Find Resorts & Hotels with Spas in Big Pine Key, FL

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Check availability on Big Pine Key Resorts & Hotels with Spas

Top Big Pine Key Resorts & Hotels with Spas

Old Wooden Bridge Resort and Marina
2 Bedroom Aqua Lodge # 13 Barracuda | Living area | Flat-screen TV

Old Wooden Bridge Resort and Marina

2.5 star property
8.6 out of 10, Excellent, (239)
"price - clean and newly renovated boats - nice staff - easy check in/out."
Old Wooden Bridge Resort and Marina
Deer Run Bed & Breakfast
Outdoor pool, sun loungers

Deer Run Bed & Breakfast

2.5 star property
8.0 out of 10, Very Good, (1)
"Loved it. Beautiful property."
Deer Run Bed & Breakfast
Tropical Caribbean Paradise with pool!
Pool

Tropical Caribbean Paradise with pool!

9.2 out of 10, Wonderful, (88)
"RV was very clean and comfortable. Perfect spot to end each day. The RV park was very quiet at night. Location was excellent close to both northern and southern keys. Would definitely recommend. "
Tropical Caribbean Paradise with pool!
Big Pine Key Unique Direct Ocean Access with 10K lbs private dock boat lift
Sun loungers, beach towels

Big Pine Key Unique Direct Ocean Access with 10K lbs private dock boat lift

9.4 out of 10, Exceptional, (8)
"We had a wonderful holiday vacation. Thank you Kelly and Walter for sharing your vacation rental with our family."
Big Pine Key Unique Direct Ocean Access with 10K lbs private dock boat lift
Amazing Pool & Canal Ground Level Home, Ocean access
Outdoor pool, a heated pool

Amazing Pool & Canal Ground Level Home, Ocean access

10.0 out of 10, Exceptional, (16)
"Property was fantastic, instant communication with the owner. I would highly recommend and will stay here again on our next trip to the keys. 5 stars all the way."
Amazing Pool & Canal Ground Level Home, Ocean access
🐠 HEATED SWIM SPA / OPEN WATER VIEWS / BOAT DOCK / LUXURIOUS / BUILT IN 2023🐬
Outdoor spa tub

🐠 HEATED SWIM SPA / OPEN WATER VIEWS / BOAT DOCK / LUXURIOUS / BUILT IN 2023🐬

10.0 out of 10, Exceptional, (4)
"The house is amazing. The rooftop views are second to none and the boating access is some of the best in the keys. And the fishing is amazing restaurants within walking distance"
🐠 HEATED SWIM SPA / OPEN WATER VIEWS / BOAT DOCK / LUXURIOUS / BUILT IN 2023🐬
Keys To The Kingdom! Private Oceanfront Retreat with Beach and Pool
Interior

Keys To The Kingdom! Private Oceanfront Retreat with Beach and Pool

10.0 out of 10, Exceptional, (2)
"This property is making it to the top of our favorites! The view is the best. Very distracting when needing to work. The property was clean, everything worked, had everything we needed, the neighborhood was nice and quiet. Took full advantage of the kayaks and loved all the sea life we encountered. Lots of young sharks, sawfish, turtles, rays, sea slugs, crabs etc up in the shallows . Snorkeling right in front of the house, even tried our hand at lobster tickling. We brought jet skis and...
Keys To The Kingdom! Private Oceanfront Retreat with Beach and Pool
Banana Republics - Located in Paradise
Beach nearby

Banana Republics - Located in Paradise

10.0 out of 10, Exceptional, (1)
"We loved the property! The area was wonderful to walk the dog and see the key deer. The owner was very helpful with all our needs. We would absolutely stay there again!"
Banana Republics - Located in Paradise
Secluded Tropical Retreat: 60' Dock, Large Pool, World-Class Fishing & Lobster
Fridge, microwave, oven, stovetop

Secluded Tropical Retreat: 60' Dock, Large Pool, World-Class Fishing & Lobster

10.0 out of 10, Exceptional, (1)
"This property exceeded our expectations. The layout allowed for privacy with the upstairs loft bedroom/bathroom combination. The screened in wrap around porch was a dream. We could grill, eat and relax out there without any bugs. It also allowed us to have the screen doors shut and get a beautiful breeze into the house off the water. When the private gate opens you truly feel like you are on your own island. The saltwater pool is heated and the landscaping gave amazing privacy. The location was...
Secluded Tropical Retreat: 60' Dock, Large Pool, World-Class Fishing & Lobster
Big Pine Key Waterfront Home: Boating, Sunrises, Sunsets; Relax in Paradise!
Sun loungers, beach towels

Big Pine Key Waterfront Home: Boating, Sunrises, Sunsets; Relax in Paradise!

10.0 out of 10, Exceptional, (32)
"We thoroughly enjoyed our stay in this nicely updated and well appointed home. Views of the water on the beautiful deck are spectacular. A great spot to enjoy the sunrise."
Big Pine Key Waterfront Home: Boating, Sunrises, Sunsets; Relax in Paradise!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Looking for a spa hotel in Big Pine Key?
Treat yourself to some time in a luxurious spa hotel and you won’t regret it. Check out the beaches in Big Pine Key - worth a picture or two! Be sure to enjoy activities like kayaking and snorkeling during your stay. Hotels with spas are the perfect way to break away from your routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Big Pine Key?
Among Expedia’s 88 accommodation options in Big Pine Key, there are 2 spa hotels.
What's there to see and do in Big Pine Key?
Enjoy all that Big Pine Key has to offer and visit Calusa Beach, Bahia Honda State Park, and Florida Keys Beaches. If you have extra time while you’re in the area, you might want to see Big Pine Key Flea Market and Cook Island.
What is a Big Pine Key spa hotel?
Spa hotels in Big Pine Key provide lodging and have an on-site spa offering services such as massages and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.