Find Resorts & Hotels with Spas in O'Fallon, IL

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Check availability on O'Fallon Resorts & Hotels with Spas

Tonight
1 Dec - 2 Dec
Tomorrow
2 Dec - 3 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top O'Fallon Resorts & Hotels with Spas

Massages
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1476)
"Awesome hotel. One of the best I've stayed in. However, they need a good chef in both the bar/restaurant and the cafe. Other than the food, it was great. "
United States
Frank
The price is SAR 571
SAR 686 total
includes taxes & fees
28 Dec - 29 Dec
21C Museum Hotel St Louis
Couples treatment rooms, hot tub, body treatments, aromatherapy
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1006)
"The staff was amazing. The bed was so comfortable. "
United States
Mary
The price is SAR 1,557
SAR 1,821 total
includes taxes & fees
2 Jan - 3 January 2026
Four Seasons Hotel St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top O'Fallon Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"The front desk staff was amazing, they were all very kind and helpful. Our room got upgraded for free with a partial view of the arch. Which made my kids extremely happy. The room was really nice and clean. The food was very good with a great selection. My family will definitely be staying again when we go back to Saint Louis. "
Felicia 1-night trip
Posted 2 days ago
Drury Plaza Hotel St. Louis at the Arch

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Frequently asked questions

Looking for a spa hotel in O'Fallon?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers like the popular shops and gourmet restaurants in O'Fallon. Take in the culture at the art galleries and churches during your stay. Hotels with spas are the perfect way to take a break from your routine and add a layer of luxury to your holiday.
What's there to see and do in O'Fallon?
Enjoy O'Fallon with a stop at O'Fallon Family Sports Park, St. Clair Bowl, and Scott Air Force Base. If you have spare time during your trip, you might want to make a stop at Gateway Arch and St. Louis Union Station.
What is a O'Fallon spa hotel?
Spa hotels in O'Fallon provide lodging and have a full on-site spa which offers services including couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.