Find 4 Star Hotels in Upstate South Carolina, SC from SAR 419

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Upstate South Carolina 4 Star Hotels

Tonight
27 Jul - 28 Jul
Tomorrow
28 Jul - 29 Jul
Next weekend
1 Aug - 3 Aug
In two weeks
8 Aug - 10 Aug

Compare Upstate South Carolina 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

The Shepherd Hotel Downtown Clemson
Superior Room, 2 Queen Beds | 1 bedroom, in-room safe, blackout drapes, soundproofing

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (643)
"Wonderful place to stay on Clemson’s campus."
The price is SAR 709
SAR 787 total
includes taxes & fees
3 Aug - 4 Aug
The Shepherd Hotel Downtown Clemson
Grand Bohemian Lodge Greenville, Autograph Collection
Lobby

Grand Bohemian Lodge Greenville, Autograph Collection

4.0 star property
9.6 out of 10, Exceptional, (361)
"We had a wonderful 3 night stay in Greenville, and the location of the Grand Bohemian made it a perfect location for walking and biking on the path and enjoying the lover river flowing through the middle of the city. We loved every moment of our stay, and we will definitely be back soon!"
The price is SAR 908
SAR 999 total
includes taxes & fees
17 Aug - 18 Aug
Grand Bohemian Lodge Greenville, Autograph Collection
The Westin Poinsett Greenville
Meeting facility

The Westin Poinsett Greenville

4.0 star property
9.2 out of 10, Wonderful, (1007)
"Every person from front desk to wait staff were personable and friendly. Wonderful stay. "
The price is SAR 672
SAR 739 total
includes taxes & fees
3 Aug - 4 Aug
The Westin Poinsett Greenville
Mint House Greenville - Downtown
Apartment, 2 Bedrooms | 3 bedrooms, laptop workspace, iron/ironing board, free WiFi

Mint House Greenville - Downtown

4.0 star property
9.2 out of 10, Wonderful, (704)
"Will definitely stay again!"
The price is SAR 419
SAR 473 total
includes taxes & fees
17 Aug - 18 Aug
Mint House Greenville - Downtown
Hotel Hartness
Restaurant

Hotel Hartness

4.0 star property
9.8 out of 10, Exceptional, (567)
"Beautiful property and attentive staff. "
The price is SAR 681
SAR 876 total
includes taxes & fees
31 Jul - 1 Aug
Hotel Hartness
Greenville Marriott
1 bedroom, premium bedding, down comforters, pillowtop beds

Greenville Marriott

4.0 star property
8.6 out of 10, Excellent, (582)
"The staff was excellent and the facility was user friendly"
The price is SAR 491
SAR 558 total
includes taxes & fees
3 Aug - 4 Aug
Greenville Marriott
The Abernathy of Clemson
Meeting facility

The Abernathy of Clemson

4.0 star property
9.6 out of 10, Exceptional, (532)
"Very nice staff, beautiful rooms"
The Abernathy of Clemson
Barsala At The American Spinning Mill Apartments
Apartment, 2 Bedrooms | Living area | 40-inch TV with digital channels

Barsala At The American Spinning Mill Apartments

4.0 star property
7.8 out of 10, Good, (34)
"Great access to bike trail. No working elevator and 3 flights of stairs with luggage is a challenge. "
Barsala At The American Spinning Mill Apartments
The Station by Compo Hotels
Trailside Wedge Cottage | Terrace/patio

The Station by Compo Hotels

4.0 star property
10.0 out of 10, Exceptional, (8)
"Beautiful rooms and surroundings. Less than 5 minutes from Furman university and really close to delightful and quirky travelers rest! Great place to stay!"
The price is SAR 673
SAR 1,049 total
includes taxes & fees
29 Jul - 30 Jul
The Station by Compo Hotels
Liberty Hall Bed and Breakfast
Restaurant

Liberty Hall Bed and Breakfast

4.0 star property
10.0 out of 10, Exceptional, (66)
"In town for a recent college visit. Great location in a stunning historic BNB. Breakfast was wonderful and customer service was exceptional. Would absolutely recommend staying here and plan to stay again."
The price is SAR 560
SAR 622 total
includes taxes & fees
10 Aug - 11 Aug
Liberty Hall Bed and Breakfast
Hotel Domestique
Bar (on property)

Hotel Domestique

4.0 star property
9.6 out of 10, Exceptional, (29)
"This place is a hidden gem. It is beautiful in every way. The staff is wonderful. The restaurant was incredible. Can’t wait to go back for a longer stay."
The price is SAR 1,572
SAR 1,729 total
includes taxes & fees
28 Jul - 29 Jul
Hotel Domestique
Southern Sunshine Retreat
42-inch flat-screen TV with digital channels

Southern Sunshine Retreat

4.0 star property
Southern Sunshine Retreat
Lake Hartwell Frank Howard Home Clemson
Signature House, 4 Bedrooms, Patio | Living room | 43-inch Smart TV with cable channels, TV, fireplace

Lake Hartwell Frank Howard Home Clemson

4.0 star property
The price is SAR 428
SAR 1,663 total
includes taxes & fees
4 Aug - 5 Aug
Lake Hartwell Frank Howard Home Clemson
Belvedere
Family House, 4 Bedrooms, Patio, Courtyard View | Terrace/patio

Belvedere

4.0 star property
8.0 out of 10, Very Good, (1)
"Bring everything. Including hangers for your clothes, salt and pepper, etc. it is like staying at a place that has one purpose, to rent out. Beds are uncomfortable. Nice big closets with one wire hanger. Why??? "
Belvedere
228 Lakeland
Dock

228 Lakeland

4.0 star property
228 Lakeland
140 Catlin Circle
House | Exterior

140 Catlin Circle

4.0 star property
140 Catlin Circle
Randall St , 202/204
House (202 / 204 Randall St Full Duplex) | Private kitchen | Coffee/tea maker, highchair, blender, cookware/dishes/utensils

Randall St , 202/204

4.0 star property
Randall St , 202/204
34 Allen St
Stovetop, dishwasher, coffee/tea maker, toaster

34 Allen St

4.0 star property
34 Allen St
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina
Greenville - Spartanburg showing a sunset, tranquil scenes and mountains
Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism

Top Upstate South Carolina Hotel Reviews

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

10/10 Excellent
"The property was easy walking distance to shopping and great food. Located right at the falls. Building is beautiful, clean, well maintained. Valet parking was 35$/ day. Parking a short walking distance away, but in an open parking lot is 5$ per day"
Charles 2-night trip
Posted 9 days ago
Grand Bohemian Lodge Greenville, Autograph Collection

Frequently asked questions

What are the best 4-star hotels in Upstate South Carolina?
Stay at Greenville Marriott and get ready for upscale comfort and plenty of handy amenities. This 4-star hotel in Greer, Upstate South Carolina, is highly recommended by Expedia guests.
How much does it cost to stay in a 4-star hotel in Upstate South Carolina?
Expedia can help you quickly locate the perfect 4-star hotel for your getaway in Upstate South Carolina. Use our handy filter tool to tailor your search by things like amenities, budget and property star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price from SAR 419

What's the difference between 5-star and 4-star hotels in Upstate South Carolina?
Offering a friendly guest experience and upmarket décor, 4-star hotels are a wonderful option for your Upstate South Carolina trip. These kinds of accommodations generally come with loads of handy amenities that make it simple to kick back and relax — think large beds, bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. Full-service health clubs, premium toiletries and fine dining are typically featured at these deluxe retreats.