Find Resorts & Hotels with Spas in Portsmouth, OH

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Check availability on Portsmouth Resorts & Hotels with Spas

Tonight
4 Dec - 5 Dec
Tomorrow
5 Dec - 6 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top Portsmouth Resorts & Hotels with Spas

No exact matches found, but these alternatives could be just right

Recommended hotels in Portsmouth

BBQ/picnic area
Quality Inn

Quality Inn

2.5 star property
Wheelersburg
8.2 out of 10, Very Good, (311)
"The breakfast was very good, there was a variety of items to enjoy. Our rooms were very clean, and check-in was very easy. The property is well taken care of and the staff is friendly."
United States
Susanne L.
The price is SAR 334
SAR 372 total
includes taxes & fees
4 Jan - 5 January 2026
Quality Inn
Lobby
Super 8 by Wyndham Portsmouth

Super 8 by Wyndham Portsmouth

2.0 star property
Portsmouth
7.0 out of 10, Good, (681)
"We loved it and returned each time we are back est."
United States
Saundra
The price is SAR 252
SAR 280 total
includes taxes & fees
4 Jan - 5 January 2026
Super 8 by Wyndham Portsmouth
Exterior
Holiday Inn Portsmouth Downtown by IHG

Holiday Inn Portsmouth Downtown by IHG

3.0 star property
Portsmouth
8.6 out of 10, Excellent, (461)
"Clean room, friendly staff. Love this hotel, i stay here every timeni visit family."
United States
Cyndi
The price is SAR 432
SAR 481 total
includes taxes & fees
4 Jan - 5 January 2026
Holiday Inn Portsmouth Downtown by IHG
Microwave, oven, stovetop
The Little Smokies Escape: Cozy 2 Bedroom Cabin+Private Hot Tub+Starlink WiFi

The Little Smokies Escape: Cozy 2 Bedroom Cabin+Private Hot Tub+Starlink WiFi

Blue Creek
10.0 out of 10, Exceptional, (5)
"Over all, a nice little get away "
United States
jonathan
The price is SAR 507
SAR 1,009 total
includes taxes & fees
18 Dec - 19 Dec
The Little Smokies Escape: Cozy 2 Bedroom Cabin+Private Hot Tub+Starlink WiFi
Free daily continental breakfast
Red Roof Inn Wheelersburg

Red Roof Inn Wheelersburg

2.0 star property
Wheelersburg
7.0 out of 10, Good, (291)
"was very nice"
United States
garrett
The price is SAR 338
SAR 376 total
includes taxes & fees
7 Dec - 8 Dec
Red Roof Inn Wheelersburg
Lobby sitting area
Royal Inn

Royal Inn

2.5 star property
Portsmouth
6.0 out of 10, (123)
"Staff was very friendly and courteous "
United States
Gary
The price is SAR 244
SAR 271 total
includes taxes & fees
7 Dec - 8 Dec
Royal Inn
Interior
Charming 2-bedroom house in wonderful Portsmouth with AC, WiFi

Charming 2-bedroom house in wonderful Portsmouth with AC, WiFi

Portsmouth
10.0 out of 10, Exceptional, (14)
"Place was very clean and well kept will definitely stay here again"
United States
eric
The price is SAR 488
SAR 1,022 total
includes taxes & fees
16 Dec - 17 Dec
Charming 2-bedroom house in wonderful Portsmouth with AC, WiFi
Fridge, microwave, oven, stovetop
Large Historic District Apartment with City View

Large Historic District Apartment with City View

Portsmouth
10.0 out of 10, Exceptional, (5)
"This apartment was super cute. It's within walking distance to the murals and restaurants and bars. Highly recommend!"
United States
Molly L.
The price is SAR 450
SAR 525 total
includes taxes & fees
7 Dec - 8 Dec
Large Historic District Apartment with City View
Fridge, microwave, oven, stovetop
Private Accomodations in Historic Boneyfiddle

Private Accomodations in Historic Boneyfiddle

Portsmouth
9.6 out of 10, Exceptional, (15)
"Good location, kitchen, unique interior, and much cheaper than the Holiday Inn."
United States
Joy T.
The price is SAR 450
SAR 525 total
includes taxes & fees
7 Dec - 8 Dec
Private Accomodations in Historic Boneyfiddle
Exterior detail
The Kitchie Kottage/ House

The Kitchie Kottage/ House

Portsmouth
9.8 out of 10, Exceptional, (15)
"Immaculate and cozy, the host Anthony helpful, congenial and dependable, I love this place; it has become an annual stay. Beds are very comfy, kitchen is well provisioned for cooking or hosting. Lovely inside and outside, I highly recommend The Kitchie Kottage."
United States
Paula M.
The price is SAR 374
SAR 772 total
includes taxes & fees
8 Dec - 9 Dec
The Kitchie Kottage/ House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Portsmouth Hotel Reviews

Ramada by Wyndham Catlettsburg/Ashland

Ramada by Wyndham Catlettsburg/Ashland

10/10 Excellent
"The hotel was supposed to offer breakfast and there was just some stale danishes and cold coffee offered and that was it. "
Steven 2-night trip
Posted 5 days ago
Ramada by Wyndham Catlettsburg/Ashland

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Frequently asked questions

Looking for a spa hotel in Portsmouth?
Book one of our wonderful spa hotels and treat yourself from the moment you arrive. Check out the churches and shopping in Portsmouth—your day trip starts here. Enjoy the riverfront during your vacation. Hotels with spas are the perfect way to take a break from your routine and add a layer of luxury to your weekend away.
What's there to see and do in Portsmouth?
Take in some sights and attractions while you're in Portsmouth by visiting Ohio River, Ohio River Valley, and Portsmouth Floodwall Mural. If you have a little extra time during your trip, you might want to make a stop at Boneyfiddle Commercial District and Earl Thomas Conley Riverside Park.
What is a Portsmouth spa hotel?
Spa hotels in Portsmouth provide lodging and have an on-site spa offering services like therapies as well as beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.