The Best Hotels Closest to Historic Main Street in St. Louis for 2026

A brick-paved street lined with historic buildings and a yellow fire hydrant.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Historic Main Street hotels

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

A spacious lobby with a large sectional sofa, a reception desk, and a bar area.

A gym with treadmills, stationary bikes, and a weight machine.

A hotel pool area with a hot tub, lounge chairs, and a 'No Diving Allowed' sign.

1. Drury Plaza Hotel St. Louis St. Charles

1.8 km from Historic Main Street

Robert

SAR 544

SAR 631 total

includes taxes & fees

25 Oct - 26 Oct

A brick building with a sign reading "Country Inn & Suites."

An indoor swimming pool with a tiled floor, a central window, and multiple chairs around the pool.

A modern kitchen with blue cabinetry, a central island with stools, pendant lighting, and a variety of kitchen appliances and utensils.

A spacious living room with a blue sofa, a white coffee table, and a striped armchair. There is a bookshelf filled with decorative items and a television on a wooden stand.

2. Country Inn & Suites by Radisson, St. Charles Historic District

St. Charles Historic District, 1 km from Historic Main Street

Stewart

SAR 459

SAR 528 total

includes taxes & fees

15 Nov - 16 Nov

A modern kitchen with a central island, breakfast bar, and various appliances.

A snack and drink area with a 'Treats' sign, refrigerated drink dispensers, and shelves stocked with snacks and beverages.

An indoor swimming pool with blue walls, a tiled floor, and lounge chairs.

A modern hotel reception area with a receptionist desk, a large welcome sign, and a view of the cityscape through the glass doors.

3. Hampton Inn & Suites St. Charles Old Town Area

1.5 km from Historic Main Street

Sara

SAR 480

SAR 575 total

includes taxes & fees

1 Nov - 2 Nov

A large hotel building with a prominent sign for 'Embassy Suites.'

A hotel room with a sofa, armchairs, a coffee table, a desk with a chair, a lamp, a painting, and a large window with curtains.

A hotel room with two beds, a desk with a television, a chair, and a large window with curtains.

A spacious lobby with a patterned carpet, a staircase, and an elevator area.

4. Embassy Suites by Hilton St. Louis St. Charles

2.1 km from Historic Main Street

Elyse

SAR 551

SAR 633 total

includes taxes & fees

1 Nov - 2 Nov

A large hotel with a prominent tower and multiple parking areas.

A crowded indoor space with a chandelier, brick walls, and tables where people are seated and standing.

A lobby with a large screen displaying "Hollywood Casino" and "Wood Casino" signs, multiple chandeliers, and a polished floor.

A bar area with a long counter, multiple screens, and seating.

5. Hollywood Casino & Hotel St. Louis

3 km from Historic Main Street

Lindsay

SAR 354

SAR 471 total

includes taxes & fees

1 Nov - 2 Nov

A modern cafe with a self-serve beverage station, a central island with seating, and large windows offering a view.

A modern lounge area with seating arrangements, tables, and hanging pendant lights.

A self-service beverage station with a refrigerated display and a microwave.

6. Tru by Hilton St. Charles St. Louis, MO

2.1 km from Historic Main Street

Kippi

SAR 475

SAR 551 total

includes taxes & fees

15 Nov - 16 Nov

An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

A bar area with multiple seating arrangements, a stage, and a chandelier.

A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.

A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.

7. Ameristar Casino Resort and Spa

1.4 km from Historic Main Street

Melissa

SAR 527

SAR 678 total

includes taxes & fees

19 Nov - 20 Nov

A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A hotel lobby with a wooden floor, a reception desk, two armchairs, a sofa, and large windows with a view of buildings outside.

A lobby with a wooden floor, a reception desk, a seating area with a red sofa, and a glass door leading to another room.

8. Comfort Suites St Charles - St Louis

1.5 km from Historic Main Street

Bryan

SAR 356

SAR 409 total

includes taxes & fees

15 Nov - 16 Nov

A spacious living room with a large sectional sofa, a coffee table, and a fireplace. There is a television mounted on the wall and a chandelier hanging from the ceiling.

A spacious living room with a modern chandelier, a fireplace, and a large television on the wall.

A spacious lobby with a high ceiling, a seating area with sofas and chairs, a reception desk, and a television screen.

A hotel room with a large bed, bedside tables with lamps, a flat-screen TV, and a large window with curtains.

9. Best Western Plus The Charles Hotel

1.5 km from Historic Main Street

Tony

SAR 348

SAR 403 total

includes taxes & fees

27 Oct - 28 Oct

A spacious lobby with a modern design, featuring a large seating area with sofas and chairs, a patterned carpet, and a view of the outside through large windows.

A modern kitchen with white cabinets, a long countertop, and overhead lighting.

10. Elimwood Hotel, a Ramada by Wyndham

3.1 km from Historic Main Street

Harry

SAR 265

SAR 310 total

includes taxes & fees

3 Nov - 4 Nov

A restaurant with a long wooden table, cushioned seating, and decorative lanterns.

A hotel room with a kitchenette, a sofa, a desk, and a large window with curtains.

A hotel room with two beds, a nightstand with a lamp, a framed picture on the wall, and a patterned carpet.

A compact kitchen with dark wooden cabinets, a built-in microwave, and a stainless steel refrigerator.

11. Holiday Inn St. Louis Arpt West-Earth City by IHG

2.9 km from Historic Main Street

Bryan

SAR 349

SAR 405 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with a reception desk, seating area, and a fireplace.

A dining area with round tables and white chairs, a kitchen counter with appliances, and a framed picture on the wall.

A living room with a beige sofa, a wooden coffee table, a patterned rug, a potted plant, and two framed pictures on the wall.

A lobby with a fireplace, several potted plants, a television, and a sofa.

12. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

1.6 km from Historic Main Street

ROSE

SAR 338

SAR 391 total

includes taxes & fees

20 Oct - 21 Oct

An outdoor patio with a built-in grill, seating area, and stone walls.

A multi-story hotel with a parking lot in front.

A spacious lounge area with a stone fireplace, comfortable seating, and a large TV screen.

A modern lobby with a stone accent wall, a flat-screen TV, a reception desk, seating area with sofas and ottomans, and a patterned rug.

13. Residence Inn by Marriott St. Louis Chesterfield

15.1 km from Historic Main Street

Chelsea

SAR 709

SAR 830 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with a central round table, two sofas, and a chandelier.

An indoor swimming pool area with clear signage indicating a depth of 3 feet and a no diving warning.

A Drury Plaza hotel with a modern design, featuring a curved facade, large windows, and a Drury Plaza sign on the top.

A buffet setup with various food items and a decorative vase of flowers.

14. Drury Plaza Hotel St. Louis Chesterfield

15.8 km from Historic Main Street

Chasity

SAR 488

SAR 566 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

15. Pear Tree Inn St. Louis Airport

10.6 km from Historic Main Street

Murphy

SAR 338

SAR 401 total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

16. Wingate by Wyndham St. Louis Airport

10.7 km from Historic Main Street

Rachal

SAR 363

SAR 431 total

includes taxes & fees

25 Oct - 26 Oct

A hotel lobby with a hot tub, a pool, and outdoor seating.

A lobby with seating areas, a reception desk, and a view of the lobby in the background.

A modern lounge area with grey armchairs, a sofa, a TV, and a bookshelf.

A modern coffee shop interior with wooden furniture, a coffee bar, and a sign for 'KELSO+BROS Coffee Roasters'.

17. Drury Plaza Hotel St. Louis Creve Coeur

12.6 km from Historic Main Street

Salvatore

SAR 499

SAR 580 total

includes taxes & fees

26 Oct - 27 Oct

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.

A modern dining area with a long table, multiple chairs, and a unique chandelier.

18. Hyatt Select St. Louis Airport

12 km from Historic Main Street

Daisy

SAR 413

SAR 512 total

includes taxes & fees

26 Oct - 27 Oct

A spacious lobby with a high ceiling, a reception desk, seating areas, and a staircase leading to an upper level.

A hotel room with two beds, a desk, a blue sofa, and a TV.

A modern lobby with a reception desk, seating area, and a dining section.

A coffee station with two coffee machines and a variety of coffee pods and cups.

19. Holiday Inn Express & Suites St Peters by IHG

15.7 km from Historic Main Street

Serah

SAR 443

SAR 532 total

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

A snack vending machine with various snack options.

A hotel lobby with a reception desk, seating area, and a view of the parking lot.

A dining area with tables and chairs, a blue sofa, and a patterned carpet.

20. Hampton Inn By Hilton St Louis Airport

11.7 km from Historic Main Street

Judith

SAR 428

SAR 515 total

includes taxes & fees

19 Nov - 20 Nov

View all properties

Compare popular hotels close to Historic Main Street

Property	Property class	Guest rating
Drury Plaza Hotel St. Louis St. Charles	9.6 Exceptional 1,002 reviews	View
Country Inn & Suites by Radisson, St. Charles Historic District	9.4 Exceptional 1,105 reviews	View
Hampton Inn & Suites St. Charles Old Town Area	9.0 Wonderful 751 reviews	View
Embassy Suites by Hilton St. Louis St. Charles	8.8 Excellent 1,002 reviews	View
Hollywood Casino & Hotel St. Louis	8.6 Excellent 2,227 reviews	View

Top Historic Main Street Hotel Reviews

Riverwood Retreat | Main Street 2BR

10/10 Excellent

"Very Good apt! Near everything!"

The Rustic Revival | Charming 2BR Retreat

10/10 Excellent

"Perfect downtown stay! Lots of shopping, food and bars within walking distance. Love that the rooms had a sound machine!"

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

10/10 Excellent

"Beautiful place and close to shops and dining!"

The Oak & Aura Retreat

10/10 Excellent

"The room was great. Very good location for the Oktoberfest. Very clean. We love the stay great communications."

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

10/10 Excellent

"Loved this historical cottage in St. Charles, just walking to great restaurants and shops was extra bonus with the lovely rental. In the morning I sat with coffee looking at the river. Wonderful."

The St. Charles Guest House, lovely historic home, fun for families and groups

10/10 Excellent

"They were excellent hosts and great communication!! I highly recommend this house!"

Main Street 2BR - Walk to Dining & Riverfront

10/10 Excellent

"This is our new favorite property in St. Charles. Between the location, size of the space and the designated parking spot, we will definitely be staying here again!"

The Fox Den Suite — Cozy, playful, and memorable.

8/10 Good

"Great place right on Main Street. Bed was very comfortable. Couch is like a mini couch, very low to the ground and not what’s in the listing picture. As others have mentioned it is very noisy on Friday and Saturday nights with the bar next door. Parking was a little chaotic due to the craft show going on all weekend, but not the hosts fault. It would be nice if there was reserved parking for those staying at the Outter. Overall the place is cute, clean, comfortable bed, and great bathroom."

The Foundry Flat | Industrial-Inspired 2-Bedroom

10/10 Excellent

"Everything was exactly as described. St. Charles is an awesome place!"

Other attractions near Historic Main Street

Frontier Park

You can find out about the history of St. Charles with a visit to Frontier Park. Check out the shops and top-notch restaurants in this walkable area.

See properties

A steel bridge over a calm river with lush greenery and trees in the background.

Katy Trail

9.0/10 (158 reviews)

You can take time to visit Katy Trail during your travels to St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.

See properties

First Missouri State Capitol Historic Site

8.2/10 (25 reviews)

You can learn about the history of St. Charles when you stop by First Missouri State Capitol Historic Site. Discover the top-notch restaurants and acclaimed theater scene in this family-friendly area.

See properties

Missouri Artists on Main

You can spend an afternoon browsing the exhibits at Missouri Artists on Main in St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.

See properties

Lewis & Clark Boathouse and Nature Center

8.8/10 (113 reviews)

You can spend time exploring the galleries in Lewis & Clark Boathouse and Nature Center during your travels in St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.

See properties

Frenchtown Heritage Museum

You can spend time browsing the exhibits at Frenchtown Heritage Museum during your trip to St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.

See properties

Lindenwood University

8.6/10 (183 reviews)

Walk around the campus at Lindenwood University during your stay in St. Charles. Experience the acclaimed theater scene and great live music in this family-friendly area.

See properties

St Charles Convention Center

8.4/10 (223 reviews)

After visiting St Charles Convention Center, make a plan to see the other sights and activities in St. Charles. Discover the top-notch restaurants and great live music in this family-friendly area.

See properties

Frequently asked questions

What's the area like around Historic Main Street?

Historic Main Street is located in St. Charles. This historic area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 103 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Historic Main Street?

Ameristar Casino Resort and Spa is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and a casino. It's located just a short 0.9 mi (1.4 km) from Historic Main Street. Another good option is Country Inn & Suites by Radisson, St. Charles Historic District, located just 0.6 mi (1 km) away.

How many hotels are there near Historic Main Street?

Expedia has 103 hotels and other accommodations within a mile from Historic Main Street.

If I need to cancel the hotel reservation for my stay near Historic Main Street, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the top deals on offer near Historic Main Street.

Where can I learn more about changing or cancelling my trip in the area near Historic Main Street?

For more information about rescheduling or cancelling your stay near Historic Main Street, click here.

What can I see and do near Historic Main Street?

Sights like First Missouri State Capitol Historic Site and Lewis & Clark Boathouse and Nature Center highlight some of the local culture. Create some family memories at Centene Community Ice Center and Kokomo Joe's Family Fun Center. At Hollywood Casino Amphitheatre, Missouri Artists on Main, and Historic Aircraft Restoration Museum, you'll experience some of the local culture.

Find hotels near Historic Main Street, St. Louis from SAR 310

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Historic Main Street hotels

1. Drury Plaza Hotel St. Louis St. Charles

2. Country Inn & Suites by Radisson, St. Charles Historic District

3. Hampton Inn & Suites St. Charles Old Town Area

4. Embassy Suites by Hilton St. Louis St. Charles

5. Hollywood Casino & Hotel St. Louis

6. Tru by Hilton St. Charles St. Louis, MO

7. Ameristar Casino Resort and Spa

8. Comfort Suites St Charles - St Louis

9. Best Western Plus The Charles Hotel

10. Elimwood Hotel, a Ramada by Wyndham

11. Holiday Inn St. Louis Arpt West-Earth City by IHG

12. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

13. Residence Inn by Marriott St. Louis Chesterfield

14. Drury Plaza Hotel St. Louis Chesterfield

15. Pear Tree Inn St. Louis Airport

16. Wingate by Wyndham St. Louis Airport

17. Drury Plaza Hotel St. Louis Creve Coeur

18. Hyatt Select St. Louis Airport

19. Holiday Inn Express & Suites St Peters by IHG

20. Hampton Inn By Hilton St Louis Airport

Compare popular hotels close to Historic Main Street

Top Historic Main Street Hotel Reviews

Riverwood Retreat | Main Street 2BR

The Rustic Revival | Charming 2BR Retreat

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

The Oak & Aura Retreat

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

The St. Charles Guest House, lovely historic home, fun for families and groups

Main Street 2BR - Walk to Dining & Riverfront

The Fox Den Suite — Cozy, playful, and memorable.

The Foundry Flat | Industrial-Inspired 2-Bedroom

Other attractions near Historic Main Street

Frontier Park

Katy Trail

First Missouri State Capitol Historic Site

Missouri Artists on Main

Lewis & Clark Boathouse and Nature Center

Frenchtown Heritage Museum

Lindenwood University

St Charles Convention Center

Frequently asked questions