A city skyline with a prominent arch landmark, several high-rise buildings, and boats on a river.

Find Resorts & Hotels with Spas in O'Fallon, IL

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Check availability on O'Fallon Resorts & Hotels with Spas

Our top choices for O'Fallon hotels with a spa

Couples treatment rooms, hot tub, body treatments, aromatherapy

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,001 reviews)
  • cleanliness
    Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
The price is SAR 1,408
SAR 1,647 total
includes taxes & fees
22 Jul - 23 Jul
Four Seasons Hotel St Louis
Restaurant

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1,973 reviews)
  • cleanliness
    Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
The price is SAR 539
SAR 650 total
includes taxes & fees
13 Aug - 14 Aug
21C Museum Hotel St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in O'Fallon

Pool
Hot tub

Top O'Fallon Hotel Reviews

Moonrise Hotel

Moonrise Hotel

10/10 Excellent
"Nice hotel, great location."
Brandon 2-night trip
Posted 11 hours ago
Moonrise Hotel

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Frequently asked questions

Looking for a spa hotel in O'Fallon?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers like the popular shops and gourmet restaurants in O'Fallon. Take in the culture at the art galleries and churches during your stay. Hotels with spas are the perfect way to take a break from your routine and add a layer of luxury to your holiday.
What's there to see and do in O'Fallon?
Enjoy O'Fallon with a stop at O'Fallon Family Sports Park, St. Clair Bowl, and Scott Air Force Base. If you have spare time during your trip, you might want to make a stop at Gateway Arch and Busch Stadium.
What is a O'Fallon spa hotel?
Spa hotels in O'Fallon provide lodging and have a full on-site spa which offers services including couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.