A bridge over a muddy river with green trees and hills in the background.

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Check prices for these dates

Next weekend
2 Oct - 4 Oct
In two weeks
9 Oct - 11 Oct

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Our top choices for Mississippi County hotels

Laptop workspace, blackout drapes, cribs (free), WiFi (free)

1. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (669 reviews)
"This place was so dirty and in much need of repair. We got in late or there’s no way we would have stayed here. They tried to use perfume to cover up the smell but it made it so much worse!"
United States
William
The price is SAR 223
SAR 248 total
includes taxes & fees
27 Sep - 28 Sep
Super 8 by Wyndham Charleston/Sikeston East MO
Exterior

2. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (435 reviews)
"Everything was fine for a one night stay."
United States
Jay
The price is SAR 250
SAR 277 total
includes taxes & fees
29 Sep - 30 Sep
The Riverstone Hotel Charleston-Sikeston
Room, 1 King Bed, Non Smoking | View from room

3. Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (107 reviews)
"Great"
United States
Jackson
The price is SAR 248
SAR 275 total
includes taxes & fees
23 Oct - 24 Oct
Eagle Inn Charleston
Lobby

4. Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (295 reviews)
"Good service,nice stuff and no complaints"
United States
Santiago
The price is SAR 266
SAR 295 total
includes taxes & fees
23 Oct - 24 Oct
Quality Inn Cairo I-57
Fridge, stovetop

5. The Roost | Hot Tub, Ponds & Farm Views

The Roost | Hot Tub, Ponds & Farm Views
Carlisle County
The price is SAR 537
SAR 781 total
includes taxes & fees
27 Oct - 28 Oct
The Roost | Hot Tub, Ponds & Farm Views
Terrace/patio

6. Perfect Couples Retreat - firepit

Perfect Couples Retreat - firepit
Carlisle County
The price is SAR 461
SAR 700 total
includes taxes & fees
27 Sep - 28 Sep
Perfect Couples Retreat - firepit
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mississippi County Hotel Reviews

Hampton Inn Union City

Hampton Inn Union City

10/10 Excellent
"I have stayed at this several times and every time the rooms were super clean, I was walking around the room in my bare feet, and I stay in a lot of motels/hotels and I cant do that in most. We were very pleased with the room, and will stay again if we are near the area."
Clarence 2-night trip
Posted 7 hours ago
Hampton Inn Union City