Find Boutique Hotels in South Carolina Midlands, SC
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Recommended hotels in South Carolina Midlands
Tru By Hilton Santee
Santee
9.2 out of 10, Wonderful, (631)
"Nice place to stay"
Tanya
The price is SAR 360
SAR 400 total
includes taxes & fees
4 Jan - 5 January 2026
Holiday Inn Express & Suites Latta by IHG
Latta
9.4 out of 10, Exceptional, (532)
"Clean and beautiful, very friendly staff "
claudia
The price is SAR 443
SAR 483 total
includes taxes & fees
4 Jan - 5 January 2026
Baymont by Wyndham Santee
Santee
8.0 out of 10, Very Good, (1410)
"The best stay"
Terez
The price is SAR 300
SAR 333 total
includes taxes & fees
14 Dec - 15 Dec
Howard Johnson by Wyndham Florence
Florence
8.6 out of 10, Excellent, (2480)
"I nice place to stay, very quiet, good breakfast, nice staff, spotless room. "
Timothy
The price is SAR 233
SAR 261 total
includes taxes & fees
17 Dec - 18 Dec
Comfort Inn & Suites Florence Center Area
Florence
9.2 out of 10, Wonderful, (1162)
"Enjoyed our stay there. "
Cathy
The price is SAR 380
SAR 425 total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn & Suites Lexington Columbia
Lexington
9.8 out of 10, Exceptional, (589)
"Clean and comfortable room, friendly staff, great location."
Allison
The price is SAR 387
SAR 430 total
includes taxes & fees
4 Jan - 5 January 2026
Fairfield Inn & Suites by Marriott Santee
Santee
9.8 out of 10, Exceptional, (1000)
"Clean, friendly staff, new, good value"
Robert
The price is SAR 454
SAR 504 total
includes taxes & fees
21 Dec - 22 Dec
Lexington Expo Hotel by IHG
Lexington
9.2 out of 10, Wonderful, (1001)
"Room was great staff was great"
Stephen
The price is SAR 360
SAR 400 total
includes taxes & fees
19 Dec - 20 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top South Carolina Midlands Hotel Reviews
Graduate by Hilton Columbia SC
10/10 Excellent
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Hotels near popular South Carolina Midlands Attractions
- Hotels near Fort Jackson
- Hotels near University of South Carolina
- Hotels near Carowinds Theme Park
- Hotels near Riverbanks Zoo and Garden
- Hotels near Colonial Life Arena
- Hotels near Williams Brice Stadium
- Hotels near Florence Civic Center
- Hotels near Township Auditorium
- Hotels near Darlington Raceway
- Hotels near Columbia Metropolitan Convention Center
South Carolina Midlands Hotels by Star Rating
Explore more hotels
- Tru By Hilton Columbia Greystone
- Park Inn by Radisson Florence, SC
- La Quinta Inn by Wyndham Columbia NE/Fort Jackson
- Comfort Inn & Suites Florence Center Area
- Springhill Suites by Marriott Columbia near Fort Jackson
- Courtyard by Marriott Columbia Northeast/Fort Jackson Area
- Hyatt Place Columbia/Harbison
- Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG
- Country Inn & Suites by Radisson, Columbia, SC
- Courtyard by Marriott Columbia Downtown at USC
- Comfort Suites Columbia at Harbison
- Marriott Columbia
- Hyatt Place Columbia/Downtown/The Vista
- Tru By Hilton Santee
- Hyatt Place Florence Downtown
- Holiday Inn Columbia - Downtown by IHG
- Hampton Inn Columbia-I-26 Airport
- Baymont by Wyndham Santee
- Clarion Pointe Rock Hill Near University
- Spark by Hilton Rock Hill