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Go beyond your typical stay in Santa Cruz

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Check prices for these dates

Tonight
13 Nov - 14 Nov
Tomorrow
14 Nov - 15 Nov
This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

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Our top choices for Santa Cruz hotels

The exterior of the LQ Hotel La Quinta with its modern glass facade and a signboard displaying the hotel name.

1. La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin
3.5 star property
San Diego
9.0 out of 10, Wonderful, (1,002 reviews)
"Location, service is wonderful"
United States
Rene
The price is SAR 286
SAR 286 total
5 Dec - 6 Dec
La Quinta by Wyndham Medellin
A modern interior with a circular window, a seating area with a cushioned bench, and a small table.

2. Garden Hotel by Urbit

Garden Hotel by Urbit
3.0 star property
Laureles
9.2 out of 10, Wonderful, (109 reviews)
"Great place to stay!"
United States
Elio Rafael
The price is SAR 192
SAR 192 total
25 Nov - 26 Nov
Garden Hotel by Urbit
A modern building with large glass windows and a neon sign.

3. ibis Medellin

ibis Medellin
3.0 star property
El Poblado
8.8 out of 10, Excellent, (1,000 reviews)
"Great location and staff were really friendly"
United States
Yuliana
The price is SAR 211
SAR 211 total
29 Nov - 30 Nov
ibis Medellin
A hotel room with a balcony overlooking a cityscape, a bed with patterned pillows, and a painting of a flower on the wall.

4. Hotel Dorado La 70

Hotel Dorado La 70
4.0 star property
Laureles
9.0 out of 10, Wonderful, (1,916 reviews)
"Very good place to stay."
United States
Gregson
The price is SAR 258
SAR 258 total
15 Nov - 16 Nov
Hotel Dorado La 70
A modern hotel room with a large bed, a sitting area with a table and chairs, a large window with a view of buildings, and a hot tub.

5. Eutopiq Hotel

Eutopiq Hotel
3.5 star property
Laureles
9.4 out of 10, Exceptional, (365 reviews)
"Breakfasts, clean room, excellent customer service"
United States
Ramiro
The price is SAR 218
SAR 218 total
30 Nov - 1 Dec
Eutopiq Hotel
An outdoor patio area with wicker furniture, a brick floor, and a view of a building with large windows and indoor lighting.

6. Fairfield by Marriott Medellin Sabaneta

Fairfield by Marriott Medellin Sabaneta
3.5 star property
Sabaneta
9.4 out of 10, Exceptional, (291 reviews)
"It was a really good stay. Thought it was inconvenient not to be able to charge expenses to the room like in most hotels, but it was nice regardless. The staff in general were very nice, Oscar especially was very attentive and helpful."
United States
Estefania
The price is SAR 323
SAR 323 total
11 Dec - 12 Dec
Fairfield by Marriott Medellin Sabaneta
A dining table with breakfast items, a pool, and a building with a brick facade.

7. Hotel Dann Carlton Belfort Medellin

Hotel Dann Carlton Belfort Medellin
4.0 star property
El Poblado
8.8 out of 10, Excellent, (1,008 reviews)
"Very nice hotel !!!"
United States
jaime
The price is SAR 312
SAR 312 total
16 Nov - 17 Nov
Hotel Dann Carlton Belfort Medellin
A hotel lobby with a reception desk, seating area, and a large chandelier.

8. Hotel Egina Medellín

Hotel Egina Medellín
3.0 star property
Laureles - Estadio
8.4 out of 10, Very good, (1,000 reviews)
"Great service, friendly people"
United States
David
The price is SAR 232
SAR 232 total
16 Nov - 17 Nov
Hotel Egina Medellín
A modern bathroom with a large mirror, two sinks, a shower, and toiletries.

9. Novotel Medellín El Tesoro

Novotel Medellín El Tesoro
4.5 star property
El Poblado
9.4 out of 10, Exceptional, (1,483 reviews)
"Great stay!"
United States
Haydee
The price is SAR 476
SAR 476 total
27 Nov - 28 Nov
Novotel Medellín El Tesoro
A modern kitchen with a central island, bar area, and seating.

10. Loma, Medellin, a Tribute Portfolio Hotel

Loma, Medellin, a Tribute Portfolio Hotel
4.0 star property
El Poblado
9.4 out of 10, Exceptional, (468 reviews)
"Such a gem of a hotel reasonably priced food in the restaurant which was delicious. Free breakfast had many options. The gym was functional and decently equipped. The most important the place was spotless and the staff is A1"
United States
Ace Amari
The price is SAR 375
SAR 375 total
20 Nov - 21 Nov
Loma, Medellin, a Tribute Portfolio Hotel
A pathway leading to a building with a modern design, surrounded by lush greenery and trees.

11. Hotel centro logistico del norte

Hotel centro logistico del norte
2.0 star property
Bello
10.0 out of 10, Exceptional, (4 reviews)
"Excelente muy buena atención"
United States
Sergio
The price is SAR 56
SAR 103 total
14 Nov - 15 Nov
Hotel centro logistico del norte
A modern hotel room with a large bed, bedside tables, a desk, and a view of the city.

12. Moa Select

Moa Select
3.0 star property
Laureles
9.4 out of 10, Exceptional, (449 reviews)
"I stay here ones a month and it’s always a great experience. Great staff and clean bedrooms. Also very convenient location close to malls and restaurants"
United States
Jose
The price is SAR 182
SAR 182 total
14 Dec - 15 Dec
Moa Select
A buffet area with various food items, a clock on the wall, and a view of the city through large windows.

13. Hotel BH El Poblado

Hotel BH El Poblado
3.5 star property
El Poblado
9.2 out of 10, Wonderful, (1,001 reviews)
"Great Hotel"
United States
Francisco
The price is SAR 240
SAR 240 total
8 Dec - 9 Dec
Hotel BH El Poblado
A hotel room with a bed, desk, chair, TV, and a view of buildings.

14. Hotel Living 35 Suites by Growing Group

Hotel Living 35 Suites by Growing Group
4.0 star property
La América
9.6 out of 10, Exceptional, (257 reviews)
"Great safe and amazing place to stay! Breakfast was great!"
United States
Matthew
The price is SAR 197
SAR 197 total
16 Nov - 17 Nov
Hotel Living 35 Suites by Growing Group
A modern hotel building with a prominent sign reading "MIRAGE HOTEL".

15. Arame Hotel

Arame Hotel
3.0 star property
Envigado
9.2 out of 10, Wonderful, (231 reviews)
"I would stay there again without a doubt"
United States
David
The price is SAR 304
SAR 304 total
16 Nov - 17 Nov
Arame Hotel
A bedroom with a large bed, a chair, and a view through a glass door.

16. Isak Hotel & Golf Airport

Isak Hotel & Golf Airport
3.0 star property
Rionegro
9.4 out of 10, Exceptional, (788 reviews)
"GREAT LOCATION"
United States
Emilia
The price is SAR 293
SAR 293 total
4 Dec - 5 Dec
Isak Hotel & Golf Airport
A rooftop bar with tables and chairs, a bar counter, and a city view at night.

17. Indie Universe Creative Hotel

Indie Universe Creative Hotel
4.5 star property
Laureles
8.6 out of 10, Excellent, (225 reviews)
"Great place to stay"
United States
Sypoutha Michael
The price is SAR 166
SAR 166 total
16 Nov - 17 Nov
Indie Universe Creative Hotel
A modern bedroom with a bed, bedside table, chair, and a desk.

18. beminimal parques

beminimal parques
4.0 star property
Laureles - Estadio
9.4 out of 10, Exceptional, (287 reviews)
"It was a very convenient place for my stay. The entire staff was incredibly helpful, kind, and efficient. The hotel is in a great location, especially if you’re visiting Plaza Mayor. I would definitely stay here again."
United States
Andreina
The price is SAR 294
SAR 294 total
3 Dec - 4 Dec
beminimal parques
A modern lobby with a large sectional sofa, a minimalist design, and a ceiling with a grid pattern.

19. The Cut Hotel

The Cut Hotel
4.0 star property
El Poblado
9.4 out of 10, Exceptional, (132 reviews)
"Todo excelente"
United States
Yesenia
The price is SAR 167
SAR 167 total
2 Dec - 3 Dec
The Cut Hotel
A reception desk with a computer, potted plants, and a television screen.

20. Hotel Sauces Del Estadio

Hotel Sauces Del Estadio
3.0 star property
Laureles - Estadio
8.4 out of 10, Very good, (197 reviews)
"Absolutely love this hotel, incredible staff "
United States
luz
The price is SAR 165
SAR 165 total
16 Nov - 17 Nov
Hotel Sauces Del Estadio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

A modern building with a sign reading "FIREZE" and a visible address.
Firenze Lofts

Firenze Lofts

Firenze Lofts
La América

10/10 Excellent

The rooms were very accommodating and clean with a very comfortable bed and usable kitchenette.
United States
Alan
Reviewed April 9, 2025
Firenze Lofts

Frequently Asked Questions

What's the top vacation rental that Santa Cruz has to offer?

6 Bedrooms House near Tourist Spots with backyard, Bar, Jacuzzi and heated pool: This vacation home rental near Santa Cruz offers an outdoor pool, a patio, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 6 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You can relax into your vacation with a garden and a hot tub. See all vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

Where can I learn more about changing or cancelling my trip to Santa Cruz?

For additional details about picking new dates or cancelling your trip to Santa Cruz, head over to our customer service page.

What is staying in Santa Cruz like?

Visitors are sure to enjoy all that Santa Cruz has to offer. In Santa Cruz, there are 4 hotels and other accommodations to choose from. Find out more about Santa Cruz.

What are the top places to visit in Santa Cruz?

Places to visit in the wider area include Medellin Botanical Garden, Arvi Park, and Antioquia Museum. You'll also find Botero Plaza and Atanasio Giradot Stadium in the area. Check out what more to see and do in Expedia's Santa Cruz guide.

How can I get around Santa Cruz?

Head over to Andalucía MetroCable Station for metro transit.

What's the weather like in Santa Cruz?

The hottest months are usually August and July with an average temp of 66°F, while the coldest months are December and January with an average of 64°F. The rainiest months in Santa Cruz are May, April, October, and November, with each month seeing an average of 16 inches of rainfall.

Where is the best place to stay in Santa Cruz?

Located 6.2 mi (10 km) from the heart of Santa Cruz, Calle Flora Hotel by Jalo is a top choice for your stay based on our traveler data. Other good choices for your trip to the area are Heiss Hotel By Jalo and Hashtag 98 Hotel By Jalo. See all available top hotels, or vacation rentals in Santa Cruz.