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Find Resorts & Hotels with Spas in Mount Pleasant, SC

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Check availability on Mount Pleasant Resorts & Hotels with Spas

Our top choices for Mount Pleasant hotels with a spa

A spacious conference room with a large round table and multiple chairs, large windows offering views of a highway and buildings, and a wooden ceiling with recessed lighting.

1. Staybridge Suites Charleston - Mount Pleasant by IHG

Staybridge Suites Charleston - Mount Pleasant by IHG
4.0 star property
Mount Pleasant
9.4 out of 10, Exceptional, (1,000 reviews)
"Really enjoyed our stay here. Room was great as well as everything else!!"
United States
Wesley
The price is SAR 477
SAR 547 total
includes taxes & fees
22 Nov - 23 Nov
Staybridge Suites Charleston - Mount Pleasant by IHG
A swimming pool with lounge chairs and umbrellas, surrounded by trees and a building with multiple windows.

2. Holiday Inn Express & Suites Mt. Pleasant by IHG

Holiday Inn Express & Suites Mt. Pleasant by IHG
3.5 star property
Mount Pleasant
9.2 out of 10, Wonderful, (1,001 reviews)
"I was particularly impressed by the size of our one bedroom suite. Would definitely stay here again."
United States
Michael
The price is SAR 379
SAR 437 total
includes taxes & fees
17 Nov - 18 Nov
Holiday Inn Express & Suites Mt. Pleasant by IHG
An outdoor patio with tables and chairs, palm trees, and a brick building with large windows.

3. Embassy Suites by Hilton Charleston Harbor Mt. Pleasant

Embassy Suites by Hilton Charleston Harbor Mt. Pleasant
3.5 star property
Old Village
9.2 out of 10, Wonderful, (810 reviews)
"Great place to stay in Charleston!"
United States
David
The price is SAR 551
SAR 631 total
includes taxes & fees
13 Dec - 14 Dec
Embassy Suites by Hilton Charleston Harbor Mt. Pleasant
A modern lobby with a candy store, seating area, and a TV screen.

4. Candlewood Suites Charleston Mt Pleasant by IHG

Candlewood Suites Charleston Mt Pleasant by IHG
2.5 star property
Mount Pleasant
9.2 out of 10, Wonderful, (685 reviews)
"Thanks, we had a great stay!"
United States
Justin
The price is SAR 379
SAR 438 total
includes taxes & fees
15 Nov - 16 Nov
Candlewood Suites Charleston Mt Pleasant by IHG
A bar area with wooden stools and a white counter, overlooking a dock and boats.

5. Shem Creek Inn

Shem Creek Inn
3.0 star property
Mount Pleasant
9.2 out of 10, Wonderful, (1,003 reviews)
"We enjoyed our stay at Shem creek inn. Walking distance to so many nice restaurants."
United States
Tracy
The price is SAR 532
SAR 661 total
includes taxes & fees
13 Dec - 14 Dec
Shem Creek Inn
A modern hotel lobby with a round seating area, a chandelier, and a patterned floor.

6. DoubleTree by Hilton Charleston Mount Pleasant

DoubleTree by Hilton Charleston Mount Pleasant
4.0 star property
Mount Pleasant
9.0 out of 10, Wonderful, (1,003 reviews)
"This is a beautiful property. Breakfast is amazing."
United States
Brandon
The price is SAR 339
SAR 391 total
includes taxes & fees
10 Dec - 11 Dec
DoubleTree by Hilton Charleston Mount Pleasant
A modern kitchen with a central island, a chalkboard menu, and a sign promoting waffles.

7. Hampton Inn Charleston/Mount Pleasant-Patriots Point

Hampton Inn Charleston/Mount Pleasant-Patriots Point
2.5 star property
Mount Pleasant
9.0 out of 10, Wonderful, (1,000 reviews)
"Great stay"
United States
Kelly
The price is SAR 397
SAR 456 total
includes taxes & fees
7 Dec - 8 Dec
Hampton Inn Charleston/Mount Pleasant-Patriots Point
A hotel lobby with a bar area, multiple dining tables, and chairs.

8. Hilton Garden Inn Charleston / Mt. Pleasant

Hilton Garden Inn Charleston / Mt. Pleasant
3.0 star property
Mount Pleasant
9.0 out of 10, Wonderful, (1,004 reviews)
"Very clean room, friendly staff and great location."
United States
Katie
The price is SAR 443
SAR 501 total
includes taxes & fees
13 Dec - 14 Dec
Hilton Garden Inn Charleston / Mt. Pleasant
A hotel room with a kitchenette, a bed, a desk, and a dining area.

9. TownePlace Suites Charleston Mt. Pleasant

TownePlace Suites Charleston Mt. Pleasant
3.0 star property
Mount Pleasant
9.0 out of 10, Wonderful, (583 reviews)
"Off the beaten path and quiet"
United States
Brett
The price is SAR 394
SAR 445 total
includes taxes & fees
16 Nov - 17 Nov
TownePlace Suites Charleston Mt. Pleasant
A modern kitchen with a central island, built-in shelves, and a variety of kitchen appliances.

10. Hotel Indigo Mount Pleasant by IHG

Hotel Indigo Mount Pleasant by IHG
3.5 star property
Mount Pleasant
9.0 out of 10, Wonderful, (1,107 reviews)
"Great stay"
United States
Mary Beth
The price is SAR 368
SAR 491 total
includes taxes & fees
13 Dec - 14 Dec
Hotel Indigo Mount Pleasant by IHG
A dining area with wicker chairs, a central table, and hanging wicker chandeliers.

11. Inn at I'On, an Ascend Collection Hotel

Inn at I'On, an Ascend Collection Hotel
3.0 star property
I'On
9.0 out of 10, Wonderful, (512 reviews)
"We enjoyed our visit"
United States
Bice
The price is SAR 804
SAR 925 total
includes taxes & fees
28 Nov - 29 Nov
Inn at I'On, an Ascend Collection Hotel
A spacious lobby with a high ceiling, a mezzanine level, and multiple seating areas including sofas and chairs.

12. Comfort Inn & Suites Patriots Point

Comfort Inn & Suites Patriots Point
2.5 star property
Mount Pleasant
8.8 out of 10, Excellent, (1,274 reviews)
"Hotel was clean and very conveniently located."
United States
Vita
The price is SAR 354
SAR 400 total
includes taxes & fees
6 Dec - 7 Dec
Comfort Inn & Suites Patriots Point
A modern hotel lobby with a dining area, a bar, and a television.

13. Springhill Suites by Marriott Charleston Mount Pleasant

Springhill Suites by Marriott Charleston Mount Pleasant
3.0 star property
Mount Pleasant
8.8 out of 10, Excellent, (1,000 reviews)
"Our room was clean staff was friendly and breakfast was great great place to stay would definitely go back and stay again"
United States
Angela
The price is SAR 382
SAR 439 total
includes taxes & fees
6 Dec - 7 Dec
Springhill Suites by Marriott Charleston Mount Pleasant
A hotel lobby with two armchairs, a reception desk, and a patterned rug.

14. Quality Inn Mt. Pleasant - Charleston

Quality Inn Mt. Pleasant - Charleston
2.5 star property
Mount Pleasant
8.2 out of 10, Very good, (1,757 reviews)
"Great stay!"
United States
GENELL
The price is SAR 305
SAR 352 total
includes taxes & fees
6 Dec - 7 Dec
Quality Inn Mt. Pleasant - Charleston
A hotel reception area with a wooden reception desk, a digital screen, and a wall-mounted sign.

15. Sleep Inn Mt. Pleasant - Charleston

Sleep Inn Mt. Pleasant - Charleston
2.5 star property
Mount Pleasant
8.0 out of 10, Very good, (1,000 reviews)
"Always reliable and pleasant stay"
United States
Marie
The price is SAR 321
SAR 371 total
includes taxes & fees
7 Dec - 8 Dec
Sleep Inn Mt. Pleasant - Charleston
A living room with a sofa, a coffee table with a vase of purple flowers, a window with blinds, and a shelf with snacks.

16. Best Western Patriots Point

Best Western Patriots Point
2.5 star property
Mount Pleasant
8.0 out of 10, Very good, (1,000 reviews)
"A very comfortable place to stay that gives easy access to many local activities."
United States
Michael
The price is SAR 359
SAR 405 total
includes taxes & fees
22 Nov - 23 Nov
Best Western Patriots Point
A hotel room with two beds, a wooden floor, and a large window with curtains.

17. Extended Stay America Suites Charleston Mt Pleasant

Extended Stay America Suites Charleston Mt Pleasant
2.5 star property
Mount Pleasant
7.4 out of 10, Good, (1,016 reviews)
"Great stay"
United States
Michelle
The price is SAR 289
SAR 326 total
includes taxes & fees
18 Nov - 19 Nov
Extended Stay America Suites Charleston Mt Pleasant
A hotel room with a bed, a desk, a chair, a dresser, a microwave, and a television.

18. Red Roof Inn PLUS+ Mt Pleasant - Patriots Point

Red Roof Inn PLUS+ Mt Pleasant - Patriots Point
2.5 star property
Mount Pleasant
6.6 out of 10, (1,000 reviews)
"Ease of check in, helpful staff."
United States
Leroy
The price is SAR 267
SAR 302 total
includes taxes & fees
18 Nov - 19 Nov
Red Roof Inn PLUS+ Mt Pleasant - Patriots Point
A hotel lobby with a reception desk, a ceiling fan, a large mural of a sunset over water, and a wooden floor.

19. Residence Inn by Marriott Charleston Patriots Point

Residence Inn by Marriott Charleston Patriots Point
3.0 star property
Mount Pleasant
9.6 out of 10, Exceptional, (54 reviews)
"We had a great stay! We’ll definitely book again!"
United States
Karen Gay
The price is SAR 635
SAR 726 total
includes taxes & fees
22 Nov - 23 Nov
Residence Inn by Marriott Charleston Patriots Point
A modern bar area with a wooden ceiling, bar stools, and a counter.

20. Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston
3.0 star property
Mount Pleasant
9.4 out of 10, Exceptional, (2,429 reviews)
"Great place to stay!"
United States
william
The price is SAR 390
SAR 445 total
includes taxes & fees
29 Nov - 30 Nov
Cambria Hotel Mount Pleasant – Charleston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Mount Pleasant

Pool
Breakfast included

Top Mount Pleasant Hotel Reviews

The Beach Club at Charleston Harbor Resort and Marina

The Beach Club at Charleston Harbor Resort and Marina

10/10 Excellent
"Rooms are very clean and fashionably decorated to match the beach decor. Beds are also very comfortable and the location is perfect! Water pressure could have been a little better."
Nicole 1-night trip
Posted 3 days ago
The Beach Club at Charleston Harbor Resort and Marina

Frequently asked questions

Looking for a spa hotel in Mount Pleasant?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in Mount Pleasant. Enjoy the historical sites and riverfront during your vacation. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your vacation.
What is the best spa hotel in Mount Pleasant?
The Beach Club at Charleston Harbor Resort and Marina is a top beach spa hotel featuring 3 bars, a 24-hour fitness center, and a restaurant. Treat yourself to a body wrap, couples treatments, or massage at Estuary Spa.
How many spa hotels will I find in Mount Pleasant?
Among Expedia's 419 accommodation options in Mount Pleasant, there is 1 spa hotel.
What's there to see and do in Mount Pleasant?
Experience Mount Pleasant with a stop at Mount Pleasant Towne Centre, Shem Creek Park, and Patriots Point. If you have a little extra time during your trip, you might want to check out USS Yorktown and Charleston Harbor Marina.
What is a Mount Pleasant spa hotel?
Spa hotels in Mount Pleasant provide lodging and have an on-site spa offering services including facials as well as beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.