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Check availability on Syracuse Luxury Hotels

Tonight
8 Dec - 9 Dec
Tomorrow
9 Dec - 10 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

Top Syracuse Luxury Hotels

Sports facility
Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia

5.0 star property
Syracuse
9.6 out of 10, Exceptional, (94)
"This was such a wonderful stay! Spotless beautiful property with friendly staff and delicious breakfast!!! Very impressed!"
United States
Jeffrey
The price is SAR 2,548
SAR 2,847 total
includes taxes & fees
1 Jan - 2 January 2026
Wellness & Spa Hotel Principe di Fitalia
Classic Double Room, Partial Sea View | View from room
Charme Hotel Henry's House

Charme Hotel Henry's House

4.0 star property
Ortigia
9.6 out of 10, Exceptional, (322)
"Great location. Very friendly and helpful staff. Nice breakfast."
United States
Alan
The price is SAR 980
SAR 1,122 total
includes taxes & fees
27 Dec - 28 Dec
Charme Hotel Henry's House
Exterior
Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection

5.0 star property
Ortigia
9.4 out of 10, Exceptional, (250)
"Great location and very friendly staff"
United States
James
The price is SAR 823
SAR 949 total
includes taxes & fees
6 Jan - 7 January 2026
Ortea Palace Hotel, Sicily, Autograph Collection
Exterior
Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa

5.0 star property
Syracuse
9.2 out of 10, Wonderful, (209)
"We experienced outstanding service from all of the staff, the breakfast buffet was lovely, lots of options and all homemade. We had a fantastic dinner in the restaurant one evening, which we booked ahead of our trip. "
United Kingdom
David
Dimora Caiammari Luxury Hotel & Spa
Reception
Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection

4.0 star property
Ortigia
9.4 out of 10, Exceptional, (659)
"Great hotel"
United States
Caterina
The price is SAR 805
SAR 930 total
includes taxes & fees
19 Dec - 20 Dec
Palazzo Artemide - VRetreats, SLH Collection
Aerial view
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

5.0 star property
Ortigia
9.0 out of 10, Wonderful, (570)
"Great stay!"
United States
Liza
The price is SAR 725
SAR 842 total
includes taxes & fees
7 Jan - 8 January 2026
Grand Hotel Ortigia Siracusa
Front of property - evening/night
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

4.0 star property
Ortigia
9.6 out of 10, Exceptional, (905)
"The breakfast was delicious, the staff impeccable and the room delightful. All in all an excellent stay which I would wholeheartedly recommend. "
United Kingdom
Sarah
Algila' Ortigia Charme Hotel
Pool
UNA HOTELS One Siracusa

UNA HOTELS One Siracusa

4.0 star property
Grottasanta
8.6 out of 10, Excellent, (540)
"Very nice hotel, nice sized rooms, great staff that was very helpful."
United States
Mark
The price is SAR 512
SAR 584 total
includes taxes & fees
11 Dec - 12 Dec
UNA HOTELS One Siracusa
Terrace/patio
Caportigia Boutique Hotel

Caportigia Boutique Hotel

5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (256)
"Fine quality hotel with exceptional service. "
United States
Peter
The price is SAR 452
SAR 541 total
includes taxes & fees
14 Dec - 15 Dec
Caportigia Boutique Hotel
Seasonal outdoor pool
Grand Hotel Villa Politi

Grand Hotel Villa Politi

4.0 star property
Grottasanta
8.6 out of 10, Excellent, (941)
"Wonderful hotel, nice area and great buffet breakfast"
United States
paula
The price is SAR 373
SAR 425 total
includes taxes & fees
9 Dec - 10 Dec
Grand Hotel Villa Politi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Syracuse Hotel Reviews

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

10/10 Excellent
"Great location. Great service. Enjoy Ortigia!"
Roger 7-night trip
Posted 10 days ago
Algila' Ortigia Charme Hotel

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Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Syracuse?
Travel to Fontanarossa Airport (CTA) Airport or Vincenzo Magliocco Airport (CIY) Airport, and then treat yourself to a stay at one of 5 Syracuse luxury hotels. While you're visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best high-end place to stay in Syracuse?
Grand Hotel Des Ètrangers - The Leading Hotels of the World is a luxury hotel with a full-service spa and a seasonal outdoor pool, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Grand Hotel Ortigia Siracusa and Wellness & Spa Hotel Principe di Fitalia are other upscale choices for your vacation.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia's 5 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 78°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for Syracuse is 26 inches.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia, and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Porto Piccolo.
How can I get around Syracuse?
It's easier to get around town in style when you know your options. To explore the surrounding area, ride one of the trains from Syracuse Station or Targia Station.