Find 5 Star Hotels in Defiance, MO from SAR 600
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Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Defiance.
Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
SAR 561
SAR 718 total
12 Oct - 13 Oct
includes taxes & fees
8.6/10 Excellent! (1,054 reviews)
Hilton St. Louis Frontenac
1335 S Lindbergh Blvd Frontenac MO
SAR 551
SAR 642 total
27 Sep - 28 Sep
includes taxes & fees
8.8/10 Excellent! (1,000 reviews)
DoubleTree by Hilton St. Louis - Westport
1973 Craigshire Rd Maryland Heights MO
SAR 517
SAR 600 total
27 Sep - 28 Sep
includes taxes & fees
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighboring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.
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Frequently asked questions
How much does it cost to stay in a 5-star hotel in Defiance?
The amount you pay for a 5-star hotel in Defiance depends on things such as when you want to go and the length of your vacation. Our insider tip for scoring an awesome deal? Use our pricing filters to check out the available hotels for your preferred dates.
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What makes a hotel 5 stars in Defiance?
In Defiance, a hotel must provide a specific number of upscale conveniences to earn 5 stars. These can include gourmet restaurants, on-site gyms, saunas and spas, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their outstanding standard of service. You can look forward to things like in-room massages, nightly turn-down services and concierge services. Some may even offer extra touches like welcome gifts.
Are there any 5-star all-inclusive resorts in Defiance?
Our handy filters are the best way to find exactly what you're looking for. Check the "All inclusive" and "5-star" boxes to see the most upscale resorts in Defiance where your accommodations, meals, entertainment and activities are included in the upfront price. At these escapes, your trip is pure relaxation and indulgence from the moment you pull up to the entrance.