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Find Resorts & Hotels with Spas in Grand Center, MO

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Check availability on Grand Center Resorts & Hotels with Spas

Tonight
7 Dec - 8 Dec
Tomorrow
8 Dec - 9 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Top Grand Center Resorts & Hotels with Spas

Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 star property
St. Charles
8.4 out of 10, Very Good, (1001)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is SAR 571
SAR 730 total
includes taxes & fees
14 Dec - 15 Dec
Ameristar Casino Resort and Spa
Massages
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1483)
"Staff is wonderful. We checked in late after a long journey and they could not have been nicer to us at check in also in the restaurant and bar. We loved the vibe and the location. I’d return again if ever in the area. "
United States
Jenifer
The price is SAR 475
SAR 575 total
includes taxes & fees
28 Dec - 29 Dec
21C Museum Hotel St Louis
Couples treatment rooms, hot tub, body treatments, aromatherapy
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1002)
"The staff was amazing. The bed was so comfortable. "
United States
Mary
The price is SAR 1,558
SAR 1,821 total
includes taxes & fees
1 Jan - 2 January 2026
Four Seasons Hotel St Louis
Body treatments, aromatherapy, hot stone massages, deep-tissue massages
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5.0 star property
Clayton
9.2 out of 10, Wonderful, (553)
"Service is exceptional!!!"
United States
Jorge
The price is SAR 1,873
SAR 2,186 total
includes taxes & fees
21 Dec - 22 Dec
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Grand Center Hotel Reviews

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent
"Clean Room, the view was amazing, the game room was perfect to help calm my daughter the morning of her procedure at the Children’s Hospital. "
Shane 1-night trip
Posted 1 day ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

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Frequently asked questions

Looking to vacation at a spa hotel in Grand Center?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the theater scene and opera in Grand Center—your cultural tour starts here. Take in the culture at the art galleries and churches during your stay. Spa hotels are a great way to break out of your daily routine and add a layer of luxury to your holiday.
What's there to see and do in Grand Center?
Experience Grand Center and visit Powell Symphony Hall, St. Louis Symphony Orchestra, and Sheldon Concert Hall. If you have spare time during your trip, you might want to make a stop at Fox Theater and Grandel Theater.
What is a Grand Center spa hotel?
Spa hotels in Grand Center have full on-site spas offering services including therapies and a range of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.