Find 5 Star Hotels in Florida Keys from SAR 1,305

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Check availability on Florida Keys 5 Star Hotels

Our top choices for Florida Keys 5-star hotels

Balcony

Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,311 reviews)
"Great staff and beautiful property "
United States
Julie
The price is SAR 1,133
SAR 1,549 total
includes taxes & fees
12 Apr - 13 Apr
Cheeca Lodge & Spa
On the beach, sun loungers, beach umbrellas, beach towels

Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa
5.0 star property
Marathon
9.2 out of 10, Wonderful, (1,097 reviews)
"great resort "
United States
Niki
The price is SAR 1,678
SAR 2,143 total
includes taxes & fees
12 Apr - 13 Apr
Isla Bella Beach Resort & Spa
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Florida Keys.
Reefhouse Resort & Marina

Reefhouse Resort & Marina

103800 Overseas Hwy Key Largo FL
The price is SAR 1,422 per night from Apr 12 to Apr 13
SAR 1,422
SAR 1,750 total
12 Apr - 13 Apr
includes taxes & fees
9.4/10 Exceptional! (1,380 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colorful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

See all hotels in Florida Keys
Higgs Beach showing a sandy beach and tropical scenes as well as a large group of people

Top Florida Keys Hotel Reviews

Cheeca Lodge & Spa

Cheeca Lodge & Spa

10/10 Excellent
"All 3 pools were excellent. The sandy beach looking over the Atlantic Ocean was amazing and relaxing at the same time. The ladies went to the spa the men played the par 3 course, which is included in the resort fee."
Marty 5-night trip
Posted 1 day ago
Cheeca Lodge & Spa
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

8/10 Good
"All rooms have an ocean view-beautiful for sure!"
Wanda 5-night trip
Posted 3 days ago
Isla Bella Beach Resort & Spa

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Florida Keys?
The amount you pay for a 5-star hotel in Florida Keys can vary depending on the time of year you travel and how long you plan to be away, among other factors. Use our price per night filter and other search tools to score the best deal on a luxurious stay.

  • Search for the lowest price per night from SAR 1,305

What makes a hotel 5 stars in Florida Keys?
In Florida Keys, a hotel needs to provide a specific level of upscale amenities to earn a 5-star rating. These may include gourmet restaurants, saunas and spas, on-site gyms, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their outstanding service. You'll enjoy things like concierge services, nightly turn-down services and in-room massage. Some may even offer special touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Florida Keys?
Expedia's filters are the best way to narrow down what you're looking for. Select "5-star" and "All inclusive" to see the most luxurious properties in Florida Keys where your meals, room, activities and entertainment are included in the price. At these stays, your vacation is absolute indulgence from the moment you put down your suitcase.

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