The Best Hotels Closest to Historic Main Street in St. Louis for 2026

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Our top choices for Historic Main Street hotels

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

1. Drury Plaza Hotel St. Louis St. Charles

1.8 km from Historic Main Street

Madhusudhana Rao

SAR 535 total

includes taxes & fees

14 Dec - 15 Dec

A brick building with a sign reading "Country Inn & Suites."

2. Country Inn & Suites by Radisson, St. Charles Historic District

St. Charles Historic District, 1 km from Historic Main Street

Stewart

SAR 552 total

includes taxes & fees

13 Dec - 14 Dec

A modern kitchen with a central island, breakfast bar, and various appliances.

3. Hampton Inn & Suites St. Charles Old Town Area

1.5 km from Historic Main Street

Sara

SAR 570 total

includes taxes & fees

13 Dec - 14 Dec

A multi-level hotel lobby with numerous seating areas, a central water feature, and a variety of plants.

4. Embassy Suites by Hilton St. Louis St. Charles

2.1 km from Historic Main Street

Terry

SAR 548 total

includes taxes & fees

22 Nov - 23 Nov

An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

5. Ameristar Casino Resort and Spa

1.4 km from Historic Main Street

Carter

SAR 761 total

includes taxes & fees

30 Nov - 1 Dec

A bar area with a long counter, multiple screens, and seating.

6. Hollywood Casino & Hotel St. Louis

3 km from Historic Main Street

Shayla

SAR 377 total

includes taxes & fees

16 Dec - 17 Dec

7. Tru by Hilton St. Charles St. Louis, MO

2.1 km from Historic Main Street

Alissa

SAR 514 total

includes taxes & fees

22 Nov - 23 Nov

A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.

8. Comfort Suites St Charles - St Louis

1.5 km from Historic Main Street

Shawna

SAR 396 total

includes taxes & fees

6 Dec - 7 Dec

A spacious living room with a large sectional sofa, a coffee table, and a fireplace. There is a television mounted on the wall and a chandelier hanging from the ceiling.

9. Best Western Plus The Charles Hotel

1.5 km from Historic Main Street

Steven

SAR 403 total

includes taxes & fees

22 Nov - 23 Nov

A spacious bar area with a long wooden counter, multiple bar stools, and a variety of bar tools.

10. Holiday Inn St. Louis Arpt West-Earth City by IHG

2.9 km from Historic Main Street

marilyn

SAR 328 total

includes taxes & fees

29 Nov - 30 Nov

11. Elimwood Hotel, a Ramada by Wyndham

3.1 km from Historic Main Street

Lucas

SAR 310 total

includes taxes & fees

17 Nov - 18 Nov

A spacious lobby with a reception desk, seating area, and a fireplace.

12. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

1.6 km from Historic Main Street

Gonzalo

SAR 435 total

includes taxes & fees

16 Nov - 17 Nov

A spacious lobby with a central round table, two sofas, and a chandelier.

13. Drury Plaza Hotel St. Louis Chesterfield

15.8 km from Historic Main Street

messia

SAR 566 total

includes taxes & fees

19 Nov - 20 Nov

A modern kitchen with a bar area, wooden cabinets, and pendant lighting.

14. Hyatt Place St. Louis/Chesterfield

15.9 km from Historic Main Street

Karin

SAR 548 total

includes taxes & fees

2 Dec - 3 Dec

A spacious lobby with a high ceiling, a dining area, and a seating area with sofas and a coffee table.

15. Drury Inn & Suites St. Louis St. Peters

12 km from Historic Main Street

Michael

SAR 475 total

includes taxes & fees

22 Nov - 23 Nov

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

16. Pear Tree Inn St. Louis Airport

10.6 km from Historic Main Street

Rebecca

SAR 401 total

includes taxes & fees

19 Nov - 20 Nov

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

17. Wingate by Wyndham St. Louis Airport

10.7 km from Historic Main Street

Cindy

SAR 447 total

includes taxes & fees

23 Nov - 24 Nov

An outdoor patio with a built-in grill, seating area, and stone walls.

18. Residence Inn by Marriott St. Louis Chesterfield

15.1 km from Historic Main Street

Roberta

SAR 830 total

includes taxes & fees

21 Nov - 22 Nov

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

19. Hyatt Select St. Louis Airport

12 km from Historic Main Street

Thadora

SAR 510 total

includes taxes & fees

5 Dec - 6 Dec

A breakfast station with a bakery section, a coffee machine, and a display case with pastries.

20. Holiday Inn Express & Suites St Peters by IHG

15.7 km from Historic Main Street

Roxanne

SAR 502 total

includes taxes & fees

13 Dec - 14 Dec

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Compare popular hotels close to Historic Main Street

Property	Property class	Guest rating
Drury Plaza Hotel St. Louis St. Charles	3.0 star property	9.6 Exceptional 1,004 reviews	View
Country Inn & Suites by Radisson, St. Charles Historic District	2.5 star property	9.4 Exceptional 1,112 reviews	View
Hampton Inn & Suites St. Charles Old Town Area	2.5 star property	9.0 Wonderful 763 reviews	View
Embassy Suites by Hilton St. Louis St. Charles	3.5 star property	8.8 Excellent 1,006 reviews	View
Ameristar Casino Resort and Spa	4.5 star property	8.8 Excellent 1,090 reviews	View

Top Historic Main Street Hotel Reviews

Rustic 2BR on St. Charles Main Street | King & Queen Beds + Free Parking

10/10 Excellent

"Great property!'Thank you!"

Main Street 2BR - Walk to Dining & Riverfront

8/10 Good

"Great location for walking Main Street. The place was clean however, I don’t believe the floors had been mopped before my arrival. The second day I had to pick something off the floor using a paper towel and it was very dirty. More like I had already stayed there more than a week. Also, if you are traveling with a dog, there isn’t anywhere close for your dogs to find grass. There is Main Street, of course, but for dogs to do their business, the best place is on the Katy Trail. That’s great during the day but for evening walks before bed not convenient. Also be aware if staying through Friday or Saturday nights, it gets very loud outside due to Main Street restaurants and bars staying open until 1:30 a.m. This property is directly across from Tony’s and their bar and the Q, are the late night spots. If you’re planning to join in on the fun, no problem but if you’re trying to sleep, not good. The unit has sound machines in their bedrooms which might work for some but the quality is not the best. Overall, the place was nice and up to date. The cleanliness I would have given 5-stars but the dirty floors lowered to 4-stars."

Historic Main 2BR | Free Parking | Brick & Beam

8/10 Good

"The property was very clean. I would have given it five stars however, if you are expecting a restful night this is not the place. We weren’t familiar with the area, and didn’t realize we were staying across the street from a bar with a roof top open until 1am. The walls of this place are very thin, and you will hear every drunken yell. To include some one yelling at pedestrians as they walked by “HEY pick a number between 1 and 8!” Over and over and over. It was about 3 am before things quieted down. There were cars revving their engines just outside the window until 2 am as well. Like I stated before the room is very clean and nice just not the best location if you are expecting a restful getaway."

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

10/10 Excellent

"The rental is small but it worked perfectly for 3. The beds are very comfortable. I was a little worried about the twin beds upstairs- but they were comfortable as well!The location is perfect for strolling around St. Charles historic district. We could shop, drop off bags and head out for more shopping.Very easy checkout."

Other attractions near Historic Main Street

Frontier Park

You can find out about the history of St. Charles with a visit to Frontier Park. Check out the shops and top-notch restaurants in this walkable area.

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Frequently asked questions

What's the area like around Historic Main Street?

Historic Main Street is located in St. Charles. This historic area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 103 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Historic Main Street?

Ameristar Casino Resort and Spa is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and a casino. It's located just a short 0.9 mi (1.4 km) from Historic Main Street. Another good option is Country Inn & Suites by Radisson, St. Charles Historic District, located just 0.6 mi (1 km) away.

How many hotels are there near Historic Main Street?

Expedia has 103 hotels and other accommodations within a mile from Historic Main Street.

If I need to cancel the hotel reservation for my stay near Historic Main Street, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the top deals on offer near Historic Main Street.

Where can I learn more about changing or cancelling my trip in the area near Historic Main Street?

For more information about rescheduling or cancelling your stay near Historic Main Street, click here.

What can I see and do near Historic Main Street?

Sights like First Missouri State Capitol Historic Site and Lewis & Clark Boathouse and Nature Center highlight some of the local culture. Create some family memories at Centene Community Ice Center and Kokomo Joe's Family Fun Center. At Hollywood Casino Amphitheatre, Missouri Artists on Main, and Historic Aircraft Restoration Museum, you'll experience some of the local culture.

Find hotels near Historic Main Street, St. Louis from SAR 310

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Our top choices for Historic Main Street hotels

1. Drury Plaza Hotel St. Louis St. Charles

2. Country Inn & Suites by Radisson, St. Charles Historic District

3. Hampton Inn & Suites St. Charles Old Town Area

4. Embassy Suites by Hilton St. Louis St. Charles

5. Ameristar Casino Resort and Spa

6. Hollywood Casino & Hotel St. Louis

7. Tru by Hilton St. Charles St. Louis, MO

8. Comfort Suites St Charles - St Louis

9. Best Western Plus The Charles Hotel

10. Holiday Inn St. Louis Arpt West-Earth City by IHG

11. Elimwood Hotel, a Ramada by Wyndham

12. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

13. Drury Plaza Hotel St. Louis Chesterfield

14. Hyatt Place St. Louis/Chesterfield

15. Drury Inn & Suites St. Louis St. Peters

16. Pear Tree Inn St. Louis Airport

17. Wingate by Wyndham St. Louis Airport

18. Residence Inn by Marriott St. Louis Chesterfield

19. Hyatt Select St. Louis Airport

20. Holiday Inn Express & Suites St Peters by IHG

Compare popular hotels close to Historic Main Street

Top Historic Main Street Hotel Reviews

Rustic 2BR on St. Charles Main Street | King & Queen Beds + Free Parking

Other attractions near Historic Main Street

Frontier Park

Frequently asked questions