Panama
Hotel Riu Plaza Panama
5.0 star property
9.0 out of 10, Wonderful, (2492)
"Nice"
The price is SAR 397
SAR 437 total
includes taxes & fees
16 Jum. II - 17 Jum. II
Hotel Riu Plaza Panama
TRYP by Wyndham Panamá Centro
3.5 star property
9.0 out of 10, Wonderful, (1002)
"Convenient location. Good restaurant. Nice rooms. Just wish the rooms were better insulated… very noisy."
The price is SAR 307
SAR 338 total
includes taxes & fees
11 Jum. II - 12 Jum. II
TRYP by Wyndham Panamá Centro
Toscana Inn
3.5 star property
9.0 out of 10, Wonderful, (698)
"Very nice and accommodating staff. They went above and beyond to make our stay comfortable. Will definitely book with them again."
The price is SAR 232
SAR 255 total
includes taxes & fees
29 Jum. II - 30 Jum. II
Toscana Inn
JW Marriott Panama
5.0 star property
8.8 out of 10, Excellent, (1003)
"Property was great "
The price is SAR 837
SAR 907 total
includes taxes & fees
21 Jum. II - 22 Jum. II
JW Marriott Panama
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Panama City?
Arrange a flight into Panama City (PAC-Marcos A. Gelabert Intl.) Airport or Balboa (BLB-Panama Pacifico Intl.) Airport, and then treat yourself to a stay at one of 22 luxurious hotels. Known for its casinos and shopping, Panama City also has some interesting things to see and do including Albrook Shopping Mall, so you may want to take in the local sights during your visit.
How many luxury hotels will I be able to find in Panama City?
Lie in the lap of luxury during your getaway to Panama City in one of Expedia’s 22 luxury hotels.
When can I expect good weather in Panama City?
Planning for the weather is a good way to make your trip to Panama City relaxing and enjoyable, especially when you’re splurging. The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Panama City are July, August, June, and November, with each month seeing an average of 15 inches of rainfall.
What's there to see and do in Panama City?
Experience Panama City and visit Albrook Shopping Mall, Via Espana, and Iglesia del Carmen. If you have spare time during your trip, you might want to make a stop at Uruguay Street and Crown Casino.
How can I get around Panama City?
It’s easier to get around town in style when you know your options. You can walk to nearby metro stations including Iglesia del Carmen Station, Vía Argentina, and Santo Tomas Station. If you want to venture outside of the area, hop on a train at Panama City Passenger Station.

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