Photo by throwingsofas

Find Casinos in Grand Center, MO

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Grand Center Casinos

Our top choices for Grand Center hotels with a casino

Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1241)
"Great hospitality"
United States
Alejandro
The price is SAR 402
SAR 478 total
includes taxes & fees
24 Dec - 25 Dec
Embassy Suites by Hilton St. Louis Downtown
Casino
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 star property
Maryland Heights
8.4 out of 10, Very Good, (2215)
"Front staff was very friendly and very helpful. Check-in and check out was smooth and very easy. "
United States
James
The price is SAR 394
SAR 514 total
includes taxes & fees
6 Jan - 7 January 2026
Hollywood Casino & Hotel St. Louis
Exterior
Best Western Plus St. Louis Airport Hotel

Best Western Plus St. Louis Airport Hotel

2.5 star property
Woodson Terrace
9.2 out of 10, Wonderful, (1006)
"Room was nice and comfortable, pool was awesome, and breakfast left us all happy"
United States
Letez
The price is SAR 412
SAR 509 total
includes taxes & fees
19 Dec - 20 Dec
Best Western Plus St. Louis Airport Hotel
Free daily buffet breakfast
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1000)
"Love this hotel. "
United States
Lisa
The price is SAR 441
SAR 507 total
includes taxes & fees
1 Jan - 2 January 2026
Country Inn & Suites by Radisson, St. Charles Historic District
Casino
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 star property
St. Charles
8.4 out of 10, Very Good, (1003)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is SAR 571
SAR 730 total
includes taxes & fees
14 Dec - 15 Dec
Ameristar Casino Resort and Spa
Lobby
The Great Rivers, an Ascend Collection Hotel

The Great Rivers, an Ascend Collection Hotel

3.0 star property
Alton
7.8 out of 10, Good, (758)
"The hotel is being remodeled, so it's hard to give it a fair review."
United States
Stephen
The price is SAR 316
SAR 360 total
includes taxes & fees
4 Jan - 5 January 2026
The Great Rivers, an Ascend Collection Hotel
Blackout drapes, free WiFi, bed sheets
Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach

2.5 star property
Granite City
7.8 out of 10, Good, (572)
"Room was clean, staff were really nice & helpful!! We will be back!"
United States
Shkaia
The price is SAR 236
SAR 268 total
includes taxes & fees
12 Dec - 13 Dec
Red Lion Inn & Suites Pontoon Beach
Lobby
AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End

4.0 star property
Central West End
9.0 out of 10, Wonderful, (682)
"Clean room, Helpful staff, Easy/cheap parking "
United States
Delaney
The price is SAR 477
SAR 562 total
includes taxes & fees
20 Dec - 21 Dec
AC Hotel St. Louis Central West End
Casino
Casino Queen Hotel

Casino Queen Hotel

3.0 star property
East St. Louis
7.6 out of 10, Good, (1974)
"Clean room, friendly staff, lobby was nice and welcoming. "
United States
Tricia
The price is SAR 316
SAR 366 total
includes taxes & fees
11 Dec - 12 Dec
Casino Queen Hotel
Exterior
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

2.5 star property
St. Charles
8.4 out of 10, Very Good, (1006)
"Nice staff at reception. "
United States
Denise
The price is SAR 327
SAR 376 total
includes taxes & fees
16 Dec - 17 Dec
Comfort Suites St Charles - St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Grand Center Hotel Reviews

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10/10 Excellent
"The shuttle service was timely and useful. Landon,at the front desk, did an amazing job helping us with our issues with Expedia! He was very personable and helpful!"
Joseph 1-night trip
Posted 21 hours ago
Pear Tree Inn St. Louis Airport

Explore a world of travel with Expedia

Frequently asked questions

Searching for casino hotels in Grand Center?
Headed to Grand Center for some gaming? As luck would have it, you'll find Horseshoe St. Louis Casino, Casino Queen, and River City Casino in the area, as well as lots more to see and do. Visitors enjoy the theaters, entertainment venues, and art galleries. You might want to visit popular sights in the larger area including St. Louis Union Station and Gateway Arch.
How many hotels that are good for gaming will I be able to find in Grand Center?
You won't need a stroke of luck to find something that suits with one of Expedia's 31 accommodations near casino gaming in Grand Center.
What is there to do in Grand Center?
You can head to Washington Avenue Historic District, Ballpark Village, or Soulard Farmer's Market to shop for the perfect souvenir. Grand Center is known for its theaters, entertainment venues, and art galleries, and you can check out cultural spots such as Sheldon Concert Hall and Fox Theater. For more to see and do, you can plan to visit Powell Symphony Hall and St. Louis Symphony Orchestra.