Lodging Image

Find hotels in Southeast Missouri, MO from SAR 233

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Southeast Missouri hotels

1. Shepherd Mountain Inn

Shepherd Mountain Inn
2.5 star property
Ironton
9.2 out of 10, Wonderful, (337 reviews)
"Clean room, wifi easy to connect to, parking right in front."
United States
Jonathan
The price is SAR 463
SAR 505 total
includes taxes & fees
9 Nov - 10 Nov
Shepherd Mountain Inn

2. Madison Inn Lodge

Madison Inn Lodge
2.5 star property
Fredericktown
7.6 out of 10, Good, (314 reviews)
"Nice and clean friendly staff"
United States
Bawan
The price is SAR 327
SAR 357 total
includes taxes & fees
4 Nov - 5 Nov
Madison Inn Lodge

3. Hampton Inn & Suites By Hilton Festus

Hampton Inn & Suites By Hilton Festus
Festus
9.4 out of 10, Exceptional, (22 reviews)
"This was a wonderful hotel and had a wonderful stay. Room was clean and staff was wonderful."
United States
Misty
The price is SAR 428
SAR 489 total
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn & Suites By Hilton Festus

4. Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG
2.5 star property
Farmington
8.6 out of 10, Excellent, (444 reviews)
"We stayed one night and it was great! Breakfast was delicious."
United States
January
The price is SAR 428
SAR 495 total
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Express & Suites Farmington by IHG

5. Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
Farmington
8.0 out of 10, Very good, (1,005 reviews)
"Our room was spacious, clean and the bed was super comfortable!"
Canada
Kim
The price is SAR 204
SAR 233 total
includes taxes & fees
9 Nov - 10 Nov
Baymont Inn and Suites by Wyndham Farmington, MO

6. Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
2.0 star property
Farmington
8.0 out of 10, Very good, (690 reviews)
"Clean nice staff are great"
United States
Marisa
The price is SAR 223
SAR 255 total
includes taxes & fees
15 Nov - 16 Nov
Super 8 by Wyndham Farmington

7. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,002 reviews)
"Clean room affordable and great breakfast I would definitely go back!"
United States
Lyn
The price is SAR 300
SAR 317 total
includes taxes & fees
8 Nov - 9 Nov
Drury Inn & Suites Jackson MO

8. Fort Davidson Hotel

Fort Davidson Hotel
2.5 star property
Ironton
9.2 out of 10, Wonderful, (190 reviews)
"Clean rooms , nice pool."
United States
richard
The price is SAR 469
SAR 512 total
includes taxes & fees
5 Nov - 6 Nov
Fort Davidson Hotel

9. Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
2.5 star property
Farmington
8.8 out of 10, Excellent, (700 reviews)
"Tucked away gem."
United States
christopher
The price is SAR 380
SAR 434 total
includes taxes & fees
19 Nov - 20 Nov
Crown Pointe Lodge, BW Signature Collection

10. Hampton Inn Farmington

Hampton Inn Farmington
2.5 star property
Farmington
8.8 out of 10, Excellent, (582 reviews)
"The staff were so friendly & housekeeping came in each day to take care of our room. The breakfast was one of the best we have had. We had a great stay. Thank you to the staff!"
United States
Charlie
The price is SAR 373
SAR 427 total
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn Farmington

11. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.4 out of 10, Exceptional, (117 reviews)
"Awesome hotel and staff was first rate, everything was fantastic. If you are in the area, stay at this hotel and eat in!!"
United States
Jan
The price is SAR 395
SAR 430 total
includes taxes & fees
4 Nov - 5 Nov
EC Reed's Mercantile and Hotel

12. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (118 reviews)
"Friendly staff, great breakfast, nice amenities"
United States
Roslyn
The price is SAR 379
SAR 431 total
includes taxes & fees
15 Nov - 16 Nov
Fairfield Inn & Suites by Marriott Sikeston

13. The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (700 reviews)
"Great property"
United States
John
The price is SAR 403
SAR 455 total
includes taxes & fees
9 Nov - 10 Nov
The Riverview

14. Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (644 reviews)
"Excellent stay , couldn't believe the property was 10 years old , it looks like it was just built , great place , highly recommend ."
United States
allan p.
The price is SAR 379
SAR 434 total
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Express & Suites Perryville by IHG

15. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,008 reviews)
"Great stay! Hot tub was enjoyable and the staff was super friendly!"
United States
Chris
The price is SAR 375
SAR 423 total
includes taxes & fees
8 Nov - 9 Nov
Drury Plaza Hotel Cape Girardeau Conference Center

16. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (29 reviews)
"I liked the lobby, bar and breakfast areas. The full breakfast buffet was awesome. Super nice room with kitchenette. Staff were great."
United States
Mark
The price is SAR 409
SAR 465 total
includes taxes & fees
12 Nov - 13 Nov
TownePlace Suites by Marriott Sikeston

17. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (1,002 reviews)
"Clean, great food, excellent staff."
United States
Dean
The price is SAR 338
SAR 382 total
includes taxes & fees
15 Nov - 16 Nov
Drury Inn & Suites Poplar Bluff

18. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (975 reviews)
"Everything was great- breakfast, cleanliness, price— will stay there again"
United States
ELAINE
The price is SAR 364
SAR 411 total
includes taxes & fees
15 Nov - 16 Nov
Fairfield Inn & Suites by Marriott Poplar Bluff

19. Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
2.0 star property
Perryville
8.6 out of 10, Excellent, (1,004 reviews)
"Nice room, friendly staff."
United States
Matthew
The price is SAR 258
SAR 296 total
includes taxes & fees
15 Nov - 16 Nov
Super 8 by Wyndham Perryville

20. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (1,003 reviews)
"Everything was great about the stay!"
United States
Denise
The price is SAR 341
SAR 382 total
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn Poplar Bluff
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Vacation Rentals in Southeast Missouri

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southeast Missouri attractions

Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.

A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.
Photo by Bill Dillard
Open Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

More cheap stays in Southeast Missouri

Hotels in Southeast Missouri with star-rating

Find out more about Southeast Missouri

Top reasons to visit Southeast Missouri

  • Outdoor Adventures: Southeast Missouri is perfect for outdoor enthusiasts, featuring urban parks, scenic state parks, and recreational activities.
  • Charming Towns: Explore friendly towns like Cape Girardeau and Sikeston, offering local charm and hospitality.
  • Mississippi River Views: Enjoy leisurely strolls along the picturesque Mississippi River, taking in the scenic beauty.
  • Family-Friendly Attractions: The region boasts a variety of attractions suitable for families, making it a fun vacation spot.
  • Diverse Accommodations: From cozy lodges to modern hotels, Southeast Missouri offers a range of lodging options for every traveler.

Find great hotels near Southeast Missouri

In Southeast Missouri, you'll discover a diverse selection of accommodations, from cozy lodges to well-appointed hotels, catering to both business and leisure travelers. Whether you seek family-friendly options, an adventure-packed getaway, or proximity to local attractions, this region offers a variety of choices. Explore the best hotels, read reviews, and find the perfect place to unwind during your visit to this charming corner of the United States.

  • Madison Inn Lodge: A cozy motel that caters to both business travelers and pet enthusiasts. Situated 25.7km from Southeast Missouri, Madison Inn Lodge offers a welcoming atmosphere where pets are permitted, making it an ideal choice for those traveling with furry companions. The property features essential amenities suitable for business stays, ensuring a comfortable experience for all guests. With a pet-friendly policy that includes some restrictions and a waiver for service animals, this lodge strikes a balance between convenience and comfort.
  • Shepherd Mountain Inn: Located 33.8km from Southeast Missouri, Shepherd Mountain Inn is a classic hotel designed for the business traveler. With its straightforward amenities and comfortable accommodations, this property provides a functional base for those visiting the area for work. Guests appreciate the inn's professional environment, which promotes productivity and relaxation after a busy day. Its proximity to local businesses and attractions makes it a pragmatic choice for anyone looking to blend work with leisure.
  • Alpaca Farm Stay: Nestled just 12.9km from Southeast Missouri, Alpaca Farm Stay offers a unique experience for adventure seekers and families. This lodge features various outdoor activities, including motorboating, hiking, kayaking, fishing, and birdwatching, making it perfect for those who love the great outdoors. Families will enjoy amenities like a shared playground, while couples can take advantage of special romance packages. With picturesque views of the lake and mountains, this property invites guests to unwind and create lasting memories in a serene setting.

Where to stay near Southeast Missouri

For an unforgettable vacation, Southeast Missouri offers a perfect blend of scenic retreats and family-friendly adventures. Explore the charming towns like Cape Girardeau and Sikeston, where friendly locals welcome you. Enjoy leisurely strolls along the scenic Mississippi River or immerse yourself in outdoor activities in the lush parks. With its convenient location and vibrant atmosphere, Southeast Missouri is an ideal destination for families seeking recreation and relaxation, making it a memorable getaway.

  • Annapolis: Nestled 22.5km from Southeast Missouri, Annapolis is a charming city that attracts visitors year-round, with peak arrivals during June to July and September. Known for its stunning outdoor scenery and adventurous spirit, Annapolis offers a range of recreational activities, including access to a national state park and beautiful riverside parks. Whether you're hiking, picnicking, or simply enjoying the fresh air, Annapolis promises an invigorating experience for nature lovers and adventure seekers alike.
  • Central Fredericktown: Located just 16.1km from Southeast Missouri, Central Fredericktown is a delightful village perfect for family adventures and city-themed exploration. With visitor numbers peaking from June to August, this vibrant area features a variety of attractions, including a shopping mall and educational centers. Families will enjoy the local history museum and parks, making it an excellent destination for learning and leisure. Central Fredericktown blends small-town charm with engaging activities for all ages.
  • Des Arc: A mere 17.7km away from Southeast Missouri, Des Arc is a lively city known for its seasonal tourism, with visitors flocking in from June to August. This city offers a wealth of outdoor activities, including access to a water park and national state parks, making it ideal for those seeking adventure and stunning natural scenery. With its picturesque lakes and rivers, Des Arc invites you to explore its recreational areas while unwinding in a serene setting, ensuring a memorable getaway.

Things to do near Southeast Missouri

Southeast Missouri offers a wealth of outdoor adventures and scenic beauty, making it an ideal vacation spot. Visitors can enjoy a variety of activities including campus tours, recreational areas, sports tournaments, brewery tours, and educational experiences. The region is also home to an arena entertainment facility, ensuring a fun-filled trip for all. Whether you're looking for relaxation or excitement, Southeast Missouri has something for everyone.

Shopping

For a unique shopping experience in Southeast Missouri, visit Red's Flea Market, located 41.8km away, offering a vibrant atmosphere filled with local treasures. Alternatively, head to Farmington Mineral Area Shopping Center, 48.3km away, where you'll find a variety of shops perfect for family fun and entertainment.

Recreation

At Crane Lake Recreation Area, enjoy serene nature trails and peaceful surroundings that promote relaxation. Arcadia Valley Golf Club offers invigorating outdoor experiences with scenic views while you play golf. Silver Mine Recreation Area provides a tranquil environment perfect for unwinding amidst beautiful landscapes.

Adventure

Shepherd Mountain Bike Park and Hiking Trails, located 33.8km from Southeast Missouri, offers thrilling mountain biking and scenic hiking trails. Experience the stunning landscapes, immerse yourself in nature, and enjoy the exhilarating outdoor adventure vibes that this destination has to offer.

Nightlife

Southeast Missouri offers a vibrant nightlife scene. Enjoy live music at The Blue Note in Columbia or dance the night away at The Loft in Cape Girardeau. For a laid-back vibe, grab drinks at The Tap Room, where locals gather for good conversation and a friendly atmosphere.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Southeast Missouri

To save money on your trip to Southeast Missouri, consider visiting between November and January when prices are lower. Tuesdays offer the best hotel rates, while Saturdays are the most expensive. Use Expedia to refine your hotel search by budget and location, and try combining your hotel, flights, and activities for better deals. Look for hotel packages and compare room rates to find the best bargains. Additionally, explore free local attractions and utilize public transport to keep your expenses down.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Southeast Missouri are November to January, where the prices are slightly lower. This is in comparison to April, June and August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Southeast Missouri is Tuesday. The most expensive day to stay around Southeast Missouri is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia's search tool to refine your preferences, such as budget, desired location, and the type of hotel you prefer. To find the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel reservations in Southeast Missouri with your flights and activities through an Expedia package.

Find the best attractions near Southeast Missouri

For an exciting vacation in Southeast Missouri, outdoor enthusiasts will find plenty to explore, from urban parks to scenic state parks and historic civic buildings. Perfect for family experiences, the area offers a variety of attractions, including nearby sites and the Southeast Missouri State University. Whether you're seeking adventure or simply enjoying nature's beauty, Southeast Missouri has something for everyone.

  • Walnut Hollow Lake: Located 20.9km from Southeast Missouri, Walnut Hollow Lake offers a romantic atmosphere with beautiful beaches and scenic views, perfect for outdoor enthusiasts looking to relax by the water.
  • K Bridge Recreation Area: Situated 27.4km away, this urban park is ideal for families, featuring expansive outdoor spaces where city vibes meet nature, making it a great spot for picnics and leisurely strolls.
  • Millstream Gardens Conservation Area: Just 24.1km from Southeast Missouri, this preserve is known for its friendly atmosphere and adventurous trails, perfect for families seeking relaxation alongside historical insights.

Best time to go to Southeast Missouri

The best time to visit Southeast Missouri is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January34.9°F (1.6°C)Light RainMostly SunnySlightly LowSlightly Low
February38.1°F (3.4000000000000004°C)Light RainMostly SunnySlightly LowAverage
March48.0°F (8.9°C)Light RainMostly SunnyAverageAverage
April57.6°F (14.2°C)Light RainMostly SunnyAverageSlightly High
May67.3°F (19.6°C)Light RainMostly SunnyAverageAverage
June76.5°F (24.700000000000003°C)Light RainMostly SunnySlightly HighSlightly High
July79.2°F (26.200000000000003°C)Light RainMostly SunnySlightly HighAverage
August77.2°F (25.1°C)Light RainMostly SunnySlightly HighSlightly High
September71.6°F (22.0°C)Light RainMostly SunnyAverageAverage
October59.9°F (15.5°C)Light RainMostly SunnyAverageAverage
November47.5°F (8.6°C)Light RainMostly SunnyAverageSlightly Low
December39.4°F (4.1000000000000005°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Southeast Missouri

For your visit to Southeast Missouri, you can fly into several nearby airports. St. Louis Lambert International Airport (STL) is 154.5km away, with hotels like The Ritz-Carlton, St. Louis, a 5-star hotel 11.3km from the airport, and Ameristar Casino Resort and Spa, also 11.3km away. Fort Leonard Wood Regional Airport (TBN) is another option, 154.5km away, featuring Z Loft Extended Stay Hotel, just 9.7km from the airport. Finally, Paducah Barkley Regional Airport (PAH) is 152.9km away, with The Respite Bed and Breakfast, a 4.5-star option 14.5km from the airport. Each airport provides convenient access to comfortable accommodations.