Find hotels near Palmdale Regional Medical Center, Palmdale from SARĀ 311

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
7 Nov - 8 Nov
Tomorrow
8 Nov - 9 Nov
Next weekend
13 Nov - 15 Nov
In two weeks
20 Nov - 22 Nov

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Palmdale Regional Medical Center hotels

An outdoor patio area with a fire pit, seating, and a covered section with tables and chairs.

1. Towneplace Suites By Marriott Palmdale

Towneplace Suites By Marriott Palmdale
2.0 star property
1.5 km from Palmdale Regional Medical Center
9.4 out of 10, Exceptional, (56 reviews)
"large room, comfortable bed."
United States
David
The price is SARĀ 372
SARĀ 416 total
includes taxes & fees
27 Nov - 28 Nov
Towneplace Suites By Marriott Palmdale
A modern kitchen with a dining area, large windows, and an outdoor patio.

2. DoubleTree by Hilton Palmdale, CA

DoubleTree by Hilton Palmdale, CA
4.0 star property
1 km from Palmdale Regional Medical Center
9.2 out of 10, Wonderful, (962 reviews)
"Loved our stay, very clean and comfortable! Highly recommend this property."
United States
Elizabeth
The price is SARĀ 397
SARĀ 446 total
includes taxes & fees
4 Dec - 5 Dec
DoubleTree by Hilton Palmdale, CA
A modern living room with a stone fireplace, a flat-screen TV, and a dining area with a wooden table and chairs.

3. Fairfield Inn & Suites by Marriott Palmdale West

Fairfield Inn & Suites by Marriott Palmdale West
3.0 star property
3 km from Palmdale Regional Medical Center
9.2 out of 10, Wonderful, (653 reviews)
"The room was nice, the property was clean, and the staff was friendly and helpful. I would stay here again"
United States
Amanda
The price is SARĀ 368
SARĀ 413 total
includes taxes & fees
15 Nov - 16 Nov
Fairfield Inn & Suites by Marriott Palmdale West
A spacious lobby with a high ceiling, a central spiral staircase, and potted plants.

4. Embassy Suites Palmdale

Embassy Suites Palmdale
3.5 star property
1.8 km from Palmdale Regional Medical Center
9.2 out of 10, Wonderful, (1,296 reviews)
"Itā€™s a good place to stay."
United States
Ruben
The price is SARĀ 459
SARĀ 515 total
includes taxes & fees
14 Nov - 15 Nov
Embassy Suites Palmdale
A modern hotel lobby with a large dining area, comfortable seating, and large windows offering a view of the outdoor patio.

5. Element by Marriott Palmdale

Element by Marriott Palmdale
3.0 star property
1.7 km from Palmdale Regional Medical Center
9.2 out of 10, Wonderful, (782 reviews)
"We enjoyed our stay! Very clean rooms and bathroom"
United States
Umenzimuhle
The price is SARĀ 412
SARĀ 462 total
includes taxes & fees
28 Nov - 29 Nov
Element by Marriott Palmdale
An outdoor patio with tables and chairs, a covered seating area, and a view of the surrounding landscape.

6. Home2 Suites by Hilton Palmdale, CA

Home2 Suites by Hilton Palmdale, CA
3.0 star property
0.9 km from Palmdale Regional Medical Center
9.0 out of 10, Wonderful, (431 reviews)
"The weekend staff were amazing!"
United States
Carlos
The price is SARĀ 412
SARĀ 463 total
includes taxes & fees
13 Nov - 14 Nov
Home2 Suites by Hilton Palmdale, CA
A modern living room with a fireplace, leather armchairs, and a dining area in the background.

7. Residence Inn by Marriott Palmdale Lancaster

Residence Inn by Marriott Palmdale Lancaster
3.0 star property
2.2 km from Palmdale Regional Medical Center
9.0 out of 10, Wonderful, (471 reviews)
"Always a great stay !! Very friendly and helpful staff, great rooms, a lot of places to eat nearby."
United States
Greg
The price is SARĀ 436
SARĀ 488 total
includes taxes & fees
23 Nov - 24 Nov
Residence Inn by Marriott Palmdale Lancaster
A multi-story hotel with a central entrance, surrounded by landscaped areas and palm trees.

8. Holiday Inn Palmdale-Lancaster by IHG

Holiday Inn Palmdale-Lancaster by IHG
3.0 star property
0.8 km from Palmdale Regional Medical Center
8.8 out of 10, Excellent, (1,004 reviews)
"It was a comfortable stay"
United States
Carlos Alberto
The price is SARĀ 312
SARĀ 350 total
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Palmdale-Lancaster by IHG
A modern hotel lobby with a central reception desk, circular ceiling lights, and a view of the outside through large glass doors.

9. Hilton Garden Inn Palmdale

Hilton Garden Inn Palmdale
3.0 star property
3 km from Palmdale Regional Medical Center
8.8 out of 10, Excellent, (1,002 reviews)
"Just an overnighter, but we agreed weā€™d stay here again. Very nice and convenient location to many dinner spots."
United States
William
The price is SARĀ 366
SARĀ 410 total
includes taxes & fees
13 Nov - 14 Nov
Hilton Garden Inn Palmdale
A courtyard with a stone fire pit surrounded by wicker furniture, a building with a sign reading "Courtyard," and a view of palm trees and a sunset sky.

10. Courtyard by Marriott Palmdale

Courtyard by Marriott Palmdale
3.0 star property
2.1 km from Palmdale Regional Medical Center
8.8 out of 10, Excellent, (1,002 reviews)
"Great place to stay."
United States
Josephine
The price is SARĀ 368
SARĀ 412 total
includes taxes & fees
23 Nov - 24 Nov
Courtyard by Marriott Palmdale
A Staybridge Suites hotel with a brick facade, multiple windows, and a central entrance.

11. Staybridge Suites Palmdale by IHG

Staybridge Suites Palmdale by IHG
3.0 star property
0.8 km from Palmdale Regional Medical Center
8.6 out of 10, Excellent, (786 reviews)
"Honestly, I don't have nothing to complain about it.The room it was super clean , thank you."
United States
Pedro
The price is SARĀ 379
SARĀ 425 total
includes taxes & fees
9 Nov - 10 Nov
Staybridge Suites Palmdale by IHG
A hotel with a red-tiled roof, multiple balconies, and a parking lot with several cars.

12. Best Western Plus John Jay Inn & Suites

Best Western Plus John Jay Inn & Suites
2.5 star property
0.5 km from Palmdale Regional Medical Center
8.6 out of 10, Excellent, (1,004 reviews)
"Great stay"
United States
Julio
The price is SARĀ 351
SARĀ 394 total
includes taxes & fees
15 Nov - 16 Nov
Best Western Plus John Jay Inn & Suites
A modern hotel with a flat roof, multiple windows, and a parking lot.

13. Woodspring Suites Palmdale - Lancaster

Woodspring Suites Palmdale - Lancaster
2.5 star property
3 km from Palmdale Regional Medical Center
8.4 out of 10, Very good, (430 reviews)
"Great place, good location, safe and friendly."
United States
Elaine
The price is SARĀ 353
SARĀ 396 total
includes taxes & fees
8 Nov - 9 Nov
Woodspring Suites Palmdale - Lancaster
A modern conference room with a long table, several chairs, and a coffee station.

14. Hampton Inn & Suites Palmdale

Hampton Inn & Suites Palmdale
2.5 star property
2 km from Palmdale Regional Medical Center
8.4 out of 10, Very good, (1,000 reviews)
"Room was clean, breakfast was good. Staff was super nice and attentive."
United States
Griselda
The price is SARĀ 305
SARĀ 349 total
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn & Suites Palmdale
A hotel room with two beds, a headboard with integrated lighting, and a patterned curtain.

15. Motel 6 Palmdale, CA

Motel 6 Palmdale, CA
2.0 star property
1 km from Palmdale Regional Medical Center
7.0 out of 10, Good, (413 reviews)
"Roaches 3 different critters in one room. Switched to a different room saw another critter. Linen wasnā€™t the cleanest either. Price is decent, best thing about the experience but you definitely get what you pay for."
United States
Donteona
The price is SARĀ 285
SARĀ 320 total
includes taxes & fees
8 Nov - 9 Nov
Motel 6 Palmdale, CA
A hotel room with two single beds, a small desk with a television, and a bathroom visible through an open door.

16. Palm Inn & Suites Palmdale Lancaster

Palm Inn & Suites Palmdale Lancaster
2.5 star property
0.8 km from Palmdale Regional Medical Center
7.0 out of 10, Good, (1,323 reviews)
"Itā€™s was over all good experience, close by freeways and good for a decent room to sleep shower so not as expensive for a night, gas stations are close by and right next to freeways"
United States
Justine
The price is SARĀ 213
SARĀ 315 total
includes taxes & fees
8 Nov - 9 Nov
Palm Inn & Suites Palmdale Lancaster
A hotel lobby with a leather sofa, a wooden coffee table, and a red vase with flowers.

17. Red Roof Inn Palmdale - Lancaster

Red Roof Inn Palmdale - Lancaster
2.0 star property
1.4 km from Palmdale Regional Medical Center
5.4 out of 10, (1,001 reviews)
"Great time"
United States
Jesus
The price is SARĀ 248
SARĀ 277 total
includes taxes & fees
1 Dec - 2 Dec
Red Roof Inn Palmdale - Lancaster
A hotel reception area with a white brick counter, a door with a red decorative panel, and a view of the street outside.

18. Hotel Palmdale - Antelope Valley

Hotel Palmdale - Antelope Valley
2.0 star property
1.8 km from Palmdale Regional Medical Center
5.2 out of 10, (320 reviews)
"Great place to stay"
United States
Pierre
The price is SARĀ 220
SARĀ 268 total
includes taxes & fees
22 Nov - 23 Nov
Hotel Palmdale - Antelope Valley
An outdoor seating area with tables and chairs, a stone facade, and a clear sky.

19. Fairfield Inn & Suites by Marriott Lancaster Palmdale

Fairfield Inn & Suites by Marriott Lancaster Palmdale
3.0 star property
11.1 km from Palmdale Regional Medical Center
9.4 out of 10, Exceptional, (948 reviews)
"Clean room helpful staff great breakfastā€™!"
United States
Juliette
The price is SARĀ 420
SARĀ 465 total
includes taxes & fees
12 Nov - 13 Nov
Fairfield Inn & Suites by Marriott Lancaster Palmdale
An outdoor patio with stone walls, a grill, a fireplace, and wicker furniture.

20. TownePlace Suites by Marriott Lancaster, CA

TownePlace Suites by Marriott Lancaster, CA
3.0 star property
11.2 km from Palmdale Regional Medical Center
9.4 out of 10, Exceptional, (444 reviews)
"Staff super nice. Room was clean and felt very welcoming."
United States
Ramel
The price is SARĀ 453
SARĀ 501 total
includes taxes & fees
15 Nov - 16 Nov
TownePlace Suites by Marriott Lancaster, CA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Palmdale Regional Medical Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
An outdoor patio area with a fire pit, seating, and a covered section with tables and chairs.
Towneplace Suites By Marriott Palmdale
2.0 star property
9.4
Exceptional
56 reviews
View
A modern kitchen with a dining area, large windows, and an outdoor patio.
DoubleTree by Hilton Palmdale, CA
4.0 star property
9.2
Wonderful
962 reviews
View
A modern living room with a stone fireplace, a flat-screen TV, and a dining area with a wooden table and chairs.
Fairfield Inn & Suites by Marriott Palmdale West
3.0 star property
9.2
Wonderful
653 reviews
View
A spacious lobby with a high ceiling, a central spiral staircase, and potted plants.
Embassy Suites Palmdale
3.5 star property
9.2
Wonderful
1,296 reviews
View
A modern hotel lobby with a large dining area, comfortable seating, and large windows offering a view of the outdoor patio.
Element by Marriott Palmdale
3.0 star property
9.2
Wonderful
782 reviews
View

Top Palmdale Regional Medical Center Hotel Reviews

A spacious lobby with a high ceiling, a central spiral staircase, and potted plants.
Embassy Suites Palmdale

Embassy Suites Palmdale

Embassy Suites Palmdale
Palmdale

10/10 Excellent

Room was very clean. Staff was very welcoming. My family will continue to book and stay at Embassayā€™s!!
United States
Stephanie
Reviewed November 5, 2026
Embassy Suites Palmdale

Frequently Asked Questions

What's the area like around Palmdale Regional Medical Center?

Palmdale Regional Medical Center is located in a welcoming area of Palmdale known for its array of dining options. If you're looking for a convenient place to stay, check out the 37 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Palmdale Regional Medical Center?

Staybridge Suites Palmdale by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. It's located just a short 0.5 mi (0.8 km) from Palmdale Regional Medical Center. Another good choice is Palms Inn & Suites, located just 0.5 mi (0.8 km) away.

How many hotels will I find close to Palmdale Regional Medical Center?

Expedia has 37 hotels and other accommodations within a mile from Palmdale Regional Medical Center.

If I need to cancel the hotel reservation for my stay near Palmdale Regional Medical Center, will I receive a refund?

Yes! The majority of hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best options available near Palmdale Regional Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Palmdale Regional Medical Center?

To access more information about changing or cancelling your stay near Palmdale Regional Medical Center, go to https://www.expedia.com/service/.

What can I see and do near Palmdale Regional Medical Center?

You can enjoy live performances at Palmdale Amphitheater and Palmdale Playhouse. If you have some time to wander around the area, you might stop by Antelope Valley Country Club, Rancho Vista Golf Club, or Desert Aire Golf Course. If you want to see more of the surrounding area, you can plan a visit to Antelope Valley Mall and Palmdale City Hall.